Maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes: A cross-sectional study

Background: Pregnancy is a process associated with various metabolic and hormonal changes, and polycystic ovary syndrome (PCOS) can affect this process. Objective: This study aimed to evaluate and compare the maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes. Materials and Methods: In this cross-sectional study, 200 pregnant women with PCOS according to the 2003 ESHRE/ASRM criteria were categorized into four phenotype groups (A-D). The maternal outcomes include gestational diabetes mellitus, pregnancy-induced hypertension, premature rupture of membranes, preterm labor, small-for-gestational age birth, intrauterine growth restriction, intrauterine mortality, preeclampsia, abortion, amniotic fluid disorders, delivery method, and cause of cesarean section were studied between groups. Additionally, neonatal outcomes such as neonatal weight, neonatal recovery, 5-min Apgar score, neonatal icter, the need for NICU admission, the cause of hospitalization, and infant mortality rate were investigated and compared among the groups. Results: According to the results, phenotype D (37%) was the most common phenotype among the participants. The risk of gestational diabetes was more common in phenotype A than in the other phenotypes, whereas pregnancy-induced hypertension was most common in phenotype B. No significant differences were observed in the neonatal complications among the PCOS phenotypes. Conclusion: Considering the higher risk of gestational diabetes mellitus and pregnancy-induced hypertension in PCOS phenotypes A and B, women with these phenotypes need more precise prenatal care. Key words: Pregnancy outcome, Polycystic ovary syndrome, Phenotype, Pregnancy.

Download Full-text

Risks for Gestational Diabetes Mellitus and Pregnancy-Induced Hypertension Are Increased in Polycystic Ovary Syndrome

BioMed Research International ◽

10.1155/2013/182582 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 14

Author(s):

Yunhui Wang ◽

Xiaomiao Zhao ◽

Huidan Zhao ◽

Hong Ding ◽

Jianping Tan ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Polycystic Ovary Syndrome ◽

Gestational Diabetes Mellitus ◽

Ovarian Stimulation ◽

Polycystic Ovary ◽

Pregnancy Induced Hypertension ◽

Ovary Syndrome ◽

Induced Hypertension ◽

Ivf Et

Objectives. To evaluate pregnancy outcomes and its determinants in women with polycystic ovary syndrome (PCOS).Methods. Two-hundred and twenty pregnant PCOS and 594 healthy women were followed from early pregnancy. Incidences of gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), preterm birth, twinning, and fetal growth restriction (FGR) were determined.Results. The incidence of GDM was notably higher among all PCOS combined (54.9%; OR: 2.9, 95% CI: 2.0–4.1) and PCOS subgroups, whether they conceived spontaneously (51.5%; OR: 3.3, 95% CI: 2.0–5.4), or via IVF-ET or ovarian stimulation, compared with controls (14.3%;P<0.001). The incidence of PIH was also higher among all PCOS (10.4%; OR: 2.2, 95% CI: 1.1–4.4) and the subgroup conceiving spontaneously (11.8%; OR: 2.6, 95% CI: 1.1–6.2;P<0.001) but not for those conceiving with IVF-ET (9.1%) or ovarian stimulation (9.4%). Lean women with PCOS (BMI<24kg/m2) had higher incidences of GDM (51.1% versus 14.5%; OR: 5.6, 95% CI: 3.4–9.0) and PIH (8.9% versus 3.2%; OR: 3.0, 95% CI: 1.3–7.1) than lean controls. PCOS woemn with normal glucose tolerance had higher risk for PIH than their comparable control group (OR: 4.0, 95% CI: 1.3–11.7).Conclusion. This study suggested that PCOS is an independent risk factor for the development of GDM and PIH. This trial is registered withChiCTR-RCC-11001824.

Download Full-text

Predictors of Gestational Diabetes Mellitus in Chinese Women with Polycystic Ovary Syndrome: A Cross-Sectional Study

Gynecologic and Obstetric Investigation ◽

10.1159/000440618 ◽

2015 ◽

Vol 81 (3) ◽

pp. 220-224 ◽

Cited By ~ 4

Author(s):

Ya-jie Zhang ◽

Hua Jin ◽

Zhen-li Qin ◽

Jin-long Ma ◽

Han Zhao ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Polycystic Ovary Syndrome ◽

Gestational Diabetes Mellitus ◽

Chinese Women ◽

Polycystic Ovary ◽

Cross Sectional Study ◽

Sectional Study ◽

Ovary Syndrome ◽

Cross Sectional

Download Full-text

Incidence of Pregnancy Induced Hypertensive Women and its Associated Factors

10.53350/pjmhs2115123307 ◽

2021 ◽

Vol 15 (12) ◽

pp. 3307-3309

Author(s):

Samia Saifullah ◽

Maryam Shoaib ◽

Muhammad Sohail Tareen ◽

Nosheen Sikander Baloch

Keyword(s):

Blood Pressure ◽

Family History ◽

Pregnant Women ◽

Cross Sectional Study ◽

Mean Value ◽

Renal Diseases ◽

Pregnancy Induced Hypertension ◽

Cross Sectional ◽

Induced Hypertension ◽

Keywords Pregnancy

Background: Pregnancy induced hypertension is a fetal disease resulting into morbidity and mortality of female as well as its neonate. Objective: To find the incidence of pregnancy induced hypertension in Pakistani women. Study Design: Cross sectional study Place and Duration of the Study: Department of Obstetrics & Gynaecology, Sandeman Provincial Hospital, Quetta from 1st March 2019 to 31st March 2021. Methodology: Seven hundred and twenty eight females were identified with pregnancy induced hypertension from all the pregnant women attending the outdoor were enrolled. Each female was checked for their protein urea as well as systolic and diastolic blood pressure according to standard operating protocol. Socio-demographic, clinical and family history were documented. Results: Among all pregnant women, 150 were identified as pregnancy induced hypertensive with a 20.6% incidence of pregnancy induced hypertension. The mean value systolic blood pressure value was 144.3±5.2 and of diastolic as 83.1±5.2 in pregnancy induced hypertension women. Conclusion: Family history, obesity and renal diseases are the main factors associated with pregnancy induced hypertension with an incidence of 20.6% among pregnant women. Keywords: Pregnancy induced hypertension, Body mass index, Pregnant women, Hypertension

Download Full-text

Factors influencing self-consciousness in polycystic ovary syndrome (PCOS): A cross-sectional study.

SSRN Electronic Journal ◽

10.2139/ssrn.3930759 ◽

2021 ◽

Author(s):

Mohammed Abdalla ◽

Harshal Deshmukh ◽

Thozhukat Sathyapalan

Keyword(s):

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Cross Sectional Study ◽

Sectional Study ◽

Ovary Syndrome ◽

Cross Sectional ◽

Factors Influencing

Download Full-text

Assessment of Prevalence of Hypertension in pregnant women with its Complications: A Cross Sectional Study

Research Journal of Pharmacy and Technology ◽

10.52711/0974-360x.2021.00659 ◽

2021 ◽

pp. 3805-3808

Author(s):

Hemalatha S. ◽

S. M. Shaheedha ◽

Ramakrishna Borra

Keyword(s):

Pregnant Women ◽

Cross Sectional Study ◽

World Health ◽

Chronic Hypertension ◽

Pregnancy Induced Hypertension ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Gynecology And Obstetrics ◽

Induced Hypertension ◽

History Of

Introduction: World Health Organization has reported that pregnancy induced hypertension is one of the main causes for mortality and morbidity in maternal and fetal deaths. About 60% of deaths accounted of eclampsia. Aims and Objectives: To diagnose for hypertension in pregnant women. To evaluate the knowledge of pregnancy induced hypertension among the pregnant women. To investigate the complications reported in Pregnancy induced hypertension (PIH) women, during and after labor. Study area and period: The present study was conducted in Chittoor government hospital, Chittoor, during the period of Jan 2016 and Dec 2017. The information and materials required for the study have been collected from the gynecology and obstetrics departments of the respective hospital. Results: During the study period of Jan 2016 and Dec 2017, about 2234 number of pregnant women have visited the obstetrics and gynecology department. All the 2234 pregnant women were tested for blood pressure. Among which 198 women were found to have hypertension, which may be of early onset PIH or chronic hypertension (HTN). Different variables of the study population like period of gestation [<20 weeks, ≥20 weeks], previous cesarean section if present, previous preterm delivery if present, hypertension in previous pregnancy, history of paternal hypertension, history of abortions if have been, history of any still births, family history of PIH have been noted and reported in table 2. More than 8% of women were found to been falling in <20 weeks of gestational age (GA). Conclusion: The study included 2234 pregnant women, in which 198 women were diagnosed with hypertension. Thus, prior investigation and identification hypertension in pregnant women helps in better management of PIH and to overcome the complications that are reported due to PIH during and after labor. Better knowledge and treatment is required for managing hypertension in maternal women in gynecology and obstetrics department for maternal and fetal care.

Download Full-text

Physical activity and sedentary behaviour in women with and without polycystic ovary syndrome: An Australian population‐based cross‐sectional study

Clinical Endocrinology ◽

10.1111/cen.14205 ◽

2020 ◽

Vol 93 (2) ◽

pp. 154-162

Author(s):

Chau Thien Tay ◽

Lisa J. Moran ◽

Cheryce L. Harrison ◽

Wendy J. Brown ◽

Anju E. Joham

Keyword(s):

Physical Activity ◽

Polycystic Ovary Syndrome ◽

Sedentary Behaviour ◽

Polycystic Ovary ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Ovary Syndrome ◽

Australian Population ◽

Cross Sectional

Download Full-text

Prevalence of Self-reported Polycystic Ovary Syndrome and Profiles of Health Among Women of Different Generations: A Cross Sectional Study

Fertility & Reproduction ◽

10.1142/s2661318219500154 ◽

2019 ◽

Vol 01 (03) ◽

pp. 141-147

Author(s):

Jodie C. Avery ◽

Lisa J. Moran ◽

Vivienne Moore ◽

Renae C. Fernandez ◽

Melissa Whitrow ◽

...

Keyword(s):

Cardiovascular Disease ◽

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Age Groups ◽

South Australia ◽

Cross Sectional Study ◽

Age Group ◽

Ovary Syndrome ◽

Cross Sectional ◽

Younger Women

Objective: Although polycystic ovary syndrome (PCOS) is considered a lifelong disorder, very little is understood about the diagnosis and impact of this condition in women outside of the peak reproductive years. We examined the frequency of diagnosed PCOS and concurrent health conditions in women across the lifespan. Methods: Data were analysed from 1509 women aged 15–95 years participating in a cross-sectional, face-to-face population survey in South Australia, 2015. We assessed the prevalence of PCOS in 10-year age groups and the frequency of comorbidities in women with and without PCOS subgrouped by age (< 45, [Formula: see text] 45 years). The main outcome measures were Diagnosed PCOS and other chronic conditions; lifestyle factors. Logistic regression analyses determined the risk of comorbidities in women with PCOS adjusting for age and BMI. Results: Overall prevalence of PCOS was 5.6% (95% confidence interval (CI) 4.6–6.9%), peaking in the 35–44 year age group (9.1%), and lowest in those aged 15–24 (4.1%) or [Formula: see text] 65 (3.7%) years. Women with PCOS and aged <45 years were more likely to report diabetes (16.7% vs. 3.8%), cardiovascular disease (15.5% vs. 7.2%) and arthritis (15.5% vs. 7.2%) than their peers; these differences were diminished in the [Formula: see text] 45 year age group. The odds of diabetes and cardiovascular disease were more than doubled among women with PCOS (adjOR 2.23, 95% CI 1.49–4.31; adjOR 3.18, 95% CI 1.31–7.68). Conclusion: PCOS is underdiagnosed in young and post-menopausal women. Diabetes and cardiovascular disease are key comorbidities requiring greater attention in younger women with PCOS.

Download Full-text