scholarly journals Drug Utilization Evaluation of Antibiotics in Intensive Care Units of a Referral Teaching Hospital

2021 ◽  
Author(s):  
Rasool Soltani ◽  
Atousa Hakamifard ◽  
Sarah Mousavi ◽  
Zohreh Amani
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Drug Utilization ◽  
Teaching Hospital ◽  
Dose Adjustment ◽  
Sensitivity Test ◽  
High Rate ◽  
Microbial Culture ◽  
Collection Form ◽  
Drug Utilization Evaluation

Background: Drug Utilization Evaluation (DUE) studies are designed to assess drug usage appropriateness. This study aimed to evaluate the drug utilization of antibiotics in the intensive care units (ICUs) of a referral teaching hospital. Methods: Patients hospitalized in ICU who received antibiotics were enrolled in this crosssectional study. Patients’ medical charts were reviewed and data including indication of antibiotics, dosing, dose adjustment, and culture sensitivity test were recorded in a predesigned data collection form. Related guidelines and references were used for judgement about the correctness of these parameters. Results: Among 182 evaluated antibiotic prescriptions, 75.8% of the cases were prescribed empirically that for 31.88% of them microbial culture and sensitivity test were requested. Indication was appropriate in 51.6%. Fifteen patients needed antibiotic dose adjustment that was performed just for 4 patients. Doses of antibiotics were correct in 58.5% of cases. Meropenem (15.9%), Metronidazole (15.9%), and vancomycin (11.5%) were the most frequently prescribed antibiotics. Conclusion: Use of antibiotics in ICUs of our hospital is associated with high rate of errors especially in the aspects of medical indication and dosage. J

Comparison of antimicrobial resistance in neonatal and adult intensive care units in a tertiary teaching hospital

2012 ◽  
Vol 40 (6) ◽  
pp. 572-575 ◽  
Author(s):  
Noorzaitun Ariffin ◽  
Habsah Hasan ◽  
Noraida Ramli ◽  
Nor Rosidah Ibrahim ◽  
Fahisham Taib ◽  
...  
Keyword(s):  
Intensive Care ◽  
Antimicrobial Resistance ◽  
Intensive Care Units ◽  
Teaching Hospital ◽  
Tertiary Teaching ◽  
Tertiary Teaching Hospital

scholarly journals 1211. Microbiologic Evaluation of Mobile Phones and Hands of Healthcare Professionals in Two Intensive Care Units in a Brazilian University Hospital

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S435-S435
Author(s):  
Evelyn Patricia Sanchez Espinoza ◽  
Lauro Viera Perdigão Neto ◽  
Sania Alves dos Santos ◽  
Camila Risek ◽  
Maria Renata Gomes Franco ◽  
...  
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Mobile Phones ◽  
Bacterial Colonization ◽  
Healthcare Setting ◽  
University Hospital ◽  
High Rate ◽  
High Morbidity ◽  
Dominant Hand ◽  
Cross Sectional

Abstract Background Healthcare-associated infections (HAIs) are a worldwide concern because of their high morbidity, mortality, and associated costs. Mobile phones (MP) are an important work tool in the healthcare setting, but they can be a reservoir of nosocomial pathogens if not carefully cleaned and cause re-contamination of the healthcare professional’s (HCP) hands. We aimed to evaluate bacterial colonization of HCP’s hands and their respective MPs. Methods A cross-sectional study was performed in two Intensive Care Units (ICUs), an internal medicine and a burn unit, of a Brazilian tertiary university hospital. These units were chosen because of their different hand hygiene (HH) compliance. We assessed HH and MP handling practices by an electronic inquiry and collected samples from the dominant hand (DH) by the sterile bag technique and of MPs by moistened sterile swab. MALDI-TOF was used for bacterial identification and Dilution Agar (DA) was used to screen Gram-negative bacteria (GNB) susceptibility to carbapenems and colistin. Results Forty-seven HCPs were evaluated; of whom, 30% were medical residents, 19% nurses, 17% nurse-technicians, 17% physiotherapists, 13% cleaning staff, and 4% radiology technicians.Overall, 85% of HCPs reported use of MP at work, 26% had never cleaned it, and 34% reported optimal HH compliance practices. All of them believed that MPs can have HAIs agents. DH culture showed 94% of colonization and the most common Gram-positive bacteria (GPB) and GNB were S. epidermidis (n = 17∕44) and A. baumannii complex (n = 11∕44), respectively. MP were colonized in 89% of the cases and the most common GPB and GNB were S. epidermidis (n = 16∕42) and Pseudomonas spp (n = 9∕42), respectively. Overall, in the screening 38% of GNB were resistant to meropenem and 22% to colistin. A. baumannii was the most common meropenem (n = 4) and colistin (n = 2) resistant GNB. In the two units, 32% of HCPs had the same microorganism species isolated in the MP and in the DH (Table 1). Conclusion There was a high rate of bacterial colonization on the MP and DH of HCPs and some of these bacteria were carbapenem or colistin resistant. A policy for MP handling in the healthcare setting should be implemented in order to avoid cross-contamination between the MP and the hand of HCPs. Disclosures All authors: No reported disclosures.

Drug Utilization in Very Premature Infants in Neonatal Intensive Care Units

1991 ◽  
Vol 17 (3-4) ◽  
pp. 167-171 ◽  
Author(s):  
L. Gortner ◽  
U. Bernsau ◽  
M. Brand ◽  
H.H. Hellwege ◽  
G. Hieronimie ◽  
...  
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Drug Utilization ◽  
Premature Infants ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Very Premature Infants
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