scholarly journals New treatment of hepatitis C (Direct Acting Antiviral)

Author(s):  
Mohsen Akhondi-Meybodi

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for the patients with HCV-related liver disease has advanced considerably thanks to an enhanced understanding of the pathophysiology of the disease, and because of developments in diagnostic procedures and improvements in therapy and prevention, recently in Iran new drug direct Acting agent (DAA) was developed that may be equivalent to original drugs that will hope to treat  HCV and eliminated HCV in future

2019 ◽  
Vol 71 (2) ◽  
pp. 281-288 ◽  
Author(s):  
Maryam Alavi ◽  
Matthew G. Law ◽  
Heather Valerio ◽  
Jason Grebely ◽  
Janaki Amin ◽  
...  

2021 ◽  
Vol 17 (28) ◽  
pp. 54-60
Author(s):  
A.O. Bueverov ◽  
◽  
P.O. Bogomolov ◽  
V.E. Syutkin ◽  
◽  
...  

Hepatocellular cancer (HCC) usually develops against the background of chronic liver disease. Until recently, the most common etiology of HCC was infection with hepatitis C virus (HCV). The appearance of direct-acting antiviral drugs (DAAD) has become a big breakthrough in the treatment of HCV infection. A stable virological response can now be achieved in almost all treated patients, even in people at high risk of HCC, primarily with cirrhosis of the liver. At the same time, reports gradually began to accumulate about the continued risk of malignant transformation after successful therapy of DAAD. Simultaneously with the decrease in the burden of cirrhosis caused by HCV, the etiological role of non-alcoholic fatty liver disease (NAFLD) has sharply increased. Moreover, in a significant part of patients with NAFLD, HCC is formed at the pre-cirrhotic stage. These changes in the etiology and epidemiology of HCC suggest the revision of patient management tactics


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