scholarly journals Adverse Drug Reaction Monitoring in Chronic Obstructive Pulmonary Disease Patients in a Tertiary Care Centre

2017 ◽  
Vol 05 (04) ◽  
pp. 19884-19889
Author(s):  
Sangeetha Purushothaman ◽  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Reaction Monitoring ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Obstructive Pulmonary Disease ◽  
Adverse Drug Reaction Monitoring

scholarly journals Assessment of depression among chronic obstructive pulmonary disease (COPD) patients at rural tertiary care centre of Northern India

2017 ◽  
Vol 5 (9) ◽  
pp. 4017
Author(s):  
Aditya Kumar Gautam ◽  
Adesh Kumar ◽  
Ashish Kumar Gupta ◽  
Bal Krishna Kushwaha ◽  
Prashant Yadav ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients

Background: Chronic obstructive pulmonary disease COPD is a more complex systemic disease that has significant extra pulmonary effects along with pulmonary involvement. Complexity and mortality of COPD is increased by its co-morbidities and exacerbations. Depression is One of the commonest co-morbidity that occurs in patient with COPD and is associated with poor quality of life therefore we planned to assess depression among COPD patients.Methods: This was a cross-sectional study done in the respiratory medicine department of tertiary care centre, during the period from January 2015 to June 2016. A total of 200 patients of COPD of either sex having age more than 40 years included in the study. Patients who were critically ill and uncooperative excluded from the study. Patients who did not give consent and having previous history of any psychiatric illness also excluded from the study. The diagnosis of COPD was made on the basis of the clinical history, examination, X-ray chest and spirometry. Further, depression was evaluated with the validated Hindi version of nine items PHQ-9 (a subset of patient health questionnaire).Results: The data of all 200 COPD patients were analysed and it was observed that- prevalence of depression in COPD was found to be 49%. Prevalence was higher in male patients 147 (73.5%) as compared to female 53 (26.5%) patients in the present study. Minimal depression was found in 14.28 % COPD patients and mild depression in 25.51 % moderate depression in 39.79 % cases and severe depression in 20.40% cases.Conclusions: Symptoms of depression are common in patients with COPD and its presence may have significant impact on the quality of life of such patients and may be associated with a higher mortality rate.

scholarly journals Knowledge, attitude and practice toward adverse drug reaction reporting among practicing clinicians at a tertiary care hospital

2017 ◽  
Vol 6 (4) ◽  
pp. 845
Author(s):  
Toshan L. Todar ◽  
Manju Agrawal ◽  
Rajesh Hishikar ◽  
Anuja Jha ◽  
Basant Maheshwari ◽  
...  
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Tertiary Care ◽  
Reaction Monitoring ◽  
Adverse Drug Reaction Monitoring ◽  
Medical College ◽  
Monitoring Centre ◽  
Adr Reporting ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice

Background: Pharmacovigilance has evolved as an important tool for dealing with Adverse Drug Reactions (ADRs) both in pre-marketing and post-marketing scenario. Underreporting of ADRs at our Adverse drug reaction Monitoring Centre (AMC) led us to conduct this study to assess Knowledge, Attitude and Practice (KAP) of the practicing clinicians at our tertiary care Pt. J.N.M. Medical College associated Dr. B.R.A.M. Hospital, Raipur, Chhattisgarh, India, towards ADRs reporting.Methods: This was a cross-sectional study using pretested questionnaires consisting of 29 questions related to KAP of the practicing clinicians at Pt. J.N.M. Medical College associated Dr. B.R.A.M.  Hospital, Raipur towards ADRs reporting. The percentage of responders for each question was calculated. All statistical analysis was performed in Microsoft Office Excel 2007.Results: Out of 135 questionnaires distributed only 100 were considered for analysis, so the overall response rate was 74.07%. We calculated the result from the 100 responders. Overall 77% responders were aware of existence of ADR monitoring system in India, while only 40% were aware of its existence at their hospital. Only 8% responders had reported ADRs to the National Pharmacovigilance Centre and 10% to the Adverse drug reaction Monitoring Centre (AMC) at their hospital. Lack of knowledge about where, how and whom to report ADRs, lack of time, inability to decide what to report (known or unknown ADRs) and unavailability of ADR reporting form were the important factors discouraging them reporting ADRs.Conclusions: Creating awareness regarding ADR reporting through CMEs among practicing clinicians and early sensitization at medical undergraduate level for medical students may improve the current ADR reporting rate.  

scholarly journals A Retrospective Descriptive Study of Adverse Drug Reaction Monitoring in Tertiary Care Hospital

2020 ◽  
Vol 3 (2) ◽  
pp. 54-58
Author(s):  
Ajay K Gupta
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
System Organ Class ◽  
Therapeutic Effects ◽  
Care Hospital ◽  
Reaction Monitoring ◽  
Adverse Drug Reaction Monitoring

ABSTRACT Introduction An adverse drug reaction (ADR) is any undesirable effect of a drug to the patient beyond its anticipated therapeutic effects while used clinically. Aims and objective To analyze the incidence of ADRs in a tertiary care hospital reported from April 2015 till December 2017. Materials and methods Two hundred ADR forms were included in the study and analyzed. These were codified into various drug classes according to anatomical therapeutic chemical (ATC) classification based on WHO–ATC Index 2019 besides categorized into preventable or not modified Schumock and Thornton scale. Severity was assessed based on a scale by Hartwig et al. Also, the ADRs were classified based on MedDRA 13.01 to system organ class (SOC) and preferred terms (PT) falling under respective SOC. Results Maximum ADRs were reported by dermatology. Most commonly, it involved gastrointestinal system (GIT) followed by skin. Antibiotics and anti-cancer drugs caused maximum ADRs. About two-thirds were classifiable as moderate to severe, whereas about one-third were preventable. About 10% of cases were such that left deep impact of sequelae or were not recovered and one case was fatal. Conclusion Extreme vigilance by clinicians is of utmost crucial virtue in detecting, diagnosing, and reporting such ADR for continued drug safety monitoring. How to cite this article Gupta AK. A Retrospective Descriptive Study of Adverse Drug Reaction Monitoring in Tertiary Care Hospital. J Med Acad 2020;3(2):54–58.

Sign in / Sign up

Export Citation Format

Share Document