scholarly journals An Analysis of the Pharmacological Management of Respiratory Tract Infections in-Patients at a Tertiary Care Teaching Hospital

Author(s):  
Dr Paramita Pal ◽  
Author(s):  
Vandana Badar ◽  
Vidisha Parulekar ◽  
Priti Garate

Objectives: The objectives of the study were as follows: (1) To study the prescription patterns in Respiratory tract infections (RTI) in indoor patients in pediatric wards. (2) To check the rationality of treatment according to Modified Kunin’s rationality criteria. (3)To analyze the data of RTI by Anatomical Therapeutic Chemical classification.Methods: It was a non-interventional, prospective, observational study which was conducted in indoor pediatric patients in a tertiary care teaching hospital in India. Data were analyzed and evaluated according to the WHO rational use of drugs guidelines.Study sample: The study sample was 174.Study duration: The study duration was August 15, 2016–September 15, 2016.Results: Males (63.79%) were more as compared to females (36.20%), and the highest number of cases was seen in infants (62.06%). Acute bronchiolitis (54.02%) was highest in the incidence followed by Wheeze Associated Lower Respiratory Tract Infection (WALRI) (30.45%). The average duration of patient stay in hospital was 4.71 days whereas 93.33% were polytherapy and mostly prescribed antibiotic was amoxicillin-clavulanic acid in acute bronchiolitis and WALRI. Salbutamol (40.84%) and Ipratropium Bromide (39.43%) were the commonly prescribed respiratory medicines. Oral route (42.27%) was the most common route of administration. 56.11% drugs were prescribed by generic name.Conclusion: Standard treatment guidelines for the treatment of RTI need to be urgently developed and strictly implemented.


2021 ◽  
Vol 8 (11) ◽  
pp. 1828
Author(s):  
Rajasekar N. ◽  
Kireesh Kumar M. ◽  
Sowndarya M. ◽  
Dhanapal C. K. ◽  
Ramanathan R.

Background: Respiratory tract infections (RTI) are more common in pediatrics. Especially in developing countries like India, RTI causes more death in children. Antibiotics are used to treat RTI even in case of viral infections. Hence rational use of antibiotics is very much needed to avoid antibiotic resistance. In this study we have analysed the prescribing pattern of antibiotics and their drug interactions involved in the management of respiratory tract infections in a tertiary care teaching hospital.Methods: A prospective observational study was conducted in the department of pediatrics at a tertiary care teaching hospital for a period of 6 months (November 2019-April 2020). A total of 144 patients were included in the study and their prescription was analysed for their antibiotic prescribing pattern and interactions.Results: Infants were more prone to RTI infections. Among RTI, lower RTI were more common in children. We have analysed prescribing pattern of antibiotics in which, mono antibiotic therapy were more commonly used. Ampicillin was the frequently prescribed antibiotic. Azithromycin had the most possible interactions among the antibiotics prescribed.Conclusions: More than 336 antibiotics were used for all types of RTI, even in the case of viral infections. So rational use of antibiotics is needed. Among 144 children who were enrolled in the study, none of them were subjected to culture sensitivity test. As of which, all of them were treated empirically. Penicillin and cephalosporin are the mostly prescribed antibiotics in RTI. Cephalosporin prescribed children had less hospital stay and hardly interactions were found.


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