scholarly journals Laboratory Risk Indicator in Necrotizing Fasciitis (LRINEC) Score- An Early Diagnostic Tool for Necrotizing Fasciitis

2019 ◽  
Vol 7 (7) ◽  
Author(s):  
Dr Snigdh Garg ◽  
Keyword(s):  
Necrotizing Fasciitis ◽  
Diagnostic Tool ◽  
Risk Indicator ◽  
Lrinec Score ◽  
Early Diagnostic

scholarly journals Prospective Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for Necrotizing Fasciitis of the Extremities

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227748 ◽  
Author(s):  
Cheng-Ting Hsiao ◽  
Chia-Peng Chang ◽  
Tsung-Yu Huang ◽  
Yi-Chuan Chen ◽  
Wen-Chih Fann
Keyword(s):  
Necrotizing Fasciitis ◽  
Risk Indicator ◽  
Lrinec Score

scholarly journals Necrotizing fasciitis with prior leprosy: a case report

2020 ◽  
Vol 6 (6) ◽  
pp. 788
Author(s):  
Vannia C. Teng ◽  
Prima K. Esti ◽  
Sweety Pribadi
Keyword(s):  
Case Report ◽  
Necrotizing Fasciitis ◽  
Limited Resource ◽  
Masking Effect ◽  
Risk Indicator ◽  
Broad Spectrum Antibiotic ◽  
Life Threatening ◽  
Lrinec Score ◽  
Improve Patient Management ◽  
Improve Patient

<p class="abstract">Necrotizing fasciitis (NF) is a life-threatening soft tissue infection with a high misdiagnosis rate. Here, we present the case of NF with hypoesthesia due to prior leprosy in a limited resource area. Laboratory risk indicator for NF (LRINEC) score was used to determine the diagnosis of NF. Resuscitation and broad-spectrum antibiotic were initiated, followed by surgical debridement due to lack of wound improvement and skin graft to cover the wound was done. This case report highlights the usage of LRINEC score to reduce misdiagnosis, ensure early diagnosis, and improve patient management in NF with masking effect.</p>

Usefulness of serum procalcitonin for necrotizing fasciitis as an early diagnostic tool

2021 ◽  
Author(s):  
Takaaki Kishino ◽  
Nobuhiro Asai ◽  
Wataru Ohashi ◽  
Daisuke Sakanashi ◽  
Hideo Kato ◽  
...  
Keyword(s):  
Necrotizing Fasciitis ◽  
Diagnostic Tool ◽  
Early Diagnostic

scholarly journals Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for the Head and Neck Region

2019 ◽  
Vol 122 (6) ◽  
pp. 884-890
Author(s):  
Chie Ishikawa ◽  
Takao Hamamoto ◽  
Takashi Ishino ◽  
Tsutomu Ueda ◽  
Sachio Takeno
Keyword(s):  
Necrotizing Fasciitis ◽  
Head And Neck ◽  
Neck Region ◽  
Risk Indicator ◽  
Head And Neck Region ◽  
Lrinec Score

scholarly journals A retrospective case series of Fournier’s gangrene: necrotizing fasciitis in perineum and perianal region

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Nan Zhang ◽  
Xin Yu ◽  
Kai Zhang ◽  
Tongjun Liu
Keyword(s):  
Necrotizing Fasciitis ◽  
Case Series ◽  
Fournier’S Gangrene ◽  
Wound Management ◽  
Risk Indicator ◽  
Fournier's Gangrene ◽  
Retrospective Case ◽  
Female Ratio ◽  
Male Predominance ◽  
Lrinec Score

Abstract Background To describe the clinical characteristics and management for Fournier’s gangrene. Experience summary and literature references are provided for future treatment improvement. Methods We retrospectively reviewed the cases diagnosed with Fournier’s gangrene in our department from June 2016 to June 2019. Clinical data, including manifestation, diagnosis, treatment and outcomes for Fournier’s gangrene were presented. Results There were 12 patients enrolled in this paper, with the average age of 60 years old. It showed a male predominance with male-to-female ratio of 6:1. The average of laboratory risk indicator for necrotizing fasciitis (LRINEC) score was 10.1. Diabetes mellitus was the main predisposing disease. 11 patients received emergency debridement and 1 patient died of sepsis on the 2nd day after admission. The mortality rate was 8.3%. 6 cases developed complications, including sepsis, pneumonia, renal and heart failure. Negative pressure wound therapy (NPWT) was applied in 10 cases, while the rest 1 received normal daily dressing changes because of fecal contamination. Flaps were utilized in 2 patients to cover the defect, including one with advancement flap and one with pudendal-thigh flap, while others received secondary suture, secondary healing, skin graft or combined management. No relapse was observed during the follow-up visits. Conclusions Fournier’s gangrene is a life-threatening infection that requires early diagnosis and surgery intervention. The predisposing disease, clinical manifestation and LRINEC score should be taken into comprehensive consideration, which is helpful for timely diagnosis. Moreover, further successful treatment depends on the aggressive debridement, broad-spectrum antibiotics therapy, wound management and closure choice.

scholarly journals The characteristics of oro-cervical necrotizing fasciitis—Comparison with severe cellulitis of oro-cervical region and necrotizing fasciitis of other body regions

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260740
Author(s):  
Eiji Iwata ◽  
Junya Kusumoto ◽  
Naoki Takata ◽  
Shungo Furudoi ◽  
Akira Tachibana ◽  
...  
Keyword(s):  
Necrotizing Fasciitis ◽  
Inflammatory Markers ◽  
Multivariate Analyses ◽  
Clinical Stage ◽  
Severe Infection ◽  
Clinical Findings ◽  
Cervical Region ◽  
Risk Indicator ◽  
Body Regions ◽  
Lrinec Score

Background Necrotizing fasciitis (NF) is an acute and life-threatening soft-tissue infection however rarely seen in oro-cervical region. Therefore, the details of oro-cervical NF (OCNF) are not well known. The purpose of this study was to investigate the characteristics of OCNF by comparing it with severe cellulitis of oro-cervical region (OCSC) or NF of other body regions (e.g., limb, perineum, and trunk) (BNF), respectively. Materials and methods At first, various risk factors for OCNF in oro-cervical severe infection (OCSI; composed of OCNF and OCSC), including neutrophil-to-lymphocyte ratio (NLR) and Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score, were investigated by univariate and multivariate analyses. Next, the differences between OCNF and BNF, including inflammatory markers and mortality, were investigated. Results In the present study, 14 out of 231 OCSI patients had OCNF. Multivariate analyses of OCSI patients showed that NLR ≥15.3 and LRINEC score ≥6 points were significantly related to OCNF. During the same period, 17 patients had BNF. The OCNF group had significantly higher inflammatory markers than the BNF group when diagnosis, but significantly lower clinical stages at the time and mortality as outcomes. Conclusion We found that compared to BNF, OCNF can be detected at lower clinical stage by using indexes, such as NLR and LRINEC score, besides clinical findings, which may help contributing to patient’s relief.

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