Clinical and laboratory evaluation of the effectiveness of a personified approach to treating bacterial vaginosis and its concurrence with vulvovaginal candidiasis

2020 ◽  
Vol 3_2020 ◽  
pp. 198-202
Author(s):  
Pestrikova T.Yu. Pestrikova ◽  
Yurasova E.A. Yurasova ◽  
Kotelnikova A.V. Kotelnikova ◽  
Strelnikova N.V. Strelnikova N ◽  
Voronova Yu.V. Voronova ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Vulvovaginal Candidiasis ◽  
Laboratory Evaluation

Laboratory evaluation of the etiology of pathological vaginal dischurge

2019 ◽  
pp. 64-68
Author(s):  
O.A. Burka ◽  
◽  
T.M. Tutchenko ◽  
Keyword(s):  
Bacterial Vaginosis ◽  
Crucial Role ◽  
Inflammatory Process ◽  
Vaginal Discharge ◽  
Vulvovaginal Candidiasis ◽  
Diagnostic Methods ◽  
Laboratory Evaluation ◽  
Aerobic Vaginitis ◽  
Laboratory Confirmation ◽  
Vaginal Secretions

Pathological vaginal discharge is one of the most common complaints in women of all ages. Today, gynecologists are increasingly faced with a problem when, in the absence of laboratory confirmation of vulvovaginal candidiasis, bacterial vaginosis and STIs, women complain of discomfort caused by vaginal secretions. Causes of pathological vaginal discharge can be infectious and non-infectious processes and their combinations. The article analyzes the causes of the difficulties of diagnosing the of pathological vaginal discharge ethiology, demonstrates how the application of adequate volume of modern laboratory diagnostic methods in combination with understanding the multifaceted components of the inflammatory process plays crucial role in finding out the etiology of pathological vaginal secretions and the choice of optimal therapeutic tactics. Key words: pathological vaginal dischurge, vaginal microbiota, vulvovaginal candidiasis, bacterial vaginosis, aerobic vaginitis, cytolytic vaginosis.

The efficacy and safety of using the topical medicine with combined action in patients with opportunistic vaginal infections

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. 22-26
Author(s):  
Vera N. Prilepskaya ◽  
Giuldana R. Bairamova ◽  
Elena A. Mezhevitinova ◽  
Andrei E. Donnikov ◽  
Dmitry Yu. Trofimov ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Genital Tract ◽  
Clinical Signs ◽  
Vulvovaginal Candidiasis ◽  
Long Term Results ◽  
Vaginal Infections ◽  
Aerobic Vaginitis ◽  
Laboratory Parameters ◽  
Recommended Treatment ◽  
Gynecological Examination

Relevance.Infections of the lower genital tract are one of the most common reasons for women to visit a gynecologist. According to various authors, among all vulvovaginitis, the highest percentage of patients visiting a doctor is bacterial vaginosis (2050%), vulvovaginal candidiasis (1739%), trichomoniasis (10%) and other genital infections (10%). In the management of patients with infectious processes of the genitals, the choice of the method of therapy is of great importance, which allows not only to influence the microbes-associates, detected in high concentrations in the womans vagina during the initial episode of the disease, but also to prevent the development of relapses. Aim.To evaluate the clinical and laboratory efficacy, adherence and long-term results of benzydamine use in patients with vulvovaginal candidiasis, aerobic vaginitis and bacterial vaginosis Materials and methods.The study included 31 women aged 18 to 49 years, who complained of abundant discharge from the genital tract, itching, burning, dyspareunia. A comprehensive clinical and laboratory examination was carried out, including the collection of anamnestic data, general and special gynecological examination, microscopy of vaginal smears, KOH test, determination of the pH of the vaginal environment, assessment of vaginal microbiocenosis by quantitative PCR in real time. All patients were prescribed benzydamine hydrochloride, which was used as monotherapy in the form of a vaginal solution according to the recommended treatment regimen specified in the instructions for medical use of the drug TantumRosa 1 (irrigation 2 times a day for 10 days). Results.In 1219 days after beginning treatment, 25 (80.6%) of 31 patients with laboratory signs of vaginal microflora alterations showed restoration of the normal vaginal biocenosis laboratory parameters. Of them, 8 patients initially had dysbiosis, 12 patients yeast-like fungi, 4 patients aerobic vaginitis and 1 patient a combination of dysbiosis and fungi. Herewith, all patients also noted clinical signs of improvement. In 1219 days after beginning treatment, 6 (1.4%) of 31 patients with laboratory signs of vaginal biocenosis alterations had unsatisfactory laboratory parameters; that is vaginal biocenosis alterations (a decrease in Lactobacillus spp. percentage). At the same time, there were no clinical signs of pronounced inflammation such as pathological discharge, hyperemia, vaginal swelling. Conclusion.Benzydamine hydrochloride can be widely used in gynecological practice due to its combined effects on inflammation of the vagina, good clinical and microbiological results. It is important to note that additional therapy with drugs which contain lactobacilli is required only in 19.4% of cases. The clinical and laboratory effectiveness of benzydamine hydrochloride (TantumRosa) was 96.8%, since the relapse rate after 3060 days of the study did not exceed 3.2%.

scholarly journals Cliniciansʼ Use of Intravaginal Boric Acid Maintenance Therapy for Recurrent Vulvovaginal Candidiasis and Bacterial Vaginosis

2019 ◽  
Vol 46 (12) ◽  
pp. 810-812
Author(s):  
Anna Powell ◽  
Khalil G. Ghanem ◽  
Linda Rogers ◽  
Ashley Zinalabedini ◽  
Rebecca M. Brotman ◽  
...  
Keyword(s):  
Maintenance Therapy ◽  
Boric Acid ◽  
Bacterial Vaginosis ◽  
Vulvovaginal Candidiasis ◽  
Recurrent Vulvovaginal Candidiasis

scholarly journals Role of probiotics in lower reproductive tract infection in women of age group 18 to 45 years

2017 ◽  
Vol 6 (2) ◽  
pp. 671
Author(s):  
Rukshana Shamshu ◽  
Jayasree Vaman ◽  
Nirmala C.
Keyword(s):  
Bacterial Vaginosis ◽  
Lactobacillus Reuteri ◽  
Lactobacillus Rhamnosus ◽  
Vulvovaginal Candidiasis ◽  
Controlled Study ◽  
Control Group ◽  
P Value ◽  
Double Blind ◽  
Reproductive Tract Infection ◽  
Conventional Antibiotics

Background: This study has been designed to assess the effectiveness of the probiotic strains having Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in the management of lower genital infections (bacterial vaginosis and candidiasis) as an integral therapy with antibiotics.Methods: Double blind, randomized placebo controlled study in women between 18-45 years attending Sree Avittom Thirunal Hospital (SATH), Government Medical College, Thiruvananthapuram, India with symptoms of bacterial vaginosis and vulvovaginal candidiasis. Women giving consent were given probiotics along with conventional antibiotics and were followed up over a period of two months. Outcome is measured as percentage of women showing a score of less than 4 at the end of thirty days of treatment, and sixty days of treatment in the test and control group in the case of bacterial vaginosis and no discharge and absence of hyphae and pseudohyphae in wet smear and gram stain in case of candidiasis.Results: Out of 42 women studied, 32 had bacterial vaginosis and 10 had vulvovaginal candidiasis. 81.3% women with BV had a normal vaginal picture after sixty days of treatment as compared to placebo which was only 31.3%. The p value is 0.004 which is significant. In the treatment of VC, the percentage of women cured was the same in both probiotic and placebo group.Conclusions: In the treatment of bacterial vaginosis, addition of probiotics to the conventional antibiotics can improve the cure rate of bacterial vaginosis and reduce the rate of recurrences. In the treatment of vulvovaginal candidiasis, addition of probiotics to the conventional antifungal did not have a significant improvement.

Modern opportunities of effective combined treatment of vulvovaginal candidiasis and bacterial vaginosis

2018 ◽  
Vol 17 (4) ◽  
pp. 65
Author(s):  
V. S. Dmitruk ◽  
A. A. Denisov ◽  
P. A. Lushnikova
Keyword(s):  
Bacterial Vaginosis ◽  
Combined Treatment ◽  
Vulvovaginal Candidiasis

Prevalence of Bacterial Vaginosis and Vulvovaginal Candidiasis Mixed Infection in a Southeastern American STD Clinic

2011 ◽  
Vol 38 (7) ◽  
pp. 672-674 ◽  
Author(s):  
Charles A. Rivers ◽  
Oluwaseun O. Adaramola ◽  
Jane R. Schwebke
Keyword(s):  
Bacterial Vaginosis ◽  
Mixed Infection ◽  
Vulvovaginal Candidiasis

Lactic acid bacteria colonization and clinical outcome after probiotic supplementation in conventionally treated bacterial vaginosis and vulvovaginal candidiasis

2010 ◽  
Vol 12 (10) ◽  
pp. 691-699 ◽  
Author(s):  
Sophia Ehrström ◽  
Katalin Daroczy ◽  
Eva Rylander ◽  
Carolina Samuelsson ◽  
Ulrika Johannesson ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Clinical Outcome ◽  
Bacterial Vaginosis ◽  
Vulvovaginal Candidiasis ◽  
Probiotic Supplementation
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