Features of the epidemic process of chronic hepatitis B in the Russian Federation and the Samara Region

Author(s):  
Churbakova O.V. Churbakova ◽  
Akimkin V.G. Akimkin ◽  
Pechkurov D.V. Pechkurov ◽  
◽  
Author(s):  
Churbakova O.V. Churbakova ◽  
Akimkin V.G. Akimkin ◽  
Pechkurov D.V. Pechkurov ◽  
◽  

2019 ◽  
Vol 96 (6) ◽  
pp. 508-515
Author(s):  
Svetlana V. Baramzina

In Russia and the Kirov region (KR) there was a tendency to the reduction of the incidence rate of chronic hepatitis B (CHB) in adults due to vaccine prevention. Objective is to study the impact of the additional vaccination of adults from HBV-infection in 2007-2014 on the incidence rate of chronic hepatitis B on the example of the Kirov region; to assess the level of awareness of the “naive” population concerning epidemiology, outcomes and vaccine prevention of hepatitis B in the total group and in dependence on the age. Material and Methods. We treated data of Federal Supervision Service for Consumer’s Rights Protection and Human Welfare in the Russian Federation and KR on infectious diseases for the period of 1999-2014; State report on sanitary and epidemiological situation in the Russian Federation for 1998-2014, in the KR - for 2006-2014. With the help of the original questionnaire 850 persons aged of from 16 to 80 years, resided in the city of Kirov and the Kirov region, were interviewed anonymously, in 2013-15. Out of them for the comparison there were selected 2 groups: Group 1: cases aged of 18-35 years; Group 2: persons aged of 36-59 years. Results. The reason for the slow decrease in the incidence rate of chronic hepatitis B may be poor (20.3-64%) adult immunization coverage in 2007-2012. Poll “naive” adults revealed insufficient knowledge of epidemiology and outcomes of chronic hepatitis B, a good - questions vaccination of hepatitis B (81.8%). The survey of “naive” adults revealed the level of knowledge of the epidemiology and outcomes of HBV to be insufficient, the level concerning questions of vaccine prophylaxis for HBV to be good (81.8%). Awareness of HBV-infection depended on the age. Participants from the 2nd group had higher levels of general education. They knew ways of hepatitis B virus transmission significantly better but less about adverse outcomes of hepatitis B (11.0% cases) if compared with those of group 1, they showed more negative attitude to vaccination (30.8%) and failed to anticipate the possibility of antiviral therapy of Hepatitis B (27.7%). Conclusion. The lack of awareness on the epidemiology and outcomes of hepatitis B can be one of the reasons for the refusal of vaccination in persons aged of 36-59 years. The medical community must actualize the problem of HBV-infection for promotion of immunization coverage and achieving of inoculations coverage up to 80-90%.


Author(s):  
Anastasia Fomicheva ◽  
Nikolay Pimenov ◽  
Svetlana Komarova ◽  
Aleksandr Urtikov ◽  
Olga Paevskaya ◽  
...  

Aim. To determine the epidemiological features of the hepatitis B in the Russian Arctic. Materials and methods. We carried out a retrospective analysis of the incidence of hepatitis B (acute and chronic forms) in 9 Russian Arctic regions, 3 subarctic regions (Khanty-Mansiysk Autonomous Okrug, Magadan Region, Kamchatka Territory) and Russian Federation in 1999-2019. We also studied the prevalence of chronic hepatitis B and vaccination data against hepatitis B in these territories. Results. From 1999 to 2019 the incidence of acute hepatitis B in three subarctic regions decreased 166 times (from 66.5 to 0.4 per 100 thousand population), in the Arctic zone of 73 times (from 29.8 to 0.4 per 100 thousand population) and 77 times in Russia (from 43.8 to 0.6). The incidence of chronic hepatitis forms in the same period in the Arctic zone decreased by 16.3 times (from 140.1 to 16.3), 5.8 times in the subarctic regions (from 116.6 to 20.0) and 5.7 times in Russia (from 96.3 to 16.8). In 2018, the results of the prevalence of chronic hepatitis B in the Arctic zone (697.3) was higher than in Russia by 98% (352.1) and higher than in the subarctic regions by 67% (588.6). Timely coverage of hepatitis vaccination in children aged 12 months in the Russian Federation, the Arctic zone and the subarctic regions is maintained at a high level (more than 90%) from 2004 in 2019. Coverage of children by vaccination to 17 years inclusive and adults up to 35 years on these territories also exceeded 90%. Conclusion. Vaccination against hepatitis B in the Russian Federation led to a significant decrease in the incidence of this infection in the Russian Arctic. High prevalence of infection indicates the need to continue the program of mass vaccination and the timely introduction of the first dose of vaccine newborns. To reduce the risk of cirrhosis and liver cancer, it is necessary to increase the availability of diagnosis of the disease and its possible outcomes in the Arctic regions and timely provision of antiviral treatment of all patients.


Author(s):  
Elena A. Galova

The article presents the results of analysis of reported incidence of chronic hepatitis B and chronic hepatitis С in children of Nizhny Novgorod region in 2000-2015. Description of epidemiology of chronic hepatitis B and chronic hepatitis С in children in different age groups is provided. Distinction of the incidence of chronic hepatitis B and chronic hepatitis С in children indicate about different mechanisms of the epidemic process of disease and determine the need to develop age-appropriate approach to their prevention.


2001 ◽  
Vol 120 (5) ◽  
pp. A572-A572
Author(s):  
P LAMPERTICO ◽  
M VIGANO ◽  
M LAVARONE ◽  
E DELNINNO ◽  
M COLOMBO

2005 ◽  
Vol 36 (5) ◽  
pp. 50-51
Author(s):  
ELIZABETH MECHCATIE

2007 ◽  
Vol 40 (15) ◽  
pp. 32
Author(s):  
WILLIAM E. GOLDEN ◽  
ROBERT H. HOPKINS

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