scholarly journals Peripheral blood lymphocyte subset levels differ in patients with hepatocellular carcinoma

Oncotarget ◽  
2016 ◽  
Vol 7 (47) ◽  
pp. 77558-77564 ◽  
Author(s):  
Hai-Zhou Liu ◽  
Wei Deng ◽  
Ji-Lin Li ◽  
Ya-Mei Tang ◽  
Li-Tu Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Lymphocyte Subset ◽  
Peripheral Blood Lymphocyte Subset

Dynamic Changes in Serum Cortisol and Acth Levels and Lymphocyte Subset Counts in Children With Septic Shock

2020 ◽  
Author(s):  
Min Lin ◽  
Bo-Qiu Zhang ◽  
Hai Lin ◽  
Peng-Ming Sun ◽  
Shi-Biao Wang ◽  
...  
Keyword(s):  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Early Stage ◽  
Serum Cortisol ◽  
Lymphocyte Subset ◽  
Advanced Stage ◽  
Dynamic Changes ◽  
Significant Difference ◽  
Peripheral Blood Lymphocyte Subset

Abstract Backgroud: To study the dynamic changes in serum cortisol, adrenocorticotropic hormone (ACTH) levels and peripheral blood lymphocyte subset counts in children with septic shock (SS) and to explore their association with the severity and prognosis of the disease. Methods: The levels of serum cortisol, ACTH and peripheral blood lymphocyte subsets were analyzed in 25 patients in the advanced-stage group with decreased blood pressure and 24 patients in the early-stage group with normal blood pressure. Twenty-five healthy children who underwent physical examination were selected as the control group. Children in the advanced-stage group were further divided into the death subgroup (n = 5) and the survival subgroup (n = 20).Results: At admission, the levels of serum cortisol and ACTH in the advanced-stage group were apparently higher than those in the early-stage group (P < 0.05). The advanced-stage group had significantly lower lymphocyte subset counts than the early-stage group (P < 0.05). On the 3rd day after admission, the levels of serum cortisol and ACTH in both groups decreased, and the counts of total lymphocytes, T cells and Th cells in the early-stage group were significantly higher than those at admission. On the 8th day after admission, there was no statistically significant difference in the levels of serum cortisol or ACTH between the groups. At admission, there was no statistically significant difference in serum cortisol and ACTH levels between the death subgroup and the survival subgroup. On the third day after admission, the levels of cortisol and ACTH were decreased in both groups, but the differences between the two subgroups were not statistically significant. All the lymphocyte subset counts in the death subgroup on the third day after admission were significantly lower than those in the survival subgroup (P < 0.05).Conclusions: The hypothalamic-pituitary-adrenal axis is excessively activated in children with SS. Higher serum cortisol and ACTH levels and lower peripheral blood lymphocyte subset counts indicate increased severity of the disease. After treatment, the first signs that indicate the effective control of the disease are decreased serum cortisol and ACTH levels and increased T cell, Th cell and total lymphocyte counts.

Changes in peripheral blood lymphocyte subset frequencies in myasthenia gravis patients are related to immunosuppression

1994 ◽  
Vol 241 (4) ◽  
pp. 218-222 ◽  
Author(s):  
Francesca Crosti ◽  
Marta Armanini ◽  
Paolo Confalonieri ◽  
Carlo Antozzi ◽  
Renato Mantegazza
Keyword(s):  
Myasthenia Gravis ◽  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Lymphocyte Subset ◽  
Peripheral Blood Lymphocyte Subset

Peripheral Blood Lymphocyte Subset Counts in Patients with Dermatomyositis

Medicine ◽  
2003 ◽  
Vol 82 (2) ◽  
pp. 82-86 ◽  
Author(s):  
Manuelle Viguier ◽  
Sébastien Fouéré ◽  
Pauline De La Salmonière ◽  
Claire Rabian ◽  
Céleste Lebbe ◽  
...  
Keyword(s):  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Lymphocyte Subset ◽  
Peripheral Blood Lymphocyte Subset

Peripheral blood lymphocyte subset repertoires are biased and reflect clinical features in patients with dermatomyositis

2018 ◽  
Vol 48 (3) ◽  
pp. 225-229 ◽  
Author(s):  
H Sasaki ◽  
A Takamura ◽  
K Kawahata ◽  
T Takashima ◽  
K Imai ◽  
...  
Keyword(s):  
Clinical Features ◽  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Lymphocyte Subset ◽  
Peripheral Blood Lymphocyte Subset

Peripheral blood lymphocyte subset shifts in patients with untreated hematological tumors: Evidence for systemic activation of the T cell compartment

1998 ◽  
Vol 22 (2) ◽  
pp. 175-184 ◽  
Author(s):  
Ludwig E. Van den Hove ◽  
Peter Vandenberghe ◽  
Stefaan W. Van Gool ◽  
Jan L. Ceuppens ◽  
Hilde Demuynck ◽  
...  
Keyword(s):  
T Cell ◽  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Lymphocyte Subset ◽  
Cell Compartment ◽  
Peripheral Blood Lymphocyte Subset ◽  
Hematological Tumors
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