scholarly journals A subgroup of pleural mesothelioma expresses ALK protein and may be targetable by combined rapamycin and crizotinib therapy

Oncotarget ◽  
2018 ◽  
Vol 9 (29) ◽  
pp. 20781-20794 ◽  
Author(s):  
Dina Mönch ◽  
Sabine Bode-Erdmann ◽  
Jörg Kalla ◽  
Jörn Sträter ◽  
Carsten Schwänen ◽  
...  
Keyword(s):  
Pleural Mesothelioma ◽  
Alk Protein

Poor nutritional status negatively influences prognosis of malignant pleural mesothelioma patients undergoing multimodal therapy

2019 ◽  
Author(s):  
O Lauk ◽  
M Hashimoto ◽  
U Held ◽  
M Friess ◽  
W Weder ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Malignant Pleural Mesothelioma ◽  
Multimodal Therapy ◽  
Pleural Mesothelioma ◽  
Poor Nutritional Status

Heart Failure due to Tension Hydrothorax after Left Pneumonectomy

2013 ◽  
Vol 16 (6) ◽  
pp. 319 ◽  
Author(s):  
Kim Maguire ◽  
Calvin Leung ◽  
Visali Kodali ◽  
Brice Taylor ◽  
Jacques-Pierre Fontaine ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Rare Complication ◽  
Right Heart Failure ◽  
Symptomatic Improvement ◽  
Extrapleural Pneumonectomy ◽  
Pleural Mesothelioma ◽  
Low Cardiac Output ◽  
Mediastinal Shift ◽  
Left Pleural Effusion

Tension hydrothorax is a rare complication of pneumonectomy for pleural mesothelioma and an exceptionally rare cause of heart failure. We describe a patient who had undergone extrapleural pneumonectomy, chemotherapy, and radiation for pleural mesothelioma and who developed heart failure symptoms within months of the completion of treatment. Investigation showed a massive left pleural effusion resulting in tension hydrothorax, mediastinal shift, and evidence of right heart failure with constrictive physiology and low cardiac output. Therapeutic thoracentesis resulted in increase in cardiac output and symptomatic improvement.

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