scholarly journals Blood pressure, lipid levels and apolipoprotein A1 and paraoxonase 1 gene polymorphisms in patients with abdominal obesity

2012 ◽  
Vol 18 (3) ◽  
pp. 255-266
Author(s):  
H. .. An-Hahar ◽  
O. O. Bolshakova ◽  
O. D. Belyaeva ◽  
O. A. Berkovich ◽  
V. I. Larionova ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Abdominal Obesity ◽  
Apolipoprotein A1 ◽  
Paraoxonase 1 ◽  
Gene Interactions ◽  
Lipid Levels ◽  
Q192r Polymorphism ◽  
High Incidence ◽  
Different Types ◽  
Design And Methods

Objective. To evaluate G-75A and C+83T polymorphisms of apolipoprotein A1 gene and Q192R polymorphism of paraoxonase 1 gene and their association with blood pressure and lipid levels in patients with abdominal obesity. Design and methods. We examined 222 obese patients (57 males and 165 females), residents of St Petersburg, Russian Federation. Results. High incidence of arterial hypertension (61 %) and dyslipidemia of different types was revealed. The frequency of different alleles of apolipoprotein A1 and paraoxonase 1 genes was analyzed. The results of gene-gene interactions and their associations with blood pressure, obesity and lipids profiles are presented.

scholarly journals Comparison of Propofol and Thiopentone Anaesthesia (with Special Reference to Recovery Characteristics)

1987 ◽  
Vol 15 (4) ◽  
pp. 389-393 ◽  
Author(s):  
W. M. Weightman ◽  
M. Zacharias
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Day Case ◽  
Early Recovery ◽  
Day Case Surgery ◽  
Pain On Injection ◽  
High Incidence ◽  
Case Surgery ◽  
Repeated Doses ◽  
The Mean

Thiopentone and propofol were used for the induction and maintenance of anaesthesia in unpremedicated patients undergoing minor gynaecological procedures. There were no significant differences in the induction and maintenance characteristics except for a high incidence of pain on injection and a greater fall in the mean systolic blood pressure associated with propofol in comparison with thiopentone. Propofol was associated with a quicker early recovery as well as a faster psychomotor recovery, as tested by a peg-board. However, complete psychomotor recovery was not achieved for up to three hours in some patients receiving propofol and so caution is advised regarding the early street fitness of patients receiving repeated doses of the drug for day case surgery.

Exposure to Chinese Famine in the Early Life, Adulthood Obesity Patterns, and the Incidence of Hypertension: A 22-Year Cohort Study

2021 ◽  
pp. 1-7
Author(s):  
Yu Wang ◽  
Jibin Jin ◽  
Yue Peng ◽  
Yongjie Chen
Keyword(s):  
Blood Pressure ◽  
Abdominal Obesity ◽  
Current Treatment ◽  
Late Childhood ◽  
Fetal Life ◽  
General Obesity ◽  
Antihypertensive Medications ◽  
Childhood Exposure ◽  
Famine Exposure ◽  
Obesity Hypertension

<b><i>Introduction:</i></b> Little is known regarding the joint associations of famine exposure and obesity patterns with the incidence of hypertension. <b><i>Methods:</i></b> We defined famine exposure cohorts as follows: nonexposure (born between 1962 and 1965), fetal life exposure (born between 1959 and 1961), early childhood exposure (born between 1956 and 1958), midchildhood exposure (born between 1953 and 1955), and late childhood exposure (born between 1949 and 1952). Obesity patterns were defined as follows: G−/A−: subjects without neither general obesity nor abdominal obesity; G+/A− or G−/A+: subjects with either general obesity or abdominal obesity; G+/A+: subjects with both general obesity and abdominal obesity. Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg or current treatment with antihypertensive medications. <b><i>Results:</i></b> There were 5,235 individuals participating in this study. In the subjects with general or abdominal obesity, famine exposure was associated with a lower risk of hypertension. In males with G−/A−, famine exposures in the midchildhood (<i>p</i> = 0.048; HR: 0.700; HR 95% CI: 0.491–0.998) and late childhood (<i>p</i> = 0.002; HR: 0.560; HR 95% CI: 0.374–0.840) were associated with a lower incidence of hypertension. <b><i>Conclusion:</i></b> The coexistence of famine exposure and obesity patterns was associated with the incidence of hypertension.

Components Analysis of Metabolic Syndrome in Acute Myocardial Infarction Patients

2018 ◽  
Vol 29 (2) ◽  
pp. 6-10
Author(s):  
Khan MMR ◽  
Sana NK ◽  
PM Basak ◽  
BC Sarker ◽  
M Akhtarul Islam ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Acute Myocardial Infarction ◽  
High Blood Pressure ◽  
Abdominal Obesity ◽  
Premature Death ◽  
Medical College ◽  
The Metabolic Syndrome ◽  
Low Hdl

Background: Metabolic syndrome confers the risk of developing acute myocardial infarction which is the most common form of coronary heart disease and the single most important cause of premature death worldwide. The frequency and association of different components of metabolic syndrome on AMI are not well understood and has not been well evaluated.Objective: The aim of this study was to assess the components of the metabolic syndrome and its association with AMI patients. This study will help in awareness building in reducing AMI by early detection of components of metabolic syndrome.Patients and methods: This was a prospective observational study consisted of 325 AMI patients who were aged >20 years. Patients with first time AMI arriving in CCU of Rajshahi medical college during the period of 2012-2014, were included. Data were collected through interview, clinical examination, and laboratory tests within 24 hrs of AMI. Five components of metabolic syndrome were defined according to criteria set by modified NCEP ATP III (according to ethnic variation).Results: In AMI patients (n=325), no metabolic components were in 24 (7.4%) patients, one in 53 (16.3%), 2 components in 91(28.0%), 3 components were in 61(18.8%), 4 in 67(20.6%) and all 5 components were in 29 (8.9%) patients. In this study, there was no component in 7.4% of AMI patients, at least 1 component was 92.6%, at least 2 components were 76.3%, at least 3 components were 48.3%, at least 4 components were 29.5% and at least 5 components were 8.9%. The Metabolic syndrome was 48.3% (n=157). Among metabolic syndrome (≥3 components) in AMI (n=157, 48.3%) 4 components (20.6%) were more, next was 3 components (18.8%) and than 5 components (8.9%). Overall frequencies of components in acute myocardial infarction (n=325) were in order of abdominal obesity (54.8%) > high blood pressure (54.5%) > high FPG (54.2%) > Triglyceride (46.2%) and low HDL-C (46.2%) in acute myocardial infarction. Highest percentage was observed in abdominal obesity (54.8%) followed by high blood pressure (54.5%) and FPG (54.2%).TAJ 2016; 29(2): 6-10

Genetic analysis of serum lipid levels and blood pressure in a large kindred

1987 ◽  
Vol 26 (3) ◽  
pp. 511-519 ◽  
Author(s):  
Mary L. Marazita ◽  
Robert C. Elston ◽  
Kadambari K. Namboodiri ◽  
Curtis G. Hames ◽  
John M. Opitz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Genetic Analysis ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

Hemorheological disturbances, metabolic parameters and blood pressure in different types of obesity

1991 ◽  
Vol 88 (1) ◽  
pp. 21-28 ◽  
Author(s):  
M WYSOCKI ◽  
M KROTKIEWSKI ◽  
M BRAIDE ◽  
U BAGGE
Keyword(s):  
Blood Pressure ◽  
Metabolic Parameters ◽  
Different Types

Evaluating complex interventions: A theory-driven realist-informed approach

Evaluation ◽  
2017 ◽  
Vol 23 (3) ◽  
pp. 294-311 ◽  
Author(s):  
Boru Douthwaite ◽  
John Mayne ◽  
Cynthia McDougall ◽  
Rodrigo Paz-Ybarnegaray
Keyword(s):  
Complex Interventions ◽  
Monitoring And Evaluation ◽  
Practical Experience ◽  
Evaluation Systems ◽  
Program Monitoring ◽  
Evaluation Approach ◽  
Different Types ◽  
Theories Of Change ◽  
Design And Methods ◽  
After Action Reviews

There is a growing recognition that programs that seek to change people’s lives are intervening in complex systems, which puts a particular set of requirements on program monitoring and evaluation. Developing complexity-aware program monitoring and evaluation systems within existing organizations is difficult because they challenge traditional orthodoxy. Little has been written about the practical experience of doing so. This article describes the development of a complexity-aware evaluation approach in the CGIAR Research Program on Aquatic Agricultural Systems. We outline the design and methods used including trend lines, panel data, after action reviews, building and testing theories of change, outcome evidencing and realist synthesis. We identify and describe a set of design principles for developing complexity-aware program monitoring and evaluation. Finally, we discuss important lessons and recommendations for other programs facing similar challenges. These include developing evaluation designs that meet both learning and accountability requirements; making evaluation a part of a program’s overall approach to achieving impact; and, ensuring evaluation cumulatively builds useful theory as to how different types of program trigger change in different contexts.

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