scholarly journals DEVELOPMENT OF NON-INVASIVE METHOD FOR BLOOD MICROCIRCULATION DISORDERS DIAGNOSTICS IN DIABETIC PATIENTS USING LASER DOPPLER FLOWMETRY

2016 ◽  
Vol 1 (31) ◽  
pp. 7-10 ◽  
Author(s):  
A. A. Glazkov ◽  
D. A. Kulikov ◽  
A. V. Dreval’ ◽  
Yu. A. Kovaleva ◽  
V. I. Shumskii ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Diabetic Patients ◽  
Doppler Flowmetry ◽  
Non Invasive ◽  
Blood Microcirculation ◽  
Invasive Method

Evaluation of angiogenesis in chronic inflammation by laser-Doppler flowmetry

1988 ◽  
Vol 74 (2) ◽  
pp. 119-121 ◽  
Author(s):  
C. Orlandi ◽  
C. J. Dunn ◽  
L. G. Cutshaw
Keyword(s):  
Blood Flow ◽  
Chronic Inflammation ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Angiogenic Response ◽  
Non Invasive ◽  
Granulomatous Lesions ◽  
Invasive Method ◽  
Control Skin

1. A non-invasive method is described for the assessment of angiogenesis in chronic inflammation using laser-Doppler flowmetry. 2. Significant increases in capillary blood flow were seen on days 5 and 7 after induction of subcutaneous granulomatous lesions, as compared with control skin. 3. Changes in blood flow were accompanied by changes in pulsatile flow pattern and by an intense angiogenic response observed by light microscopy. 4. The potential application of laser-Doppler flowmetry to quantitative and qualitative studies of evolving angiogenesis in pathological responses is discussed.

scholarly journals Wearable Laser Doppler Flowmetry Sensor: A Feasibility Study with Smoker and Non-Smoker Volunteers

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 201
Author(s):  
Mou Saha ◽  
Viktor Dremin ◽  
Ilya Rafailov ◽  
Andrey Dunaev ◽  
Sergei Sokolovski ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Blood Circulation ◽  
Blood Perfusion ◽  
Pulse Frequency ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Left Hand ◽  
Non Invasive ◽  
Blood Microcirculation ◽  
Left Middle

Novel, non-invasive wearable laser Doppler flowmetry (LDF) devices measure real-time blood circulation of the left middle fingertip and the topside of the wrist of the left hand. The LDF signals are simultaneously recorded for fingertip and wrist. The amplitude of blood flow signals and wavelet analysis of the signal are used for the analysis of blood perfusion parameters. The aim of this pilot study is to validate the accuracy of blood circulation measurements recorded by one such non-invasive wearable LDF device for healthy young non-smokers and smokers. This study reveals a higher level of blood perfusion in the non-smoker group compared to the smoker group and vice-versa for the variation of pulse frequency. This result can be useful to assess the sensitivity of the wearable LDF sensor in determining the effect of nicotine for smokers as compared to non-smokers and also the blood microcirculation in smokers with different pathologies.

scholarly journals Prospects of Laser Doppler flowmetry application in assessment of skin microcirculation in diabetes

2017 ◽  
Vol 20 (4) ◽  
pp. 279-285 ◽  
Author(s):  
Dmitry A. Kulikov ◽  
Alexey A. Glazkov ◽  
Yulia A. Kovaleva ◽  
Natalia V. Balashova ◽  
Alexander V. Kulikov
Keyword(s):  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Regulatory Mechanisms ◽  
Regulatory Function ◽  
Functional Tests ◽  
Skin Microcirculation ◽  
Doppler Flowmetry ◽  
Non Invasive ◽  
Patients With Diabetes ◽  
Invasive Method

This review includes results of scientific and clinical use of laser Doppler flowmetry (LDF) in patients with diabetes mellitus. LDF is a non-invasive method for the quantitative evaluation of microcirculation, which can assess microcirculatory rhythms and conduct functional tests with various impacts, allowing the exploration of regulatory mechanisms of microcirculation. LDF reveals specific diabetes changes in the regulatory function of microcirculation. Microcirculation disturbances, which are traditionally associated with the pathogenesis of complications, also occur in patients with early disorders of carbohydrate metabolism and may precede the manifestation of diabetes. However, this method is still not applied in clinical practice. In this review, we analysed factors limiting the implementation of LDF in practical medicine and suggest ways to improve its clinical significance.

scholarly journals STUDY OF HEMOMICROCIRCULATION IN UPPER- EXTREMITYSKIN IN HEALTHY MEN IN NORMAL CONDITIONS WITH ACCOUNT OF H

2020 ◽  
Vol 10 (4) ◽  
pp. 63-65
Author(s):  
Vadim Astashov ◽  
Valentin Kozlov ◽  
Victor Sidorov, ◽  
Mihail Uloga ◽  
Inna Borodina ◽  
...  
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Peripheral Blood ◽  
Upper Extremities ◽  
Laser Doppler ◽  
Peripheral Blood Flow ◽  
Doppler Flowmetry ◽  
Healthy Men ◽  
Young Males ◽  
Blood Microcirculation

In this study we used laser doppler flowmetry to investigate the parameters of peripheral blood flow in the upper extremities in young males both right- and left-handers. Based on the data obtained we found that in right-handers (dextrals) active mechanisms of regulation of blood microcirculation prevail on the leading hand, In left-handers (sinestrals) active and passive mechanisms of its regulation are involved in the regulation of blood flow on the leading hand (left) and on the opposite (right). However, the contribution of active mechanisms is lower than that of right-handers.

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