scholarly journals Magnetic resonance imaging in the diagnosis of non-tumorous multifocal brain lesions mimicking multiple sclerosis

2020 ◽  
Vol 49 ◽  
Author(s):  
I. A. Krotenkova ◽  
V. V. Bryukhov ◽  
R. N. Konovalov ◽  
M. N. Zakharova ◽  
M. V. Krotenkova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Correct Diagnosis ◽  
Laboratory Data ◽  
Clinical Manifestations ◽  
Brain Lesions ◽  
Resonance Imaging ◽  
Vascular Abnormalities

The diagnosis of multiple sclerosis (MS) is quite challenging due to its variable clinical manifestations and lack of a definitive test. Magnetic resonance imaging (MRI) is one of the tools to confirm the diagnosis and also helps in differential diagnosis with other disorders and in exclusion of MS-mimicking diseases. In this article, based on the analysis of clinical cases, we discuss the differential diagnosis of MS with the following non-tumorous multifocal brain lesions: vascular abnormalities caused by hypoxia and ischemia, cerebral autosomal dominant angiopathy with subcortical infarctions and leukoencephalopathy, Susac syndrome, primary angiitis of the central nervous system, and neurosarcoidosis. We present both MRI criteria for MS and disorders that have similar MRI signs, and additional clinical and laboratory data that is essential for correct diagnosis.

scholarly journals Magnetic Resonance Imaging in the Differential Diagnosis of Multiple Sclerosis and Other Demyelinating Diseases

2019 ◽  
Vol 100 (4) ◽  
pp. 229-236
Author(s):  
I. A. Krotenkova ◽  
V. V. Bryukhov ◽  
R. N. Konovalov ◽  
M. N. Zakharova ◽  
M. V. Krotenkova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Correct Diagnosis ◽  
Laboratory Data ◽  
Demyelinating Diseases ◽  
Resonance Imaging ◽  
Confirmatory Tests ◽  
Magnetic Resonance Imaging Mri

The diagnosis of multiple sclerosis (MS) is quite complicated, which is associated with its clinical features and the lack of unique confirmatory tests. Magnetic resonance imaging (MRI) is one of the ways to confirm the diagnosis and also makes it possible to establish a differential diagnosis with other demyelinating diseases and to exclude diseases that mimic MS. This review presents not only MRI criteria for MS and other diseases similar to the MRI pattern, but also additional clinical and laboratory data, without which it is impossible to make a correct diagnosis.

scholarly journals Magnetic resonance imaging in the diagnosis of multiple sclerosis

2021 ◽  
Vol 2 (3) ◽  
pp. 17-24
Author(s):  
I. A. Krotenkova ◽  
S. N. Morozova ◽  
V. V. Bryukhov ◽  
M. V. Krotenkova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Clinical Data ◽  
Clinical Performance ◽  
Correct Diagnosis ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Multiple sclerosis (MS) diagnosisis is rather difficult due to specifics of clinical performance and the lack of specific tests. Magnetic resonance imaging (MRI) is one of the ways to confirm MS, and also allows differential diagnosis with other diseases and rulling out other pathologies that can mimic MS. This article provides detailed information on visualization of demyelinating processes, as well as pathogenetic and clinical data, without knowledge of which correct diagnosis is impossible.

scholarly journals Pulvinar sign in a case of anti-HU paraneoplastic encephalitis

2016 ◽  
Vol 29 (6) ◽  
pp. 436-439 ◽  
Author(s):  
Pierre-Luc Gamache ◽  
Maude-Marie Gagnon ◽  
Martin Savard ◽  
François Émond
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Clinical Manifestations ◽  
Resonance Imaging ◽  
Paraneoplastic Encephalitis ◽  
Jakob Disease ◽  
Magnetic Resonance Imaging Mri ◽  
Work Up

This article reports the case of a 68-year-old patient with anti-HU antibodies paraneoplastic encephalitis. The clinical manifestations were atypical and the paraclinical work-up, notably the magnetic resonance imaging (MRI) showing bilateral posterior thalamic hyperintensities (pulvinar sign), misleadingly pointed towards a variant Creutzfeld–Jakob disease. After presenting the case, the differential diagnosis of the pulvinar sign is discussed along with other important diagnostic considerations.

scholarly journals Nodular Regenerative Hyperplasia of Liver Mimicking Cirrhosis: a Case Report

2013 ◽  
Vol 2 (3) ◽  
pp. 137-140
Author(s):  
Rui-dan Zheng ◽  
Zhuo-ran Chen ◽  
Jian-neng Chen ◽  
Hui-yong Zhang
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Liver Biopsy ◽  
Sinus Bradycardia ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
Nodular Regenerative Hyperplasia ◽  
Resonance Imaging ◽  
Abdominal Ultrasonography ◽  
Pathologic Features

Abstract A 34-year-old man with no history of any abdominal pain or fatigue was admitted to our hospital in June 2008 due to the cirrhosis found incidentally during a physical examination. Laboratory examination, electrocardiograph, abdominal ultrasonography and magnetic resonance imaging were carried out during his hospitalization. However, according to the results of the above measures, the diagnosis of nodular regenerative hyperplasia of the liver (NRHL) could not be made. The result of electrocardiograph showed there was no sinus bradycardia. The abdominal ultrasonography showed evidence of hepatosplenomegaly, and magnetic resonance imaging showed multiple non-enhancing hepatic nodules. Histologic confirmation was available by means of liver biopsy and the definitive diagnosis of NRHL was confirmed histologically by liver biopsy. NRHL always presents with signs of portal hypertension with little evidence of obvious liver disease, NRHL may mimick the cirrhosis of liver and be easily confused with cirrhosis of the liver nodules, so liver biopsy should be recommended for correct diagnosis. We here report the clinical, radiological and pathologic features of this case with NRHL in order to familiarize the physicians with its clinical manifestations.

scholarly journals Problem of differential diagnostics of neurodegenerative pathology

2019 ◽  
Vol 84 (3) ◽  
pp. 49-54
Author(s):  
M.E. Chernenko
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Brain Magnetic Resonance Imaging ◽  
Dynamic Monitoring ◽  
Differential Diagnostics ◽  
Resonance Imaging ◽  
Adequate Treatment ◽  
Rate Of Increase

The differential diagnosis of multiple sclerosis and Wilson–Konovalov’s disease is an important clinical task, the timely appointment of adequate therapy depends on the correct solution of which. With the seemingly simple differential diagnosis of these diseases, in some cases, especially atypical, there are certain difficulties in making the correct diagnosis. Magnetic resonance imaging is a mandatory study in the structure of a comprehensive examination of patients with multiple sclerosis and Wilson–Konovalov’s disease. Conducting standardized magnetic resonance imaging scans performed on a high-field tomograph is mandatory in all cases of differential diagnosis in patients with demyelinating pathology of the central nervous system and neurodegenerative diseases. An analysis of the topography of focal changes in dynamics, an assessment of the rate of increase of atrophic changes is of great importance for the timely appointment of adequate treatment, which in turn directly affects the prognosis of the disease. The brain magnetic resonance imaging data from 30 patients with multiple sclerosis and 10 patients with Wilson–Konovalov’s disease who were treated at the GU INPN NAMS of Ukraine (Kharkov) were described. It is concluded that both multiple sclerosis and Wilson–Konovalov’s disease are chronic partially controlled diseases in which dynamic monitoring is extremely important, an integral part of which is the conduct of adequate neuroimaging. None of the methods for diagnosing multiple sclerosis and Wilson–Konovalov’s disease has independent diagnostic value, and diagnosis is possible only with a comprehensive analysis of clinical, laboratory, genetic and neuroimaging data.

scholarly journals Osteomyelitis in heterotopic ossification in a patient with congenital gigantism of the leg

2021 ◽  
Vol 6 (5) ◽  
pp. 141-145
Author(s):  
Martina Galea Wismayer ◽  
Kurstein Sant ◽  
Ryan Giordmaina ◽  
Martin McNally
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Heterotopic Ossification ◽  
Correct Diagnosis ◽  
Surgical Excision ◽  
Resonance Imaging ◽  
First Report ◽  
Macrodystrophia Lipomatosa

Abstract. This paper presents the first report of osteomyelitis in heterotopic ossification in a patient with macrodystrophia lipomatosa. Careful review of magnetic resonance imaging allowed correct diagnosis and design of a limited surgical excision. Osteomyelitis should be considered in the differential diagnosis of pain and discharge when heterotopic ossification is present.

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