Probiotics for the Prevention of Necrotizing Enterocolitis

2008 ◽  
Vol 27 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Janeen Gaul
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Bacterial Colonization ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
Low Birth Weight Infants ◽  
Intestinal Epithelia ◽  
Live Bacteria

Necrotizing enterocolitis (NEC) remains a significant cause of morbidity and mortality for low birth weight premature infants. Prematurity, ischemia, formula feeding, and bacterial colonization are risk factors for the self-perpetuating cycle of damaged intestinal epithelia, inflammation, bacterial entry, sepsis, and shock that characterizes NEC. Probiotics are food supplements containing live bacteria that benefit the recipient by improving the microflora balance within the intestine. Several studies suggest that the administration of probiotics may have a prophylactic effect for NEC and may reduce morbidity and mortality rates for low birth weight infants.

scholarly journals The efficacy of fortified human milk compared to human milk alone for the growth of low birth weight infants

2016 ◽  
Vol 43 (5) ◽  
pp. 177 ◽  
Author(s):  
Dewi Kumara Wati Ketut ◽  
Soetjiningsih Soetjiningsih ◽  
Suandi IKG ◽  
Hamid H A
Keyword(s):  
Adverse Effect ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Human Milk ◽  
Premature Infants ◽  
Head Circumference ◽  
Controlled Trial ◽  
Calorie Intake ◽  
Low Birth Weight Infants ◽  
Length Increment

Objective To evaluate the growth of low birth weight infants fedby fortified human milk (FHM) compared to human milk (HM) alone.Methods Sixty premature infants enrolled in this study and ran-domly assigned to have FHM and HM delivered by infusofeedpump,in parallel, non-blinded controlled trial. All patients were followeduntil day 30 or until discharge, whichever came first. The weightgain was recorded daily, while length and head circumference in-crement were recorded weekly.Results The FHM group gained more weight than the HM group(335.0+55.5 g vs. 290.6+108.4 g, p=0.000, 95%CI -170.2;-81.2),larger length increment (1.9+1.1cm vs. 1.2+0.4cm, p=0.000, 95%CI-1.37;-0.55), and larger head increment (1.87+1.1cm vs.0.91+0.43cm, 95%CI -1.37;-0.55). A similar result was found whenthe group was divided into subgroup of 1000-1499 g and 1500-1999 g birth weight. The larger calorie intake in the FHM groupwas the reason for better growth. No adverse effect related to theintervention was found.Conclusion The study shows the benefit of FHM in growth of lowbirth weight infants, which is consistent when the group is dividedinto 1000-1499 g birth weight and 1500-1999 g birth weight subgroups. Better growth is achieved through higher calorie intake inthe FHM group. No adverse effect is found as a consequence ofintervention

scholarly journals ON THE SUBJECT OF MEDICAL/SOCIAL ASPECTS OF REHABILITATION FOR VERY-LOW-BIRTH WEIGHT INFANTS IN EARLY CHILDHOOD

2019 ◽  
Vol 20 (1) ◽  
pp. 30-35
Author(s):  
A. V. Migali ◽  
K. A. Kazakova ◽  
Yu. S. Akoyev ◽  
V. M. Studenikin ◽  
M. A. Varichkina ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Very Low Birth Weight ◽  
Intensive Therapy ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Team Care ◽  
Care Approach ◽  
Paroxysmal Disorders

Innovative technologies in the reanimation and intensive therapy permitted to improve the survival of premature infants, including those with extremely low birth weight infants. There are considered various issues of practical medical care for very-low-birth weight infants in the first three years of life. The special attention is given to patients with bronchopulmonary dysplasia (BPD). There is briefly presented the own authors’ experience of the observation for premature infants in conditions of a multidisciplinary team care approach. There were described such important aspects of the mentioned category of patients as neurodietology/nutritional rehabilitation, compliance with aseptic environmental conditions, the correction of visual and hearing impairment, treatment of neurological deficit, especially neuropharmacology, treatment of paroxysmal disorders and epilepsy.

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