Prediction of Vocational Rehabilitation Outcome in Schizophrenia: Incremental Prognostic Validity of Learning Potential Beyond Basic Cognitive Performance

2009 ◽  
Vol 8 (1) ◽  
pp. 52-62 ◽  
Author(s):  
Stefan Watzke ◽  
Peter Brieger ◽  
Karl H. Wiedl

This article examines learning potential as a predictor of the success of a vocational rehabilitation program for patients with severe mental illness in Germany. Forty-one schizophrenia patients completed a pretest–training–posttest version of the Wisconsin Card Sorting Test as a measure of learning potential. Pretest scores indicated basic cognitive performance, and posttest scores indicated individual learning potential. Rehabilitation outcome was assessed using measures for work capability during the rehabilitation program and the level of vocational integration at 3-month follow-up. Individual learning potential was a better predictor of work capability and the level of vocational reintegration than basic cognitive performance. Our study demonstrates that learning potential is an informative predictor for rehabilitation outcome and adds information beyond basic cognitive performance.

2009 ◽  
Vol 63 (5) ◽  
pp. 405-411 ◽  
Author(s):  
Anja Vaskinn ◽  
Kjetil Sundet ◽  
Svein Friis ◽  
Torill Ueland ◽  
Carmen Simonsen ◽  
...  

2014 ◽  
Vol 20 (10) ◽  
pp. 1034-1044 ◽  
Author(s):  
Hileen Boosman ◽  
Johanna M.A. Visser-Meily ◽  
Tamara Ownsworth ◽  
Ieke Winkens ◽  
Caroline M. Van Heugten

AbstractThe dynamic Wisconsin Card Sorting Test (dWCST) examines the effects of brief training on test performance where pre- to post-test change reflects learning potential. The objective was to examine the validity of the dWCST as a measure of learning potential in patients with acquired brain injury (ABI). A total of 104 patients with ABI completed the dWCST at rehabilitation admission. Performance of a subgroup (n=63) was compared to patients (n=28) who completed a repeated administration of the conventional WCST (rWCST). Furthermore, dWCST performance was compared between patients with ABI (n=63) and healthy controls (n=30) matched on gender, age, and education. Three learning potential indices were used: post-test score, gain score, and a group classification (decliners, poor learners, strong learners, high achievers). The median dWCST administration time was 30 min. The dWCST showed no floor or ceiling effects and the post-test and gain score were significantly intercorrelated. The pre-test score showed no significant associations with other neuropsychological tests. The learning potential indices were significantly associated with language and/or memory. In contrast to the dWCST group, the rWCST group showed no significant pre- to post-test improvement. There were significantly more poor learners in the rWCST group. Compared to controls, patients obtained similar gains, but significantly lower pre- and post-test scores for the dWCST. The ratio of poor learners between-groups was not significantly different. The results support the validity of the dWCST for assessing learning potential in patients with ABI. Further research is needed to investigate the predictive validity of the dWCST. (JINS, 2014, 20, 1–11)


2019 ◽  
Vol 19 (6) ◽  
pp. 405-418
Author(s):  
Maciej Bieliński ◽  
Natalia Lesiewska ◽  
Roman Junik ◽  
Anna Kamińska ◽  
Andrzej Tretyn ◽  
...  

Background:Obesity is a chronic condition associated with poorer cognitive functioning. Wisconsin Card Sorting Test (WCST) is a useful tool for evaluating executive functions. In this study, we assessed the association between dopaminergic gene polymorphisms: DAT1 (SLC6A3), COMTVal158Met, DRD4 (48-bp variable number of tandem repeats - VNTR) and WCST parameters to investigate the functions of the frontal lobes in obese individuals.Objective:To find the significant correlations between polymorphisms of DAT1, COMTVal158Met, DRD4 and executive functions in obese subjects.Methods:The analysis of the frequency of individual alleles was performed in 248 obese patients (179 women, 69 men). Evaluation of the prefrontal cortex function (operating memory and executive functions) was measured with the Wisconsin Card Sorting Test (WCST). Separate analyzes were performed in age subgroups to determine different activities and regulation of genes in younger and older participants.Results:Scores of WCST parameters were different in the subgroups of women and men and in the age subgroups. Regarding the COMT gene, patients with A/A and G/A polymorphisms showed significantly better WCST results in WCST_P, WCST_CC and WCST_1st. Regarding DAT1 men with L/L and L/S made less non-perseverative errors, which was statistically significant. In DRD4, significantly better WCST_1st results were found only in older women with S allele.Conclusion:Obtained results indicate the involvement of dopaminergic transmission in the regulation of prefrontal cortex function. Data analysis indicates that prefrontal cortex function may ensue, from different elements such as genetic factors, metabolic aspects of obesity, and hormonal activity (estrogen).


2017 ◽  
Vol 31 (3) ◽  
pp. 407-418 ◽  
Author(s):  
Gema Díaz-Blancat ◽  
Juan García-Prieto ◽  
Fernando Maestú ◽  
Francisco Barceló

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