scholarly journals Biological, physical and chemical synthesis of silver nanoparticles and their non-toxic bio-chemical application: A brief review

2022 ◽  
Vol 11 (2) ◽  
Author(s):  
Rabia Kanwar
2020 ◽  
Vol 21 (supplement 1) ◽  
Author(s):  
Anandalakshmi K .

The present review focused the biosynthesis of silver nanoparticles (AgNPs) using plant, bacteria and fungi. Green route of AgNPs could be provided the advantage over the physical and chemical synthesis methods. The conventional methods for the production of NPs were expensive, toxic and non-environment friendly. To overcome these problems, many researchers had been found the precise green route. This review described the methods of green synthesis of silver nanoparticles and their mechanism of antibacterial activity.


2021 ◽  
pp. 0958305X2198988
Author(s):  
Nur Syakirah Rabiha Rosman ◽  
Noor Aniza Harun ◽  
Izwandy Idris ◽  
Wan Iryani Wan Ismail

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.


2021 ◽  
Vol 09 ◽  
Author(s):  
Sarvat Zafar ◽  
Aiman Zafar ◽  
Fakhra Jabeen ◽  
Miad Ali Siddiq

: Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.


2022 ◽  
pp. 21-53
Author(s):  
Belete Asefa Aragaw ◽  
Melisew Tadele Alula ◽  
Stephen Majoni ◽  
Cecil K. King'ondu

2020 ◽  
Vol 1 (7) ◽  
pp. 2332-2338
Author(s):  
Marryam Mahmood ◽  
Mehwish Abid ◽  
Muhammad Faizan Nazar ◽  
Muhammad Nadeem Zafar ◽  
Muhammad Asam Raza ◽  
...  

Capped silver nanoparticles (AgNPs) are used in many applications in the biomedical field because of their unique structural flexibility.


2013 ◽  
Vol 756 ◽  
pp. 106-111 ◽  
Author(s):  
Selvaraj Arokiyaraj ◽  
Udaya Prakash Nyayiru Kannaian ◽  
Vijay Elakkya ◽  
T. Kamala ◽  
S. Bhuvaneswari ◽  
...  

The aim of the present study is to synthesize silver nanoparticles, using an aqueous floral extract of common Lotus, i.e Nelumbo nucifera. The synthesized nanoparticles were characterized using UV, TEM, EDX, AFM & XRD. The synthesized AgNPs were confirmed due to the colour change from colourless to reddish brown just after the addition of the aqueous floral extract of Nelumbo nucifera. The UV results of AgNPs showed the excitation of surface Plasmon resonance band at 427 nm. TEM results showed that the synthesized AgNPs were uniformed; monodispersed,spherical in shape and the particle size were found to be 77.81 ± 3.54 nm. EDX spectrum of AgNPs confirms strong signals from Ag (64%) and other elements such as C, O and Cl. The morphology of the synthesized AgNPs by AFM analysis resembled the TEM micrograph. The crystalline nature of the AgNPs was confirmed by XRD. The present study concludes that the aqueous floral extract of Nelumbo nucifera could be used as an effective reducing agent for the synthesis of AgNP. The green synthesis ofsilver nanoparticles is non-toxic and cost-effective and thus remains to be an alternative method to other physical and chemical reduction methods.


2019 ◽  
Vol 25 (24) ◽  
pp. 2650-2660 ◽  
Author(s):  
Rajasree Shanmuganathan ◽  
Indira Karuppusamy ◽  
Muthupandian Saravanan ◽  
Harshiny Muthukumar ◽  
Kumar Ponnuchamy ◽  
...  

Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a remarkable impact by converting metallic silver into silver nanoparticles (AgNPs) for better applications. The advancement in technology has improved the synthesis of NPs using biological method instead of physical and chemical methods. Nonetheless, synthesizing AgNPs using biological sources is ecofriendly and cost effective. Till date, AgNPs are widely used as antibacterial agents; therefore, a novel idea is needed for the successful use of AgNPs as therapeutic agents to uncertain diseases and infections. In biomedicine, AgNPs possess significant advantages due to their physical and chemical versatility. Indeed, the toxicity concerns regarding AgNPs have created the need for non-toxic and ecofriendly approaches to produce AgNPs. The applications of AgNPs in nanogels, nanosolutions, silver based dressings and coating over medical devices are under progress. Still, an improvised version of AgNPs for extended applications in an ecofriendly manner is the need of the hour. Therefore, the present review emphasizes the synthesis methods, modes of action under dissipative conditions and the various biomedical applications of AgNPs in detail.


2013 ◽  
Vol 394 (1) ◽  
pp. 113-123 ◽  
Author(s):  
Radoslaw Szmyd ◽  
Anna Grazyna Goralczyk ◽  
Lukasz Skalniak ◽  
Agnieszka Cierniak ◽  
Barbara Lipert ◽  
...  

Abstract Silver nanoparticles (AgNPs) have many biological applications in biomedicine, biotechnology and other life sciences. Depending on the size, shape and the type of carrier, AgNPs demonstrate different physical and chemical properties. AgNPs have strong antimicrobial, antiviral and antifungal activity, thus they are used extensively in a range of medical settings, particularly in wound dressings but also in cosmetics. This study was undertaken to examine the potential toxic effects of 15 nm polyvinylpyrrolidone-coated AgNPs on primary normal human epidermal keratinocytes (NHEK). Cells were treated with different concentrations of AgNPs and then cell viability, metabolic activity and other biological and biochemical aspects of keratinocytes functioning were studied. We observed that AgNPs decrease keratinocyte viability, metabolism and also proliferatory and migratory potential of these cells. Moreover, longer exposure resulted in activation of caspase 3/7 and DNA damage. Our studies show for the first time, that AgNPs may present possible danger for primary keratinocytes, concerning activation of genotoxic and cytotoxic processes depending on the concentration.


Molecules ◽  
2016 ◽  
Vol 21 (11) ◽  
pp. 1478 ◽  
Author(s):  
Mohammed Shaik ◽  
Ghadeer Albalawi ◽  
Shams Khan ◽  
Merajuddin Khan ◽  
Syed Adil ◽  
...  

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