Changes in the temporal variability of the EEG functional connectivity
                        during aging

This work is aimed at investigating changes in the temporal variability of EEG functional connectivity (FC) during agin. The variability in the FC has been linked to cognitive performance. The study was carried out in two groups of healthy subjects: one of 10 adults between 50-65 years old and another of 15 subjects ranging 66-85 years. EEG recordings were made at rest using 16 monopolar channels: under eyes closed (EC) and under hyperventilation (HV). The cortical FC between all EEG channel pairs was estimated from an index (L) of nonlinear generalized synchronization. For each subject and condition, the global connectivity (GC) of each area/channel with the rest of them was calculated, then the GC average and the GC temporal variability (TVC) of such connectivities was computed from the GC mean and standard deviation of successive EEG recordings respectively. The changes with age and condition of GC and TVC of each cortical area were estimated via a MANOVA. We found that the GC does not change with age during OC or HV, but the TVC of all cortical areas is significantly higher (p<0.01) for subjects under 65 and mainly for the central, temporal and parietal areas (p<0.01). It is concluded that TVC decreasing with aging may be related to cognitive performance deficits.

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Changes during aging in the electroencephalographic cortical synchronization under visual stimulation

European Journal of Investigation in Health, Psychology and Education ◽

10.1989/ejihpe.v6i1.145 ◽

2015 ◽

Vol 6 (1) ◽

pp. 15-26

Author(s):

Guzmán Alba ◽

Almudena González ◽

Julián J. González

Keyword(s):

Repeated Measures ◽

Visual Stimulation ◽

Elderly Subjects ◽

Generalized Synchronization ◽

Cortical Areas ◽

Eyes Closed ◽

Healthy Elderly ◽

The Mean ◽

Eeg Recordings ◽

Healthy Elderly Subjects

This paper analyzes changes during aging in the electroencephalographic (EEG) synchronization between different areas of the cerebral cortex in healthy elderly subjects under visual stimulation. Two groups were selected: one (A) of 10 adults aged 50-65 years and another (B) of 15 subjects aged 66-80 years. EEG recordings of 16 "monopolar" channels were carried out (digitized at 256 Hz), all referenced to the mean and following the standard 10-20 system, and were performed at rest with eyes closed under visual stimulation. From an index (L) of nonlinear generalized synchronization, the average cortical synchronization (ACS) of each channel with the rest and the corresponding average asymmetry in the synchronization (ACM) was estimated. Changes with age (A vs. B) in cortical synchronization and in average interhemispheric asymmetry for all cortical areas were estimated via a repeated measures MANOVA. The results show that under visual stimulation, the SCM decreases with age for most channels (p < 0.01) except for the frontals. The channels that showed asymmetry in the synchronization (p < 0.01) were the frontals F3, F4 y Fp2, the parietal P3 and the temporal T5, in all of them a significant reduction in asymmetry with age (p < 0.01) was observed.

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Changes during aging in the electroencephalographic cortical synchronization under visual stimulation

European Journal of Investigation in Health, Psychology and Education ◽

10.3390/ejihpe6010002 ◽

2015 ◽

Vol 6 (1) ◽

pp. 15-26

Author(s):

Guzmán Alba ◽

Almudena González ◽

Julián J. González

Keyword(s):

Repeated Measures ◽

Visual Stimulation ◽

Elderly Subjects ◽

Generalized Synchronization ◽

Cortical Areas ◽

Eyes Closed ◽

Healthy Elderly ◽

The Mean ◽

Eeg Recordings ◽

Healthy Elderly Subjects

This paper analyzes changes during aging in the electroencephalographic (EEG) synchronization between different areas of the cerebral cortex in healthy elderly subjects under visual stimulation. Two groups were selected: one (A) of 10 adults aged 50-65 years and another (B) of 15 subjects aged 66-80 years. EEG recordings of 16 "monopolar" channels were carried out (digitized at 256 Hz), all referenced to the mean and following the standard 10-20 system, and were performed at rest with eyes closed under visual stimulation. From an index (L) of nonlinear generalized synchronization, the average cortical synchronization (ACS) of each channel with the rest and the corresponding average asymmetry in the synchronization (ACM) was estimated. Changes with age (A vs. B) in cortical synchronization and in average interhemispheric asymmetry for all cortical areas were estimated via a repeated measures MANOVA. The results show that under visual stimulation, the SCM decreases with age for most channels (p < 0.01) except for the frontals. The channels that showed asymmetry in the synchronization (p < 0.01) were the frontals F3, F4 y Fp2, the parietal P3 and the temporal T5, in all of them a significant reduction in asymmetry with age (p < 0.01) was observed.

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Assessment of aging by cortical functional connectivity estimated through synchronization electroencephalographic measurements

European Journal of Investigation in Health, Psychology and Education ◽

10.3390/ejihpe5010012 ◽

2014 ◽

Vol 5 (1) ◽

pp. 121-131

Author(s):

Julián J. González ◽

Almudena González

Keyword(s):

Functional Connectivity ◽

Coherence Function ◽

Sampling Rate ◽

Generalized Synchronization ◽

Brain Areas ◽

Delta Band ◽

Eeg Connectivity ◽

Eeg Recordings ◽

Eeg Functional Connectivity ◽

Local Averages

This work was aimed to study the physiological cerebral aging from the analysis of functional electroencephalographic (EEG) connectivity between different cortical areas in two groups of healthy subjects between 50-65 years and between 66-80 years. With this purpose, digital monopolar EEG recordings were carried out at rest and closed eyes, taking as sampling rate, 256 Hz and as reference, the average of the 16 channels recorded (6-frontals, 4-temporals, 2-centrals, 2-parietal, 2-occipital). The functional cortical connectivity was estimated from the interdependence between channels using the coherence function in the frequency bands delta/theta/alpha/beta, and an index (L) of nonlinear generalized synchronization. The pairwise connectivity between all possible channels and a global connectivity between each channel and all others was computed. The results show that certain local interdependencies measured by the index L and by the delta band coherence, decreased with age; these were especially significant for the temporal-occipital-central connections. Moreover, a significant linear decrease with age of the interdependence indices aforementioned for the pair and local averages was observed. Also global interdependencies, especially those of nonlinear type, for certain central-lateral and posterior areas, decline with age. It is concludes that individual and global measures of EEG functional connectivity between certain brain areas can help to objectively evaluate the neurophysiological aging.

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Assessment of aging by cortical functional connectivity estimated through synchronization electroencephalographic measurements

European Journal of Investigation in Health, Psychology and Education ◽

10.1989/ejihpe.v1i1.96 ◽

2014 ◽

Vol 5 (1) ◽

pp. 121-131

Author(s):

Julián J. González ◽

Almudena González

Keyword(s):

Functional Connectivity ◽

Coherence Function ◽

Sampling Rate ◽

Generalized Synchronization ◽

Brain Areas ◽

Delta Band ◽

Eeg Connectivity ◽

Eeg Recordings ◽

Eeg Functional Connectivity ◽

Local Averages

This work was aimed to study the physiological cerebral aging from the analysis of functional electroencephalographic (EEG) connectivity between different cortical areas in two groups of healthy subjects between 50-65 years and between 66-80 years. With this purpose, digital monopolar EEG recordings were carried out at rest and closed eyes, taking as sampling rate, 256 Hz and as reference, the average of the 16 channels recorded (6-frontals, 4-temporals, 2-centrals, 2-parietal, 2-occipital). The functional cortical connectivity was estimated from the interdependence between channels using the coherence function in the frequency bands delta/theta/alpha/beta, and an index (L) of nonlinear generalized synchronization. The pairwise connectivity between all possible channels and a global connectivity between each channel and all others was computed. The results show that certain local interdependencies measured by the index L and by the delta band coherence, decreased with age; these were especially significant for the temporal-occipital-central connections. Moreover, a significant linear decrease with age of the interdependence indices aforementioned for the pair and local averages was observed. Also global interdependencies, especially those of nonlinear type, for certain central-lateral and posterior areas, decline with age. It is concludes that individual and global measures of EEG functional connectivity between certain brain areas can help to objectively evaluate the neurophysiological aging.

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Dissociative-Traumatic Dimension and Triple Network: An EEG Functional Connectivity Study in a Sample of University Students

Psychopathology ◽

10.1159/000519563 ◽

2021 ◽

pp. 1-9

Author(s):

Giuseppe Alessio Carbone ◽

Claudio Imperatori ◽

Francesco Saverio Bersani ◽

Chiara Massullo ◽

Egle Maria Orlando ◽

...

Keyword(s):

Functional Connectivity ◽

University Students ◽

Posterior Parietal Cortex ◽

Self Report ◽

Connectivity Pattern ◽

Eyes Closed ◽

Dissociative Symptoms ◽

Trauma Ct ◽

Eeg Functional Connectivity ◽

The Right

Aims: We investigated the association among triple network electroencephalographic (EEG) functional connectivity, dissociative symptoms, and childhood trauma (CT) in a sample of university students. Sampling and Methods: Seventy-six participants (30 males and 46 females; mean age 22.12 ± 2.35) completed self-report measures investigating dissociative symptoms, CT, and depressive symptoms. Participants also performed an eyes-closed resting-state EEG recording. EEG analyses were conducted through the exact low-resolution electromagnetic tomography (eLORETA) software. Results: A 2-step cluster analysis revealed 2 groups: participants (N = 23) with high dissociative-traumatic dimension symptoms (DTD+) and participants (N = 53) with low DTD symptoms (DTD−). Compared to DTD− subjects, DTD+ participants showed decreased theta connectivity between the salience network (SN) and central executive network (CEN), specifically between the right anterior insula and the left posterior parietal cortex. No significant correlation was detected between EEG data and clinical variables. Conclusion: Our results raise the possibility of a dysfunctional connectivity pattern occurring between the SN and CEN in individuals with high DTD symptoms. Such connectivity pattern might reflect the neuropsychophysiological disintegration related to pathological dissociation.

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Dynamic changes of ICA power spectra-derived EEG functional connectivity between eyes open and eyes closed states: Resting state network

Neuroscience Letters ◽

10.1016/j.neulet.2011.05.172 ◽

2011 ◽

Vol 500 ◽

pp. e36

Author(s):

Jean-Lon Chen ◽

Tomas Ros ◽

John Gruzelier

Keyword(s):

Functional Connectivity ◽

Resting State ◽

Power Spectra ◽

Dynamic Changes ◽

Resting State Network ◽

Eyes Closed ◽

Eyes Open ◽

Eeg Functional Connectivity

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P410: Temporal variability in EEG functional connectivity in children with attention deficit hyperactivity disorder

Clinical Neurophysiology ◽

10.1016/s1388-2457(14)50518-4 ◽

2014 ◽

Vol 125 ◽

pp. S159

Author(s):

G. Alba ◽

L.D. Méndez ◽

S. Mañas ◽

A. Gamundi ◽

E. Pereda ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Functional Connectivity ◽

Attention Deficit ◽

Temporal Variability ◽

Hyperactivity Disorder ◽

Eeg Functional Connectivity

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Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI

Salud Mental ◽

10.17711/sm.0185-3325.2019.012 ◽

2019 ◽

Vol 42 (2) ◽

pp. 91-100 ◽

Cited By ~ 1

Author(s):

Marlene Galicia-Alvarado ◽

Javier Alducin-Castillo ◽

Maura Jazmín Ramírez-Flores ◽

Ana Laura Sánchez Quezada ◽

Oscar Yáñez-Suárez ◽

...

Keyword(s):

Functional Connectivity ◽

Cognitive Performance ◽

Cross Sectional Study ◽

Phase Method ◽

Healthy Children ◽

Spectral Coherence ◽

Subtle Difference ◽

Cross Sectional ◽

Eyes Closed ◽

Parietal Lobes

Introduction. TBI is associated with alterations in cortico-subcortical connectivity. However, little attention has been paid to its clinical characteristics and functional connectivity in pediatric patients with chronic TBI. Objective. To evaluate the cognitive performance and spectral coherence of a group of children with TBI in non-acute phase. Method. Cross-sectional study of 15 children with chronic TBI and 17 healthy children. The Neuropsychological Assessment of Children (Evaluación Neuropsicológica Infantil, ENI) was used and the resting activity of the EEG with eyes-closed was recorded. Offline, two-second epochs of the EEG of each participant were chosen and the spectral coherence was estimated in a range of 1.6 to 30 Hz. The cognitive performance between groups was compared with T-test/Mann-Whitney U Test and MANOVA for the coherence values. Results. The TBI group showed a lower performance (p ≤ 0.05) in metalinguistic, visuospatial skills, attention, memory, non-verbal flexibility, planning, and organization. Differences (p ≤ 0.000) were found both inter and intrahemispherically in the spectral coherence between the groups, particularly on F1-F3 (95% CI: 0.543 - 0.557) over the whole frequency range and F3-C3 (95% CI: 0.503 - 0.515) in delta, theta, alpha2, and beta frequencies. Discussion and conclusión. Our findings suggest alterations of hypo and hyper functional connectivity, particularly on the frontal and parietal lobes of both hemispheres, even after several years of a TBI. It is possible that a subtle difference in the degree of connectivity is crucial in the genesis or successful development of attentional, mnesic, executive, and visuospatial processes.

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