scholarly journals Mesotelioma Intraparenquimatoso Difuso: Uma Apresentação Rara

2020 ◽  
Vol 33 (2) ◽  
pp. 143
Author(s):  
Ana Pais ◽  
Nicole Pinto ◽  
João Cardoso ◽  
Manuel Fernandes ◽  
Ana Isabel Coutinho ◽  
...  
Keyword(s):  
Poor Prognosis ◽  
Malignant Neoplasm ◽  
Pleural Mesothelioma ◽  
Organizing Pneumonia ◽  
Imaging Studies ◽  
Cryptogenic Organizing Pneumonia ◽  
History Of ◽  
Bronchopulmonary Infection ◽  
Pleural Neoplasm ◽  
Pleural Involvement

Pleural mesothelioma is a disease associated with exposure to asbestos. Although rare, it is the most common malignant pleural neoplasm. It is difficult to diagnose and it has a poor prognosis. We report the case of a 62-year-old male patient with a history of prolonged occupational exposure to asbestos, with dyspnea for minor exertion and productive cough, for several months. Imaging studies revealed extensive interstitial involvement with marked thickening of the interlobular and centrilobular septa and tenuous pleural involvement. Several differential diagnoses were considered such as, asbestosis, cryptogenic organizing pneumonia, desquamative interstitial pneumonia, pleuropulmonary metastases, and/or bronchopulmonary infection, but the histological and immunohistochemical results were compatible with pleural mesothelioma - a rare malignant neoplasm, with pleural origin, with a high mortality rate.

scholarly journals Benign Pleural Multicystic Mesothelioma: A Rare Case Report

2021 ◽  
Author(s):  
Alireza Rezvani ◽  
SeyedehMaryam Pishva ◽  
Amirhossein Erfani ◽  
Ahmad Monabati ◽  
Bizhan Ziaian ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Cough ◽  
Rare Case ◽  
Pleural Mesothelioma ◽  
Case Presentation ◽  
Rare Case Report ◽  
History Of ◽  
The Right ◽  
Lateral Thoracotomy ◽  
Pleural Involvement

Abstract Background: Fewer than 200 benign multicystic peritoneal mesothelioma cases were reported worldwide till 2017, while its pleural involvement has rarely been reported. Case presentation: We report a 70-year-old man who presented with three months history of chronic cough. Surgical resection was performed, and the pathology confirmed benign multicystic pleural mesothelioma. The patient underwent right lateral thoracotomy, wedges resection of the right upper lobe, and parietal pleurectomy and was discharged with an uneventful postop course.Conclusion: Based on published literature to date, this is the second reported case of pleural involvement of this disease.

Giant Botryoid Fibroepithelial Polyp of Bladder with Myofibroblastic Stroma and Cystitis Cystica et Glandularis

2003 ◽  
Vol 6 (2) ◽  
pp. 179-181 ◽  
Author(s):  
Hikmat Al-Ahmadie ◽  
Ana M. Gomez ◽  
Nicholas Trane ◽  
Kevin E. Bove
Keyword(s):  
Stromal Cells ◽  
Malignant Neoplasm ◽  
Filling Defect ◽  
Imaging Studies ◽  
Gross Hematuria ◽  
Cytological Examination ◽  
Single Episode ◽  
History Of ◽  
Cystitis Cystica ◽  
Tract Disorder

A 3-year-old boy presented with a single episode of gross hematuria and no history of previous urinary tract disorder. Imaging studies revealed a large complex polypoid filling defect in the bladder lumen. Several attempts at transurethral biopsy and cytological examination of the urine revealed clumps of benign epithelial cells, but suspicion of a malignant neoplasm such as rhabdomyosarcoma remained high and the lesion was resected. The specimen measured 15 cm, had a narrow zone of attachment to the bladder mucosa, and was grossly botryoid. Changes typical of cystitis cystica et glandularis were present at and near all surfaces. Myxoid stroma contained scattered benign fibroblasts, myofibroblasts, and smooth muscle cells. Inexplicably, one of two karyotyped stromal cells demonstrated a translocation usually associated with rhabdomyosarcoma. This child is well without evidence of bladder abnormality 1.5 years after surgery.

scholarly journals Chronic interstitial pneumonia with features of organizing pneumonia in an adult horse

2020 ◽  
Vol 32 (4) ◽  
pp. 621-625
Author(s):  
Miguel F. Carrillo ◽  
Deborah Kemper ◽  
Leslie W. Woods ◽  
Francisco R. Carvallo
Keyword(s):  
Connective Tissue ◽  
Interstitial Pneumonia ◽  
Bacterial Pneumonia ◽  
Organizing Pneumonia ◽  
Respiratory Problems ◽  
Nodular Pattern ◽  
Quarter Horse ◽  
History Of ◽  
Alveolar Septa ◽  
Formalin Fixed

A 22-y-old American Quarter Horse gelding was presented with a history of chronic progressive respiratory problems and a diffuse pulmonary nodular pattern in thoracic radiographs. The horse was euthanized, and 4 formalin-fixed samples of lung were submitted for histopathology. There were multifocal areas of marked thickening of alveolar septa as a result of proliferation of myofibroblasts embedded in fibromyxoid matrix (interpreted as “Masson bodies”), focal areas of fibrosis, and numerous papillary projections of connective tissue into bronchioles. A diagnosis of organizing pneumonia was reached. No etiology was found for this lesion. It is important to consider causes of chronic interstitial pneumonia with fibrosis in horses other than equid herpesvirus 5, such as complicated viral or bacterial pneumonia or chronic toxicoses.

Episodic versus Chronic Dizziness: An Analysis of Predictive Factors

2021 ◽  
pp. 000348942110254
Author(s):  
Eric J. Formeister ◽  
Ricky Chae ◽  
Emily Wong ◽  
Whitney Chiao ◽  
Lauren Pasquesi ◽  
...  
Keyword(s):  
Multivariate Regression ◽  
Treatment Options ◽  
Depression And Anxiety ◽  
Imaging Studies ◽  
Comorbid Depression ◽  
Cross Sectional ◽  
Tertiary Center ◽  
Chronic Dizziness ◽  
Associated Symptoms ◽  
History Of

Objectives: To elucidate differences in demographic and clinical characteristics between patients with episodic and chronic dizziness. Methods: A cross-sectional, observational study of 217 adults referred for dizziness at 1 tertiary center was undertaken. Subjects were split into a chronic dizziness group (>15 dizzy days per month) and an episodic dizziness group (<15 dizzy days per month). Results: 217 adults (average age, 53.7 years; 56.7% female) participated. One-third (n = 74) met criteria for chronic dizziness. Dizziness handicap inventory (DHI) scores were significantly higher in those with chronic dizziness compared to those with episodic dizziness (53.9 vs 40.7; P < .001). Comorbid depression and anxiety were more prevalent in those with chronic dizziness (44.6% and 47.3% vs 37.8% and 35.7%, respectively; P > .05). Abnormal vestibular testing and abnormal imaging studies did not differ significantly between the 2 groups. Ménière’s disease and BPPV were significantly more common among those with episodic dizziness, while the prevalence of vestibular migraine did not differ according to chronicity of symptoms. A multivariate regression that included age, sex, DHI, history of anxiety and/or depression, associated symptoms, and dizziness triggers was able to account for 15% of the variance in the chronicity of dizziness (pseudo- R2 = 0.15; P < .001). Conclusions: Those who suffer from chronic dizziness have significantly higher DHI and high comorbid rates of depression and anxiety than those with episodic dizziness. Our findings show that factors other than diagnosis alone are important in the chronification of dizziness, an observation that could help improve on multimodal treatment options for this group of patients.

Cryptogenic Organizing Pneumonia

2005 ◽  
Vol 12 (3) ◽  
pp. 153-161 ◽  
Author(s):  
Romain Lazor ◽  
Jean-Fran??ois Cordier
Keyword(s):  
Organizing Pneumonia ◽  
Cryptogenic Organizing Pneumonia

scholarly journals Small Cell Ovarian Cancer in Adolescents: Report of Two Cases and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
M. Rovithi ◽  
A. G. Pallis ◽  
A. Kalykaki ◽  
E. Lagoudaki ◽  
L. Giannikaki ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Combination Chemotherapy ◽  
Poor Prognosis ◽  
Relevant Literature ◽  
Malignant Neoplasm ◽  
Standard Of Care ◽  
Small Cell ◽  
Review Of The Literature

Ovarian small cell carcinoma is a rare and highly malignant neoplasm carrying a poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, no regimen can be recommended as standard of care although in the majority of cases platinum-based regimens are used. Herein, we report two cases of small cell carcinoma of the ovaries along with a review of the relevant literature.

Cryptogenic organizing pneumonia by alectinib

2021 ◽  
Author(s):  
Patricia López Pardo ◽  
Ana María Sánchez Peña ◽  
María Teresa Río Ramírez
Keyword(s):  
Organizing Pneumonia ◽  
Cryptogenic Organizing Pneumonia

Rare case of metastatic adenocarcinoma to the maxillary sinus

2021 ◽  
Vol 14 (9) ◽  
pp. e244485
Author(s):  
Apurwa Prasad ◽  
Taha Alrifai ◽  
Sumathi Vijaya Rangan ◽  
Jessica Garcia
Keyword(s):  
Metastatic Disease ◽  
Colorectal Adenocarcinoma ◽  
Metastatic Adenocarcinoma ◽  
Imaging Studies ◽  
Timely Manner ◽  
Posterior Aspect ◽  
Delay In Diagnosis ◽  
Immune Histochemistry ◽  
History Of ◽  
Intestinal Type Adenocarcinoma

Colorectal carcinoma metastases to the head and neck are exceedingly rare. Patients may present with vague symptoms that may lead to a delay in diagnosis. We report the case of a 51-year-old man with a known history of stage IIIB colorectal adenocarcinoma who presented with right-sided molar tooth bleeding and right-sided palate swelling that led to difficulty speaking, eating and weight-loss of 15 pounds. Imaging studies revealed a 3.1×4.8×3 cm mass that was centred around the posterior aspect of the maxilla. Pathology revealed moderately differentiated intestinal type adenocarcinoma of colonic subtype, immune histochemistry was positive for CDX2, CK20 and MUC2, thus confirming metastatic disease to the maxilla. The patient is undergoing chemoradiation therapy for palliation of his symptoms. Clinicians should be aware of this potentional site of metastatic disease and suspect the diagnosis in a timely manner to avoid delays in making a diagnosis.

A case of nodular episcleritis mimicking a solitary giant episcleral mass

2021 ◽  
pp. 112067212110528
Author(s):  
Lan Zhou ◽  
Juanjuan Wang ◽  
Guihua Xu ◽  
Dingding Wang ◽  
Xiaoyi Wang ◽  
...  
Keyword(s):  
Topical Steroid ◽  
Inflammatory Cells ◽  
Systemic Hypertension ◽  
Eye Drops ◽  
Definite Diagnosis ◽  
Imaging Studies ◽  
Immunohistochemical Examination ◽  
History Of ◽  
Inflammatory Drugs

Purpose To describe an atypical nodular episcleritis mimicking a solitary giant episcleral mass, which is not attributed to any systemic diseases and identified only after immunohistochemical examination. Case report A sixty-year-old Chinese woman with systemic hypertension presented with 6-month history of giant, solitary and redness epibulbar mass arising from the superior aspect of her left eye. The lesion gradually enlarged, even with 6-month history of irregular topical steroid eye drops treatment. Imaging studies and laboratory test revealed a 10 mm × 8 mm episcleral mass absence of any infection indicator and autoimmune antibody changes. The mass was completely removed before its extension through the deep scleral, histopathologic examination revealed a nodular episcleritis composed of various chronic inflammatory cells infiltration. Topical steroid eye drops treatment combined with oral steroidal anti-inflammatory drugs was then administrated regularly for 1 month, and no recurrence occurred after 1-year follow-up. Conclusion Nodular anterior episcleritis is characterized by underlying chronic inflammation of the anterior episclera and can be presented as asymptomatic episcleral mass. Besides a thorough investigation systemically, tissue biopsy is required for definite diagnosis.

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