scholarly journals Association between respiratory tract infections and incidence of falls in nursing home residents

2013 ◽  
Vol 123 (7-8) ◽  
pp. 371-377
Author(s):  
Małgorzata Pigłowska ◽  
Joanna Kostka ◽  
Tomasz Kostka
Keyword(s):  
Nursing Home ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Nursing Home Residents ◽  
Tract Infections

scholarly journals Vitamin E and Respiratory Tract Infections in Elderly Nursing Home Residents

JAMA ◽  
2004 ◽  
Vol 292 (7) ◽  
pp. 828 ◽  
Author(s):  
Simin Nikbin Meydani ◽  
Lynette S. Leka ◽  
Basil C. Fine ◽  
Gerard E. Dallal ◽  
Gerald T. Keusch ◽  
...  
Keyword(s):  
Nursing Home ◽  
Vitamin E ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Nursing Home Residents ◽  
Tract Infections

scholarly journals Impact of Lactoferrin Supplementation on Respiratory Tract Infections in Older Nursing Home Residents: A Protocol for a Randomized Control Trial

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1124-1124
Author(s):  
Carl Burton ◽  
Vivek Sigh ◽  
Rabie Shahzad ◽  
Esther Lan ◽  
Lauren Brink ◽  
...  
Keyword(s):  
Nursing Home ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Nursing Home Residents ◽  
Study Participant ◽  
Controlled Study ◽  
Bovine Lactoferrin ◽  
Secondary Outcomes ◽  
Tract Infections ◽  
The Impact

Abstract Objectives To evaluate the impact of a dietary supplement within an elderly population who reside in a Community Living Center (CLC; VA Nursing Home), on the number of respiratory tract infections (RTIs) during a 90-day study period. Methods This is a randomized, double-blind, placebo-controlled study to evaluate the impact of bovine Lactoferrin (bLf) on RTIs in an elderly nursing home population in the US. Subjects will be residents of the CLC and screened within 21 days prior to starting study supplementation. Eligible participants were at least 55 years of age, able to eat and drink and expected to reside at the CLC for the duration of the study. Consent was obtained from the study participant or their legally recognized representative decision maker. Participants will be excluded if: receiving tube feeds or specialized diets for eating disorders; immunocompromised; have a life expectancy of less than six months; or allergic to study products. Results Subjects will be randomized in a ratio of 1:1 to either investigational (600 mg of bLf) or (placebo arms. All participants will take study supplement by mouth daily for 90 days. Subjects will be assessed daily for RTI symptoms. Blood and saliva will be collected at 45 and 90 days. Ad hoc assessments and a nasal sample will take place if a subject develops a protocol-defined RTI. Conclusions The primary outcome will be number of RTIs over the 90-day study period. Secondary outcomes include severity and duration of RTI symptoms, symptoms associated with RTIs, number of RTI complications, and nasopharyngeal swab at onset of RTI, Other secondary outcomes include the following, all measured at baseline, day 45 and day 90: quality of life by questionnaire, weight, saliva markers, laboratory testing and immunological markers. An exploratory endpoint is vaccine specific inflammatory panel (influenza and Sars-Cov2) measured upon vaccination during supplement period. RTI number, severity, duration and complications and medically confirmed adverse events will be compared between the placebo and investigational groups. Funding Sources RB/Mead Johnson & Company.

scholarly journals Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial

BMJ ◽  
2021 ◽  
pp. n2198 ◽  
Author(s):  
Tjarda M Boere ◽  
Laura W van Buul ◽  
Rogier M Hopstaken ◽  
Maurits W van Tulder ◽  
Jos W M R Twisk ◽  
...  
Keyword(s):  
Nursing Home ◽  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Intervention Group ◽  
Nursing Home Residents ◽  
Control Group ◽  
Antibiotic Prescribing ◽  
Lower Respiratory Tract Infections ◽  
Tract Infections

Abstract Objective To evaluate whether C reactive protein point-of-care testing (CRP POCT) safely reduces antibiotic prescribing for lower respiratory tract infections in nursing home residents. Design Pragmatic, cluster randomised controlled trial. Setting The UPCARE study included 11 nursing home organisations in the Netherlands. Participants 84 physicians from 11 nursing home organisations included 241 participants with suspected lower respiratory tract infections from September 2018 to the end of March 2020. Interventions Nursing homes allocated to the intervention group had access to CRP POCT. The control group provided usual care without CRP POCT for patients with suspected lower respiratory tract infections. Main outcome measures The primary outcome measure was antibiotic prescribing at initial consultation. Secondary outcome measures were full recovery at three weeks, changes in antibiotic management and additional diagnostics during follow-up at one week and three weeks, and hospital admission and all cause mortality at any point (initial consultation, one week, or three weeks). Results Antibiotics were prescribed at initial consultation for 84 (53.5%) patients in the intervention group and 65 (82.3%) in the control group. Patients in the intervention group had 4.93 higher odds (95% confidence interval 1.91 to 12.73) of not being prescribed antibiotics at initial consultation compared with the control group, irrespective of treating physician and baseline characteristics. The between group difference in antibiotic prescribing at any point from initial consultation to follow-up was 23.6%. Differences in secondary outcomes between the intervention and control groups were 4.4% in full recovery rates at three weeks (86.4% v 90.8%), 2.2% in all cause mortality rates (3.5% v 1.3%), and 0.7% in hospital admission rates (7.2% v 6.5%). The odds of full recovery at three weeks, and the odds of mortality and hospital admission at any point did not significantly differ between groups. Conclusions CRP POCT for suspected lower respiratory tract infection safely reduced antibiotic prescribing compared with usual care in nursing home residents. The findings suggest that implementing CRP POCT in nursing homes might contribute to reduced antibiotic use in this setting and help to combat antibiotic resistance. Trial registration Netherlands Trial Register NL5054

scholarly journals Effects of a Combination of Elderberry and Reishi Extracts on the Duration and Severity of Respiratory Tract Infections in Elderly Subjects: A Randomized Controlled Trial

2020 ◽  
Vol 10 (22) ◽  
pp. 8259
Author(s):  
Carlos Gracián-Alcaide ◽  
Jose A. Maldonado-Lobón ◽  
Elisabeth Ortiz-Tikkakoski ◽  
Alejandro Gómez-Vilchez ◽  
Juristo Fonollá ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Sleep Disturbances ◽  
Respiratory Tract Infections ◽  
Controlled Trial ◽  
Winter Season ◽  
Nursing Home Residents ◽  
Elderly Subjects ◽  
Lower Probability ◽  
Healthy Elderly ◽  
Tract Infections

Elderly people are particularly vulnerable to respiratory tract infections, so natural strategies to ameliorate the duration and severity of these infections are of great interest in this population. The objective of this study is to evaluate the efficacy of the consumption of a combination of elderberry and reishi extracts on the incidence, severity, and duration of respiratory tract infections in a group of healthy elderly volunteers. A randomized, double-blind, placebo-controlled pilot study was performed during the winter season. A group of 60 nursing home residents ≥65 years of age was randomly assigned to receive a combination of 1.5 g of elderberry +0.5 g of reishi or a placebo daily for 14 weeks. Data about the health conditions of the volunteers were evaluated and recorded by a medical doctor every 2 weeks. The incidence of respiratory infections was similar in both groups. However, volunteers in the extract group presented a significantly lower duration of common cold events (2.5 vs. 4.8 days, p = 0.033).and a significantly lower probability of having a high severity influenza-like illness event (p = 0.039). Moreover, the incidence of sleep disturbances was significantly lower in the extract group (p = 0.049). Therefore, the administration of a combination of elderberry and reishi extracts to the elderly population during the winter season might be used as a natural strategy to reduce the duration and severity of respiratory tract infections.

scholarly journals Antimicrobial Prophylaxis and Stewardship in Nursing Home: A Narrative Review

2021 ◽  
pp. 1-6
Author(s):  
M. Tandan
Keyword(s):  
Nursing Home ◽  
Urinary Tract ◽  
Nursing Homes ◽  
Respiratory Tract ◽  
Antimicrobial Stewardship ◽  
Antimicrobial Prophylaxis ◽  
Inappropriate Prescribing ◽  
Significant Risk ◽  
Nursing Home Residents ◽  
Tract Infections

The rapid increase in antimicrobial resistance is a great concern in safeguarding the nursing home population. Improving inappropriate prescribing is the main agenda of antimicrobial stewardship. It is complicated to articulate the appropriateness of antimicrobial prescribed in nursing home residents, especially the prophylaxis. It is tricky because most of the residents are often on multiple medications, and there are no guidelines available for prescribers to decide on the appropriateness. Except for urinary tract infections, prescribing instructions rarely exists for other infections in nursing homes. Very few studies discuss prophylactic prescribing, and most of them are prevalence studies. These studies showed the urinary tract, respiratory tract, and skin-related problem as the most common cause of antimicrobial prophylaxis. However, this information is presented as total proportion without disaggregated analysis of conditions and types of the urinary and respiratory tract and skin-related infections. Further, the definition used is vague, and significant risk factors of antimicrobial prophylaxis and precision about the use remain unanswered. Lack of appropriate definition and unanswered questions are potentially challenging for stewardship in nursing homes. This review summarizes the current situation of antimicrobial prophylaxis and discusses gaps in the literature and pertinent areas for moving forward for antimicrobial stewardship in nursing home settings.

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