scholarly journals RISK FACTORS OF TYPE 2 DIABETES MELLITUS DURATION AND NON-COMPLIANCE WITH MEDICATION TO POOR GLYCEMIC STATUS

2020 ◽  
Vol 8 (3) ◽  
pp. 256
Author(s):  
Marisa Gita Putri ◽  
K. Heri Nugroho HS ◽  
Mateus Sakundarno Adi ◽  
Suhartono Suhartono ◽  
Bagoes Widjanarko

Background: Type 2 diabetes mellitus is a chronic disease that is still a global health problem. Uncontrolled diabetes mellitus (DM) can result in poor glycemic status, with factors that affect patients including long-term DM and medication compliance. Purpose: This study aimed to determine the risk factors of long-term DM and non-compliance with medication on the poor glycemic control status of patients with type 2 DM. Methods: This type of research used observational analysis with a case–control design. Samples were taken from patients with type 2 DM, with 40 cases and 40 controls. The criteria for sample inclusion were that the patients had a glycosylated hemoglobin level check, were willing to be research respondents, and could communicate well. The exclusion criterion was patients experiencing a drastic decline in health status during the study. The sampling technique used was consecutive sampling. This research was conducted at the Panti Wilasa Citarum Hospital in Semarang City from July to September 2019. The relationship and the risk of long-term DM and adherence to taking medication with glycemic status were tested using the chi-square test. Results: This study showed that a duration of DM >5 years (p = 0.01; Odss Ratio (OR) = 3.46; 95% confidence interval [CI] = 1.37 < OR < 8.69) and non-compliance with taking medication (p = 0.02; OR = 3.15; 95% CI = 1.25 < OR < 7.93) are risk factors for poor glycemic status. Conclusion: Duration of DM >5 years and non-compliance with taking medication are risk factors for poor glycemic status in patients with type 2 DM.

2020 ◽  
Vol 15 (1) ◽  
pp. 19-21
Author(s):  
Abdullah Al Mamun ◽  
Sheikh Shahidul Islam ◽  
Maj Ariful Haque ◽  
AKM Shafiqur Rahman

Introduction: The increasing prevalence of diabetes over the world has become an important public health issue. It is considered as an independent risk factor for cognitive impairment. The cognitive function of patients with type 2 diabetes mellitus is usually not assessed in routine checkup. Objectives: To evaluate the cognitive status and associated factors of type 2 diabetes mellitus patients. Materials and Methods: This cross-sectional study conducted in Combined Military Hospital, Dhaka from July 2014 to June 2015. A total of 191 type 2 diabetes mellitus patients were studied to find out the association between glycemic status and cognitive capacity among the patients. Cognitive capacity was assessed by using MMSE scale. Data were collected by face to face interview with a semi-structured questionnaire and checklist following systematic random sampling technique. Results: Out of 191 patients 85.3% of the patients had uncontrolled DM but 88% of the patients had normal level of cognitive capacity and only 12% having border line cognitive capacity. More male (16.0%) than female (7.1%) patients had border line cognitive capacity. Statistically significant (p<0.05) association was found with age group and glycemic status, aged group has more uncontrolled diabetes mellitus. Majority (39.4%) of elderly patients (61-80 years) had border line cognitive capacity while most (96.4%) of the younger patients (41-50 years) had normal cognitive capacity. Conclusion: In this study type 2 DM patients found with decline in cognitive capacity. So, patients with type 2 DM should be regularly assessed for their cognitive function. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 19-21


2004 ◽  
Vol 17 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Susan Cornell ◽  
Amber Briggs

Type 2 diabetes mellitus is a multiorgan, metabolic disease associated with multiple microvascular and macrovascular complications. The incidence of type 2 diabetes is growing at an alarming rate. Achieving and maintaining near-normal blood glucose and glycosylated hemoglobin levels (A1C) are of the utmost importance. Existing treatment options for managing type 2 diabetes, which have primarily included sulfonylureas and biguanides, are insufficient at achieving these treatment goals alone, particularly if used long term. The need to explore newer and better treatment options that provide longer lasting glucose control and at the same time focus on targeting cardiovascular risk factors to minimize and prevent the serious complications associated with this multifaceted disease becomes quite obvious.


2015 ◽  
Vol 22 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Carmen Dobjanschi ◽  
Rucsandra Dănciulescu Miulescu

AbstractWomen with gestational diabetes mellitus (GDM) have an increased lifetime risk of developing type 2 diabetes mellitus (T2DM). GDM has a substantial impact on maternal and foetal short and long-term health. Risk factors for GDM may be genetic or nongenetic and have been analysed in numerous studies. Researches in recent years allowed the identification of other risk factors for GDM except for those already known. Knowledge and identification of all risk factors for GDM allows the elaboration of a prevention strategy of T2DM, it may influence the screening, diagnosis, and, subsequently, treatment modalities for this disease.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Faranak Sharifi ◽  
Mohammad Asghari ◽  
Yahya Jaberi ◽  
Oveis Salehi ◽  
Fatemeh Mirzamohammadi

Introduction. The aim of this study was to evaluate the independent predictors of ED in adult men with type 2 diabetes mellitus (T2DM). Methods. We have recruited 200 T2DM patients referred to our center between March 1, 2009 and March 1, 2010. All the patients were scored with the International Index of Erectile Function (IIEF)-5 questionnaires. Contribution of age, body mass index (BMI), smoking, blood pressure, lipid profile, fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), free testosterone concentration, and duration of diabetes to risk of ED were evaluated. Results. Of 200 men with T2DM, 59.5% had ED (95%CI: 52%–67%). A negative significant correlation was found between potency score and HbA1c (r: 0.20,P: 0.01), FPG (r: 0.17, P: 0.03) and SBP (r: 0.18, P: 0.02) but not between other risk factors such as lipid profile, BMI, and serum testosterone level. By using multivariate logistic regression analysis, we found out that the only two independent predictors of ED in these group of patients are age (OR: 2.8, P: 0.01), and taking calcium channel blockers (CCB) (OR: 4.1, P: 0.01). Conclusions. Aging and taking CCB were the only two major predictors for ED but surprisingly other metabolic or sexual covariates in this study did not have predictive value for ED risk in T2DM patients.


2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Ganesh N. Dakhale ◽  
Harshal V. Chaudhari ◽  
Meena Shrivastava

No study has ever examined the effect of vitamin C with metformin on fasting (FBS) and postmeal blood glucose (PMBG) as well as glycosylated hemoglobin (HbA1c) in the treatment of type 2 diabetes mellitus (DM). The goal was to examine the effect of oral vitamin C with metformin on FBS, PMBG, HbA1c, and plasma ascorbic acid level (PAA) with type 2 DM. Seventy patients with type 2 DM participated in a prospective, double-blind, placebo-controlled, 12-week study. The patients with type 2 DM were divided randomly into placebo and vitamin C group of 35 each. Both groups received the treatment for twelve weeks. Decreased PAA levels were found in patients with type 2 diabetes mellitus. This level was reversed significantly after treatment with vitamin C along with metformin compared to placebo with metformin. FBS, PMBG, and HbA1c levels showed significant improvement after 12 weeks of treatment with vitamin C. In conclusion, oral supplementation of vitamin C with metformin reverses ascorbic acid levels, reduces FBS, PMBG, and improves HbA1c. Hence, both the drugs in combination may be used in the treatment of type 2 DM to maintain good glycemic control.


2010 ◽  
Vol 30 (3) ◽  
pp. 186-190 ◽  
Author(s):  
Gustavo D. Pimentel ◽  
Kátia C. Portero-Mclellan ◽  
Érick P. Oliveira ◽  
Ana P.M. Spada ◽  
Marie Oshiiwa ◽  
...  

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