scholarly journals EATING DISORDERS IN PATIENTS WITH CHRONIC GASTRITIS AND TYPE 2 DIABETES MELLITUS

2019 ◽  
Vol 9 (4) ◽  
pp. 296-300
Author(s):  
D. D. Kazarin ◽  
A. E. Shklyaev ◽  
Yu. V. Gorbunov

Diabetes mellitus holds one of the leading positions among the current problems of modern medicine. Despite the obvious success in studying diabetes in the last decades, its prevalence has become pandemic. In spite of the use of modern methods of therapy, a rather high frequency of diabetes mellitus complications from various organs and systems, the pathological changes in which largely determine the course of the disease and patient’s quality of life remains. Issues of eating disorders and their correction play an important role in the complex therapy of patients with diabetes mellitus. Objective: determination of the characteristics and relationship of eating disorders with gastroenterological symptoms and glucose levels in patients with chronic gastritis in type 2 diabetes. Materials and methods: dynamic study of the eating behavior and quality of life in 66 patients with chronic gastritis in type 2 diabetes mellitus was conducted using GSRS, SF-36 and DEBQ questionnaires. The level of glucose on an empty stomach and after eating was also measured, the frequency of self-measurement of glucose level and the presence of diabetes mellitus complications were determined. Results: the identified correlation relationships suggest that gastrointestinal symptoms characteristic of chronic gastritis with type 2 diabetes mellitus worsen the physical and psychological components of health, which provokes a breakdown and a violation of the diet in this category of patients. Conclusion: chronic gastritis in patients with type 2 diabetes mellitus aggravates the prognosis of diabetes and exacerbates eating disorders, which requires observation of an endocrinologist, as well as a gastroenterologist and psychotherapist in the management of such patients.

2020 ◽  
Vol 5 (6) ◽  
pp. 170-175
Author(s):  
Y. S. Sirchak ◽  
◽  
S. V. Patskun

Diabetic neuropathies are the most common chronic complications of diabetes. This heterogeneous group of diseases affects different parts of the nervous system and has different clinical manifestations. Due to the lack of treatments aimed at repairing damaged nerves, prevention is a key component of the treatment of diabetic neuropathy. The purpose of the study was to assess the psychoemotional status of patients with type 2 diabetes mellitus and chronic gastritis and its relationship to serum ghrelin and magnesium ions. Material and methods. 77 patients were examined on the basis of the endocrinology department of Municipal Non-Commercial Enterprise "Transcarpathian Regional Clinical Hospital named after Andriy Novak". Their average age was 59.7 ± 4.1 years. This study was conducted with 41 (53.2%) women and 36 (46.8%) men. All patients were diagnosed with type 2 diabetes mellitus and chronic gastritis. All patients were surveyed using the following questionnaires: Quality of Life Questionnaire - Diabetic Neuropathy version (QOL-DN), Peripheral Neuropathy Quality-of-Life Instrument-97 (PN-QOL-97) and Pittsburgh Sleep Quality Index (PSQI). All patients underwent an objective examination by a podiatrist to assess the sensitivity and pulsation in the arteries of the feet. Serum ghrelin levels were determined by enzyme-linked immunosorbent assay using the Human Ghrelin ELISA Kit from RayBiotech No. 1.03930005306. Determination of serum magnesium levels was performed by colorimetry, the units are mmol / l. The normal value of magnesium levels was considered to be 0.66-1.07 mmol / l. All patients received combination therapy. Results and discussion. According to our study, the use of iDPP-4 in the treatment of type 2 diabetes and chronic gastritis not only promotes better glycemic control, but also to some extent improves the psychological state of patients with type 2 diabetes and hC, on the background of adequate hypoglycemic therapy and correction of magnesium deficiency using alpha-lipoic acid and B vitamins. After treatment, the average level of magnesium in the blood was from 0.31 ± 0.12 mmol / l in patients with type 2 diabetes and chronic gastritis increased to 0.68 ± 0.17 mmol / l (p <0.05). As for quality of life, significantly more improvement was obtained in group I, although the treatment of hypomagnesemia and diabetic polyneuropathy was carried out in one scheme, the only indicator that became different significantly after treatment with IDPP-4 was ghrelin, because there is an opinion about stress-protective effects of ghrelin. it can be assumed that its approximation to the norm may contribute to a better course of the disease. Conclusion. Combination therapy with hypoglycemic agents, including i-DPP-4, alpha-lipoic acid, B vitamins, magnesium antistress in patients with type 2 diabetes and chronic gastritis led to an improvement in the psychological state against the background of normal blood sugar levels


Medicina ◽  
2009 ◽  
Vol 45 (2) ◽  
pp. 85 ◽  
Author(s):  
Lina Lašaitė ◽  
Jūratė Lašienė ◽  
Gintautas Kazanavičius ◽  
Antanas Goštautas

The aim of the study was to evaluate associations of emotional state and quality of life with lipid concentration, duration of the disease, and the way of treating the disease in males and females with type 2 diabetes mellitus. A total of 53 persons with type 2 diabetes mellitus (27 males and 26 females; mean age, 58.7±8.9 years) and 56 healthy persons (26 males and 30 females; mean age, 54.7±8.3 years) participated in the study. Emotional state was evaluated by means of Profile of Mood State and quality of life by means of WHO Brief Quality of Life Questionnaire. Emotional state and quality of life were significantly worse, tension-anxiety and fatigue-inertia were significantly higher, vigor-activity was significantly lower in male patients with type 2 diabetes mellitus than in healthy males. In females, no significant differences in emotional state and quality of life comparing type 2 diabetes mellitus group and controls were detected. In females with type 2 diabetes mellitus, emotional state and quality of life were significantly better, scores of tension-anxiety, depression dejection, anger-hostility, and fatigue-inertia were significantly lower, and score of vigor-activity was significantly higher than in males with type 2 diabetes mellitus. Some significant correlations were found. In males, vigor-activity correlated with total cholesterol level and negatively correlated with triglyceride level. In females, significant correlations were found between scores of emotional state (tension-anxiety, depression-dejection, confusion-bewilderment, and total score of emotional state) and lipid levels (total cholesterol, triglyceride, and low-density lipoprotein cholesterol levels). There were no significant associations of emotional state and quality of life with duration of the disease in males and females with type 2 diabetes mellitus. No significant differences in emotional state and quality of life were found between males and females with type 2 diabetes mellitus, who were treated with oral antidiabetic preparations and insulin preparations.


2021 ◽  
Vol 25 (5) ◽  
pp. 432
Author(s):  
ManashP Baruah ◽  
Ananya Bhowmick ◽  
Seema Bhuyan ◽  
SonaliB Bhuyan ◽  
Jumi Deka ◽  
...  

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