A Review of Obstructive Sleep Apnea, Shift Work, Gender

2018 ◽  
Vol 1 (02) ◽  
Author(s):  
Chen Zuo ◽  
Joshua Jefferson

The purpose of the review is to make connections between obstructive sleep apnea (OSA) and shift work while giving special attention to the factor of gender and rapid eye movement sleep. Obstructive sleep apnea is a common sleep disorder that has various detrimental effects on health and cognitive functioning. The prevalence and symptoms of OSA appear to be gender specific. The current clinical guideline has not yet included the evaluation of fatigue, the common symptoms among women with OSA, which may lead to an under diagnosis of OSA among women. Rapid eye movement sleep is associated with more severe OSA episodes. Shift work has a similar range of effects on health and cognitive functioning, however, it affects workers through both sleep disturbance and circadian disruption. Gender specific effects have also been observed among shift workers. Night shift interacts with REM sleep and may lead to a higher risk of cardiovascular disease. Finally, we proposed the question, “Is there a difference in the REM sleep of male and female night shift workers with OSA,” and “How is cognitive functioning of these two groups affected by the interaction of OSA and shift work?”.

2018 ◽  
Vol 3 (03) ◽  
Author(s):  
Chen Zuo ◽  
Felicia Jefferson

The purpose of the review is to make connections between obstructive sleep apnea (OSA) and shift work while giving special attention to the factor of gender and rapid eye movement sleep. Obstructive sleep apnea is a common sleep disorder that has various detrimental effects on health and cognitive functioning. The prevalence and symptoms of OSA appear to be gender specific. The current clinical guideline has not yet included the evaluation of fatigue, the common symptoms among women with OSA, which may lead to an under diagnosis of OSA among women. Rapid eye movement sleep is associated with more severe OSA episodes. Shift work has a similar range of effects on health and cognitive functioning, however, it affects workers through both sleep disturbance and circadian disruption. Gender specific effects have also been observed among shift workers. Night shift interacts with REM sleep and may lead to a higher risk of cardiovascular disease. Finally, we proposed the question, “Is there a difference in the REM sleep of male and female night shift workers with OSA,” and “How is cognitive functioning of these two groups affected by the interaction of OSA and shift work?”.


CHEST Journal ◽  
2009 ◽  
Vol 135 (4) ◽  
pp. 957-964 ◽  
Author(s):  
Danny J. Eckert ◽  
Atul Malhotra ◽  
Yu L. Lo ◽  
David P. White ◽  
Amy S. Jordan

Sleep Science ◽  
2017 ◽  
Vol 10 (4) ◽  
pp. 134-141 ◽  
Author(s):  
Selene Verde-Tinoco ◽  
Rafael Santana-Miranda ◽  
Romel Gutiérrez-Escobar ◽  
Reyes Haro ◽  
Joana Miranda-Ortiz ◽  
...  

Neurosurgery ◽  
2004 ◽  
Vol 54 (3) ◽  
pp. 764-769 ◽  
Author(s):  
William C. Hanigan ◽  
Sarah N. Zallek

Abstract OBJECTIVE This report describes two shunted patients evaluated with continuous intracranial pressure (ICP) monitors for worsening headaches and subsequently diagnosed with obstructive sleep apnea. CLINICAL PRESENTATION AND INTERVENTION ICPs were monitored with strain-gauge sensors inserted into the frontal cortex. After the initial diagnosis of sleep apnea, 8-hour attended polysomnography was performed in each patient. Both patients showed apnea-hypopnea indices greater than 15. Consequently, a “split-night study” was performed to evaluate treatment with titrated nasal continuous positive airway pressure. Patient 1 was a 42-year-old woman (body mass index, 34.1) with a 16-year history of idiopathic intracranial hypertension treated with lumboperitoneal and ventriculoperitoneal shunts. Patient 2 was a 20-year-old man (body mass index, 64.4) with the Arnold-Chiari II malformation. The patient had had a low-pressure shunt since birth. Neurological examinations were normal or unchanged before evaluation. Neurophthalmological examinations were normal. Computed tomographic scans failed to show progressive ventriculomegaly. Awake ICPs were less than 15 mm Hg. Nighttime ICPs during rapid eye movement sleep showed multiple Lundberg A waves associated with obstructive sleep apnea and hypoxemia. Blood pressure did not change during these episodes. Polysomnography showed apnea-hypopnea indices of 31 and 41, respectively. Continuous positive airway pressure reduced apnea-hypopnea indices to 17 and 0, respectively; headaches resolved with outpatient therapy. CONCLUSION These observations suggest adequate shunting with reduced cerebral compliance in both patients. Altered respiratory mechanics associated with hypoxemia may have triggered cerebral vasodilation and increases in cerebral blood volume, particularly during rapid eye movement sleep. In noncompliant systems, these changes precipitated sustained elevations in ICP and intermittent headaches relieved by continuous positive airway pressure. The clinical patterns also suggest that obstructive sleep apnea should be considered in shunted patients with isolated symptoms of increasing headaches.


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