scholarly journals Incidence and Determinants of Health Care Associated Blood Stream Infection at a Neonatal Intensive Care Unit in Ujjain, India: A Prospective Cohort Study

2018 ◽  
Author(s):  
Mamta Dhaneria ◽  
Sachin Jain ◽  
Poonam Singh ◽  
Aditya Mathur ◽  
Cecilia Stålsby Lundborg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Blood Stream Infection ◽  
Blood Stream ◽  
Preterm Neonates ◽  
Resource Limited Settings ◽  
Resource Limited ◽  
Incidence Risk

Very little is known about laboratory confirmed blood stream infections (LCBIs) in neonatal intensive care units (NICUs) in resource-limited settings. The aim of this cohort study was to determine the incidence, risk factors, and causative agents of LCBIs in a level-2 NICU in India. The diagnosis of LCBIs was established using the Centre for Disease Control, USA criteria. A predesigned questionnaire containing risk factors associated with LCBIs was filled-in. A total of 150 neonates (43% preterm) were included in the study. The overall incidence of LCBIs was 31%. The independent risk factors for LCBIs were: preterm neonates (relative risk (RR) 2.23), duration of NICU stay more than 14 days (RR 1.75), chorioamnionitis in the mother (RR 3.18), premature rupture of membrane in mothers (RR 2.32), neonate born through meconium-stained amniotic fluid (RR 2.32), malpresentation (RR 3.05), endotracheal intubation (RR 3.41), umbilical catheterization (RR 4.18), and ventilator-associated pneumonia (RR 3.17). The initiation of minimal enteral nutrition was protective from LCBIs (RR 0.22). The predominant causative organisms were gram-negative pathogens (58%). The results of the present study can be used to design antibiotic interventions to reduce LCBIs in resource-limited settings.

scholarly journals Incidence and Determinants of Health Care Associated Blood Stream Infection at a Neonatal Intensive Care Unit in Ujjain, India: A Prospective Cohort Study

2017 ◽  
Author(s):  
Mamta Dhaneria ◽  
Sachin Jain ◽  
Poonam Singh ◽  
Aditya Mathur ◽  
Cecilia Stålsby Lundborg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Late Onset ◽  
Blood Stream Infection ◽  
Blood Stream ◽  
Extended Spectrum Beta Lactamase ◽  
Medical College ◽  
Resource Limited ◽  
Causative Agents

Very little is known about healthcare-associated infections (HAIs) in neonatal intensive care units (NICUs) in resource-limited settings including, India. The aim of this prospective study was to determine the prevalence, onset, risk factors and causative agents of laboratory confirmed blood stream (LBCI) as a HAI in a level-2 NICU at RD Gardi Medical College, Ujjain, India. The diagnosis of HAI was established using the Centre for Disease Control, USA criteria. A predesigned questionnaire containing risk factors associated with BSHAI was filled. A total of 150 neonates (43% preterm) were included in the study. The incidence of LBCI was 31%; 56% of which was late onset sepsis. The independent risk factors for LBCI were: preterm (Odds Ratio OR 3.22), duration of NICU stay more than 14 days (OR 2.38), chorioamnionitis in the mother (OR 18.48), neonate born through meconium stained amniotic fluid (OR 4.53), mal-presentation (OR 10.58), endotracheal intubation (OR 11.60), umbilical catheterization (OR 15.11), HAI due to ventilator-associated pneumonia (VAP) (OR 11.88). Initiation of minimal enteral nutrition was protective (OR 0.15). The predominant causative organisms were Gram-negative pathogens (58%). Among Klebsiella spp. and E. coli isolates, 73 and 80%, respectively were identified as extended-spectrum beta-lactamase producers. The results can be used to identify high-risk neonates for LBCI.

The Chasm in Neonatal Outcomes in Relation to Time of Birth in Lebanon

2007 ◽  
Vol 26 (2) ◽  
pp. 97-102 ◽  
Author(s):  
Lina Kurdahi Badr ◽  
Bahia Abdallah ◽  
Sossi Balian ◽  
Hala Tamim ◽  
Mirvat Hawari
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Night Shift ◽  
Neonatal Intensive Care Units ◽  
Maternal Risk Factors ◽  
Mortality And Morbidity ◽  
Maternal Risk ◽  
The Relationship

Purpose:The purpose of this study was to investigate the relationship between the time of birth and the mortality and morbidity of infants admitted to neonatal intensive care units.Design:This prospective, cohort study examined the records of women and infants admitted to the NICUs of four hospitals in Beirut, Lebanon, between July 1, 2002, and June 30, 2003. The hospitals selected were university affiliated and had a large number of deliveries (5,152 total for the year 2002–2003).Main Outcome Variables:Neonatal mortality and morbidity for infants admitted to the NICU were evaluated in relation to time of birth.Results:For the whole sample, mortality was higher for infants born during the night shift than for those born during the day shift. Mortality, morbidity, and brain asphyxia rates were also higher for infants born during the night shift and admitted to the NICU. Maternal risk factors and delivery complications were not consistently higher on the night shift.

Readmission to the Intensive Care Unit: Incidence, Risk Factors, Resource Use, and Outcomes. A Retrospective Cohort Study

2017 ◽  
Vol 14 (8) ◽  
pp. 1312-1319 ◽  
Author(s):  
Carolina R. Ponzoni ◽  
Thiago D. Corrêa ◽  
Roberto R. Filho ◽  
Ary Serpa Neto ◽  
Murillo S. C. Assunção ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Cohort Study ◽  
Intensive Care ◽  
Resource Use ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Incidence Risk

Investigation and Control of an Outbreak of Enterobacter aerogenes Bloodstream Infection in a Neonatal Intensive Care Unit in Fiji

2009 ◽  
Vol 30 (8) ◽  
pp. 797-800 ◽  
Author(s):  
Swastika A. Narayan ◽  
Jacob L. Kool ◽  
Miriama Vakololoma ◽  
Andrew C. Steer ◽  
Amelita Mejia ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Normal Saline ◽  
Neonatal Intensive Care ◽  
Blood Stream Infection ◽  
Enterobacter Aerogenes ◽  
Blood Stream ◽  
Single Use ◽  
And Control

Ten neonates developed blood stream infection with extended-spectrum β-lactamase-producing Enterobacter aerogenes in a neonatal intensive care unit in Fiji. The source of the outbreak was traced to a bag of contaminated normal saline in the ward, which was used for multiple patients. All isolates recovered from patients were indistinguishable from the bacteria recovered from the normal saline by pulsed-field gel electrophoresis. The outbreak was controlled using simple infection control practices such as reinforcement of strict hand hygiene policy, provision of single use vials of normal saline, and strict aseptic technique for injections.

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