scholarly journals Evidence for the Presence of Synovial Sheaths Surrounding the Extensor Tendons at the Metacarpophalangeal Joints

2021 ◽  
Author(s):  
Yousra Dakkak ◽  
Friso Jansen ◽  
Lambertus Wisse ◽  
Monique Reijnierse ◽  
Annette van der Helm-van Mil ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Synovial Tissue ◽  
Microscopy Study ◽  
Extensor Digitorum ◽  
Synovial Lining ◽  
Metacarpophalangeal Joints ◽  
Extensor Tendons ◽  
Increased Risk ◽  
Anatomic Variants ◽  
Fibroblast Like Synoviocytes

Background. MRI-detected inflammation around the metacarpophalangeal (MCP-)joints is prevalent in RA and poses a markedly increased risk of RA-development when present in arthralgia patients. Such inflammation is called ‘peritendinitis’, since anatomy literature reports no presence of a tenosynovial sheath at these tendons. However, the presence or absence of a synovial sheath at these extensor tendons has never been studied. Methods. A macroscopy and microscopy study of extensor-tendons at the MCP-joints of two embalmed human hands was performed. Routine histology was performed with Haematoxylin-Eosin staining. Results. We found evidence for the presence of synovial lining around extensor-tendons at MCP-joints. A delimited space surrounding the extensor digitorum tendon was observed, which was lined with an epithelium representing fibroblast-like synoviocytes. Conclusion. Contrast-enhancement around extensor tendons at MCP joints observed on MRI in RA represents tenosynovitis and thus inflammation of synovial tissue. Further studies with larger numbers of specimen are warranted to study anatomic variants. In addition, the molecular composition of the tenosynovium remains to be characterized.

SPONTANEOUS ULNAR DISLOCATION OF THE INDEX, LONG, RING AND SMALL FINGER EXTENSOR TENDONS AT THE METACARPOPHALANGEAL JOINTS: A CASE REPORT

Hand Surgery ◽  
2011 ◽  
Vol 16 (02) ◽  
pp. 193-196 ◽  
Author(s):  
Katsuhisa Tanabe ◽  
Takaya Nakajima ◽  
Eiji Sogo
Keyword(s):  
Rheumatoid Arthritis ◽  
Congenital Anomaly ◽  
Case Report ◽  
Extensor Tendon ◽  
Metacarpophalangeal Joint ◽  
Extensor Digitorum ◽  
Extensor Digitorum Communis ◽  
Metacarpophalangeal Joints ◽  
Extensor Tendons

Finger extensor tendon dislocation at the metacarpophalangeal joint is caused by various etiologies, such as trauma, congenital anomaly, or rheumatoid arthritis. When the dislocation occurs with no etiology, this is called spontaneous dislocation. Although spontaneous extensor tendon dislocation in one, two or three fingers has been described, to our knowledge, simultaneous dislocation in four fingers has not been reported. In this paper, we report a spontaneous ulnar dislocation of all the extensor tendons in the index, long, ring, and small fingers. Repair of the radial sagittal bands of the extensor digitorum communis of the middle and ring fingers reduced dislocation of all the extensor tendons in four fingers.

scholarly journals Bilateral anatomical variations of the hand extensors

2016 ◽  
Vol 15 (2) ◽  
pp. 278-282
Author(s):  
Humberto Ferreira Arquez
Keyword(s):  
Anatomical Variation ◽  
Medical Science ◽  
Ring Finger ◽  
Anatomical Variations ◽  
Extensor Digitorum ◽  
Left Hand ◽  
Extensor Tendons ◽  
Right Hand ◽  
The Right ◽  
Little Finger

Background: The purpose of this paper is to describe an anatomical variation of the hand extensor on the little finger of the right hand which receives four tendons, condition unknown, as it is the first case reported so far in the literature. The human extensor tendons of hand often display an array of variations. Awareness of the anatomy and variations of the extensor tendons on the dorsum of the hand is necessary not only for the anatomist but also for surgeons when considering tendons for hand surgery, tendon rerouting or transplants. Materials and Methods: Bilateral anatomical variation in the upper limb was found during routine dissection in a 75-year-old male cadaver in the Morphology Laboratory at the University of Pamplona. The variations were recorded and photographed. Result: In the left hand the extensor digitorum there was a single tendon to the index, double tendon to the middle, triple tendon to the ring finger, a single tendon to the little finger or digiti minimi. The extensor digiti minimi has double tendon. In the right hand the extensor digitorum there was a single tendon to the index, triple tendon to the middle finger, triple tendons to the ring finger, a double tendon to the little finger. The extensor digiti minimi has double tendon. The little finger receives four tendons, 2 of extensor digitorum and 2 of extensor digiti minimi. The dorsum of the left hand and right showed juncturae tendinum type 2, between the extensors tendons in the 3rd intermetacarpal space; type 3, between the extensors tendons in the 4th inter metacarpal space. Conclusion: The presence of multiple tendons may alter the kinematics around the site of attachment to the phalanx. Knowledge of anatomical variations and normal anatomy of the extensor tendons, may be helpful while performing graft and tendon transfer operations.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.278-282

scholarly journals Duplication of the Extensor Pollicis Longus and Index Extensor Digitorum Communis: Report of a Novel Anomaly and Review of Literature

2021 ◽  
Vol 7 ◽  
pp. 2513826X2110479
Author(s):  
BaiJing Qin ◽  
David T. W. Chiu ◽  
Charles P. Melone
Keyword(s):  
Index Finger ◽  
Elective Surgery ◽  
Extensor Digitorum ◽  
Extensor Digitorum Communis ◽  
Review Of Literature ◽  
Extensor Pollicis Longus ◽  
Cadaveric Dissection ◽  
Extensor Tendons ◽  
Extensor Compartment

Accessory extensor tendons in the hand are not rare, usually asymptomatic, and recognized incidentally during elective surgery or cadaveric dissection. This report describes a novel case of symptomatic duplication of accessory extensor tendons to both the thumb and the index finger causing a painful dorsal wrist tenosynovitis. Excision of the accessory tendons with decompression and tenosynovectomy of the fourth extensor compartment alleviated the patient’s symptoms without compromising motion or function.

Atomic Force Microscopy Study of the Anti-inflammatory Effects of Triptolide on Rheumatoid Arthritis Fibroblast-like Synoviocytes

2017 ◽  
Vol 23 (5) ◽  
pp. 1002-1012 ◽  
Author(s):  
Zhanhui Su ◽  
Han Sun ◽  
Man Ao ◽  
Chunying Zhao
Keyword(s):  
Rheumatoid Arthritis ◽  
Atomic Force Microscopy ◽  
Inflammatory Responses ◽  
Bone Destruction ◽  
Microscopy Study ◽  
Primary Role ◽  
Force Microscopy ◽  
Atomic Force ◽  
Anti Inflammatory ◽  
Fibroblast Like Synoviocytes

AbstractHigh-resolution atomic force microscopy (AFM) was used for the in situ evaluation of the anti-inflammatory effects of triptolide on rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) to understand the anti-RA effects of triptolide, based on the morphological and biophysical changes observed in RA-FLS. RA-FLS have been reported to play a primary role in inflammatory bone destruction during the development of RA and thus are regarded as an important target for RA treatment. Triptolide pretreatment significantly inhibited tumor necrosis factor-α-induced expression of the interleukin (IL)-1β, IL-6, and IL-8 genes in MH7A cells. Using AFM, we showed that triptolide-induced morphological damage in MH7A cells by inducing significant ultrastructure changes in the membrane, which were closely related to triptolide-induced apoptosis in MH7A cells. Using force measurements determined with AFM, triptolide was shown to increase the stiffness of MH7A cells. These findings not only revealed the strong anti-inflammatory effects of triptolide on RA-FLS, highlighting triptolide as a potential anti-RA agent, but also revealed the possible use of AFM for studying anti-inflammatory responses in RA-FLS, which we expect to be developed into a potential tool for anti-RA drug studies in RA-FLS.

scholarly journals The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis

2011 ◽  
Vol 13 (2) ◽  
Author(s):  
Anna-Karin H Ekwall ◽  
Thomas Eisler ◽  
Christian Anderberg ◽  
Chunsheng Jin ◽  
Niclas Karlsson ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Synovial Lining ◽  
Fibroblast Like Synoviocytes

Spontaneous Dislocation of the Extensor Tendons with Flexion and Ulnar Deviation Contracture of the Metacarpophalangeal Joint: A Case Report

Hand Surgery ◽  
2003 ◽  
Vol 08 (01) ◽  
pp. 97-101
Author(s):  
Masaharu Makino
Keyword(s):  
Case Report ◽  
Extensor Tendon ◽  
Metacarpophalangeal Joint ◽  
Ulnar Deviation ◽  
Metacarpophalangeal Joints ◽  
Extensor Tendons ◽  
Right Hand ◽  
Intrinsic Muscles

A case with spontaneous extensor tendon dislocation was treated operatively. Right hand was more severely affected with contracture of the metacarpophalangeal joints. Centralisation of the extensor tendons and sectioning of ulnar intrinsic muscles sufficed correction of the pathology. No recurrence occurred in the last 24 months.

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