scholarly journals Inhibitory Smads suppress pancreatic stellate cell activation through negative feedback in chronic pancreatitis

2021 ◽  
Vol 9 (5) ◽  
pp. 384-384
Author(s):  
Hao Lin ◽  
Beibei Dong ◽  
Liang Qi ◽  
Yingxiang Wei ◽  
Yusha Zhang ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Negative Feedback ◽  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell

Mo1381 ROLE OF IL-17A IN THE PATHOGENESIS OF CHRONIC PANCREATITIS AND PANCREATIC STELLATE CELL ACTIVATION.

2020 ◽  
Vol 158 (6) ◽  
pp. S-869-S-870
Author(s):  
Mohammad Tarique ◽  
Srikanth Iyer ◽  
Ejas Palathingal Bava ◽  
Preeti Sahay ◽  
Rajinder Dawra ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell

The influence of alcohol and cigarette smoke components on pancreatic stellate cell activation: Implications for the progression of chronic pancreatitis

Pancreatology ◽  
2014 ◽  
Vol 14 (3) ◽  
pp. S18-S19
Author(s):  
Zhihong Xu ◽  
Alexandra Lee ◽  
Srinivasa Pothula ◽  
Mishaal Patel ◽  
Romano Pirola ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Cigarette Smoke ◽  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell

Fibrogenesis in the Pancreas after Acinar Cell Injury

2005 ◽  
Vol 94 (2) ◽  
pp. 108-111 ◽  
Author(s):  
M. Patel ◽  
D. R. Fine
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Cell Activation ◽  
Cell Injury ◽  
Stellate Cell ◽  
Acinar Cells ◽  
Signalling Pathways ◽  
Phenotypic Change ◽  
Current Interest ◽  
Pancreatic Stellate Cell

Fibrosis within the pancreas is a key feature of chronic pancreatitis and pancreatic cancer. It has now been well demonstrated that following injury to acinar cells, pancreatic stellate cell activation, migration and proliferation is the key mediator of this process. Many cytokines and growth factors have been studied, particularly TGF-β, which appears to be the major stimulus to fibrinogenesis. There is current interest in the mechanisms of phenotypic change between the active and quiescent forms, apoptosis and the signalling pathways that may be involved. The pancreatic stellate cell is likely to play an important role in maintaining the normal extracellular matrix; we speculate that the dysregulation of this process is an important factor in chronic pancreatitis.

SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis

2019 ◽  
Vol 384 (1) ◽  
pp. 111606 ◽  
Author(s):  
Peng Tan ◽  
Ankang Wang ◽  
Hao Chen ◽  
Yichao Du ◽  
Baolin Qian ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell

132 Galectin-3 Induces Human Pancreatic Stellate Cell Activation and IL-8 Production via NF-kB Signaling

2010 ◽  
Vol 138 (5) ◽  
pp. S-25
Author(s):  
Shumei Song ◽  
Xiaoyi Duan ◽  
Rosa F. Hwang ◽  
Margarete Hafley ◽  
Sushovan Guha ◽  
...  
Keyword(s):  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell ◽  
Galectin 3

scholarly journals Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer

2017 ◽  
Vol 140 (9) ◽  
pp. 2101-2111 ◽  
Author(s):  
Dannel Yeo ◽  
Phoebe Phillips ◽  
Graham S. Baldwin ◽  
Hong He ◽  
Mehrdad Nikfarjam
Keyword(s):  
Pancreatic Cancer ◽  
Cell Activation ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell ◽  
Group 1

T1891 The Urokinase System Plays a Critical Role in Pancreatic Stellate Cell Activation

2008 ◽  
Vol 134 (4) ◽  
pp. A-585
Author(s):  
Aurelia Lugea ◽  
Xiaomeng Wu ◽  
Dasari Srividya ◽  
Stephen J. Pandol
Keyword(s):  
Cell Activation ◽  
Stellate Cell ◽  
Critical Role ◽  
Pancreatic Stellate Cell ◽  
Urokinase System

The Role of Dendritic Cell and Pancreatic Stellate Cell Cross-Talk in Chronic Pancreatitis

2012 ◽  
Vol 172 (2) ◽  
pp. 223
Author(s):  
A.H. Nguyen ◽  
A.S. Bedrosian ◽  
M. Connolly ◽  
J. Henning ◽  
V. Medina-Zea ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Dendritic Cell ◽  
Cross Talk ◽  
Stellate Cell ◽  
Pancreatic Stellate Cell
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