Association between Dix-Hallpike test parameters and successful  repositioning maneuver in posterior semicircular canal benign  paroxysmal positional vertigo: a case-control study

Abstract Objectives This study aimed to evaluate serum otolin-1 levels in patients with benign paroxysmal positional vertigo and to compare these levels with healthy individuals. Method This was a case-control study. After obtaining institutional ethical committee clearance, the serum level of otolin-1 was calculated in adult individuals (18–75 years old) who were divided into group 1 (patients presenting with benign paroxysmal positional vertigo) and group 2 (healthy patients without benign paroxysmal positional vertigo as the control group). Data analysis was carried out to compare the serum levels in the cases and controls. A p-value less than 0.05 was considered significant. Results A total of 70 age-matched individuals (cases, n = 40; controls, n = 30) were included in the study. The mean serum level of otolin-1 was 636.8 pg/ml (range, 259–981 pg/ml) in the group of patients with benign paroxysmal positional vertigo and 236.2 pg/ml (range, 189–370 pg/ml) in the control group. The difference was statistically significant (p = 0.0000). Conclusion The serum levels of otolin-1 in patients with benign paroxysmal positional vertigo are significantly higher compared with individuals without benign paroxysmal positional vertigo.

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Osteoporosis increases the risk of benign paroxysmal positional vertigo: a nested case–control study using a national sample cohort

European Archives of Oto-Rhino-Laryngology ◽

10.1007/s00405-018-5230-y ◽

2018 ◽

Vol 276 (2) ◽

pp. 335-342 ◽

Cited By ~ 9

Author(s):

Hyo Geun Choi ◽

Joon Kyu Lee ◽

Il Gyu Kong ◽

Hyun Lim ◽

So Young Kim

Keyword(s):

Benign Paroxysmal Positional Vertigo ◽

Case Control Study ◽

National Sample ◽

Case Control ◽

Positional Vertigo ◽

Nested Case Control ◽

Control Study ◽

Paroxysmal Positional Vertigo

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Prevalence of benign paroxysmal positional vertigo among motocross racers: a case-control study

The Turkish Journal of Ear Nose and Throat ◽

10.5606/kbbihtisas.2015.90922 ◽

2015 ◽

Vol 25 (5) ◽

pp. 279-283

Author(s):

Deniz Hancı

Keyword(s):

Benign Paroxysmal Positional Vertigo ◽

Case Control Study ◽

Case Control ◽

Positional Vertigo ◽

Control Study ◽

Paroxysmal Positional Vertigo

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Particle Repositioning Maneuver for Benign Paroxysmal Positional Vertigo

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949310200501 ◽

1993 ◽

Vol 102 (5) ◽

pp. 325-331 ◽

Cited By ~ 142

Author(s):

Lorne S. Parnes ◽

R. Greg Price-Jones

Keyword(s):

Semicircular Canal ◽

Benign Paroxysmal Positional Vertigo ◽

Poor Response ◽

Posterior Semicircular Canal ◽

Positional Vertigo ◽

Lost To Follow Up ◽

Repositioning Maneuver ◽

Simple Bedside ◽

Paroxysmal Positional Vertigo

Benign paroxysmal positional vertigo is a common, most often self-limited, vestibular end organ disorder that in some cases may be quite disabling. Recent evidence suggests that some, if not most, cases result from free-floating posterior semicircular canal endolymph particles. We postulate that the particle repositioning maneuver displaces these particles from the posterior canal through the common crus into the utricle, where they no longer induce pathologic responses. Our report focuses on 38 consecutive patients treated with this simple bedside technique during a 10-month period. On follow-up, 26 patients (68.4%) were free of disease, 4 (10.5%) were significantly improved, 4 (10.5%) remained unchanged, and 4 (10.5%) were lost to follow-up. Of the 4 patients who remained unchanged, 2 underwent successful posterior semicircular canal occlusions. The direction of the nystagmus during the second stage of the maneuver appears important in predicting the efficacy, with reversal of nystagmus denoting a poor response. These findings provide additional insight into the pathophysiology of this disorder.

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Efficacy of Epley maneuver in treatment of benign paroxysmal positional vertigo of the posterior semicircular canal

Vojnosanitetski pregled ◽

10.2298/vsp1208669b ◽

2012 ◽

Vol 69 (8) ◽

pp. 669-674 ◽

Cited By ~ 3

Author(s):

Snezana Babac ◽

Nenad Arsovic

Keyword(s):

Success Rate ◽

Semicircular Canal ◽

Benign Paroxysmal Positional Vertigo ◽

Spontaneous Nystagmus ◽

Posterior Semicircular Canal ◽

Duration Of Symptoms ◽

Positional Vertigo ◽

Epley Maneuver ◽

Repositioning Maneuver ◽

Paroxysmal Positional Vertigo

Background/Aim. Benign paroxysmal positional vertigo is one of the most frequent peripheral vestibular system disorders. The aim of this study was to examine the efficacy of the Epley maneuver in treating benign paroxysmal positional vertigo of the posterior semicircular canal (p- BPPV) and to discover possible causes of failure. Methods. This prospective study included 75 patients. In all the cases medical history showed and the positioning Dix-Hallpike test confirmed the diagnosis of p-BPPV. We also performed clinical ENT examination, searching for spontaneous nystagmus, vestibulospinal tests, caloric test, and audiometry. All the patients were treated by the modified Epley canalith repositioning maneuver. The patients were followed up at the intervals of seven and, fourteen days, and one, tree, and six months and one year. The maneuver was repeated if vertigo and nystagmus on control positioning test persisted. The transition from positive into negative Dix Hallpike test after one or two Epley maneuver was considered as success in treatment. Results. After the initial Epley maneuver the recovery rate was 90.7%, and after the second 96%. In three (4%) patients with secondary p-BPPV, symptoms did not cease even after the second repositioning maneuver. The etiology of p-BPPV had a significant effect on the maneuver?s success rate (p < 0.01), whereas duration of symptoms, age and gender had no effect (p > 0.05). After a successful treatment 11 (14.66%) patients had recurrent attack of BPPV during the first year. Conclusion. The Epley maneuver is very successful repositioning procedure in treating p- BPPV. The patients with idiopathic form p-BPPV showed higher success rate with Epley maneuver than those with secondary p-BPPV.

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