Clinicopathological characteristics and treatment of young women with breast cancer in China: a nationwide multicenter 10-year retrospective study

Abstract Background: Breast cancer among young women is a rare pathology, but is known to have a more aggressive behavior and poorer outcome. Aims: The objective of this study was to evaluate the clinicopathological characteristics of breast carcinoma below 40 years in comparison to that over 40 years in Manipur, India. Settings and Design: This retrospective study from the period of January 2005-December 2010 was conducted in the Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur. Materials and Methods: All cases of mastectomy specimens of carcinoma breast from the period of January 2005-December 2010 were included in the study. Clinical and histopathological data of all cases were reviewed and correlated. Results: A total of 507 mastectomy specimens were received, among which, 160 cases (31.56%) were below 40 years; whereas 347 cases (68.44%) were above 40 years of age. Stage III was the commonest stage (47% versus 18%) in the younger group; while in the older group, Stage II was the commonest (64% versus 34%). Conclusion: This study shows that young females with breast cancer have higher stage of tumor.

Download Full-text

Amenorrhea, fertility preservation, and counseling among young women treated with anthracyclines and taxanes for early-stage breast cancer, a retrospective study

Medicine ◽

10.1097/md.0000000000019566 ◽

2020 ◽

Vol 99 (11) ◽

pp. e19566 ◽

Cited By ~ 1

Author(s):

Hikmat N. Abdel-Razeq ◽

Razan A. Mansour ◽

Khawla S. Ammar ◽

Rashid H. Abdel-Razeq ◽

Hadil Y. Zureigat ◽

...

Keyword(s):

Breast Cancer ◽

Retrospective Study ◽

Fertility Preservation ◽

Young Women ◽

Early Stage ◽

Early Stage Breast Cancer

Download Full-text

CERVICAL CANCER AMONG 39 YEARS OR YOUNGER FEMALES IN SOUTH INDIA; A RETROSPECTIVE STUDY

10.36106/ijsr/0700673 ◽

2021 ◽

pp. 15-17

Author(s):

B Ramkumar ◽

Srigopal Mohanty ◽

Kiranmayee Narapaneni ◽

Amit Saklani ◽

J Kannan

Keyword(s):

Cervical Cancer ◽

Retrospective Study ◽

Older Women ◽

Young Women ◽

Clinicopathological Characteristics ◽

Categorical Variables ◽

Chi Square ◽

Younger Women ◽

Ciency Virus ◽

Chi Square Test

Background: Cervical cancer in young women is rare and disparity exists in its characteristics in the available reports. The study aimed to determine the disease burden and to compare its clinicopathological characteristics with older women. Materials and methods: Retrospective study was performed by retrieving data from the cancer registry for consecutive 843 cervical cancer patients treated in the center between 2017 and 2020. Patients were divided into younger (<40 years) and older (≥ 40 years) age. Statistical analysis was performed using SPSS software version 23 for windows. Chi square test was used for analyzing the categorical variables and P < 0.05 was considered signicant. Results: Cervical cancer in young women constituted 9.4%, with majority (96.2%) belonged to 30-39 years age. Higher prevalence of human immunodeciency virus (HIV) was found among younger compared to older women (P = 0.000). Younger women commonly presented late compared to older women (patients presented after 4 months are 49.4% vs. 18.8% respectively, P=0.000). Squamous cell carcinoma was commonest histology in both the groups and no difference in histology pattern between the two groups. Younger women had higher rate of bulky tumor (>4cm) compared to older (62.2% vs. 44.4%, P = 0.023). Conclusion: Delayed and advanced stage of presentation of cervical cancer in younger women in this region of India warrants promotion of health education, knowledge translation, regular cervical cancer screening for its prevention and early detection

Download Full-text