Effectiveness of stent graft versus balloon angioplasty for failing arteriovenous dialysis graft—a single center retrospective cohort experience

The objective of this study was to determine if propofol administration to veno-venous (VV) extracorporeal membrane oxygenation (ECMO) patients was associated with more incidents of oxygenator failure when compared to patients who did not receive propofol. This was a single center, retrospective cohort study. The primary outcome of the study is oxygenator exchanges per ECMO day in patients who received propofol versus those who did not receive propofol. Patients were 18 years or older on VV-ECMO support between January 1, 2015 and January 31, 2018. Patients were excluded if they required ECMO support for less than 48 h or greater than 21 days. There were five patients in the propofol arm that required oxygenator exchanges and seven patients in the control arm. The total number of oxygenator exchanges per ECMO day was not significantly different between groups ( p = 0.50). When comparing those who required an oxygenator exchange and those who did not, there was no difference in the cumulative dose of propofol received per ECMO hour (0.64 mg/kg/h vs 0.96 mg/kg/h; p = 0.16). Propofol use in patients on VV-ECMO does not appear to increase the number of oxygenator exchanges.

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Twice weekly prophylaxis with trimethoprim/sulfamethoxazole for Pneumocystis jirovecii pneumonia in pediatric oncology patients

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155220979046 ◽

2020 ◽

pp. 107815522097904

Author(s):

Monica Awad ◽

Caroline M Sierra ◽

Elhaam Mesghali ◽

Khaled Bahjri

Keyword(s):

Pediatric Oncology ◽

Retrospective Cohort ◽

Hematologic Malignancies ◽

Primary Objective ◽

Pneumocystis Jirovecii ◽

Pneumocystis Jirovecii Pneumonia ◽

Weekly Dose ◽

Single Center ◽

Oncology Patients ◽

Prophylaxis Therapy

Current recommendations for prophylaxis of Pneumocystis jirovecii pneumonia in oncology patients include administration of trimethoprim/sulfamethoxazole (TMP/SMX) three times weekly or the same total weekly dose given daily. The primary objective of this study was to evaluate the efficacy of two consecutive days per week of TMP/SMX for prevention of Pneumocystis jirovecii pneumonia (PJP) in pediatric oncology patients. A retrospective cohort, single-center analysis was conducted in oncology patients 21 years and younger who received TMP/SMX for PJP prophylaxis between February 1, 2013 and July 31, 2017. Changes to the prophylaxis regimen were documented and analyzed. A total of 322 patients received TMP/SMX on two consecutive days per week for PJP prevention, of whom four had confirmed PJP (1.3%). Neutropenia was the most common reason for switching to alternative prophylaxis therapy (11.5%). Two consecutive prophylaxis days with TMP/SMX may be insufficient to prevent PJP in children with hematologic malignancies. Neutropenia remains a barrier for TMP/SMX use for PJP prophylaxis. Further studies to compare PJP incidence in children receiving alternative prophylaxis regimens should be considered.

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Evaluation of accuracy of laparoscopic liver mono‐segmentectomy using the Glissonian approach with indocyanine green fluorescence negative staining by comparing estimated and actual resection volumes: A single‐center retrospective cohort study

Journal of Hepato-Biliary-Pancreatic Sciences ◽

10.1002/jhbp.924 ◽

2021 ◽

Author(s):

Naotake Funamizu ◽

Takahiro Ozaki ◽

Kohei Mishima ◽

Kazuharu Igarashi ◽

Kenji Omura ◽

...

Keyword(s):

Cohort Study ◽

Indocyanine Green ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Negative Staining ◽

Single Center ◽

Green Fluorescence ◽

Indocyanine Green Fluorescence ◽

Glissonian Approach

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Epidemiology and Management of Children with Hypertensive Crisis: A Single-Center Experience

Journal of Pediatric Intensive Care ◽

10.1055/s-0039-1698759 ◽

2019 ◽

Vol 09 (01) ◽

pp. 045-050

Author(s):

Alicia May Lim ◽

Siew Le Chong ◽

Yong Hong Ng ◽

Yoke Hwee Chan ◽

Jan Hau Lee

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Hypertensive Crisis ◽

Hypertensive Emergency ◽

Renal Pathology ◽

Pediatric Hospital ◽

Single Center ◽

Single Center Experience ◽

Effective Treatments

AbstractMost children who present with hypertensive crisis have a secondary cause for hypertension. This study describes the epidemiology and management of children with hypertensive crisis. A retrospective cohort study was done in a tertiary pediatric hospital from 2009 to 2015. Thirty-seven patients were treated for hypertensive crisis. Twelve (32.4%) patients were treated for hypertensive emergency. The majority of our patients (33 [89.1%]) had a secondary cause of hypertension. The most common identifiable cause of hypertension was a renal pathology (18/37 [48.6%]). Oral nifedipine (23 [62.1%]) was the most frequently used antihypertensive, followed by intravenous labetalol (8 [21.6%]). There were no mortalities or morbidities. Hypertensive crisis in children is likely secondary in nature. Oral nifedipine and intravenous labetalol are both effective treatments.

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