AB138. 211. A study of vitamin D levels in a frail elderly hip fracture population and a comparative non-frail elderly population

2018 ◽  
Vol 2 ◽  
pp. AB138-AB138
Author(s):  
Evelyn Patricia Murphy ◽  
Robert Murphy ◽  
Padraic Murray
Keyword(s):  
Vitamin D ◽  
Hip Fracture ◽  
Frail Elderly ◽  
Elderly Population ◽  
Vitamin D Levels ◽  
Fracture Population

Vitamin D levels in frail elderly patients with a hip fracture

2013 ◽  
Vol 4 ◽  
pp. S63 ◽  
Author(s):  
M. Abildgaard Pedersen ◽  
M. Gregersen ◽  
B. Lomholt Langdahl ◽  
E.M. Skjøde Damsgaard
Keyword(s):  
Vitamin D ◽  
Hip Fracture ◽  
Elderly Patients ◽  
Frail Elderly ◽  
Vitamin D Levels

scholarly journals Coronavirus in HIP Fractures CHIP 2: Is Vitamin D Deficiency Associated with Increased Mortality from COVID-19 Infections in A Hip Fracture Population?

2021 ◽  
Vol 3 (6) ◽  
pp. 111-116
Author(s):  
A. Mahmood ◽  
F. Rashid ◽  
D. Hawkes ◽  
W. J. Harrison
Keyword(s):  
Vitamin D ◽  
Hip Fracture ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Primary Outcome Measure ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Fracture Population ◽  
The Impact ◽  
The Relationship

Purpose: There is controversy as to whether vitamin D deficiency is associated with increased mortality from coronavirus infection. The aim of the study was to assess the relationship between vitamin D levels and 30-day mortality in hip fracture patients co-infected with COVID-19. Methods: This was a national observational audit conducted between 23 March 2020 (start of UK lockdown) and 31st December 2020. The cohort consisted of patients aged >60 years presenting with a hip fracture. Patients were included if they had a vitamin D level done during the admission episode, diagnosis of COVID-19 infection via a viral reverse transcriptase PCR swab, and a hip fracture. There were 517 patients included in the study from 43 different hospital trusts. The primary outcome measure was 30-day mortality. Secondary outcomes were the percentage of patients who had vitamin D deficiency, the percentage of patients who were prescribed Vitamin D, and the impact of vitamin D prescribing on mortality Results: Vitamin D deficiency was not associated with a higher 30-day mortality. Low serum vitamin D was observed in 56% of the patients on admission. Vitamin D was prescribed prior to admission in 28% and during admission in a further 49%. Pre-hospital vitamin D therapy reduced the chance of vitamin D deficiency. Starting vitamin D before or on admission did not affect the mortality rates. Conclusion: Vitamin D deficiency was common, but not associated with a higher 30-day mortality in the hip fracture population co-infected with COVID-19.

Serum levels of 25(OH)D are not associated with venous thromboembolism in the elderly population

2016 ◽  
Vol 115 (01) ◽  
pp. 169-175 ◽  
Author(s):  
Aurélien Delluc ◽  
Marie-Pierre Moineau ◽  
Cécile Tromeur ◽  
Maelenn Gouillou ◽  
Karine Lacut ◽  
...  
Keyword(s):  
Vitamin D ◽  
Venous Thromboembolism ◽  
Seasonal Variations ◽  
Elderly Population ◽  
Serum Levels ◽  
The Elderly ◽  
Vitamin D Status ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Walking Capacity

SummaryThe prevalence of both vitamin D deficiency and venous thromboembolism (VTE) is important in the elderly. Previous studies have provided evidence for a possible association between vitamin D status and the risk of VTE. Thus, we aimed to investigate the association between vitamin D levels and VTE in the population aged 75 and over included in the EDITH case-control study. The association between vitamin D status and VTE was analysed. We also analysed the monthly and seasonal variations of VTE and vitamin D. Between May 2000 and December 2009, 340 elderly patients (mean age 81.5 years, 32 % men) with unprovoked VTE and their controls were included. The univariate and multivariate analysis found no significant association between serum levels of vitamin D and the risk of unprovoked VTE. In the unadjusted analysis, a higher BMI was statistically associated with an increased risk of VTE (OR 1.09; 95 % CI 1.05–1.13) whereas a better walking capacity and living at home were associated with a decreased rate of VTE: OR 0.57; 95 % CI 0.36–0.90 and 0.40; 95 % CI 0.25–0.66, respectively. Although not significant, more VTE events occurred during winter (p=0.09). No seasonal variations of vitamin D levels were found (p=0.11). In conclusion, in contrast with previous reports our findings suggest that vitamin D is not associated with VTE in the elderly population.

scholarly journals Vitamin D Levels and Nutritional Risk Index: Mobility and Mortality After Hip Fracture Surgery (P01-013-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Lihong Hao ◽  
Yvette Schlussel ◽  
Jeffrey Carson ◽  
Sue Shapses
Keyword(s):  
Vitamin D ◽  
Hip Fracture ◽  
Vitamin D Deficiency ◽  
Risk Index ◽  
Nutritional Risk ◽  
Walking Ability ◽  
Hip Fracture Surgery ◽  
Vitamin D Levels ◽  
Nutritional Risk Index ◽  
Fracture Surgery

Abstract Objectives Hip fractures are associated with a high rate of morbidity and mortality, and successful ambulation after surgery is an important outcome in this patient population. This study aims to determine whether 25-hydroxyvitamin D (25(OH)D) or the Geriatric Nutritional Risk Index (GNRI) is associated with short term mortality or ability to walk after hip fracture surgery. Methods Patients undergoing hip fracture repair were included in this study. Mortality and walking ability were assessed at 30 and 60 days after hip fracture surgery. Pre-operative serum albumin and 25(OH)D were measured. Patients were characterized with 25(OH)D <12 ng/mL, 12 to <20, 20 to <30 or ≥30. GNRI was calculated from albumin and body weight and patients were categorized into major/moderate nutritional risk (<92), low risk (92 to <98) or in good nutritional status (≥98). Results Of the 290 patients (82 ± 7 years, BMI 25 ± 5 kg/m2), 73% were females. Compared to patients with vitamin D deficiency (<12 ng/mL), those with vitamin D levels in higher categories had increased ability to walk at 30 days (P = 0.031): 12 to <20 ng/ml (adjusted odds ratio = 2.61; 95% confidence interval = 1.13–5.99); 20 to <30 ng/ml (3.48; 1.53–7.95); ≥30 ng/ml (2.84; 1.12–7.20). In addition, patients also had increased mobility at 60 days in these same higher vitamin D categories 12 to <20 (2.67; 1.14–6.25); 20 to <30 (3.42; 1.46–8.00); ≥30 ng/ml (3.67; 1.37–9.82) compared to the reference group (<12 ng/mL; P = 0.028). There was no association of vitamin D with mortality at either time point. GNRI was not associated with mortality or walking ability. Conclusions In patients with hip fracture, vitamin D deficiency (<12 ng/mL) was associated with reduced ambulation after surgery, whereas GNRI was not associated with any outcomes. Mechanisms that attenuate mobility due to vitamin D deficiency should be examined in future studies. Funding Sources ONE Nutrition Grant to SAS and JLC.

scholarly journals Which factors are associated with sarcopenia and frailty in elderly persons residing in the community?

2018 ◽  
Vol 21 (6) ◽  
pp. 755-766
Author(s):  
Ana Paula Pillatt ◽  
Rutiana Silva Patias ◽  
Evelise Moraes Berlezi ◽  
Rodolfo Herberto Schneider
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Frail Elderly ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Elderly Persons ◽  
Risk Of Death ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Low Serum

Abstract Objective: to broaden knowledge about the factors associated with sarcopenia and frailty in elderly persons residing in the community. Method: an integrative systematic review based on the PRISMA recommendations was carried out, using articles published from 2012 to March 2017 in the PubMED, SciELO, Virtual Health Library, CINAHL and Springer electronic databases with the following descriptors: frail elderly, sarcopenia and etiology and their synonyms. The articles identified by the initial search strategy were independently assessed by two researchers, according to the eligibility criteria, and the articles selected were evaluated for methodological quality. Results: the results of this survey show that frailty may be associated with sarcopenia, low serum vitamin D levels, anemia, subclinical hyperthyroidism in men, while the greatest evolution in women was for osteoporosis. An association between sarcopenia and advanced age was also observed, with worsening quality of life, physical-functional capacity, nutritional status and comorbidities, as well as an increased risk of death in sarcopenic elderly persons. Conclusion: this systematic review showed that low serum levels of vitamin D are associated with frailty and factors that predispose this condition. It is therefore important to monitor the serum levels of this vitamin in the elderly population, and it is suggested that new studies are carried out related to supplements of this vitamin in frail elderly persons.

scholarly journals Bone biopsies and serum vitamin-D levels in patients with hip fracture

1989 ◽  
Vol 60 (4) ◽  
pp. 411-413 ◽  
Author(s):  
Itamar Eventov ◽  
Bertha Frisch ◽  
Doron Alk ◽  
Zipora Eisenberg ◽  
Yosef Weisman
Keyword(s):  
Vitamin D ◽  
Hip Fracture ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Bone Biopsies

scholarly journals The Association Between Hypovitaminosis D Status with Muscle Strength and Functional Capacity in a Brazilian Community-Dwelling Elderly Population: A Cross- Sectional Study

2021 ◽  
Author(s):  
Aimee de Araujo Cabral Pelizari ◽  
Danielle Aparecida Gomes Pereira ◽  
Daniele Sirineu Pereira ◽  
Adriana Netto Parentoni ◽  
Leani Souza Máximo Pereira
Keyword(s):  
Vitamin D ◽  
Muscle Strength ◽  
Functional Capacity ◽  
Elderly Population ◽  
Hypovitaminosis D ◽  
Community Dwelling ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Vitamin D Levels

Abstract Background: Although there have been studies on the association between hypovitaminosis D status with muscle strength and functional capacity, there were few studies on Brazilian community-dwelling elderly population. Therefore, this study aims to assess the association of hypovitaminosis D with muscle strength and functional capacity in a sample Brazilian community-dwelling elderly population.Methods: An analytical, cross-sectional observational study with a convenience sample was conducted. The 25(OH)D levels were assessed using an enzyme-linked fluorescent assay and classified according to the standardization of the Brazilian Society of Clinical Pathology/Laboratory Medicine. Hand grip strength (HGS) and isometric quadriceps strength (IQS) were measured using manual Jamar® and Lafayette® 01165 dynamometers, respectively. Functional capacity was evaluated using the Short Physical Performance Battery (SPPB). Multiple linear regression models were used to assess the association of hypovitaminosis D with the HGS, IQS, and SPPB score via the Enter method. The models were adjusted for age, sex, presence of pain, level of physical activity, and use of vitamin D supplementation. Results: A total of 150 elderly individuals (age: 67.18±5.33 years) were included. According to the 25(OH)D levels, 60.7% had hypovitaminosis D (insufficient: 48%, deficient: 12.7%), and 39.3% had sufficient levels. No associations were found between hypovitaminosis D and the HGS (p=0.84), LogIQS (p=0.462), and SPPB score (p=0.617). In the regression model, the influence of the vitamin D levels on functional capacity was not significant, demonstrating no association between them.Conclusion: Hypovitaminosis D was not associated with decreased muscle strength and functional capacity in the sample Brazilian community-dwelling elderly population. Longitudinal studies with measurement of the time of use and levels of vitamin D are encouraged.

VIRTUAL ORTHOPEDIC-REHABILITATION-METABOLIC COLLABORATION FOR TREATING OSTEOPOROTIC HIP FRACTURES

2020 ◽  
Vol 26 (3) ◽  
pp. 332-339 ◽  
Author(s):  
Osnat Tell Lebanon ◽  
Doron Netzer ◽  
Eyal Yaacobi ◽  
Yitshal Berner ◽  
Devorah Spiegel ◽  
...  
Keyword(s):  
Primary Care ◽  
Vitamin D ◽  
Hip Fracture ◽  
Intervention Group ◽  
Osteoporosis Treatment ◽  
Health Maintenance ◽  
Post Surgery ◽  
Vitamin D Levels ◽  
Orthopedic Rehabilitation ◽  
Clinic Visits

Objective: To evaluate the effectiveness of a virtual, closed-loop protocol that treated hip fracture patients without formal clinic visits. Methods: In this prospective cohort study, an intervention group of 85 hip fracture patients (33.6%) with vitamin D levels ≥65 nmol/L who received recommendations for osteoporosis treatment, was compared to a nonintervention group of 168 (66.4%), with vitamin D <65 nmol/L. Treatment included vitamin D loading in orthopedic and rehabilitation departments for patients from both groups, and virtual, osteoporosis treatment recommendations by Metabolic Clinic physicians to patients from the intervention group upon achieving a vitamin D level ≥65 nmol/L. Recommendations were given without requiring clinic visits. Osteoporosis drug recommendations were relayed to primary care physicians. The primary endpoint was patients receiving osteoporosis drugs within 12-months post-surgery. Secondary endpoints were patients issued drugs within 3- and 6-months post-surgery, and 1-year post-fracture mortality rates. Results: Among 253 hip fracture patients (81.3 ± 10.7 years-of-age, 68.8% women), the postintervention osteoporosis medication issue rate was higher than in the nonintervention group (48.2% versus 22.0%, respectively; P<.001). More intervention group patients received drugs 3 months (18.8% versus 2.9%; P<.001) and 6 months after surgery (40% versus 5.9%; P<.001). One-year mortality was lower among patients who received any osteoporosis medications (either through our intervention or from community physicians) than among untreated patients (5.1% versus 26.3%; P<.001). Conclusion: Virtual orthopedic-rehabilitation-metabolic collaboration increased osteoporosis treatment rates post-hip fracture. Yet, treatment rates remained <50%. Additional research is required to increase treatment rates further, such as providing drug therapy shortly after surgery, perhaps during rehabilitation, or lowering the vita-min D threshold. Abbreviations: CHS = Clalit Health Services; FLS = Fracture liaison service; HMO = Health Maintenance Organization; MMC = Meir Medical Center; PCP = primary care physician

scholarly journals Are there any links between blood statuses of vitamin B12, B9, and D with depression in the elderly population living in nursing homes? A descriptive-analytical study from Tehran-Iran

2021 ◽  
Vol 11 (3) ◽  
pp. 152-159
Author(s):  
Lyly Nazemi ◽  
Ingvar Karlsson ◽  
Ingmar Skoog ◽  
Margda Waern ◽  
Mostafa Hosseini ◽  
...  
Keyword(s):  
Vitamin D ◽  
Nursing Homes ◽  
Vitamin B12 ◽  
Elderly Population ◽  
Dental Health ◽  
Nursing Home Residents ◽  
The Elderly ◽  
Vitamin Deficiencies ◽  
Vitamin B9 ◽  
Vitamin D Levels

Background: Nutritional deficiency has been suggested as a cause of depression in old age. The present study was performed to evaluate statuses of vitamin B12, Folate (vitamin B9), and vitamin D and their associations with depression among the elderly population living in nursing homes in Tehran-Iran. Methods: One-hundred and seventy subjects from 17 randomly selected nursing homes (NH) (Tehran-Iran) were enrolled in the study. Depression, nutritional statuses, history of chronic diseases, dental health, the levels of exposure to sunlight, the level of satisfaction associated with food quality, and NH staff were evaluated for determining possible relations between depression with vitamin B12, Folate, and vitamin D levels. Results: In the present study Folate and vitamin D deficiencies were found in 96% and 56% of subjects. No correlations were observed between depression with vitamin B12 (P=0.47), Folate (P=0.16) and Vitamin D (P=0.24) levels. Conclusion: The results delineate the high prevalence of vitamin deficiencies among elderly nursing home residents; however, no associations were observed between depression and these nutritional factors. Further studies considering other risk factors and more nutritional micronutrients are suggested.

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