scholarly journals Ultra-high b-value DWI in distinguishing fresh gray matter ischemic lesions from white matter ones: a comparative study with routine and high b-value DWI

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Xinming Huang ◽  
Xue Xu ◽  
Yifan Sun ◽  
Guoen Cai ◽  
Rifeng Jiang ◽  
...  
Keyword(s):  
White Matter ◽  
Comparative Study ◽  
Gray Matter ◽  
B Value ◽  
High B Value

High b-value diffusion-weighted imaging: A sensitive method to reveal white matter differences in schizophrenia

2012 ◽  
Vol 201 (2) ◽  
pp. 144-151 ◽  
Author(s):  
Philipp Sebastian Baumann ◽  
Leila Cammoun ◽  
Philippe Conus ◽  
Kim Quang Do ◽  
Pierre Marquet ◽  
...  
Keyword(s):  
White Matter ◽  
Diffusion Weighted Imaging ◽  
B Value ◽  
High B Value ◽  
Diffusion Weighted ◽  
Sensitive Method

Accelerated maturation of white matter in young children with autism: A high b value DWI study

NeuroImage ◽  
2007 ◽  
Vol 37 (1) ◽  
pp. 40-47 ◽  
Author(s):  
Dafna Ben Bashat ◽  
Vered Kronfeld-Duenias ◽  
Ditza A. Zachor ◽  
Perla M. Ekstein ◽  
Talma Hendler ◽  
...  
Keyword(s):  
White Matter ◽  
Young Children ◽  
Children With Autism ◽  
B Value ◽  
High B Value ◽  
Young Children With Autism

The Diagnostic Value of Multi Ultra High-b-value DWI for Alzheimer’s Disease

2021 ◽  
Author(s):  
Tianxiu Zheng ◽  
Qiuyan Chen ◽  
Yanhua Qiu ◽  
Deyong Zhang ◽  
Liwei Shi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
B Value ◽  
Diagnostic Value ◽  
White Matter Hyperintensity ◽  
Periventricular White Matter ◽  
High B Value ◽  
Left Hippocampus ◽  
Hippocampus Volume

Abstract To evaluate the diagnostic value of multi-ultra high b-value diffusion-weighted imaging (UHBV-DWI) in Alzheimer’s disease (AD), and to build a regression prediction modelfor AD.90 participants including 30 AD, 30 mild cognitive impairments (MCI) and 30 volunteers without neurological diseases were enrolled to perform with hippocampal volume, white matter hyperintensities volume (WMH volume), periventricular white matter hyperintensity (PVWMH) score, deep white matter hyperintensity (DWMH) score and UHBV-DWI.We found UHBV-DWI outperformed in the diagnosis of AD (AUC = 0.858), and multiple linear regression model: y = 0.515 + 0.018 *(WMH volume) + 0.221 *(ADCuh value)-0.359 *(left hippocampus volume) were established.So we came to a conclusion: UHBV-DWI is helpful for diagnosing AD, and the combination of WMH volume and left hippocampus volume has a better diagnostic performance.

scholarly journals Normal white matter development from infancy to adulthood: Comparing diffusion tensor and high b value diffusion weighted MR images

2005 ◽  
Vol 21 (5) ◽  
pp. 503-511 ◽  
Author(s):  
Dafna Ben Bashat ◽  
Liat Ben Sira ◽  
Moshe Graif ◽  
Pazit Pianka ◽  
Talma Hendler ◽  
...  
Keyword(s):  
White Matter ◽  
Diffusion Tensor ◽  
B Value ◽  
Mr Images ◽  
High B Value ◽  
Diffusion Weighted ◽  
White Matter Development ◽  
Normal White Matter

scholarly journals High b value DWI in evaluation of the hyperacute cerebral ischemia at 3T: A comparative study in an embolic canine stroke model

2016 ◽  
Vol 12 (2) ◽  
pp. 951-956 ◽  
Author(s):  
Qiguang Cheng ◽  
Xiaoquan Xu ◽  
Qingquan Zu ◽  
Shanshan Lu ◽  
Jing Yu ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Comparative Study ◽  
B Value ◽  
Stroke Model ◽  
High B Value

scholarly journals Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Hikaru Fukutomi ◽  
Matthew F. Glasser ◽  
Katsutoshi Murata ◽  
Thai Akasaka ◽  
Koji Fujimoto ◽  
...  
Keyword(s):  
Gray Matter ◽  
Diffusion Tensor ◽  
B Value ◽  
Tensor Model ◽  
High B Value ◽  
Cortical Gray Matter

scholarly journals Estimating intra-axonal axial diffusivity in the presence of fibre orientation dispersion

2020 ◽  
Author(s):  
Amy FD Howard ◽  
Frederik J Lange ◽  
Jeroen Mollink ◽  
Michiel Cottaar ◽  
Mark Drakesmith ◽  
...  
Keyword(s):  
White Matter ◽  
Fibre Orientation ◽  
Free Water ◽  
Orientation Distribution ◽  
B Value ◽  
Axial Diffusivity ◽  
High B Value ◽  
Axonal Compartment ◽  
Two Parameters

AbstractBy analysing the diffusion MRI signal, we can infer information about the microscopic structure of the brain. Two parameters of interest - the intra-axonal axial diffusivity and fibre orientation dispersion - are potential biomarkers for very different aspects of the white matter microstructure, yet they are difficult to disentangle. The parameters covary such that, if one is not accurately accounted for, the other will be biased. In this work we use high b-value data to isolate the signal from the intra-axonal compartment and resolve any degeneracies with the extra-axonal compartment. In the high b-value regime, we then use a model of dispersed sticks to estimate the intra-axonal axial diffusivity and fibre orientation distribution on a voxelwise basis. Our results in in vivo, human data show an intra-axonal axial diffusivity of ~ 2.3 – 3 μm2/ms, where 3 μm2/ms is the diffusivity of free water at 37°C. The intra-axonal axial diffusivity is seen to vary considerably across the white matter. For example, in the corpus callosum we find high values in the genu and splenium, and lower values in the midbody. Furthermore, the axial diffusivity and orientation dispersion appear negatively correlated, behaviour which we show is consistent with the presence of fibre undulations but not consistent with a degeneracy between fanning fibres and axial diffusivity. Finally, we demonstrate that the parameter maps output from Neurite Orientation Dispersion and Density Imaging (NODDI) change substantially when the assumed axial diffusivity was increased from 1.7 to 2.5 or 3 μm2/ms.

scholarly journals Brain Reserve in a Case of Cognitive Resilience to Severe Leukoaraiosis

2020 ◽  
pp. 1-10
Author(s):  
Dana M. Szeles ◽  
Nicholas J. Milano ◽  
Hunter J. Moss ◽  
Maria Vittoria Spampinato ◽  
Jens H. Jensen ◽  
...  
Keyword(s):  
White Matter ◽  
Diffusion Mri ◽  
Diffusion Tensor ◽  
Imaging Finding ◽  
B Value ◽  
Brain Reserve ◽  
High B Value ◽  
Positive Antibody ◽  
The Face ◽  
Magnetic Resonance Imaging Mri

Abstract Objective: Leukoaraiosis, or white matter rarefaction, is a common imaging finding in aging and is presumed to reflect vascular disease. When severe in presentation, potential congenital or acquired etiologies are investigated, prompting referral for neuropsychological evaluation in addition to neuroimaging. T2-weighted imaging is the most common magnetic resonance imaging (MRI) approach to identifying white matter disease. However, more advanced diffusion MRI techniques may provide additional insight into mechanisms that influence the abnormal T2 signal, especially when clinical presentations are discrepant with imaging findings. Method: We present a case of a 74-year-old woman with severe leukoaraoisis. She was examined by a neurologist, neuropsychologist, and rheumatologist, and completed conventional (T1, T2-FLAIR) MRI, diffusion tensor imaging (DTI), and advanced single-shell, high b-value diffusion MRI (i.e., fiber ball imaging [FBI]). Results: The patient was found to have few neurological signs, no significant cognitive impairment, a negative workup for leukoencephalopathy, and a positive antibody for Sjogren’s disease for which her degree of leukoaraiosis would be highly atypical. Tractography results indicate intact axonal architecture that was better resolved using FBI rather than DTI. Conclusions: This case illustrates exceptional cognitive resilience in the face of severe leukoaraiosis and the potential for advanced diffusion MRI to identify brain reserve.

Sign in / Sign up

Export Citation Format

Share Document