Secreted reporter proteins, a valuable complementary tool for non-invasive preclinical monitoring of brain tumour growth

2016 ◽  
Vol 5 (S7) ◽  
pp. S1486-S1488 ◽  
Author(s):  
Ludwig J. Dubois ◽  
Frank Verhaegen ◽  
Marc A. Vooijs
2021 ◽  
Vol 229 ◽  
pp. 01034
Author(s):  
Vikas Kumar

Brain tumour segmentation aims to separate the various types of tumour tissues like active cells, necrotic core, and edema from normal brain tissues of substantia alba (WM), grey matter (GM), and spinal fluid (CSF). Magnetic Resonance Imaging based brain tumour segmentation studies are attracting more and more attention in recent years thanks to non-invasive imaging and good soft tissue contrast of resonance Imaging (MRI) images. With the event of just about two decades, the ingenious approaches applying computer-aided techniques for segmenting brain tumour are getting more and more mature and coming closer to routine clinical applications. the aim of this paper is to supply a comprehensive overview for MRIbased brain tumour segmentation methods. Firstly, a quick introduction to brain tumours and imaging modalities of brain tumours is given in this proposed research, convolution based optimization. These stepwise step refine the segmentation and improve the classification parameter with the assistance of particle swarmoptimization.


Nature ◽  
2004 ◽  
Vol 428 (6980) ◽  
pp. 328-332 ◽  
Author(s):  
Igor Garkavtsev ◽  
Sergey V. Kozin ◽  
Olga Chernova ◽  
Lei Xu ◽  
Frank Winkler ◽  
...  

Author(s):  
Manimurugan S ◽  

Determining the size of the tumor is a significant obstacle in brain tumour preparation and objective assessment. Magnetic Resonance Imaging (MRI) is one of the non-invasive methods that has emanated without ionizing radiation as a front-line diagnostic method for brain tumour. Several approaches have been applied in modern years to segment MRI brain tumours automatically. These methods can be divided into two groups based on conventional learning, such as support vectormachine (SVM) and random forest, respectively hand-crafted features and classifier method. However, after deciding hand-crafted features, it uses manually separated features and is given to classifiers as input. These are the time consuming activity, and their output is heavily dependent upon the experience of the operator. This research proposes fully automated detection of brain tumor using Convolutional Neural Network (CNN) to avoid this problem. It also uses brain image of high grade gilomas from the BRATS 2015 database. The suggested research performs brain tumor segmentation using clustering of k-means and patient survival rates are increased with this proposed early diagnosis of brain tumour using CNN.


2019 ◽  
Vol 5 (2) ◽  
pp. 29 ◽  
Author(s):  
Ambre Chapuis ◽  
Elizabeth Ballou ◽  
Donna MacCallum

Traditional in vivo investigation of fungal infection and new antifungal therapies in mouse models is usually carried out using post mortem methodologies. However, biomedical imaging techniques focusing on non-invasive techniques using bioluminescent and fluorescent proteins have become valuable tools. These new techniques address ethical concerns as they allow reduction in the number of animals required to evaluate new antifungal therapies. They also allow better understanding of the growth and spread of the pathogen during infection. In this review, we concentrate on imaging technologies using different fungal reporter proteins. We discuss the advantages and limitations of these different reporters and compare the efficacy of bioluminescent and fluorescent proteins for fungal research.


Author(s):  
José Trobia ◽  
Kun Tian ◽  
Antonio M Batista ◽  
Celso Grebogi ◽  
Hai-Peng Ren ◽  
...  

2020 ◽  
Vol 22 (3) ◽  
pp. 282-288 ◽  
Author(s):  
Xinjian Li ◽  
Xu Qian ◽  
Bin Wang ◽  
Yan Xia ◽  
Yanhua Zheng ◽  
...  

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