scholarly journals In vivo and in vitro outcomes of alumina, zirconia and their composited ceramic-on-ceramic hip joints

2013 ◽  
Vol 121 (1412) ◽  
pp. 382-387 ◽  
Author(s):  
Herman Shah Abd RAHMAN ◽  
Dipankar CHOUDHURY ◽  
Noor Azuan Abu OSMAN ◽  
Hanie Nadia SHASMIN ◽  
Wan Abu Bakar Wan ABAS
Author(s):  
ATHANASIOS TRIANTAFYLLOU ◽  
GEORGIOS PAPAGIANNIS ◽  
SOPHIA STASI ◽  
PAPATHANASIOU GEORGIOS ◽  
PANAYIOTIS KOULOUVARIS ◽  
...  

Total Hip Arthroplasty (THA) is an effective treatment for severe hip arthritis, with patients reporting high rates of satisfactory results postoperatively. There are a variety of choices regarding THA implant designs. Ceramic on Ceramic and Ceramic on Highly Cross-Linked Polyethylene (XLPE) THAs are the materials of choice nowadays. The purpose of this study is to review the effect of kinematics and kinetics on wear (in vivo and in vitro testing) that affect wear in Ceramic on Ceramic and Ceramic on XLPE total hip arthroplasties and identify possible advantages amongst them. The study hypothesis was that THA kinematics and/or kinetics, since they directly affect THA wear, could provide data for possible advantages between the examined implant designs. A systematic review of the literature identified no significant evidence for biomechanical advantages between these two prostheses in terms of wear. Further research is proposed with the use of gait analysis systems combined with surface electromyography to further investigate THA biomechanics at a laboratory set up. Wearable sensors technology could also identify detailed biomechanical parameters in more complex daily activities.


Author(s):  
D Jalali- Vahid ◽  
Z. M. Jin ◽  
D Dowson

A full numerical analysis of elastohydrodynamic lubrication (EHL) of circular point contacts was carried out in the present study under isoviscous conditions with particular reference to metal-on-metal artificial hip joints, using a modified Newton-Raphson method. It was found to be possible to incorporate directly the physiological conditions, representative of typical metal-on-metal hip implants under in-vivo walking or in-vitro simulator testing, in the present numerical solutions. The predicted minimum and central film thicknesses were compared favourably with those estimated from various formulae available in the literature. In particular, it was shown that both the minimum and the central film thickness expressions derived by Hamrock and Dowson were reasonably accurate for all the conditions considered in the present study.


2016 ◽  
Vol 100 ◽  
pp. 410-419 ◽  
Author(s):  
Armelle Perrichon ◽  
Bruno Reynard ◽  
Laurent Gremillard ◽  
Jérôme Chevalier ◽  
Frédéric Farizon ◽  
...  

2017 ◽  
Vol 71 ◽  
pp. 446-451 ◽  
Author(s):  
Giuseppe Pezzotti ◽  
Wenliang Zhu ◽  
Matteo Zanocco ◽  
Elia Marin ◽  
Nobuhiko Sugano ◽  
...  

Author(s):  
E. J. Kollar

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.


Author(s):  
M.J. Murphy ◽  
R.R. Price ◽  
J.C. Sloman

The in vitro human tumor cloning assay originally described by Salmon and Hamburger has been applied recently to the investigation of differential anti-tumor drug sensitivities over a broad range of human neoplasms. A major problem in the acceptance of this technique has been the question of the relationship between the cultured cells and the original patient tumor, i.e., whether the colonies that develop derive from the neoplasm or from some other cell type within the initial cell population. A study of the ultrastructural morphology of the cultured cells vs. patient tumor has therefore been undertaken to resolve this question. Direct correlation was assured by division of a common tumor mass at surgical resection, one biopsy being fixed for TEM studies, the second being rapidly transported to the laboratory for culture.


Author(s):  
Raul I. Garcia ◽  
Evelyn A. Flynn ◽  
George Szabo

Skin pigmentation in mammals involves the interaction of epidermal melanocytes and keratinocytes in the structural and functional unit known as the Epidermal Melanin Unit. Melanocytes(M) synthesize melanin within specialized membrane-bound organelles, the melanosome or pigment granule. These are subsequently transferred by way of M dendrites to keratinocytes(K) by a mechanism still to be clearly defined. Three different, though not necessarily mutually exclusive, mechanisms of melanosome transfer have been proposed: cytophagocytosis by K of M dendrite tips containing melanosomes, direct injection of melanosomes into the K cytoplasm through a cell-to-cell pore or communicating channel formed by localized fusion of M and K cell membranes, release of melanosomes into the extracellular space(ECS) by exocytosis followed by K uptake using conventional phagocytosis. Variability in methods of transfer has been noted both in vivo and in vitro and there is evidence in support of each transfer mechanism. We Have previously studied M-K interactions in vitro using time-lapse cinemicrography and in vivo at the ultrastructural level using lanthanum tracer and freeze-fracture.


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