scholarly journals Treatment outcome of tuberculosis patients and factors determining treatment outcome at peripheral health settings of Northern Ethiopia: a five year retrospective study

2019 ◽  
Author(s):  
Mahmud Abdulkadir ◽  
Ischa van Aken ◽  
Selam Sahle Niguse ◽  
Haftamu Hailekiros ◽  
Mark Spigt
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Treatment Failure ◽  
Treatment Success ◽  
Northern Ethiopia ◽  
Tuberculosis Patients ◽  
Retreatment Case ◽  
National Tuberculosis ◽  
The Mean ◽  
Extra Pulmonary

Abstract Objective Evidences of treatment outcome and identifying factors associated with treatment failure through a register based retrospective study have significant contribution in in the improvement of a National Tuberculosis Program. However there is a scarcity of data from peripheral health settings in Ethiopia. Therefore this study is aimed at determining treatment outcome of tuberculosis patients and associated factors. Results A total of 3471 patient records were included. More than half, (58%) were males and the mean age was 34 ± 17 years. Majority (43%) had extra-pulmonary TB. From the total TB patients, 18.8% were HIV co infected. The overall treatment success was 89.5%. Being HIV coinfected, pulmonary negative, extra-pulmonary and retreatment case were significantly associated with treatment failure.

scholarly journals Treatment outcome of tuberculosis patients at Adare general Hospital, Hawassa, Southern Ethiopia. (A five year retrospective study)

2019 ◽  
Author(s):  
Bezunesh Tsegaye ◽  
Zufan Bedewi ◽  
Solomon Lemma Asnake
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Treatment Outcomes ◽  
General Hospital ◽  
Treatment Success ◽  
Southern Ethiopia ◽  
P Value ◽  
Tuberculosis Patients ◽  
Tb Treatment ◽  
Extra Pulmonary

Abstract Background Globally still Tuberculosis remains a major public health problems and socio-economic issue in the 21st century. Ethiopia is among the countries most heavily affected by Tuberculosis, where it is the leading cause of morbidity, the third cause of hospital admission and the second cause of death. To improve Tuberculosis management and control, early detection of cases, effective treatment and persistent evaluation of treatment outcome are vital issues that should be taken into consideration. Hence, this study was designed to determine treatment outcomes and associated risk factors among TB patients registered and receiving anti-TB treatment at Adare general Hospital, Southern Ethiopia. Methods A five years retrospective study was conducted by reviewing medical records of TB patients at Adare general Hospital. A total of 1151 Tuberculosis patients’ cards registered from (September 2013 to August 2017) for treatment at TB clinic were reviewed. Data was coded, cleaned and entered into Microsoft Excel sheet then ported and analyzed using SPSS version 20 statistical soft ware. Logistic regression with odds ratios (OR) along with the 95% confidence interval was computed and interpreted. A P value <0.05 was declared as statistically significant. Result Among 1122 cases 620 (55.3%) were male, 748(66.7%) were from urban areas, 319 (28.4%) were smear positive, 352 (31.4%) were smear negative and 451 (40.2%) were extra pulmonary patients. Of the 1122 284 (25.3%) were cured, 753(67.1%) completed treatment, 29(2.6%) defaulted, 53(4.7%) died and 3 (0.3%) had treatment failure. The mean treatment success rate was 92.4%. The risk of unsuccessful TB treatment outcome was significantly higher among TB patients from rural areas (AOR = 0.43, 95% CI: 0.27, 0.67); patients with extra pulmonary TB (AOR = 0.87, 95% CI; 0.67, 1.14), and HIV positive TB patients (AOR = 5.47, 95% CI; 3.47, 8.63) were more likely to have poor treatment outcomes as compared to their counter parts. Conclusion The treatment success rates of Tuberculosis, at Adare hospital was comparable to national health facility level coverage, but it should be maintained and strengthen further to attain tuberculosis related national and millennium goal.

scholarly journals A 5-year experience characterizing the demographic and clinical profile and directly observed treatment short-course treatment outcome in National Tuberculosis Center of Duhok province, Iraqi Kurdistan

2020 ◽  
Vol 8 ◽  
pp. 205031212092105
Author(s):  
Muayad Aghali Merza
Keyword(s):  
Treatment Outcome ◽  
Pulmonary Tuberculosis ◽  
Treatment Outcomes ◽  
Clinical Profile ◽  
Patient Treatment ◽  
Extra Pulmonary Tuberculosis ◽  
Tuberculosis Patients ◽  
National Tuberculosis Program ◽  
National Tuberculosis ◽  
Extra Pulmonary

Background: The objectives were to describe the demographic and clinical profile and treatment outcomes in the National Tuberculosis Program Center of Duhok governorate. Methods: This was a descriptive retrospective study of all forms of drug-susceptible tuberculosis cases in the National Tuberculosis Program Center of Duhok. The Electronic Nominal Recording Reporting System data of tuberculosis cases were reviewed during 2014–2018. Information on the demographic, clinical, and laboratory characteristics of the patients were analyzed. Tuberculosis trends and treatment outcomes were determined. Results: A total of 1063 tuberculosis patients visited the National Tuberculosis Program Center, of whom 905 were from Duhok. The estimated tuberculosis notification rate per 100,000 people in Duhok governorate was 14.06, 16.16, 10.43, 11.05, and 10.34 for the years 2014, 2015, 2016, 2017, and 2018, respectively. The most affected age group was 15–24 years. The male cases were predominant. Most patients (97.3%) were native Iraqi. There were 718 (67.5%) pulmonary tuberculosis cases and 345 (32.5%) extra-pulmonary tuberculosis cases; tuberculosis lymphadenitis was the most common presentation. The majority of extra-pulmonary tuberculosis patients were females aged 15–24 years (p = 0.019), and patients aged ⩾65 years were associated with pulmonary tuberculosis and extra-pulmonary tuberculosis in males (p ⩽ 0.001). The highest tuberculosis incidence occurred in winter (288 patients). The patient treatment outcomes were as follows: 90.7% successful treatment, 1.6% lost to follow-up, 6.7% death, 0.3 transferred out, and 0.8 treatment failure. Conclusion: There was a high frequency of extra-pulmonary tuberculosis, which may reflect overestimation in its diagnosis. Therefore, meticulous evaluations should be provided. The treatment outcome was satisfactory in the center. Hence, we should maintain the favorable work to attain tuberculosis control objectives. Performing GeneXpert for all tuberculosis cases and introducing culture and drug susceptibility testing should be an urgent plan to strengthen the diagnosis of susceptible and drug-resistant tuberculosis cases.

scholarly journals Treatment outcome of tuberculosis patients at Adare general Hospital,Hawassa, Southern Ethiopia (A five year retrospective study)

2019 ◽  
Author(s):  
Bezunesh Tsegaye ◽  
Zufan Bedewi ◽  
Solomon Asnake
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Success Rate ◽  
General Hospital ◽  
Urban Areas ◽  
Treatment Success ◽  
Treatment Success Rate ◽  
Southern Ethiopia ◽  
Tb Treatment ◽  
Extra Pulmonary

Abstract Objective This institution based retrospective study was conducted to determine the treatment outcome of TB patients and investigate and associated risk factors among TB patients registered at Adare general Hospital, Southern Ethiopia. Result Among 1122 cases 620 (55.3%) were male, 748(66.7%) were from urban areas, 319 (28.4%) were smear positive, 352 (31.4%) were smear negative and 451 (40.2%) were extra pulmonary patients. Of the 1122 284 (25.3%) were cured, 753(67.1%) completed treatment, 29(2.6%) defaulted, 53(4.7%) died and 3 (0.3%) had treatment failure. The overall mean treatment success rate was 92.4%. The risk of unsuccessful TB treatment outcome was significantly higher among TB patients from rural areas (AOR = 0.435, 95% CI: 0.279, 0.679); patients with extra pulmonary TB (AOR = 0.877, 95% CI; 0.671, 1.146), and HIV positive TB patients (AOR = 5.478, 95% CI; 3.474, 8.639) were more likely to have poor treatment outcomes as compared to their counter parts. Key words: TB treatment outcome, Tuberculosis, DOTS, Treatment success rate.

scholarly journals Factors Associated with Unsuccessful Treatment of Tuberculosis in Arsi-Robe Hospital, Arsi Zone, Ethiopia: A Retrospective Study

2021 ◽  
Author(s):  
Addisu Assefa ◽  
Ararsa Girma ◽  
Helmut Kloos
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Rural Areas ◽  
Urban Areas ◽  
Treatment Success ◽  
Hiv Positive ◽  
Multivariable Logistic Regression Analysis ◽  
Eastern Ethiopia ◽  
Factors Associated ◽  
Unsuccessful Treatment

Abstract Background: Tuberculosis remains a major global health problem and ranks along with the human immunodeficiency virus (HIV) as a leading cause of mortality worldwide. The aim of this study was to investigate the treatment outcome of tuberculosis, and factors associated with treatment outcome of tuberculosis in TB patients enrolled in Arsi-Robe Hospital, Oromia regional state, South eastern Ethiopia between January 2013 to December 2017. Methods: An Institutional-based retrospective study was conducted in Arsi-Robe Hospital from 2013 to 2017 in study patients who had all forms of TB in DOTS clinic. The predictors of treatment outcomes were analyzed through bivariate and multivariable logistic regression analysis and a P-value < 0.05 were considered statistically significant. Results: Out of the 257 registered TB patients, most of them were males (57.9%), from rural areas (62.6%) and in age of 15-24 category (39.3%). PTB-, PTB+ and EPTB were recorded in 48.2%, 32% and 19.8% of the patients, respectively. Among all cases, 8.6% had TB-HIV co-infection. Among all TB cases, 84.0% had successful treatment outcome. TB patients from urban areas (AOR: 3.34, 95% CI: 1.33­8.38, P = 0.01), with failure treatment (AOR: 6.66, 95% CI = 1.12- 39.57; P = 0.037) and HIV positive (AOR: 4.92, 95% CI = 1.38-17.51; P = 0.014) had higher odd of unsuccessful treatment outcome of tuberculosis. However, TB patients with PTB+ (AOR: 0.1470, 95% CI = 0.031-0.687; P = 0.015) and EPTB (AOR: 0.194, 95% CI = 0.054-0.688; P = 0.011) had significantly lesser odd of unsuccessful treatment outcome. Conclusions: Being urban resident, treatment failure and HIV positive considerably challenge the treatment outcome of tuberculosis, but being PTB+ and EPTB were associated with higher treatment success rate of TB. Continuous follow-up of patients with unsuccessful treatment outcome of tuberculosis with strengthened implementation of the DOTs strategies are suggested. Trial Registered: retrospectively registered

scholarly journals Association of type of tuberculosis with treatment outcome among paediatric tuberculosis patients in Bhopal city

2017 ◽  
Vol 4 (11) ◽  
pp. 4205
Author(s):  
Sheloj Joshi
Keyword(s):  
Treatment Outcome ◽  
Age Groups ◽  
Study Data ◽  
Age Group ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Paediatric Patients ◽  
Immunodeficiency Virus ◽  
Extra Pulmonary ◽  
Paediatric Tuberculosis

Background: Tuberculosis causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the human immunodeficiency virus (HIV).The younger the child, the more are the chances of complications and death from the disease. The objective of the study was to find out the association of type of tuberculosis with the treatment outcome of paediatric TB patients registered under RNTCP in Bhopal city.Methods: A longitudinal study was conducted in all tuberculosis treatment units (TU) of Bhopal city. All paediatric patients in the age group of 0 to 14 years diagnosed as TB and registered under RNTCP and fulfilling inclusion criteria during January 2013 to June 2013 were included in the study. Data regarding paediatric TB patients was collected by using a structured questionnaire. Information was also obtained in two subsequent visits of the patient, one at the end of intensive phase to know the response of treatment and other at the end of the treatment for treatment outcome. The data was analysed on statistical software SPSS vs.20.Results: The present study was conducted on 165 paediatric Tuberculosis patients who were registered for DOTS treatment under RNTCP. Pulmonary TB is common in all the age group of <1 and 1-10 years. Out of 165 paediatric patients,93.33% of patients were treatment completed in which 54.54% were pulmonary cases and 45.45% were extra pulmonary while 4.84% were declared cured, thus showing statistically significant association (X2=9.758 and p=0.04, df=4) between type of Tuberculosis and treatment outcome.Conclusions: Pulmonary TB is common in the age groups of <1 and 1-10 years while in 11-14 years of age group extra pulmonary TB is more common. There is statistically significant association between type of Tuberculosis and treatment outcome. 

scholarly journals Implementasi Penanggulangan Tuberkulosis di Puskesmas Glugur Darat Kota Medan

2019 ◽  
Vol 1 (2) ◽  
pp. 196-205
Author(s):  
Muchti Yuda Pratama ◽  
Fitriani Pramita Gurning ◽  
Suharto Suharto
Keyword(s):  
Health Promotion ◽  
Treatment Success ◽  
Community Health Center ◽  
Control Policy ◽  
Qualitative Approach ◽  
Tuberculosis Control ◽  
Cure Rate ◽  
Tuberculosis Patients ◽  
Qualitative Approaches ◽  
National Tuberculosis

This study aims to determine the implementation of tuberculosis control policies at Puskesmas Glugur Darat. This research design uses quantitative and qualitative approaches, where the method is a qualitative approach. The results showed that the implementation of the tuberculosis control policy at the Glugur Darat Community Health Center had not run as well as possible. The cure rate for tuberculosis patients at Puskesmas Glugur Darat was 46.15% and less than the national target of> 85% and the treatment success rate of 65.38% was also less than the national target of 85%. In conclusion, the head of the puskesmas, tuberculosis officers, and cadres have used the national tuberculosis guidelines and the DOTS strategy well, but implementation has not gone well because there are still people who do not participate in health promotion activities.   Keywords: Land Glug, Implementation, Countermeasures for Tuberculosis Policy

scholarly journals Impact of HIV Status on Treatment Outcome of Tuberculosis Patients Registered at Arsi Negele Health Center, Southern Ethiopia: A Six Year Retrospective Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153239 ◽  
Author(s):  
Gebreslassie Gebremariam ◽  
Getachew Asmamaw ◽  
Muktar Hussen ◽  
Mengistu Z. Hailemariam ◽  
Demissie Asegu ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Health Center ◽  
Southern Ethiopia ◽  
Hiv Status ◽  
Tuberculosis Patients
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