Epidemiology of Chronic Kidney Diseases in Ethiopian Police Hospital: Institutional based cross sectional study

2019 ◽  
Author(s):  
Muna Abdulkadr ◽  
Hailu Merga ◽  
Biru Abdissa ◽  
Lamessa Dube
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Diabetes mellitus remains the leading cause of end stage renal disease in most countries in the world. In Ethiopia, renal complications of diabetes may remain unrecognized due to limited diagnostic resources. As a result, the studies that shows the prevalence of chronic kidney disease (CKD) and its risk factors among adult diabetics in Ethiopia are flimsy. Hence, this study was aimed at assessing the prevalence of chronic kidney disease and associated factors among diabetic patients who attended federal police hospital diabetic clinic in Addis Ababa. Methods Hospital based cross sectional study was conducted among 362 Diabetes Mellitus patients using systematic sampling method. Chronic kidney disease stage was categorized according to the classification system established by the National Kidney Foundation Kidney Disease out comes Quality Initiative and defined by Estimated Glomerular Filtration Rate (eGFR) <60ml/min/1.73m2. Analysis was performed using SPSS. The prevalence estimates for the reduced GFR and overall chronic kidney disease were obtained. Binary logistic regression was used to see associated factors with chronic kidney disease. Results The prevalence of chronic kidney disease diagnosed by Cockroft-Gault equation and Modification of Diet in Renal Disease equation was 14.6% and 7.7% respectively. Age 50-59 years (AOR= 4.0; 95% CI:1.2, 13) by Cockroft-Gault equation (CG), age 60-69 years (AOR=5.8 95%CI:1.5,21.0) by Modification of Diet in Renal Disease (MDRD) and (AOR;22.9 95%CI:7.1,74.2) by CG, age 70 years and above (AOR=4.7; 95 CI: 1.1, 19.7) by MDRD and (AOR= 22.9; 95%CI:7.1,74.2) by CG, BMI (AOR=2.2; 95% CI:1.6, 4.2) by CG, and previous kidney disease (AOR=6.2 95%CI:2.0,8.4) by MDRD and (AOR;4.6 95%CI:1.9,10.8) C-G equation were found to have a significant association with chronic kidney disease after an adjustment done using multivariate analysis. Conclusion The prevalence of chronic kidney disease among Diabetic patients in this study was high. Age, BMI and previous recurrent kidney disease were associated with Chronic Kidney Disease. Preventive measures like giving health education and screening of patients with risk factors should get more attention.

scholarly journals Knowledge regarding the prevention of chronic kidney disease in hypertensive and diabetic patients: a cross-sectional study

2017 ◽  
Vol 30 (suppl 1) ◽  
pp. 55-62
Author(s):  
Elaine Cristina Santa Cruz de Moura ◽  
Jefferson Belarmino Nunes Barbosa ◽  
Patrícia Érika de Melo Marinho
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Physical Exercise ◽  
Structural Changes ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

Abstract Introduction: Hypertension (HT) and diabetes mellitus (DM) lead to functional and structural changes in target organs such as the kidneys, characterizing the need for preventive actions to avoid Chronic Kidney Disease (CKD). Objective: To verify cardiologists’ and endocrinologists’ knowledge, indications and practices regarding prevention of CKD in patients with HT and DM. Methods: A cross-sectional study with 14 cardiologists and 5 endocrinologists applying a questionnaire about the conduct of these professionals regarding the prevention of CKD in hypertensive and diabetic patients. Results: One hundred percent of the cardiologists and endocrinologists did not request specific tests for CKD screening (albuminuria and glomerular filtration rate (GFR), although 92.9% of the cardiologists and 60.0% of the endocrinologists report referring hypertensive and diabetic patients with impaired renal function to nephrologists. One hundred percent of the interviewees recognize the importance of physical exercise for their patients; however, only 68.6% of cardiologists and 60% of endocrinologists indicated a physiotherapist and/or physical trainer to implement these exercises. Conclusion: The professionals evaluated in this study do not request microalbuminuria and GFR examinations for hypertensive and diabetic patients as a follow-up routine, despite having found cases of renal function impairment in these patients; in contrast to what is proposed in the guidelines for hypertension and diabetes mellitus. They recognize the importance of physical exercise and report indicating their patients to a physiotherapist and/or physical trainer. We suggest continuing the study in order to ascertain the reasons for their not complying with the respective guidelines.

scholarly journals Prevalence of Anemia and Its Associated Factors among Chronic Kidney Disease patients at University of Gondar Hospital, North West Ethiopia: a Hospital-based Cross Sectional Study

2019 ◽  
Author(s):  
Hailemariam Adera ◽  
Workagegnehu Hailu ◽  
Ayineshet Adane ◽  
abilo tadesse
Keyword(s):  
Chronic Kidney Disease ◽  
Logistic Regression ◽  
Kidney Disease ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Rural Residence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prevalence Of Anemia

Abstract Background chronic kidney disease (CKD) is a global public health problem associated with progressive decline in kidney function and adverse cardiovascular outcome. Anemia in CKD has substantial adverse outcomes in CKD patients. There is paucity of published data on prevalence of anemia and its associated factors among CKD patients in Northwest Ethiopia. Objective This study aimed to determine the prevalence of anemia and its associated factors among CKD patients at University of Gondar hospital, Northwest Ethiopia. Methods A hospital-based cross-sectional study was conducted from May1, to September 30, 2018. Consecutive sampling was used to recruit 251 study subjects. Data regarding patient’s socio-demographics, clinical characteristics and laboratory parameters were collected from patients’ interview and medical records. Data was analyzed using SPSS version 20. Bi-variate and multi-variate logistic regression analyses were used to identify predictors of anemia in CKD patients. P<0.05 was used to declare association. Results The prevalence of anemia was high (64.5%), and tended to increase as eGFR declined. Hypertension (45%), chronic glomerulonephritis (24%) and diabetes (20%) were common causes of CKD. Multivariate logistic regression analysis revealed rural residence (AOR= 2.75, 95% CI: 1.34-5.65, p=0.006), BMI<18.5 kg/m2 (AOR=6.78, 95% CI: 1.32-34.73, p=0.022) and BMI of 18.5-24.9 kg/m2 (AOR=5.04, 95% CI: 1.26-20.10, p=0.022), and having hemodialysis history (AOR=3.59, 95% CI: 1.24-10.38, p=0.018) were predictors of anemia in CKD patients. Conclusion Prevalence of anemia in CKD patients was high (64.5%). Rural residence, non-obese body habitus and having hemodialysis history were found to be predictors of anemia in CKD patients. Periodic screening and intervention for anemia in CKD patients should be practiced to prevent its sequelae.

scholarly journals Association of Retinopathy with Chronic Kidney Disease in Diabetes Mellitus

2018 ◽  
Vol 8 (3) ◽  
pp. 210-214
Author(s):  
Rushda Sharmin Binte Rouf ◽  
SM Ashrafuzzaman ◽  
Zafar Ahmed Latif
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Diabetic Retinopathy ◽  
Kidney Disease ◽  
Strong Association ◽  
Albumin Excretion Rate ◽  
Cross Sectional Study ◽  
Fundus Photography ◽  
Diabetic Patients ◽  
Cross Sectional

Background: Diabetic retinopathy (DR) and nephropathy are two major complications of diabetes mellitus carrying significant morbidity and mortality. In this study DR was investigated in different stages of chronic kidney disease (CKD) to find out possible association of these two devastating complications.Methods: This cross-sectional study was conducted in 150 diabetic patients having CKD in BIRDEM. CKD was defined as estimated glomerular filtration rate (eGFR) of <60ml/min/1.73m2and/or urinary albumin excretion rate (UAER) >30 mg/day in at least two occasions in 3 months apart. Retinopathy was assessed by direct fundoscopic examination and confirmed by color fundus photography. Severe DR (SDR) included proliferative diabetic retinopathy, severe non-proliferative DR and maculopathy; whereas microaneurysm regarded as non-severe retinopathy.Results: Majority (68%) of the respondents had some form of retinopathy (38.35% SDR and 29.65% nonsevere). There was strong association between different levels of albuminuria (UAER) and DR (p<0.0001). On the contrary DR did not correspond with stages of CKD (P=0.349). Hypertension (79.5%) and dyslipidaemia (59%) were common co-morbidities.Conclusion: This study concluded that DR prevalence was more in nephropathy along with significant association with UAER. Whereas different stages of CKD was not associated with stages of DR . This finding focused the necessity of regular retinal examination irrespective of the stage of renal involvement.Birdem Med J 2018; 8(3): 210-214

scholarly journals Prevalence and predictors of chronic kidney disease among Ghanaian patients with hypertension and diabetes mellitus: A multicenter cross-sectional study

2019 ◽  
Vol 21 (10) ◽  
pp. 1542-1550 ◽  
Author(s):  
Elliot K. Tannor ◽  
Fred Stephen Sarfo ◽  
Linda M. Mobula ◽  
Osei Sarfo-Kantanka ◽  
Rexford Adu-Gyamfi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Anaemia among primary care patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD): a multicentred cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. e025125 ◽  
Author(s):  
Iliza Idris ◽  
Hizlinda Tohid ◽  
Noor Azimah Muhammad ◽  
Mohd Radzniwan A Rashid ◽  
Azainorsuzila Mohd Ahad ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Primary Care ◽  
Chronic Kidney Disease ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ckd Stage

ObjectivesThis study aimed to determine the prevalence of anaemia among patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) at primary care settings and its associated factors.Design, setting and participantsThis cross-sectional study involved 808 adult patients with T2DM and CKD who were recruited via systematic sampling from 20 public primary care clinics in Peninsular Malaysia. Their sociodemographic, clinical and biomedical profiles were collected through interviews, examination of medical records and blood testing.ResultsThe prevalence of anaemia was 31.7% (256/808). The anaemia was mainly mild (61.5%) and normocytic normochromic (58.7%). About 88.7% of the patients with anaemia were not known to have anaemia prior to the study. Among 36 patients with documented history of anaemia, 80.6% were still anaemic, and only a half received iron therapy. Multivariate regression analysis showed that women (adjusted odd ratio (AOR): 1.57, 95% CI: 1.12 to 2.21, p=0.009) and those with older age (AOR: 1.04, 95% CI: 1.01 to 1.06, p<0.001), CKD stage 3a (AOR: 2.47; 95% CI: 1.25 to 4.87, p=0.009), CKD stage 3b (AOR: 4.36; 95% CI: 2.14 to 8.85, p<0.001), CKD stage 4 (AOR: 10.12; 95% CI: 4.36 to 23.47, p<0.001), CKD stage 5 (AOR: 10.80; 95% CI: 3.32 to 35.11, p<0.001) and foot complication (AOR 3.12, 95% CI: 1.51 to 6.46, p=0.002) were more likely to have anaemia. Having higher body mass index (AOR 0.95, 95% CI: 0.92 to 0.99, p=0.012) and higher diastolic blood pressure (AOR 0.97, 95% CI: 0.95 to 0.99, p<0.001) were associated with lower odds to have anaemia.ConclusionAnaemia among patients with T2DM and CKD in primary care was common, and the majority was unrecognised. Inadequate treatment of anaemia was also prevalent. Therefore, screening of anaemia should be incorporated into the routine assessment of diabetic complications particularly for those with significant associated factors. It is hoped that such strategy could lead to early treatment and hence improve their overall care.Trial registration numberNMRR-15-660-24324.

scholarly journals Prevalence of chronic kidney disease and its associated factors in Malaysia; findings from a nationwide population-based cross-sectional study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Thamil Arasu Saminathan ◽  
Lai Seong Hooi ◽  
Muhammad Fadhli Mohd Yusoff ◽  
Loke Meng Ong ◽  
Sunita Bavanandan ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Associated Factors ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Glucose Lowering Therapeutic Strategies for Type 2 Diabetic Patients with Chronic Kidney Disease in Primary Care Setting in France: A Cross-Sectional Study

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
N. Grandfils ◽  
B. Detournay ◽  
C. Attali ◽  
D. Joly ◽  
D. Simon ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
Therapeutic Strategies ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Glucose Lowering ◽  
Patient Profile

Aim. To understand glucose lowering therapeutic strategies of French general practitioners (GPs) in the management of type 2 diabetes mellitus (T2DM) patients with chronic kidney disease (CKD).Methods. A multicenter cross-sectional study was conducted from March to June 2011 among a sample of French GPs who contribute to the IMS Lifelink Disease Analyzer database. Eligible patients were those with T2DM and moderate-to-severe CKD who visited their GPs at least once during the study period. Data were collected through electronic medical records and an additional questionnaire.Results. 116 GPs included 297 patients: 86 with stage 3a (Group 1, GFR = 45–60 mL/min/1.73 m2) and 211 with stages 3b, 4, or 5 (Group 2, GFR < 45 mL/min/1.73 m2). Patients’ mean age was approximately 75 years. Insulin was used in 19% of patients, and was predominant in those with severe CKD. More than two-thirds of patients were treated with glucose lowering agents which were either contraindicated or not recommended for CKD. Conclusion Physicians most commonly considered the severity of diabetes and not CKD in their therapeutic decision making, exposing patients to potential iatrogenic risks. The recent patient oriented approach and individualization of glycemic objectives according to patient profile rather than standard HbA1c would improve this situation.

scholarly journals Rate of glycemic control and associated factors among type two diabetes mellitus patients in Ethiopia: A cross sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251506
Author(s):  
Shambel Nigussie ◽  
Nigussie Birhan ◽  
Firehiwot Amare ◽  
Getnet Mengistu ◽  
Fuad Adem ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

Objective To assess the rate of glycemic control and associated factors among type 2 diabetes mellitus patients at Dilchora Referral Hospital, Dire Dawa, Eastern Ethiopia. Methods A cross-sectional study was conducted from 13 May to 16 August 2019. Type 2 diabetic patients on follow up at Dilchora Referral Hospital who fulfilled the inclusion criteria of the study were included. Systematic random sampling was used to select study participants. Data was collected by a face-to-face interview and review of medical records. The primary outcome was the level of blood glucose during three consecutive visits. Poor glycemic control was defined as a blood sugar level of more than 154 mg/dL based on the average of measurements from three consecutive visits. Multivariate logistic regression analysis was used to identify determinants of glycemic control. Result A total of 394 participants responded to the interview and were included in the final analysis. The overall prevalence of poor glycemic control was 45.2% (95%CI: 40.6%-50.0%). Patients who were on oral anti-diabetic drug plus insulin had more than two times greater chance of poor glycemic control than patients on oral anti-diabetic drug alone: 2.177(95%CI:1.10–4.29). The odds of poor glycemic control in patients who did not understand the pharmacist’s instructions was two times higher than patients with good understanding of instructions 1.86(95%CI: 1.10–3.13). Patients who had poor level of practice were found to have poor glycemic control: 1.69(95% CI: 1.13–2.55). Conclusion The overall prevalence of poor glycemic control was high among type 2 diabetes patients. Oral anti-diabetic drugs in combination with insulin, lack of understanding of pharmacist’s advice, and poor practice of diabetic patients were significant factors of poor glycemic control. Pharmacists should reassure the understanding of patients before discharge during counseling. Optimization of the dose of antidiabetic medications and combination of oral hypoglycemic agents should be considered.

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