scholarly journals Potential teratogenecity risk and prescription drug use among pregnant women attending maternal and child health clinic of Kemisse General Hospital, Northeastern, Ethiopia

2019 ◽  
Author(s):  
Belete Kassa Alemu ◽  
Nesredin Nigatu Wolle

Abstract Background Drug use during pregnancy requires special consideration because both fetus and the mother are affected. Drug teratogenicity is most likely to occur when drugs are taken during first trimester of pregnancy when fetal organs are formed. In addition, drugs at second and third trimester may affect the growth and functional development of the fetus or have toxic effect on fetal tissues. Objective The objective of this study was to assess potential teratogenecity risk and drug use pattern in Kemisse General Hospital. Methods An institution based cross sectional study was conducted by reviewing a one year medical records (from January 1, 2010 to December 31, 2011) of pregnant women attending maternal and child health clinic of the hospital. Systematic random sampling was employed to select a total of 263 pregnant women. Structured data abstraction format was used for collection of data and then data were coded, entered and analyzed by using Statistical Package for Social Sciences version 23. Result A total of 263 medical records of pregnant women were reviewed, of which 234 pregnant women were prescribed with a total of 430 prescription drugs. The average numbers of drugs per pregnant women was found to be 1.84. Most pregnant women 166 (63.2%) were in the third trimester and more than half of them (51.3%) were multigravida. The maximum number of drugs were prescribed in the second trimester 162 (37.67%) followed by third trimester 143(33.26%). Supplemental drugs were the most widely used medications 297 (69.07%) and followed by 82 (19.1%) drugs from category B; 54 (12.6%) drugs from category C; and the rest 7 (1.6%) drugs from category D. There was no any drug from category X. Conclusion Approximately one third of the pregnant women encountered with drugs from category B, C and D. However, there were no FDA category C and D drugs prescribed in first trimester. There was no drug utilized by pregnant women from FDA pregnancy risk category X.

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Belete Kassa Alemu ◽  
Nesredin Nigatu Wolle

Abstract Objective To investigate medications prescribed for pregnant women and their potential teratogenicity risk in Kemisse General Hospital. Result A total of 263 medical records of pregnant women were reviewed, of which 234 pregnant women were prescribed with a total of 430 prescription drugs. The average numbers of drugs per pregnant women was found to be 1.84. Most pregnant women 166 (63.2%) were in the third trimester and more than half of them (51.3%) were multigravida. The maximum number of drugs were prescribed in the second trimester 162 (37.67%) followed by third trimester 143 (33.26%). Supplemental drugs were the most widely used medications 297 (69.07%) and followed by 82 (19.1%) drugs from category B; 54 (12.6%) drugs from category C; and the rest 7 (1.6%) drugs from category D. There was no any drug from category X. Moreover, approximately one third of the pregnant women encountered with drugs from category B, C and D. However, there were no FDA category C and D drugs prescribed in first trimester.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Esther Cheptanui Muathe ◽  
Mary Kamau ◽  
Eve Rajula

Background. Globally, immunization is among the major contributors to public health, preventing 20% of childhood mortality annually. The highest fatality rates from vaccine preventable diseases are usually among children under five. Despite immunization guidelines put in place by the World Health Organization, globally, 1.5 million children die annually related to inadequate vaccination coverage. Existing literature indicate that there is an increase in nonadherence to immunization schedule in developing countries, and therefore, there is an increased demand to improve adherence to immunization schedule. Objective. To explore strategies that will improve adherence to immunization schedule among children under 24 months attending the Maternal and Child Health clinic at Kenyatta National Hospital. Methods. A cross-sectional mixed method study involving caregivers (n=214) of well babies attending the Maternal and Child Health clinic. Data was collected using semistructured questionnaires, focus group discussions, and key informant interviews and analyzed using SPSS V.20. Results. There was a significant relationship between the level of education and marital status of the caregivers and adherence to immunization schedule. Barriers found that is related to adherence to immunization schedule included far distance from health facility, baby’s sickness, and vaccine stock-outs while employment of a caregiver was a constrainer factor. Conclusion. The enabling factors to current strategies of improving adherence to immunization schedule were having more health facilities near residential areas, using text messages reminders a day before the clinic date to remind caregivers of the due date for the clinic, and constant availability of vaccines. The health system strategies that would improve adherence to immunization schedules were more flexible clinic hours, availability of vaccines on daily basis, phone call reminders by health care providers, and increasing awareness on the importance of both vaccinations and adherence to immunization schedule.


2021 ◽  
Vol 8 (1) ◽  
pp. 50-56
Author(s):  
Yuni Waroh Khoirul Waroh

The Covid-19 pandemic gave birth to a new civilization era where people were asked to adapt to this pandemic condition. This also applies to maternal and child health services, especially antenatal care. The highest cause of death in Indonesia in 2019 is due to bleeding, which can be influenced by low hemoglobin levels or what is commonly known as anemia. The purpose of this study was to analyze the relationship between first trimester visits and anemia screening in pregnant women. The research method used was cross sectional, using google form media to fill out questionnaires and screen shots of the MCH book. The statistical test in this study used Pearson. The results showed that there was no relationship between the first trimester visit and anemia screening, which was obtained by the Pearson statistical test value sig = 0.189> 0.05, which means that there was no relationship between the first trimester visit and the examination of hemoglobin levels in pregnant women. The conclusion that can be drawn is that even though we are now entering a new civilization era where there are several regions that implement Large-Scale Social Restrictions and which in Maternal and Child Health services, especially pregnancy examinations, can still be implemented, government policies in the new civilization era during the 1st trimester visit are focused on screening of maternal health conditions for complications in pregnancy, and especially regarding referrals if there are complications in her pregnancy and management of pregnant women with Covid-19, so that this can prevent transmission of Covid-19.


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