scholarly journals Assessment of Drug-Related Problems among Type 2 Diabetic Patients on Follow up at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

2019 ◽  
Author(s):  
Haymen Abdulmalik ◽  
Yohannes Tadiwos ◽  
Nanati Legesse

Abstract Objectives: To assess the drug-related problem among patients with type 2 diabetes at Hiwot Fana Specialized University Hospital Results: In this study, a total of 148 patient medication records were included. More than half, 83(57.4%) were men and the rest 65(42.6%) were women. The mean age of the study participants was 51.26 ± 7.08. Around one third (74.3%) of the participants had urban residency. A total of 127 drug-related problems were identified, of which dosage too low was the most common type of DRP encountered, 46(36.2%), followed by unnecessary drug therapy, 25(19.7%) and ineffective drug therapy, 25(19.7%). 95(64.2%) of the patients had at least one drug-related problem. Among patients with DRP, more than half of them, 59 (62.1%) had a single DRP. Out of the total participants, 85(57.4%) of them were taking one anti-diabetic medication and 63(42.6%) of them dual anti-diabetic medications. Only half of the patients have attained the desired FBG level. There was no patient who had experienced more than two types of drug-related problems at a time. Less than 10% of patients were taking five or more drugs at a time. Key Words: Diabetes mellitus, Drug therapy problem, Hiwot Fana specialized university hospital.

2019 ◽  
Author(s):  
Haymen Abdulmalik ◽  
Yohannes Tadiwos ◽  
Nanati Legesse

Abstract Objectives: To assess drug related problem among patients with type 2 diabetes at Hiwot Fana Specialized University Hospital Results: In this study, a total of 148 patient medication records were included. More than half, 83(57.4%) were males and the rest 65(42.6%) were females. The mean age of the study participant’s was 51.26 ± 7.08. Around one third (74.3%) of the participants had urban residency. A total of 127 drug related problems were identified, of which dosage too low was the most common type of DRP encountered, 47(37%), followed by unnecessary drug therapy, 25(19.7%) and ineffective drug therapy, 25(19.7%). 95(64.2%) of the patients had at least one drug related problem. Among patients with DRP, more than half of them, 59 (62.1%) had a single DRP. Out of the total participants, 85(57.4%) of them were taking one anti-diabetic medication and 63(42.6%) of them dual anti-diabetic medications. Only half of the patients have attained the desired FBG level. There was no patient who had experienced more than two types of drug related problems at a time. Less than 10% of patients were taking five or more drugs at a time. Key Words: Diabetes mellitus, Drug therapy problem, Hiwot fana specialized university hospital.


2019 ◽  
Author(s):  
Haymen Abdulmalik ◽  
Yohannes Tadiwos ◽  
Nanati Legesse

Abstract Objectives: To assess drug related problem among patients with type 2 diabetes at Hiwot Fana Specialized University HospitalResults: In this study, a total of 148 patient medication records were included. More than half, 83(57.4%) were males and the rest 65(42.6%) were females. The mean age of the study participant’s was 51.26 ± 7.08. Around one third (74.3%) of the participants had urban residency. A total of 127 drug related problems were identified, of which dosage too low was the most common type of DRP encountered, 47(37%), followed by unnecessary drug therapy, 25(19.7%) and ineffective drug therapy, 25(19.7%). 95(64.2%) of the patients had at least one drug related problem. Among patients with DRP, more than half of them, 59 (62.1%) had a single DRP. Out of the total participants, 85(57.4%) of them were taking one anti-diabetic medication and 63(42.6%) of them dual anti-diabetic medications. Only half of the patients have attained the desired FBG level. There was no patient who had experienced more than two types of drug related problems at a time. Less than 10% of patients were taking five or more drugs at a time. Key Words: Diabetes mellitus, Drug therapy problem, Hiwot fana specialized university hospital.


Author(s):  
Lamtiar Parulian Parulian ◽  
Ening Listyanti ◽  
Anita Kumala Hati ◽  
Istianatus Sunnah

Hipertensi merupakan masalah kesehatan masyarakat yang umum di negara berkembang. Riskesdas tahun 2013 menyatakan bahwa prevalensi hipertensi secara  umum diindonesia sebesar 26,5% dengan proporsi  serbesar berada di Jawa Tengah yaitu 57,89%. Polifarmasi secara signifikan bisa meningkatkan resiko interaksi obat dimana interaksi obat merupakan salah satu faktor penting dalam drug related problem yang dapat mempengaruhi outcome terapi pasien. Interaksi obat merupakan satu dari delapan kategori masalah terkait obat (drug-related problem) yang dapat mempengaruhi outcome klinis pasien, dengan meningkatnya kompleksitas obat-obat yang digunakan dalam pengobatan saat ini dan kecenderungan terjadinya praktik polifarmasi, maka kemungkinan terjadinya interaksi obat semakin besar. Tujuan dari penelitian ini adalah untuk mengetahui hubungan interaksi obat dalam resep polifarmasi pada pasien yang mendapat terapi obat antihipertensi di instalasi farmasi RSP dr. Ario Wirawan Salatiga. Penelitian ini dilakukan secara retrospektif dengan menggunakan  resep pasien hipertensi rawat jalan di Rumah Sakit Paru Ario Wirawan Salatiga periode Januari-Maret 2019  sebanyak 72 sampel yang termasuk ke dalam kriteria inklusi. Data dianalisis secara deskriptif menggunakan Drug Interaction Facts dan di analisis dengan Spearman test. Diperoleh data bahwa jumlah interaksi obat-obat yang terjadi (51,39%). Pola mekanisme yang terbanyak adalah farmakokinetik (53,97%) dengan tingkat keparahan yang terbanyak adalah minor (42,86%). Hasil menunjukkan adanya korelasi antara jumlah obat dengan kejadian interaksi (r=0,986, p=000) adanya hubungan yang sangat signifikan.Kata kunci : Interaksi Obat, polifarmasi, terapi obat hipertensi.Hypertension is a common problem in developing countries. Based on the basic health research  in 2013, the prevalence of hypertension in Indonesia was 26.5% with a large proportion in Central Java at 57.89%. Polypharmacy can significantly increase the risk of drug interactions where drug interactions are an important factor in drug related problems that can affect the outcome of patient therapy. Drug interaction is one of eight categories of drug-related problems that can affect a patient's clinical outcome. Increasing complexity of the drugs used in current treatment will raise the tendency for polypharmacy to occur, resulting higher chance for the drug interaction possibility.This study is aimed to find relationship of drug interactions with polypharmacy prescriptions by patients receiving antihypertensive drug therapy in Dr. Ario Wirawan Hospital. This study was conducted retrospectively using the outpatient prescription that entered the inclusion criteria at Dr. Ario Wirawan Hospital Salatiga. A total of 72 samples that included in the inclusion criteria. Data were analyzed descriptively using Drug Interaction Facts and analyzed by Spearman test. Result showed that the number of drug interactions that occurred (51,39%). The most mechanism pattern of the drug interaction was pharmacokinetics (53,97%) with the highest severity level being minor (42,86%). This study showed that there is a a very significant correlation between the number of drugs and interactions (r = 0.986, p = 000).Keywords : Drug interactions, polypharmacy, hypertension drug therapy  


2018 ◽  
Vol 9 (2) ◽  
pp. 58
Author(s):  
Amelia Lorensia ◽  
Ernie Gorisalam

Liver cirrhosis usually causes glucose intolerance/disturbance that leads to diabetes mellitus type 2. However diabetes mellitus type 2 is a risk factor on liver syrosis. The drug therapy can be quiet complex because of the liver damage and the consumption of the hepatotoxic hypoglichemic oral drug use. This research is aimed to evaluate the possibility of the drug-related problem (DRP) on the drug therapy of diabetes mellitus type 2 on patients with liver cirrhosis. This research is non-experimental with the descriptive analysis designed retrospectivally. The total sample used in this research is 51 patients. The results of the drug related problem (DRP) according to the problem faced: Effect of drug treatment not optimal (P1.2) 54,90%, Adverse drug event (non-allergic) (P2.1) 3,92%. DRP Results according to the cause: Inappropriate drug (included contra-indicated) (C1.1) 23,52%, Pharmacokinetic problem requiring dose adjustment (C3.6) 1.96%, Drug underused/ under-administered (deliberately) (C5.2) 39,21%. DRP which happens most are P1.2 and C5.2, anti-diabetic drugs that is involved in the DRP according to problem is insulin and sulfonilurea causes, the clinical outcome for the DRP according to this is nothing happened.


2021 ◽  
Vol 9 (2) ◽  
pp. 134-142
Author(s):  
Akhmad Rokiban ◽  
◽  
Dwiauliaramdini Dwiauliaramdini ◽  
Sitijuwariyah Sitijuwariyah

Abtract Diabetes mellitus (DM) is a serious chronic disease that occurs because the pancreas does not produce enough insulin or when insulin is not use effectively in the body. This study aims to analyze the incidence of Drug Related Problems (DRPs) and find out the category of DRPs in outpatients with a diagnosis of type 2 diabetes mellitus at UPT Puskesmas Gedong Air Inpatient for the Bandar Lampung. This research is a nonexperimental research with a descriptive design taken retrospectively. The sampling technique used in this study is total sampling based on the patient's medical record data. Data were analyzed using the classification of DRPs according to Cipolle 2004, then using Medscape Tools as a tool to check potential drug interactions. The results of this study were 61 patients including 29 patients (46%) with DRPs and 33 patients (54%) without DRPs. The number of male patients is 25 patients and the number of female patients is 36 patients with age range 25-45 and 46-65. A total 52 patien Type 2 Diabetes Mellitus have cormobid and 9 patients without comorbid. DRP categories that occur include drugs without indication as much (8%), indications without drugs as much as (15%), and potential drug interactions (48%). The conclusion in this study is that Drug Related Problems (DRPs) have occurred in outpatients diagnosed with type 2 diabetes mellitus in UPT Puskesmas Gedong Air Inpatient with the highest DRPs category is the potential for drug interactions (48%). Key words: Diabetes Mellitus Type 2, Drug Related Problems


2021 ◽  
Vol 24 (2) ◽  
pp. 97
Author(s):  
Foglia, A.

With the outbreak of the COVID-19 pandemic and the resulting restrictions, telemedicine has enabled healthcare to be provided to patients with chronic diseases, although with some restrictions. During the lockdown The Campania region was the first to order (03/27/2020), to protect the health of citizens suffering from diabetes mellitus, the use of telemedicine and a tele-health service was activated in our clinics. At the end of the consultation, a survey was submitted to our diabetic patients in order to evaluate their opinion about the telemedicine experience in comparison with the traditional clinic visit. 100% of both type 1 and type 2 patients consider the telemedicine visit adequate, 89.2% of types 1 and 75.9% of types 2 consider the two forms of visit absolutely overlapping from a professional point of view, and even 6.9% of type 2, but none of type 1, considers the tele-visit more effective than the traditional visit. However, only 44.8% (type 2 diabetic patients) and 13,5%% (type 1 diabetic patients) expressed a preference for telemedicine visits over traditional visits. Telemedicine has allowed continuity of care for diabetic patients despite the difficulties of this emergency time. We believe that the opinion of patients and health care professionals on the telemedicine experience can be useful to assess the limitations and advantages in order to improve and enhance the use of this method. KEY WORDS diabetes mellitus; telemedicine system; survey.


Author(s):  
Surya Yuli Astuti ◽  
Mawardi Ihsan ◽  
Fita Rahmawati

Drug-Related Problems have been associated to blood glucose control along with the morbidity and mortality of type 2 diabetes patients through previous studies. However, studies that associate Length of Stay (LOS) with DRPs in type 2 diabetes patients have not been done. The study that had been done was to associate between LOS and Medication Errors (ME). Medication errors include DRPs because other researchers state that errors are also kind of problem. This study was aimed to identify Drug-Related Problems (DRPs) and to associate between DRPs and LOS in type 2 diabetes patients who were hospitalized. This study was a prospective observation study with a cross-sectional design. Sample collection was carried out by consecutive sampling method in type 2 diabetic patients hospitalized in internal medicine ward in one academic hospital in Yogyakarta. Data analysis was done descriptively to see DRPs description and the association between DRPs and LOS was analyzed using Chi-square or Fisher's exact test whenever Chi-square test conditions were not met. Data collection was carried out in January till April 2018. The results showed that the DRPs in hospitalized type 2 diabetic patients were 80.56% with unnecessary drug therapy occurring at 34.72%; dosage too low of 25%; needs additional drug therapy 13.38%; dosage too high 12.5%; ineffective drug 11.11%; and there was no association seen between DRPs and LOS.


2019 ◽  
pp. 30-40
Author(s):  
Ruri Renggani Sandra ◽  
Della Midi Wardhani ◽  
Woro Supadmi

   Autism spectrum disorders (ASD) adalah gangguan perkembangan saraf dengan penyebab yang kompleks dari banyak fakor Penggunaan obat pada pasien autis harus dimonitoring untuk mencegah terjadinya drug related problems. Intervensi farmasis dengan mengidentifikasi kejadian drug related problem adalah kegiatan pelayanan asuhan kefarmasian untuk meningkatkan keberhasilan terapi. Penelitian ini adalah observasional dengan pengumpulan data secara retrospektif berdasarkan data rekam medik. Evaluasi kejadian drug related problems meliputi indikasi yang tidak diterapi, terapi tanpa indikasi, pemilihan obat yang tidak tepat, overdosis, under dosis, adverse drug reactions dan interaksi obat. Literatur yang digunakan sebagai acuan adalah Drug Information Handbook, 18thed, Stockley Drug Interaction, Drugs Interaction Facts 2001, dan Pharmacotherapy A Pathophysiologic Approach 2005 dan jurnal yang relevan.   Hasil penelitian diperoleh pasien dengan jenis kelamin laki-laki 20 pasien (77%), perempuan 6 pasien (23%). Usia antara 6-11 tahun yaitu 15 pasien (58%), 1-5 tahun terdapat 9 pasien (34%), usia <1 tahun dan 12-17 tahun masing-masing sebanyak 1 pasien (4%). Penyakit penyerta ISPA merupakan kasus yang paling banyak terjadi, terbanyak kedua adalah epilepsi dan gastroenteritis akut (GEA). Kejadian DRPs Indikasi tidak diterapi 9%, Terapi tanpa indikasi 9%, Pemilihan obat tidak tepat 9%, Over dosis 31%, Under dosis 33% dan interaksi obat 9%.   Terdapat 24 pasien ( 92,3%) yang mengalami DRPs potensial dan 2 pasien (7,7%) yang tidak mengalami. Kriteria DRPs dengan persentase tertinggi adalah under dosis sebanyak 33% dan over dosis sebanyak 31%.


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