scholarly journals Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

2019 ◽  
Author(s):  
Jian OU-YANG ◽  
Chun-Hua BEI ◽  
Hua-Qin LIANG ◽  
Bo HE ◽  
Jin-Yan CHEN ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Blood Donors ◽  
Average Treatment Effect ◽  
Controlled Study ◽  
Randomized Controlled ◽  
Donation Rate ◽  
Sms Reminder ◽  
Sms Reminders ◽  
Telephone Calls ◽  
Telephone Group

Abstract Background: Recruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for re-recruitment of inactive blood donors. Methods: This single-centre, non-blinded, parallel randomized controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to one of two intervention groups (telephone call or short message service [SMS] communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome was re-donation rate, and rates in different groups were compared by intention-to-treat (ITT) analysis and estimation of the average treatment effect on the treated (ATT). Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls and SMS reminders on re-recruitment. Results: ITT analysis revealed no significant differences in the re-donation rate among the three groups. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors. Conclusions: Interventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder.

scholarly journals Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

2019 ◽  
Author(s):  
Jian OU-YANG ◽  
Chun-Hua BEI ◽  
Hua-Qin LIANG ◽  
Bo HE ◽  
Jin-Yan CHEN ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Treatment Effect ◽  
Blood Donors ◽  
Average Treatment Effect ◽  
Randomized Controlled ◽  
Average Treatment ◽  
Sms Reminder ◽  
Sms Reminders ◽  
Telephone Calls ◽  
Telephone Group

Abstract Background: Recruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for re-recruitment of inactive blood donors. Methods: This single-centre, non-blinded, parallel randomized controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to either one of two intervention groups (received telephone or short message service [SMS] communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome were re-donation rates, compared by intention-to-treat (ITT) analysis, average treatment effect (ATE) and average treatment effect on the treated (ATT) estimations. Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls versus SMS reminders on re-recruitment. Results: ITT analysis discovered no significant differences in the re-donation rate among the three groups. ATE estimation showed that participants who were randomly assigned to the telephone group were more likely to re-donate than those in the SMS group. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors. Conclusions: Interventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder.

Cost-effectiveness of pharmaceutical care on patients undergoing maintenance hemodialysis – a multicenter randomized controlled study

2018 ◽  
Vol 130 (7) ◽  
pp. 621-626 ◽  
Author(s):  
Uday Venkat Mateti ◽  
Anantha Naik Nagappa ◽  
Ravindra Prabhu Attur ◽  
Shankar Prasad Nagaraju ◽  
Dharshan Rangaswamy
Keyword(s):  
Cost Effectiveness ◽  
Pharmaceutical Care ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Maintenance Hemodialysis ◽  
Randomized Controlled

The effects of text messaging for promoting the retention of the first‐time blood donors, a randomized controlled study ( TEXT study)

Transfusion ◽  
2020 ◽  
Vol 60 (10) ◽  
pp. 2319-2326
Author(s):  
Chontara Pongsananurak ◽  
Lalita Norasetthada ◽  
Adisak Tantiworawit ◽  
Ekarat Rattarittamrong ◽  
Thanawat Rattanathammethee ◽  
...  
Keyword(s):  
Text Messaging ◽  
Blood Donors ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled ◽  
First Time ◽  
Text Study

scholarly journals Korean Model for Post-acute Comprehensive rehabilitation (KOMPACT): The Study Protocol for a Pragmatic Multicenter Randomized Controlled Study on Early Supported Discharge

2021 ◽  
Vol 12 ◽  
Author(s):  
Won Kee Chang ◽  
Won-Seok Kim ◽  
Min Kyun Sohn ◽  
Sungju Jee ◽  
Yong-Il Shin ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Acute Stroke ◽  
Study Protocol ◽  
Transitional Care ◽  
Controlled Trial ◽  
Controlled Study ◽  
Care Model ◽  
Stroke Patients ◽  
Randomized Controlled ◽  
Early Supported Discharge

Introduction: Early supported discharge (ESD) is a transitional care model aimed at facilitating post-acute stroke patients' discharge to home. Previous studies have demonstrated that ESD provides equivalent patient and caregiver outcomes with superior cost-effectiveness compared to conventional rehabilitation (CR). This study intends to examine the feasibility of ESD in Korea.Methods and Analysis: This study is designed as a multicenter assessor-blinded, randomized controlled trial. Ninety post-acute stroke patients with mild to moderate disability (modified Rankin Scale 1–3) will be recruited from three university hospitals (30 patients per hospital) in Korea and allocated to either the ESD group or the CR group in a 1:1 ratio. Patients in the ESD group will receive individualized discharge planning and goal setting, a 4-week home-based rehabilitation program, and liaison service to community-based resources by a multidisciplinary team. Patients in the CR group will receive rehabilitation practices according to their current hospital policy.Outcomes: The primary outcome is the Korean version of the modified Barthel Index, and the primary endpoint was post-onset 3 months. Clinical outcomes, patient/caregiver reported outcomes, and socioeconomic outcomes will be measured at baseline, 1 month after discharge, 2 months after discharge, and 3 months after onset.Discussion: The efficacy and cost-effectiveness of ESD can vary according to the healthcare system and sociocultural aspects. To establish ESD as an alternative transitional care model for post-acute stroke patients in Korea, its feasibility needs to be examined in prior. This study will add evidence on the applicability of ESD in Korea.Ethical Considerations: The study protocol was reviewed and approved by the Institutional Review Board of Seoul National University Bundang Hospital (IRB number B-2012/654-308). The study protocol was registered at ClinicalTrials.gov (Identifier NCT04720820). Disseminations will include submission to peer-reviewed journals and presentations at conferences.

scholarly journals Combined evaluation of long-lasting insecticidal nets, house screening and push-pull technology as appropriate interventions for integrated management of malaria vectors and cereal pests in Ethiopia: study protocol for household randomized controlled trial

2021 ◽  
Author(s):  
Abebe Asale ◽  
Menale Kassie ◽  
Zewdu Abro ◽  
Bayu Enchalew ◽  
Aklilu Belay ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Indoor Residual Spraying ◽  
Clinical Malaria ◽  
Cost Effectiveness Analysis ◽  
Controlled Study ◽  
Crop Pests ◽  
Randomized Controlled ◽  
Effectiveness Analysis ◽  
The Impact ◽  
Long Lasting Insecticidal Nets

Abstract Introduction: The combined application of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has led to mixed results (Significant reduction vs no impact) on malaria burden. Other studies have attempted to study the combined effects of house screening (HS) and LLINs have demonstrated a reduction in indoor vector densities and malaria when the interventions are combined. In addition to malaria vectored by mosquitoes, farmers living in rural settings face challenges from crop pests, which significantly reduce agricultural productivity and negatively impact their food security. Thus, addressing the coexisting risks of malaria and crop pests could contribute to improved livelihood of communities. Design: A three armed household, cluster-randomized, controlled study will be conducted to assess the impact of HS, LLINs and PPT against clinical malaria in children than LLINs alone in Ethiopia. The unit of randomization will be the household, which include a house and its occupants. A total of 663 households will be enrolled in this study. All the households will receive the LLINs. Then other treatments will be overlaid according to the randomization sequence. Thus, 246 households will receive HS, and 250 households will receive HS and PPT before the commencement of clinical follow-up. The rest 167 houses which received LLINs only will be used as control. One child aged not more than 14 years will be enrolled from each household and followed for clinical malaria using active case detection to estimate malaria incidence for two malaria transmission seasons. Results: Episodes of clinical malaria, the prevalence of anaemia, density of malaria vector mosquitoes, sporozoite infection rate, crop infestation rate due to stem borer and fall army worm, crop yield gain, livestock productivity and cost effectiveness analysis will be the end points of this study. Socio-economic, social demographic, cost-effectiveness analysis will be conducted using qualitative and participatory methods to explore the acceptability of HS and PPT. Conclusion Documenting the combined impact of LLINs, HS and PPT on the prevalence of clinical malaria and crop pest damage will be the first of its kind and will provide deep insight and evidence base for forging collaborations between health and agriculture sectors. Trial Registration: The protocol was registered online on Date 28/05/2020 on sight www.pactr.org With registration No: PACTR202006878245287.

scholarly journals Efficiency of Text Message Contact on Medical Safety in Outpatient Surgery: Retrospective Study (Preprint)

2019 ◽  
Author(s):  
Jeremy Peuchot ◽  
Etienne Allard ◽  
Bertrand Dureuil ◽  
Benoit Veber ◽  
Vincent Compère
Keyword(s):  
Conversion Rate ◽  
Outpatient Surgery ◽  
University Hospital ◽  
Controlled Study ◽  
Full Time ◽  
Medical Safety ◽  
Hospitalization Costs ◽  
Sms Reminder ◽  
Sms Reminders ◽  
The Impact

BACKGROUND Establishing pre- and postoperative contact with patients is part of successful medical management in outpatient surgery. In France, this is mostly done via telephone. Automated information with short message service (SMS) reminders might be an interesting alternative to increase the rate of compliance with preoperative instructions, but no study has shown the safety of this approach. OBJECTIVE The objective of this study was to evaluate the impact of pre- and postoperative automated information with SMS reminders on medical safety in outpatient surgery. METHODS We conducted a retrospective, single-center, nonrandomized, controlled study with a before-after design. All adult patients who had outpatient surgery between September 2016 and December 2017 in our university hospital center were included. Before April 2017, patients were contacted by telephone by an outpatient surgery nurse. After April 2017, patients were contacted by SMS reminder. All patients were contacted the day before and the day after surgery. Patients contacted by SMS reminder were also contacted on day 7 after surgery. The primary end point was the conversion rate to full-time hospitalization. Secondary end points were hospitalization causes (anesthetic, surgical, organizational) and hospitalization costs. RESULTS A total of 4388 patients were included, 2160 before and 2228 after the introduction of SMS reminders. The conversion rate to full-time hospitalization was 34/4388 (0.77%) with a difference between SMS group (8/2228, 0.36%) and telephone group (26/2160, 1.20%). The cost of SMS reminders was estimated as half that of telephone calls. CONCLUSIONS In this work, we report a decrease in the rate of conversion to full-time hospitalization with the use of pre- and postoperative SMS reminders. This new approach could represent a safe and cost-effective method in an outpatient surgery setting.

Economic evaluation of a nurse-led home and clinic-based secondary prevention programme to prevent progressive cardiac dysfunction in high-risk individuals: The Nurse-led Intervention for Less Chronic Heart Failure (NIL-CHF) randomized controlled study

2017 ◽  
Vol 17 (5) ◽  
pp. 439-445 ◽  
Author(s):  
Shoko Maru ◽  
Joshua Byrnes ◽  
Melinda J Carrington ◽  
Yih-Kai Chan ◽  
Simon Stewart ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cost Effectiveness ◽  
Chronic Heart Failure ◽  
Cardiac Dysfunction ◽  
Standard Care ◽  
Controlled Study ◽  
Randomized Controlled ◽  
Life Years ◽  
Hospitalization Costs ◽  
The Cost

Objective: The objective of this study was to assess the cost-effectiveness of a long-term, nurse-led, multidisciplinary programme of home/clinic visits in preventing progressive cardiac dysfunction in patients at risk of developing de novo chronic heart failure (CHF). Methods: A trial-based analysis was conducted alongside a pragmatic, single-centre, open-label, randomized controlled trial of 611 patients (mean age: 66 years) with subclinical cardiovascular diseases (without CHF) discharged to home from an Australian tertiary referral hospital. A nurse-led home and clinic-based programme (NIL-CHF intervention, n = 301) was compared with standard care ( n=310) in terms of life-years, quality-adjusted life-years (QALYs) and healthcare costs. The uncertainty around the incremental cost and QALYs was quantified by bootstrap simulations and displayed on a cost-effectiveness plane. Results: During a median follow-up of 4.2 years, there were no significant between-group differences in life-years (−0.056, p=0.488) and QALYs (−0.072, p=0.399), which were lower in the NIL-CHF group. The NIL-CHF group had slightly lower all-cause hospitalization costs (AUD$2943 per person; p=0.219), cardiovascular-related hospitalization costs (AUD$1142; p=0.592) and a more pronounced reduction in emergency/unplanned hospitalization costs (AUD$4194 per person; p=0.024). When the cost of intervention was added to all-cause, cardiovascular and emergency-related readmissions, the reductions in the NIL-CHF group were AUD$2742 ( p=0.313), AUD$941 ( p=0.719) and AUD$3993 ( p=0.046), respectively. At a willingness-to-pay threshold of AUD$50,000/QALY, the probability of the NIL-CHF intervention being better-valued was 19%. Conclusions: Compared with standard care, the NIL-CHF intervention was not a cost-effective strategy as life-years and QALYs were slightly lower in the NIL-CHF group. However, it was associated with modest reductions in emergency/unplanned readmission costs.

scholarly journals Effect of Mobile Phone Text Message Reminders on Routine Immunization Uptake in Pakistan: Randomized Controlled Trial (Preprint)

2016 ◽  
Author(s):  
Abdul Momin Kazi ◽  
Murtaza Ali ◽  
Khurram Zubair ◽  
Hussain Kalimuddin ◽  
Abdul Nafey Kazi ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Mobile Phone ◽  
Standard Care ◽  
Controlled Trial ◽  
Text Messages ◽  
Vaccine Uptake ◽  
Routine Immunization ◽  
Randomized Controlled ◽  
Sms Reminder ◽  
Sms Reminders

BACKGROUND Improved routine immunization (RI) coverage is recommended as the priority public health strategy to decrease vaccine-preventable diseases and eradicate polio in Pakistan and worldwide. OBJECTIVE The objective of this study was to ascertain whether customized, automated, one-way text messaging (short message service, SMS) reminders delivered to caregivers via mobile phones when a child is due for an RI visit can improve vaccination uptake and timelines in Pakistan. METHODS This was a randomized controlled trial, conducted in an urban squatter settlement area of Karachi, Pakistan. Infants less than 2 weeks of age with at least one family member who had a valid mobile phone connection and was comfortable receiving and reading SMS text messages were included. Participants were randomized to the intervention (standard care + one-way SMS reminder) or control (standard care) groups. The primary outcome was to compare the proportion of children immunized up to date at 18 weeks of age. Vaccine given at 6, 10, and 14 weeks schedule includes DPT-Hep-B-Hib vaccine (ie, diphtheria, pertussis, and tetanus; hepatitis B; and Haemophilus influenza type b) and oral poliovirus vaccine (OPV). Data were analyzed using chi-square tests of independence and tested for both per protocol (PP) and intention-to-treat (ITT) analyses. RESULTS Out of those approached, 84.3% (300/356) of the participants were eligible for enrollment and 94.1% (318/338) of the participants had a working mobile phone. Only children in the PP analyses, who received an SMS reminder for vaccine uptake at 6 weeks visit, showed a statistically significant difference (96.0%, 86/90 vs 86.4%, 102/118; P=.03).The immunization coverage was consistently higher in the intervention group according to ITT analyses at the 6 weeks scheduled visit (76.0% vs 71.3%, P=.36). The 10 weeks scheduled visit (58.7% vs 52.7%, P=.30) and the 14 weeks scheduled visit (31.3% vs 26.0%, P=.31), however, were not statistically significant. CONCLUSIONS Automated simple one-way SMS reminders in local languages might be feasible for improving routine vaccination coverage. Whether one-way SMS reminders alone can have a strong impact on parental attitudes and behavior for improvement of RI coverage and timeliness needs to be further evaluated by better-powered studies and by comparing different types and content of text messages in low-and middle-income countries (LMICs). CLINICALTRIAL ClinicalTrials.gov NCT01859546; https://clinicaltrials.gov/ct2/show/NCT01859546 (Archived by WebCite at http://www.webcitation.org/6xFr57AOc)

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