The effect of initial lens diopter on myopia control by orthokeratology in Teenagers A retrospective Beijing Study

Abstract Background To investigate the effect of initial refractive error on the control of myopia by orthokeratology. Methods Retrospective study. Data were analyzed from 78 patients (156 eyes) who underwent orthokeratology in Beijing Children's Hospital from January 2014 to April 2018. The changes of axial length and diopter after wearing the lenses were measured. Patients were divided into six groups according to refractive error: <-1.00D, -1.00~ -2.00D, -2.00D~ -3.00D, -3.00D~ -4.00D, -4.00D~ -5.00D and -5.00~ -6.00D. A mixed-effect model was used to analyze the relevant data. At the same time, the interaction item between diopter and wearing time was analyzed, and the influence of gender was corrected. Results Patients averaged 12.9±2.161 years old. Two years after wearing orthokeratology lenses, there was a statistically significant difference with the interaction item between refractive error and wearing time in each group. The estimated values were 0.0631 for the right eye and 0.053 for the left eye. Orthokeratology lenses controlled the progression of myopia well, but the reduction depended on the initial diopters. Binocular axial length examination didn’t show statistically significant difference with the interaction item. Axial length increased with time, and the magnitude of increase did not differ among groups. However, the increase in the axial length of the male more than that of the female.Conclusion Initial refractive errors have a significant impact on the control of myopia by orthokeratology. The less severe myopia patient demonstrated a more pronounced benefits after wearing orthokeratology lenses. Key words: refractive error; myopia; orthokeratology

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The effect of initial lens diopter on myopia control by orthokeratology in Teenagers A retrospective Beijing Study

10.21203/rs.2.16212/v2 ◽

2019 ◽

Author(s):

Jifeng Yu ◽

Wei Shi ◽

Xue Liu ◽

Si-Yuan Li ◽

Li Li

Keyword(s):

Refractive Error ◽

Axial Length ◽

Study Data ◽

Mixed Effect Model ◽

Mixed Effect ◽

Effect Model ◽

Significant Difference ◽

The Right ◽

First Time ◽

Myopia Control

Abstract Background To investigate the effect of initial refractive error on the control of myopia by orthokeratology. Methods Retrospective study. Data were analyzed from 78 patients (156 eyes) who underwent orthokeratology in Beijing Children's Hospital from January 2014 to April 2018. The changes of axial length and diopter after wearing the lenses were measured. Patients were divided into six groups according to refractive error: <-1.00D, -1.00~ -2.00D, -2.00D~ -3.00D, -3.00D~ -4.00D, -4.00D~ -5.00D and -5.00~ -6.00D. A mixed-effect model was used to analyze the relevant data. At the same time, the interaction item between diopter and wearing time ( the first time when children wear orthokeratology lens) was analyzed, and the influence of gender was corrected. Results Patients averaged 12.9±2.161 years old. Two years after wearing orthokeratology lenses, there was a statistically significant difference with the interaction item between refractive error and wearing time in each group. The estimated values were 0.0631 for the right eye and 0.053 for the left eye. Orthokeratology lenses controlled the progression of myopia well, but the reduction depended on the initial diopters. Binocular axial length examination didn’t show statistically significant difference with the interaction item. Axial length increased with time, and the magnitude of increase did not differ among groups. However, the increase in the axial length of the male more than that of the female. Conclusion Initial refractive errors have a significant impact on the control of myopia by orthokeratology. The less severe myopia patient demonstrated a more pronounced benefits after wearing orthokeratology lenses.

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Spectacle Lenses With Slightly Aspherical Lenslets for Myopia Control: Clinical Trial Design and Baseline Data

10.21203/rs.3.rs-847219/v1 ◽

2021 ◽

Author(s):

Junhong Chen ◽

Ran Zhuo ◽

Jiayan Chen ◽

Adeline Yang ◽

Ee Woon Lim ◽

...

Keyword(s):

Clinical Trial ◽

Visual Acuity ◽

Refractive Error ◽

Axial Length ◽

Baseline Data ◽

Major Public Health Problem ◽

Spherical Equivalent ◽

Single Vision ◽

Significant Difference ◽

Myopia Control

Abstract Objectives: Myopia is a major public health problem and it is essential to find safe and effective means to control its progression. The study design and baseline data are presented for a one-year prospective, double-masked, cross-over, randomized clinical trial evaluating the efficacy of single vision spectacle lenses with concentric rings of slightly aspherical contiguous lenslets technology (SAL) on myopia control. Methods: One hundred 8- to 13-year old Chinese children with a refractive error of -0.75 D to -4.75 D were assigned into two groups. In Group 1, SAL then single vision lenses were each worn for 6 months, and Group 2 wore the lenses in the reversed order. Primary outcomes are axial length and spherical equivalent of cycloplegic refractive error. Secondary outcomes include corneal thickness, anterior chamber depth, lens thickness, visual acuity, and lens adaptation.Results: No significant differences in baseline parameters (cycloplegic spherical equivalent, axial length, age) were found between groups (0.49 < p < 0.94). All children adapted well to the test lenses and there was no significant difference in visual acuity between the SAL and single vision lenses (p = 0.27).Conclusions: The children in the two well balanced groups had comparable visual acuity and adapted well to the test lenses. These results imply the visual acuity can be well improved by SAL lens. Clear visual acuity provide the assurance for good compliance in this longitudinal study.

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The Effect of Anthropometry on Refractive Error and Ocular Biometry in Children with β Thalassemia Major

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.6280 ◽

2021 ◽

Vol 9 (T3) ◽

pp. 64-67

Author(s):

Aryani Atiyatul Amra ◽

Fithria Aldy ◽

Bidasari Lubis ◽

Elyani Rahman

Keyword(s):

Anterior Chamber ◽

Refractive Error ◽

Axial Length ◽

Anterior Chamber Depth ◽

Thalassemia Major ◽

University Hospital ◽

Refractive Errors ◽

Cross Sectional ◽

Ocular Biometry ◽

The Right

AIM: The objective of the study was to evaluate the effect of anthropometry on refractive error and ocular biometry in children with β-thalassemia major. METHOD: This study was an analytical observational with a cross-sectional design which conducted in 1 day care thalassemia pediatric Department and Ophthalmology Department of North Sumatera University Hospital from February to April 2019. The study included 44 children with β-thalassemia major. RESULTS: Anthropometric analysis of refractive errors did not show a significant correlation, whereas anthropometric analysis on biometry showed a significant correlation between height and axial length of the right eye (p = 0.004) and left eye (p = 0.043), then showed significant correlations between height and anterior chamber depth of the right eye (p = 0.027) and left eye (p = 0.016). CONCLUSION: Height affects the axial length and anterior chamber depth, but there are no anthropometric variables that affect refractive errors in this study.

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