Numerical Simulation Study of Proppant Transport in Cross Fractures

Hydraulic fracturing technology is an important means to stimulate unconventional reservoirs, and the placement morphology of proppant in cross fractures is a key factor affecting the effect of hydraulic fracturing. It is very important to study the proppant transport law in cross fractures. In order to study the proppant transportation law in cross fractures, based on the CFD-DEM method, a proppant transport model in cross fractures was established. From the two aspects of the flow field in the fractures and the morphology of the proppant dune, the influence of the natural fracture approach angle, the fracturing fluid viscosity and injection rate on the proppant transport is studied. Based on the principle of hydropower similarity, the conductivity of proppant dune under different conditions is quantitatively studied. The results show that the natural fracture approach angle affects the distribution of proppant and fracturing fluid in natural fractures, and further affects the proppant placement morphology in hydraulic fractures and natural fractures. When the fracturing fluid viscosity is low and the displacement is small, the proppant forms a "high and narrow" dune at the entrance of the fracture. With the increase of the fracturing fluid viscosity and injection rate, the proppant settles to form a "short and wide" placement morphology. Compared with the natural fracture approach angle, the fracturing fluid viscosity and injection rate have a more significant impact on the conductivity of proppant dune. This paper investigated the proppant transportation in cross fractures, and quantitatively analyzes the conductivity of proppant dunes with different placement morphology. The results of this study can provide theoretical guidance for the design of hydraulic fracturing.

Elastic Material Damage of Rotational Atherectomy and Orbital Atherectomy: An in Vitro Assessment

PurposeRotational atherectomy (RA) and orbital atherectomy (OA) are effective procedures for severe calcified coronary artery disease. Nonetheless, vessel perforation remains an adverse complication of these procedures. This study aimed to evaluate factors affecting elastic material damage caused by RA and OA.MethodsAn in vitro assessment was conducted in which the damage to the rubber latex, an elastic material, after RA was evaluated under various conditions, including burr rotational speed (100,000–220,000 rotations per minute), approaching curve, burr size (1.25 mm, 1.75 mm, and 2.0 mm), and fluid viscosity (water and low-molecular weight dextran). Similarly, the rubber latex damage after OA was evaluated in the same experimental system under various conditions, including crown rotational speed, approaching curve, and fluid viscosity.ResultsIn RA, the rubber latex was damaged at lower rotational speeds (p = 0.003), tighter approaching curves (p < 0.0001), and lower fluid viscosity (p = 0.03). In OA, the rubber latex was generally severely damaged.ConclusionA higher rotational speed, coaxial approach for the wall, and higher viscosity contributed to lesser elastic material damage in RA. The safety mechanism for elastic material in OA proved less effective.

Experimental Study on Diverter Transport Through Perforations in Multicluster Fracturing of Horizontal Well

Summary Temporary plugging and diverting fracturing of the horizontal well is the primary option to promote production for tight reservoirs. Successful entry of diverters into the perforation is the basis and prerequisite for effective plugging. However, the transport behavior of the diverter during multicluster fracturing remains unclear. In this paper, we build a large-scale diverter transport experimental system, capable of conducting experiments with large flow rates and high pressures. The concerned factors include the injection rate, perforation flow ratio (PFRO), fluid viscosity, and perforation angle. The results show that the diverter transport effect is significantly different because of different flow distribution among perforations. Also, the diverter can enter the perforation only when the flow rate of the perforation reaches a certain value. In addition, the minimum critical PFRO has an “oblique L-shaped” relationship with the injection rate. Although it is difficult for the diverter to enter the perforation on the high side of the horizontal wellbore, increasing the viscosity of the carrying fluid or using a multidensity mixed diverter can effectively solve this problem. Furthermore, the field case shows that the experimentally obtained diverter transport pattern can be applied to the field to predict the location of the diverter and improve the temporary plugging effect. The findings of this work lay a theoretical foundation for subsequent temporary plugging and diverting fracturing control.

Wells production viscosity measurement results application for pumping equipment operation diagnostics

The article is devoted to the diagnostics of the well pumping equipment operation using wells production viscosity measurement results obtained by the developed field device VNP 1-4, 0-90. The method for making measurements with a field oil viscometer was developed in accordance with the provisions of GOST R 8.563, GOST R ISO 5725-2. It has gained certification and entered the State Register of the Russian Federation. On the basis of preliminary laboratory studies of oils viscosity from the group of fields of LLC UK «Sheshmaoil», a formula was obtained for the dependence of oil emulsions viscosity on temperature and the content of formation water in them. Viscosity measurements obtained with the developed device in field conditions have shown the applicability of the method for calculating the watered oil viscosity.The application of the results of measuring the watered oil viscosity at the wellhead allows diagnosing the downhole sucker rod pump unit operation based on the construction of a dynamic model of its operation. Keywords: equipment diagnostics; water cut; temperature; fluid viscosity; dynamic model; sucker rod pump.

Assessment of chimeric antigen receptor T (CAR-T) cytotoxicity by droplet microfluidics in vitro

Chimeric antigen receptor T (CAR-T) cells are cytotoxic T cells engineered to specifically kill cancer cells expressing specific target receptor(s). Prior CAR-T efficacy tests include CAR expression analysis by qPCR or ELISA, in vitro measurement of interferon-gamma; (IFNgamma) or interleukin-2 (IL-2), and xenograft models. However, the in vitro measurements did not reflect CAR-T cytotoxicity, whereas xenograft models are low throughput and costly. Here we presented a robust in vitro droplet microfluidic assay for CAR-T cytotoxicity assessment. This method not only enabled assessment of CAR-T cytotoxic activity under different fluid viscosity conditions, but also facilitated measurement of CAR-T expansion and dissection of mechanism of action via phenotype analysis in vitro. Furthermore, our data suggested that label-free cytotoxicity analysis is feasible by acquiring data before and after treatment. Hence, this study presented a novel in vitro method for assessment of cellular cytotoxicity that could potentially be applied to any cell-kill-cell experiment with varying solvent composition.

Rheological Properties of Magnetic Field-Assisted Thickening Fluid and High Efficiency Spherical Polishing of ZrO2 Ceramics

Shear thickening polishing technology using non-Newtonian polishing fluid is a low-cost, low-damage polishing method for the ultra-precision machining of complex curved surfaces. However, the shortcomings of traditional shear thickening polishing fluid in polishing efficiency and fluid viscosity controllability limit its further application., a novel weak magnetic field-assisted shear thickening polishing fluid (WMFA-STPF) containing carbonyl iron particles (CIPs) is presented in this study, which utilizes its weak magnetorheological effect to strengthen the shear thickening phenomenon. The rheological characteristics of the WMFA-STPF samples were investigated. The results show that WMFA-STPF has good fluidity in the low shear rate range and better thickening characteristics in the working shear rate range. In order to verify the high efficiency, high quality and high uniformity polishing ability of the weak magnetic field-assisted shear thickening polishing technology for the spherical surface of zirconia ceramic workpiece, the contrast polishing experiment was designed and finished. The experimental results show that the weak magnetic field-assisted thickening effect can achieve high efficiency and high quality polishing of hard and brittle ceramics. After 75 min polishing, the surface damage was effectively improved and eliminated, the surface quality and uniformity were greatly improved, and the material removal rate reached 7.82 μm/h, increased by 156%.

Monitoring of Liquid Viscosity for Viscous Dampers through a Wireless Impedance Measurement System

Viscous dampers are a type of seismic damping equipment widely used in high-rise buildings and bridges. However, the viscosity of the damping fluid inside the viscous damper will change over time during its use, which significantly reduces the seismic performance of the viscous damper. Hence, it is necessary to monitor the viscosity of the fluid inside the damper over its service life. In this paper, a damping fluid viscosity monitoring method based on wireless impedance measurement technology is proposed. A piezoelectric sensor is installed in a damper cylinder specimen, and the viscosity of the damping fluid is determined by measuring the piezoelectric impedance value of the sensor. In this study, 10 samples of damping fluids with different viscosities are tested. In order to quantitatively correlate damping fluid viscosity and electrical impedance, a viscosity index (VI) based on the root mean square deviation (RMSD) is proposed. The experimental results show that the variation of the real part in the impedance signal can qualitatively determine the damping fluid viscosity while the proposed VI can effectively and quantitatively identify the damping fluid viscosity.

A Review of Recent Advances in Superhydrophobic Surfaces and Their Applications in Drag Reduction and Heat Transfer

Inspired by the superhydrophobic properties of some plants and animals with special structures, such as self-cleaning, water repellent, and drag reduction, the research on the basic theory and practical applications of superhydrophobic surfaces is increasing. In this paper, the characteristics of superhydrophobic surfaces and the preparation methods of superhydrophobic surfaces are briefly reviewed. The mechanisms of drag reduction on superhydrophobic surfaces and the effects of parameters such as flow rate, fluid viscosity, wettability, and surface morphology on drag reduction are discussed, as well as the applications of superhydrophobic surfaces in boiling heat transfer and condensation heat transfer. Finally, the limitations of adapting superhydrophobic surfaces to industrial applications are discussed. The possibility of applying superhydrophobic surfaces to highly viscous fluids for heat transfer to reduce flow resistance and improve heat transfer efficiency is introduced as a topic for further research in the future.

Influence of proppant physical properties on sand accumulation in hydraulic fractures

The proppant accumulation form in fractures is related to the formation conductivity after fracture closure, also closely related to the production rate of oil/gas wells. In order to investigate the influence of proppant physical properties on sand accumulation in fractures, a particle–fluid coupling flow model is established based on the Euler two-fluid model. Geometric parameters of a fracture in tight oil wells are approximately scaled in equal proportion as the physical model, which is solved by the finite volume method. And the model accuracy is verified by comparing with the physical experimental simulation in the literature. Results show that the higher proppant concentration corresponds to the faster particle sedimentation rate, and the greater sand embankment accumulation as well. However, the fluid viscosity will increase, inhibiting proppant migration to the deep part of the fracture. Reducing proppant density and particle size will enhance the fluidization ability of particles, which is conducive to the migration to the deep fracture at the initial stage of pumping. But, it is not beneficial to have a desirable accumulation state in the middle and later pumping stage, so it is difficult to obtain a higher comprehensive equilibrium height.

Photorheological fluids of azobenzene polymers for lubrication regulation

Fluid viscosity is ubiquitous property and is of practical importance in intelligent fluids, industrial lubrication, and pipeline fluid transportation. Recently, there has been a surging interest in viscosity regulation. Here, we have developed a group of photorheological fluids by utilizing azobenzene polymers with a light-induced microstructure transformation. In this work, a photosensitive polymer with 4,4′-bis-hydroxyazobenzene as the main chain was designed and synthesized as a pivotal functional material. The sufficiently large structural difference under ultraviolet and near-infrared light makes it possible to regulate the viscosity of a polyethylene glycol solution. The viscosity of the photosensitive rheological fluids under ultraviolet light radiation is found to be up to 45.1% higher than that under near-infrared light radiation. To explore this intelligent lubricating technology, the friction regulation of ceramic sliding bearings was investigated utilizing photosensitive rheological fluids. Reversible friction regulation with a ratio of up to 3.77 has been achieved by the alternative irradiation of near-infrared and ultraviolet light, which can be attributed to the differences in mechanical properties and molecular structures under ultraviolet and near-infrared light according to both simulations and experiments. Such photorheological fluids will have promising applications in controllable lubrication, intelligent rheological fluids, and photosensitive dampers.