scholarly journals Multimorbidity and the health-related quality of life among people 50 years and up: results of a longitudinal study in New Zealand

2020 ◽  
Author(s):  
Nayyereh Aminisani ◽  
Chris Stephens ◽  
Fiona Alpass ◽  
Seyed Morteza Shamshirgaran
Keyword(s):  
Quality Of Life ◽  
Longitudinal Study ◽  
Population Based ◽  
Inverse Association ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Abstract Objective This study aimed to examine the association of Health-Related Quality of Life (HRQOL) and multimorbidity (MM) and its correlates over time in New Zealand.Methods People aged 55 years and over were invited to participate in a nationally representative population-based longitudinal study in 2006 and followed up biennially until 2016. GEE models, adjusted for both time-constant and time-varying factors used baseline and five subsequent waves of data, to compare a range of factors related to changes in MM and HRQOL.Results At baseline, 957 of the participants were classified as “MM participants”; 570 had two, and the rest had three chronic conditions. The results of the GEE modelling demonstrated that SF12-PCS decreased over time and there was a significant difference in SF12-PCS between MM and Non-MM participants. Having MM was negatively associated with HRQOL-PCS [-3.00 (95%CI -3.60, -2.49); p <0.001)]. Although the results showed an increase in SF12-MCS over time, the score of the mental dimension of HRQOL was lower among MM participants compared to Non-MM participants [-2.60, 95%CI -3.09, -2.11].Conclusions According to this longitudinal study, there is an inverse association between MM and one of the most important health outcomes; HRQOL, in older adults.

Multimorbidity and  health-related quality of life among people 55 years and up: results of a longitudinal study in New Zealand

2020 ◽  
Author(s):  
Nayyereh Aminisani ◽  
Chris Stephens ◽  
Fiona Alpass ◽  
Seyed Morteza Shamshirgaran
Keyword(s):  
Quality Of Life ◽  
Longitudinal Study ◽  
New Zealand ◽  
Inverse Association ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Abstract Background: This study aimed to examine the association of Health-Related Quality of Life (HRQOL) and multimorbidity (MM) and its correlates over time in New Zealand. Methods: People aged 55 years and over were invited to participate in a nationally representative population-based longitudinal study in 2006 and followed up biennially until 2016. Generalized Estimating Equations (GEE) with an exchangeable correlation matrix and robust standard errors adjusted for both time-constant and time-varying factors using baseline and five subsequent waves of data were used, to compare a range of factors related to changes in MM and HRQOL. Results: Of 2632 participants at baseline, 957 of the participants were classified as “MM participants”; 570 had two, and the rest had three chronic conditions. The results of the GEE regression models demonstrated that SF12-PCS decreased over time, and there was a significant difference in SF12-PCS between MM and Non-MM participants. Having MM was negatively associated with HRQOL-PCS [-3.00 (95 %CI -3.60, -2.49); p <0.001)]. Although the results showed an increase in SF12-MCS over time, the score of the mental dimension of HRQOL was lower among MM participants compared to Non-MM participants [-2.60, 95 %CI -3.09, -2.11]. Conclusions: According to this longitudinal study, there is an inverse association between MM and one of the most important health outcomes; HRQOL, in older adults.

Association of falls with health related quality of life (HRQOL) in older cancer patients: A population based longitudinal study.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e20524-e20524 ◽  
Author(s):  
Allison Magnuson ◽  
Chintan Pandya ◽  
William Dale ◽  
Lisa Lowenstein ◽  
Chunkit Fung ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Longitudinal Study ◽  
Cancer Patients ◽  
Population Based ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Older Cancer Patients

Health-Related Quality of Life Among 5-Year Survivors of Esophageal Cancer Surgery: A Prospective Population-Based Study

2012 ◽  
Vol 30 (4) ◽  
pp. 413-418 ◽  
Author(s):  
Maryam Derogar ◽  
Pernilla Lagergren
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Population Based ◽  
Health Related Quality ◽  
Background Population ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Over Time

Purpose To clarify whether health-related quality of life (HRQL) can be restored in 5-year survivors of esophageal cancer surgery. Patients and Methods The nationwide Swedish prospective and population-based cohort for this study consisted of patients with esophageal cancer who were treated surgically between 2001 and 2005 and were alive 5 years after surgery. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ-C30) and EORTC QLQ-OES18 (the disease site–specific module for esophageal cancer) were used to assess HRQL 6 months, 3 years, and 5 years postoperatively. Paired t tests were used to evaluate changes in HRQL over time. Patients' HRQL was classified as improved, stable, or deteriorated. Multivariable linear regression was used to calculate mean score difference in HRQL with 95% CIs between patients and a background population according to HRQL category. Results Among 153 eligible patients alive after 5 years, 117 (76%) answered all HRQL assessments. Among a random sample of 6,969 Swedish adults representing the corresponding background population, 4,910 (70.5%) participated. For most patients, HRQL remained stable or improved over time, and their HRQL was comparable to that of the background population. Patients who deteriorated over time reported large and clinically significant mean score differences for all measures. For example, 5 years after surgery, physical function was stable or improved in 86% of patients and their mean score (87) was similar to that of the background population (88), but the 14% who deteriorated had a substantially lower mean score of 56. Conclusion HRQL recovers to a level comparable to that in the background population in most patients who survive 5 years after esophagectomy for cancer, although a subgroup of patients has substantially worse HRQL.

scholarly journals P139 What impact does JIA have on health-related quality of life over time and by gender?

Rheumatology ◽  
2020 ◽  
Vol 59 (Supplement_2) ◽  
Author(s):  
Andrew Smith ◽  
Bishma Saqib ◽  
Rebecca Lee ◽  
Wendy Thomson ◽  
Lis Cordingley
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Child Health ◽  
Reference Population ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Over Time ◽  
Domain Scores

Abstract Background Juvenile idiopathic arthritis (JIA) is a heterogeneous group of arthritic conditions presenting in children and young people, in which physical limitations and associated complications can have detrimental effects on physical and psychosocial wellbeing. This study aims to investigate the impact of living with JIA on different aspects of health-related quality of life (HRQoL) and to explore how this changes over time, using data from the Childhood Arthritis Prospective Study (CAPS). Methods Longitudinal data collected as part of CAPS were analysed. HRQoL was assessed at baseline, 1 year and 3 years’ post-diagnosis using the Child Health Questionnaire (CHQ), a parent-completed form for children from 5 years of age. The CHQ measures physical, emotional and social components of child health status. Raw domain scores were transformed via algorithm into values ranging from 0-100, with higher scores indicating better health status. Mean (standard deviation) and median (interquartile range) for each domain were determined, both for the full cohort and by gender. Differences between median scores at baseline and 3 years were assessed using the Wilcoxon signed-rank test. Mean scores of each domain were visually compared with a reference population sample of healthy children from the United States. Results 184 participants completed the questionnaire at all 3 time points. At baseline, compared to the reference population, children with JIA scored lower in every domain although scores were closer between the 2 groups at 3 years. Median scores improved over time, the exception being the general health perceptions domain which decreased after baseline. Domains with the greatest improvement were physical functioning,“bodily pain and social-physical. The largest changes occurred from baseline to 1 year. Statistically significant differences between baseline and 3-year scores were found for all domains. Domain scores for male and female participants were very similar at baseline, though scores for male participants indicated slightly better health at 1 and 3 years for both physical and psychosocial domains. Conclusion JIA has significant impact on HRQoL, which improves within 3 years of diagnosis with the greatest improvement occurring within the first year. Physical health domains show greater improvement over time than psychosocial domains, although psychosocial scores were generally higher throughout the study. Male participants tend to score slightly higher than female participants in both physical and psychosocial domains after baseline. Further research should explore measurable patient, age or disease-related drivers of HRQoL. Disclosures A. Smith None. B. Saqib None. R. Lee None. W. Thomson None. L. Cordingley None.

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