scholarly journals Human Immunodeficiency Virus Positive status disclosure to a sexual partner and its determinant factors in Ethiopia. A systematic review and meta-analysis.

2020 ◽  
Author(s):  
Fikadu Ambaw Yehualashet ◽  
Eleni Tesfaye Tegegne ◽  
Mekbib Kassa Tessema ◽  
Mulualem Endeshaw
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Pooled Prevalence ◽  
Immunodeficiency Virus ◽  
Regression Test ◽  
Status Disclosure ◽  
Hiv Aids

Abstract Background: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to raise awareness and to reduce risky behaviors. Hence, this study aimed to determine the pooled prevalence and effect sizes of determinant factors of HIV positive status disclosure through a systematic review and meta-analysis of the results of the existing primary studies in Ethiopia. Method: This systematic review and meta-analysis was aimed to determine prevalence of HIV positive status disclosure and associated factors by considering and searching published primary articles from different sources. A sensitivity test was conducted to evaluate the presence of influential studies. Besides, the heterogeneity test has been conducted; and publication bias was examined through observing the funnel plot as well as objectively by interpreting the Egger’s regression test. Following the Egger’s regression test, P-value <0.05 was considered as statistically significant at 95% Confidence Interval. Result: A total of 18 primary studies were searched from different data sources. The overall pooled prevalence of HIV positive status disclosure among adult PLWHA in Ethiopia was indicated to be 75.95% (95% CI:69.93-81.98); the highest and lowest pooled estimated HIV status disclosure was in Amhara (82.78%) and Tigray (54.31%) regions respectively. Furthermore, Knowing the HIV positive status of sexual partner, AOR=19.66(95% CI: 10.19-37.91), having prior discussion about HIV testing with their partner, AOR=9.18(95% CI: 5.53-15.24), got Human Immunodeficiency Virus pretest counseling service AOR=4.29(95% CI: 2.56-7.21) and being a member of HIV/AIDS associations, AOR=3.34(95% CI: 2.17-5.12), were significantly associated with HIV positive status disclosure among People living With HIV/AIDS in Ethiopia.Conclusion: The pooled national estimate of HIV/AIDS positive status disclosure is low as compared to the WHO disclosure rate of developing countries and the findings of other national and international studies. Ministry of health and other stakeholders shall design new approaches and strategies to encourage disclosure of HIV status, educate the public about the negative impact of nondisclosure within family members. Health care providers working at Human HIV test centers shall emphasis extensive counseling on disclosure of status to a partner. Moreover, different stakeholders, health workers and community members shall establish, organize, and support HIV/AIDS Associations and motivate HIV positive people to be engaged and participated.

Human Immunodeficiency Virus Positive status disclosure to a sexual partner and its determinant factors in Ethiopia. A systematic review and meta-analysis.

2020 ◽  
Author(s):  
Fikadu Ambaw Yehualashet ◽  
Eleni Tesfaye Tegegne ◽  
Mekbib Kassa Tessema ◽  
Mulualem Endeshaw
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Pooled Prevalence ◽  
Immunodeficiency Virus ◽  
Regression Test ◽  
Status Disclosure ◽  
Hiv Aids

Abstract Background: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to raise awareness and to reduce risky behaviors. Hence, this study aimed to determine the pooled prevalence and effect sizes of determinant factors of HIV positive status disclosure through a systematic review and meta-analysis of the results of the existing primary studies in Ethiopia. Method: This systematic review and meta-analysis was aimed to determine prevalence of HIV positive status disclosure and associated factors by considering and searching published primary articles from different sources. A sensitivity test was conducted to evaluate the presence of influential studies. Besides, the heterogeneity test has been conducted; and publication bias was examined through observing the funnel plot as well as objectively by interpreting the Egger’s regression test. Following the Egger’s regression test, P-value <0.05 was considered as statistically significant at 95% Confidence Interval. Result: A total of 18 primary studies were searched from different data sources. The overall pooled prevalence of HIV positive status disclosure among adult PLWHA in Ethiopia was indicated to be 75.95% (95% CI:69.93-81.98); the highest and lowest pooled estimated HIV status disclosure was in Amhara (82.78%) and Tigray (54.31%) regions respectively. Furthermore, Knowing the HIV positive status of sexual partner, AOR=19.66(95% CI: 10.19-37.91), having prior discussion about HIV testing with their partner, AOR=9.18(95% CI: 5.53-15.24), got Human Immunodeficiency Virus pretest counseling service AOR=4.29(95% CI: 2.56-7.21) and being a member of HIV/AIDS associations, AOR=3.34(95% CI: 2.17-5.12), were significantly associated with HIV positive status disclosure among People living With HIV/AIDS in Ethiopia.Conclusion: The pooled national estimate of HIV/AIDS positive status disclosure is low as compared to the WHO disclosure rate of developing countries and the findings of other national and international studies. Ministry of health and other stakeholders shall design new approaches and strategies to encourage disclosure of HIV status, educate the public about the negative impact of nondisclosure within family members. Health care providers working at Human HIV test centers shall emphasis extensive counseling on disclosure of status to a partner. Moreover, different stakeholders, health workers and community members shall establish, organize, and support HIV/AIDS Associations and motivate HIV positive people to be engaged and participated.

scholarly journals Sero-positive HIV result disclosure to sexual partner in Ethiopia: a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Fantahun Ayenew Mekonnen ◽  
Ayenew Molla Lakew ◽  
Kindie Fentahun Muchie ◽  
Destaw Fetene Teshome
Keyword(s):  
Systematic Review ◽  
Positive Result ◽  
Sexual Partner ◽  
Meta Analysis ◽  
Outcome Variable ◽  
Hiv Positive ◽  
Hiv Status ◽  
Previous Discussion ◽  
Hiv Status Disclosure ◽  
Status Disclosure

Abstract Background The infection of HIV continues to be an important public health problem in Ethiopia. Disclosing own HIV positive result is crucial, and considered as a good indicator of behavior change towards HIV/AIDs. A systematic review and meta-analysis was conducted to pool the prevalence of positive HIV status disclosure to sexual partners and determine the influence of selected factors. Methods This systematic review and meta-analysis was conducted in Ethiopia among HIV positive people receiving health care at health facilities. In this review, primary studies were searched in Medline via PubMed, Google scholar and Google up to November, 2018. Data on disclosure of HIV positive result, knowledge of partner’s HIV status and prior discussion on HIV were extracted, and effect sizes like proportion and odds ratios were pooled. Heterogeneity and publication bias were assessed by chi-square and I2, and Egger test, respectively. Results A total of 12 studies with 4528 participants were included in to this review to estimate the prevalence of disclosure of HIV positive result to sexual partner, and 10 and 7 studies were included to determine the associations of the outcome variable with knowledge of sexual partner’s HIV status and with prior discussion on HIV, respectively. The pooled prevalence of HIV status disclosure to sexual partner was 73% (95% CI: 64, 82%). Having the knowledge of sexual partner’s HIV status [OR: 95%CI; 17.63 (7.88, 39.45)], and previous discussion on HIV [OR: 95% CI; 9.24 (5.56, 15.37)] increased the disclosure of own HIV positive result to sexual partner. The sub-group analysis indicated a prevalence of 74% in Oromia, 86% in Southern Nations Nationalities and Peoples (SNNPR), 87% in Amhara, 73% in Addis Ababa, and 54% in Tigray. Conclusions Disclosure of HIV status to sexual partner is lower than expected. Knowledge of partner’s HIV status and previous discussion on HIV were strong predictors of HIV positive status disclosure. Strategies helpful for encouraging open HIV discussion need to be strengthened to increase HIV positive result disclosure. Furthermore, since the heterogeneity of studies is high, large nationally representative study is suggested.

HIV-Tuberculous Meningitis Co-infection: A Systematic Review and Meta-analysis

2020 ◽  
Vol 21 ◽  
Author(s):  
Ali Purmohamad ◽  
Taher Azimi ◽  
Mohammad Javad Nasiri ◽  
Mehdi Goudarzi ◽  
Moein Zangiabadian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Tuberculous Meningitis ◽  
Preventive Measures ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Analysis Model ◽  
Pooled Prevalence ◽  
Immunodeficiency Virus ◽  
High Prevalence

: Human immunodeficiency virus (HIV)-infected persons are at a higher risk of developing Tuberculous meningitis (TBM). We aimed to estimate the prevalence of TBM-HIV co-infection. We systematically searched Pubmed/Medline, Embase and Cochrane library databases from January 1, 2000, to January 31, 2017, to find relevant studies. We employed the random-effects meta-analysis model to estimate the pooled prevalence of TBM-HIV co-infection. Twenty-six eligible studies showed the prevalence of HIV in TBM patients. In the pooled analyses, the prevalence of HIV was 30% (95% CI: 12-47) in patients with confirmed TBM, and 12.1% (95% CI: 7.3-19.2) in patients with suspected TBM. This study shows a high prevalence of TBM-HIV co-infection. Establishing proper diagnostic criteria and preventive measures for TBM infections could assist in the prevention and management of TBM infection, particularly TBM-HIV co-infection.

scholarly journals Dual contraceptive utilization and determinant factors among HIV positive women in Ethiopia: a systematic review and meta-analysis, 2020

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Alemu Degu Ayele ◽  
Bekalu Getnet Kassa ◽  
Fentahun Yenealem Beyene ◽  
Dagne Addisu Sewyew ◽  
Gedefaye Nibret Mihretie
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Hiv Positive Women ◽  
Pooled Prevalence ◽  
Post Test ◽  
Contraceptive Utilization ◽  
Open Discussion ◽  
Partner Involvement

Abstract Background Dual contraceptive is the use of a barrier like condom along with any modern contraceptive methods which has double significance for the prevention STI including HIV and unintended pregnancy. The prevalence and determinants of dual contraceptive utilization described by different studies were highly inconsistent in Ethiopia. Therefore, this systematic review and meta-analysis aimed to estimate the pooled prevalence and determinants of dual contraceptive utilization among HIV positive women in Ethiopia. Methods International database mainly Pub Med, Google scholar, HINARI, EMBASE, Cochrane Library, AJOL was applied to identify original studies. STATA software version 14 was applied to analyze the pooled prevalence of dual contraceptive. I2 test statistics was computed to check the presence of heterogeneity across the studies and eggers test was used to identify publication bias. The pooled prevalence of dual contraceptive utilization was estimated by using a random effects model. The associations between determinants and dual contraceptive utilization were evaluated by using both random and fixed effect models. Result A total 9 studies with 9168 HIV positive women were enrolled in this study. The pooled prevalence of dual contraceptive utilization among HIV positive women in Ethiopia was 26.14% (95% CI 21.20–31.08). Disclosure of HIV status (OR = 4.18,95%CI:2.26–7.72), partner involvement in post-test counselling (OR = 2.31,95%CI:1.63–3.25), open discussion about dual contraceptive with partner (OR = 4.27 95% CI:1.69–10.77), provision of counselling on dual contraceptives by health care provider (OR = 4.47,95% CI:3.81–5.24) and CD4 count > 350 cells/ mm3 (OR = 3.87,95%CI:3.53–4.23) were among the significant factors associated with dual contraceptive utilization. Conclusion The overall prevalence of dual contraceptive utilization among HIV positive women was significantly low. Disclosure of HIV status, partner involvement in post-test counselling, open discussion about dual contraceptive with partner, counselling on dual contraceptive by health care provider and CD4 count > 350 cells/ mm3 were positively affect dual contraceptive utilization. This study implies the need to develop plans and policies to improve partner involvement posttest counseling, integrate the counseling and provision of dual contraceptive at ART clinic at each level of health system.

Food insecurity and its gender disparity among adult people living with Human Immunodeficiency Virus in Ethiopia: A systematic review and meta-analysis

2019 ◽  
Author(s):  
Dube Jara Boneya ◽  
Ahmed Ali Ahmed ◽  
Alemayehu Worku Yalew
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Food Insecurity ◽  
Meta Analysis ◽  
Gender Disparity ◽  
Cochrane Library ◽  
Pooled Prevalence ◽  
Immunodeficiency Virus ◽  
Living With Hiv

Abstract Background People living with Human Immunodeficiency Virus may lack access to sufficient quantities of nutritious foods and are vulnerable to food insecurity. Studies suggest there is gender-based inequality in the experience of food insecurity. The few studies conducted on the prevalence of food insecurity among adults living with Human Immunodeficiency Virus in Ethiopia presented inconclusive findings. Therefore, the objective of the current systematic review and meta-analysis was to estimate the pooled prevalence of food insecurity and its gender disparity among adult patients living with HIV and receiving antiretroviral therapy in Ethiopia.Method We followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The research databases PubMed, Google Scholar, CINAHL, PopLine, MedNar, Embase, Cochrane library, the JBI Library and the WEB OF SCIENCE were searched using keywords. We included studies reporting prevalence of food insecurity among adults aged greater than 18 years who were living with HIV and receiving antiretroviral therapy. The meta-analysis was conducted using STATA 14 software. A random effects model was used to estimate the pooled prevalence at 95% CI. Funnel plots and Egger’s and Begg’s tests were used to check for publication bias.Results A total of 52 studies representing 4031 adults were identified; eleven studies were included in the meta-analysis. The overall pooled estimated prevalence of food insecurity was 63.44% (95% CI: 46.33-80.54%). A higher pooled prevalence of food insecurity was observed among females (68.85%, 95% CI (57.88%, 79.81%)) compared to males (31.15%, 95% CI (20.19%, 42.12%)).Conclusion The review demonstrates a high prevalence of food insecurity among people living with HIV in Ethiopia, with evidence of greater vulnerability among women. Interventions should be culture and context specific to address regional and gender disparities in the prevalence of food insecurity.

scholarly journals Human Immunodeficiency Virus Status in Malnourished Children seen at Lagos

2018 ◽  
Author(s):  
EO Temiye ◽  
OF Adeniyi ◽  
IB Fajolu ◽  
AA Ogbenna ◽  
TA Ladapo ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Total Protein ◽  
Protein Energy Malnutrition ◽  
World Health ◽  
Full Blood Count ◽  
Hiv Positive ◽  
Hiv Status ◽  
Malnourished Children ◽  
Immunodeficiency Virus ◽  
Oral Thrush

AbstractIntroductionHuman immunodeficiency virus and protein energy malnutrition are still prevalent in Nigeria and the occurrence of the two conditions together confers a poor prognosis. The aim of this study was to determine the current categories of malnutrition amongst under 5 children in Lagos, document their HIV status and determine any peculiarities in the clinical features, haematological and some biochemical profile in these children.MethodsThe study was a prospective crossectional study conducted at the Paediatric department of the Lagos University Teaching Hospital and the Massey Street Children’s Hospital over a 6 month period. All the subjects had anthropometry, HIV testing, full blood count and serum proteins done. The factors associated with HIV status were determined with the logistic regression analysis.ResultsTwo hundred and fourteen (214) malnourished children ≤5 years were recruited into the study and 25(11.7%) were HIV positive. One hundred and five (49.1%) of the participants had moderate malnutrition while 25.2% had severe forms of malnutrition. Fever, cough and diarrhea were the commonest symptoms. Severe wasting, oral thrush, dermatoses and splenomegaly were seen more commonly in the HIV positive subjects. The haematological indices were comparable in the two groups, however, the total protein was significantly higher in the HIV positive subjects compared to the negative group (p=0.042). Multivariate analysis showed that the total protein (p=0.001) and platelet count (p=0.016) could significantly predict the occurrence of HIV in the malnourished childrenConclusionThe presence of severe wasting, oral thrush, diarrhea, splenomegaly, thrombocytopenia and high total proteins in malnourished children should heighten the suspicion of possible underlying associated HIV infection. This study reinforces the recommendation by the World Health Organisation (WHO) that all malnourished children should have mandatory HIV screening.

scholarly journals THE THORNY ISSUE OF STATUS DISCLOSURE TO CHILDREN LIVING WITH HIV: THE CASE OF HIV POSITIVE CHILDREN LIVING IN A CHILD AND YOUTH CARE FACILITY IN JOHANNESBURG, SOUTH AFRICA

2016 ◽  
Vol 28 (1) ◽  
pp. 53-68
Author(s):  
Nkosiyazi Dube ◽  
Linda Harms Smith
Keyword(s):  
South Africa ◽  
Social Service ◽  
Youth Care ◽  
Hiv Positive ◽  
Hiv Status ◽  
Service Workers ◽  
Child And Youth Care ◽  
Living With Hiv ◽  
Status Disclosure ◽  
Hiv Aids

There is a dilemma regarding HIV/AIDS disclosure to children born and living with HIV/AIDS in residential settings. Since the advent and accessibility of Anti-Retroviral Therapy, most children born HIV positive live longer and have healthier lives. Some of these children find themselves in Need of Care due to abandonment, orphanhood and neglect or abuse, and are placed in alternative care such as a Child and Youth Care Centre (CYCC). Social Service Workers are then faced with this dilemma around disclosure of their HIV status, due to the complexities around the consequences of such a disclosure, and the absence of clear policies in this regard. The study explored the perceptions of social service workers regarding disclosure of HIV status to children born HIV positive living in a CYCC in Ekurhuleni, South Africa. The findings indicate that HIV status disclosure is a complex but essential process as it reinforces children’s ability to adhere to medication and dispels anxiety and suspicion within themselves around their status. Recommendations relate to community education and awareness programmes, policy and practice changes and makes suggestions for future research.

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