scholarly journals Improving oral hygiene may attenuate occurrence of head and neck cancer: nation-wide population based cohort study.

2020 ◽  
Author(s):  
Ho Geol Woo ◽  
Kijeong Lee ◽  
Ji Sung Lee ◽  
Jinkwon Kim ◽  
Younkyung Chang ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Oral Health ◽  
Periodontal Disease ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Hygiene ◽  
Tooth Loss ◽  
Population Based ◽  
Tooth Brushing ◽  
Laboratory Findings

Abstract Background: In previous case-control and cross-sectional studies, less frequent dental visits, infrequent tooth brushing, presence of periodontal disease, and increased number of tooth loss were shown to be associated with increased risk of head and neck cancer. However, studies regarding the association of periodontal disease and parameters of oral health with occurrence of head and neck cancer have been lacking particularly in longitudinal setting. We aimed to investigate the relationship between parameters of oral health and risk of head and neck cancer in a nationwide general population-based cohort.Methods : We included 150,774 subjects from the Korean National Health Insurance System-Health Screening Cohort for demographics, past history, and laboratory findings. The presence of periodontal disease and parameters of oral health including frequency of tooth brushings, dental visit for any reason, expertised dental cleaning, and number of tooth loss were investigated. Head and neck cancer was defined as International Statistical Classification of Diseases-10 codes of ‘C00-C14’.Results: During median 11.1 years of follow-up, 1,155 (0.76%) head and neck cancers occurred. Based on multivariable analysis, after adjusting for demographics, alcohol intake, smoking, regular exercise, body mass index, systolic blood pressure, blood and urinary laboratory findings, and parameters of oral health, frequent tooth brushing (more than three times per day) was related to lower risk of head and neck cancer (hazard ratio, HR: 0.78, 95% confidence interval, CI: 0.66–0.93, p=0.005). Increased number of tooth loss was positively associated with occurrence of head and neck cancer (p value for trend test for HR <0.001).Conclusions : The occurrence of head and neck cancer was decreased with the more frequent tooth brushing (more than three times per day) and increased with the number of tooth loss. In regards of head and neck cancer prevention, improving oral hygiene may have significant contribution.

scholarly journals Infrequent tooth brushing and teeth lost may increase the risk of oral and pharyngeal cancers: A nationwide population-based cohort study in Korea.

2020 ◽  
Author(s):  
Ho Geol Woo ◽  
Kijeong Lee ◽  
Ji Sung Lee ◽  
Jinkwon Kim ◽  
Younkyung Chang ◽  
...  
Keyword(s):  
Oral Health ◽  
Alcohol Consumption ◽  
Oral Hygiene ◽  
Population Based ◽  
Tooth Brushing ◽  
Poor Oral Hygiene ◽  
National Health Insurance System ◽  
Laboratory Findings ◽  
Number Of Teeth ◽  
Study Results

Abstract Background: Oral and pharyngeal cancers are emerging and troublesome diseases worldwide. Although poor oral hygiene behaviors and parameters affecting oral health have been considered as potential risk factors of oral and pharyngeal cancers including smoking and alcohol consumption for decades, study results have been inconsistent. Longitudinal studies regarding the association between poor oral hygiene behaviors and parameters of oral health and the occurrence of oral and pharyngeal cancers have been lacking. We aimed to investigate this relationship in a nationwide general population-based cohort.Methods: We included data on demographics, past history, and laboratory findings for 150,774 subjects without teeth lost from the Korean National Health Insurance System-Health Screening Cohort. The presence of periodontal disease and parameters of oral health, including frequency of tooth brushings, dental visits for any reason, professional teeth scaling, and number of teeth lost, were investigated. Oral and pharyngeal cancers were defined by the International Statistical Classification of Diseases, 10th Revision, codes of C00-C14.Results: During a median 11.1 years of follow-up, 1,155 (0.77%) oral and pharyngeal cancers occurred. Based on multivariable analysis, after adjusting for demographics, alcohol consumption, smoking status, regular exercise, body mass index, systolic blood pressure, blood and urinary laboratory findings, and parameters of oral health including frequent tooth brushing (three or more times per day) were related to a lower risk of oral and pharyngeal cancers (hazard ratio [HR]: 0.78, 95% confidence interval [CI]: 0.66–0.93, p=0.005). An increased number of teeth lost (≥15) was positively associated with occurrence of oral and pharyngeal cancers (HR: 1.71, 95% CI: 1.26–2.31, p=0.001 in model 1; HR: 1.68, 95% CI: 1.24–2.28, p<0.001 in model 2; HR: 1.66, 95% CI: 1.22–2.25, p=0.001 in model 3; p-value for trend test for HR <0.001).Conclusions: The occurrence of oral and pharyngeal cancers decreased with more frequent tooth brushing (three or more times per day) and increased with the number of teeth lost. With regards to the prevention of oral and pharyngeal cancers, improving oral hygiene may have a significant contribution.

scholarly journals Incidence of Oral Mucositis in Patients Undergoing Head and Neck Cancer Treatment: Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Negative Impact ◽  
Meta Analysis ◽  
Incidence Rates

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.

scholarly journals Fewer head and neck cancer diagnoses and faster treatment initiation during COVID-19 in 2020: a nationwide population-based analysis

2021 ◽  
Author(s):  
Rosanne C. Schoonbeek ◽  
Dominique V.C. de Jel ◽  
Boukje A.C. van Dijk ◽  
Stefan M. Willems ◽  
Elisabeth Bloemena ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Treatment Initiation ◽  
Population Based

scholarly journals Benefit from surgery with additional radiotherapy in N1 head and neck cancer at the time of IMRT: A population-based study on recent developments

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0229266 ◽  
Author(s):  
Christoph Evers ◽  
Christian Ostheimer ◽  
Frank Sieker ◽  
Dirk Vordermark ◽  
Daniel Medenwald
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Population Based ◽  
Population Based Study ◽  
Recent Developments

scholarly journals Disease trajectories, place and mode of death in people with head and neck cancer: Findings from the ‘Head and Neck 5000’ population-based prospective clinical cohort study

2020 ◽  
Vol 34 (5) ◽  
pp. 639-650 ◽  
Author(s):  
Catriona R Mayland ◽  
Kate Ingarfield ◽  
Simon N Rogers ◽  
Paola Dey ◽  
Steven Thomas ◽  
...  
Keyword(s):  
Palliative Care ◽  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Population Based ◽  
Hospital Death ◽  
Care Needs ◽  
Curative Intent ◽  
Mode Of Death

Background: Few large studies describe initial disease trajectories and subsequent mortality in people with head and neck cancer. This is a necessary first step to identify the need for palliative care and associated services. Aim: To analyse data from the Head and Neck 5000 study to present mortality, place and mode of death within 12 months of diagnosis. Design: Prospective cohort study. Participants: In total, 5402 people with a new diagnosis of head and neck cancer were recruited from 76 cancer centres in the United Kingdom between April 2011 and December 2014. Results: Initially, 161/5402 (3%) and 5241/5402 (97%) of participants were treated with ‘non-curative’ and ‘curative’ intent, respectively. Within 12 months, 109/161 (68%) in the ‘non-curative’ group died compared with 482/5241 (9%) in the ‘curative’ group. Catastrophic bleed was the terminal event for 10.4% and 9.8% of people in ‘non-curative’ and ‘curative’ groups, respectively; terminal airway obstruction was recorded for 7.5% and 6.3% of people in the same corresponding groups. Similar proportions of people in both groups died in a hospice (22.9% ‘non-curative’; 23.5% ‘curative’) and 45.7% of the ‘curative’ group died in hospital. Conclusion: In addition to those with incurable head and neck cancer, there is a small but significant ‘curative’ subgroup of people who may have palliative needs shortly following diagnosis. Given the high mortality, risk of acute catastrophic event and frequent hospital death, clarifying the level and timing of palliative care services engagement would help provide assurance as to whether palliative care needs are being met.

Chronic rhinosinusitis after radiotherapy in patients with head and neck cancer: a population‐based cohort study in Taiwan

2020 ◽  
Vol 10 (5) ◽  
pp. 692-697
Author(s):  
Yen‐Ting Lu ◽  
Ying‐Chou Lu ◽  
Hui‐Chen Cheng ◽  
Chung‐Han Hsin ◽  
Shun‐Fa Yang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Chronic Rhinosinusitis ◽  
Neck Cancer ◽  
Population Based
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