Analysis of the Spontaneous Conception Outcome in Infertile Women After Four-dimensional Hysterosalpingo-Contrast-Sonography
Abstract Background: to evaluate the correlation between spontaneous conception outcome and the patients’ clinical characteristics as well as tubal patency in infertile women after four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy).Methods:Two hundred and eighty three infertile patients performed 4D-HyCoSy between December 2014 and October 2017,based on a normal semen analysis according to World Health Organization criteria, spontaneous conception without clinical interventions after 4D-HyCoSy, were trying to become conception. We analyzed the relationship between spontaneous conception outcome and clinical characteristics and tubal patency of infertile women after 4D-HyCoSy.Result(s): One hundred and sixteen patients (40.9%) conceived spontaneously and the mean conception time was (8.8 ± 0.3) months. With Cox regression analysis, two factors associated with spontaneous conception outcome appeared to increase spontaneous conception rate: patients with type IV or type VI tubes and duration of infertility less than 2 years.The age, type of infertility, multiparas, history of pelvic surgery, history of uterine cavity operation, uterine fibromyomata and polycystic ovary were unrelated to spontaneous conception outcome after 4D-HyCoSy.Conclusion(s):This study showed that some infertile women could succeed in spontaneous conception after 4D-HyCoSy. Hence, infertile patients should be advised to accept 4D-HyCoSy examination as soon as possible and based on the 4D-HyCoSy they could chose the appropriate clinical intervention. According to the results, expectant treatment of about 8-9 months is reported to be feasible for infertile women whose 4D-HyCoSy findings showed one tube patency or poor patency, especially for those with bilateral tubes patency or bilateral tubes poor patency.Alternatively, an immediate clinical intervention is recommended for those with bilateralobstructed tubes.