scholarly journals Glomus Tumor of Small Intestine: Case Report and Review of Literature

2021 ◽  
Author(s):  
Yan Tan ◽  
Xinyi Wang ◽  
Guifang Yang ◽  
Lan Liu ◽  
Jun Fang ◽  
...  
Keyword(s):  
Small Intestine ◽  
Glomus Tumor ◽  
Final Diagnosis ◽  
Good Prognosis ◽  
Proliferation Index ◽  
Ki 67 ◽  
Glomus Tumors ◽  
Pathologic Features ◽  
Single Balloon ◽  
Single Balloon Enteroscopy

Abstract Background: Glomus tumors are exceedingly rare tumors arising from the normal glomus body. Only a very few cases of glomus tumors located in the small intestine were reported to date. Here, we present a case of glomus tumor of the jejunum in a 30-year-old female patient, and discuss its clinical, imaging, and pathologic features.Case presentation: A 30-year-old female referred to our hospital with the chief complain of melena and fatigue for 3 weeks. Oral single-balloon enteroscopy discovered a 2.0*2.0cm tumor without epithelial lining in the jejunum. The patient then underwent partial enterectomy. HE stain illustrated that the tumor was interspersed with congestive capillaries of various size, and admixed with smooth muscle bundles. Immunohistochemical study showed that the tumor cells were strongly positive for SMA and collagen type Ⅳ. The Ki-67 proliferation index was less than 1% and mitotic activity is very low (about 1/50 HPF). The case was finally diagnosed as benign glomus tumor. Conclusion: Glomus tumors arising from the small intestine are extremely rare. The final diagnosis is made by histological and immunohistochemical examination. Although there is no standardized management pathway for these patients, early diagnosis and treatment are important for a good prognosis.

scholarly journals Glomus tumor of small intestine: case report and review of literature

2021 ◽  
Author(s):  
Yan Tan ◽  
Xinyi Wang ◽  
Guifang Yang ◽  
Lan Liu ◽  
Jun Fang ◽  
...  
Keyword(s):  
Small Intestine ◽  
Glomus Tumor ◽  
Final Diagnosis ◽  
Good Prognosis ◽  
Proliferation Index ◽  
Review Of Literature ◽  
Ki 67 ◽  
Glomus Tumors ◽  
Single Balloon ◽  
Single Balloon Enteroscopy

Abstract BackgroundGlomus tumors are exceedingly rare tumors arising from the normal glomus body. Only a very few cases of glomus tumors located in the small intestine were reported to date. Here, we present a case of glomus tumor of the jejunum in a 30-year-old female patient, and discuss its clinical, imaging, and pathologic features.Case presentationA 30-year-old female referred to our hospital with the chief complain of melena and fatigue for 3 weeks. Oral single-balloon enteroscopy discovered a 2.0*2.0cm tumor without epithelial lining in the jejunum. The patient then underwent partial enterectomy. HE stain illustrated that the tumor was interspersed with congestive capillaries of various size, and admixed with smooth muscle bundles. Immunohistochemical study showed that the tumor cells were strongly positive for SMA and collagen type Ⅳ. The Ki-67 proliferation index was less than 1% and mitotic activity is very low (about 1/50 HPF). The case was finally diagnosed as benign glomus tumor.ConclusionsGlomus tumors arising from the small intestine are extremely rare. The final diagnosis is made by histological and immunohistochemical examination. Although there is no standardized management pathway for these patients, early diagnosis and treatment are important for a good prognosis.

scholarly journals Glomus tumor of small intestine: case report and review of literature

2021 ◽  
Author(s):  
Yan Tan ◽  
Xinyi Wang ◽  
Guifang Yang ◽  
Lan Liu ◽  
Jun Fang ◽  
...  
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Female Patient ◽  
Glomus Tumor ◽  
Review Of Literature ◽  
Clinical Imaging ◽  
Glomus Tumors ◽  
Rare Tumors ◽  
Pathologic Features ◽  
Glomus Body

Abstract Glomus tumors are exceedingly rare tumors arising from the normal glomus body. Only a very few cases located in the small intestine were reported to date. Here, we present a case of glomus tumor of the jejunum in a 30-year-old female patient, and discuss its clinical, imaging, and pathologic features.

scholarly journals Haemorrhagic ileal haemolymphangioma: a case report and review of the literature

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098667
Author(s):  
Shou-Xing Yang ◽  
Yu-Hui Zhou ◽  
Jing Zhang ◽  
Lei Miao ◽  
Jing-Wei Zhong ◽  
...  
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Final Diagnosis ◽  
Review Of The Literature ◽  
History Of ◽  
Single Balloon ◽  
Single Balloon Enteroscopy ◽  
Rare Benign Tumour ◽  
Laparoscopic Assisted ◽  
Treitz Ligament

We describe herein a 37-year-old woman with a 2-week history of melena who was eventually diagnosed with ileal haemolymphangioma, a rare benign tumour. Local mucosal congestion and swelling were found through single-balloon enteroscopy, which showed an irregular protuberance approximately 10 cm long, located 3.2 m from the Treitz ligament. We performed a laparoscopic-assisted partial resection of the small intestine combined with intestinal adhesiolysis. According to postoperative pathology, the final diagnosis was ileal haemolymphangioma with haemorrhage.

scholarly journals Mandibular odontogenic sarcoma (ameloblastic fibrodentinosarcoma) in an aged cat — Short communication

2017 ◽  
Vol 65 (1) ◽  
pp. 89-95
Author(s):  
Gustavo A. Ramírez ◽  
Lorenzo Ressel ◽  
Jaume Altimira ◽  
Miquel Vilafranca
Keyword(s):  
Alveolar Bone ◽  
S100 Protein ◽  
Final Diagnosis ◽  
Proliferation Index ◽  
Cell Component ◽  
Ki 67 ◽  
Histologic Subtype ◽  
Odontogenic Tumours ◽  
Odontogenic Epithelium ◽  
Shaped Cell

A 13-year-old male cat presented with an ill-defined mass in the rostral mandible causing destruction and loss of alveolar bone. Microscopically, the mass consisted of cords or islands of benign odontogenic epithelium and a malignant, pleomorphic spindle-shaped cell component with dysplastic dentine formation. Immunohistochemically, neoplastic mesenchymal cells proved to be strongly positive for vimentin and negative for cytokeratins, desmin, actin and S100 protein; the Ki67 proliferation index was high. Morphological and immunohistochemical features largely overlap those reported for ameloblastic fibrodentinosarcoma, an uncommon histologic subtype of odontogenic sarcoma recognised in humans but no reported previously in animals. Ki-67 expression assessment may help to discriminate between malignant and benign forms of odontogenic tumours but the final diagnosis is mainly morphological.

scholarly journals Neurendocrine tumor of common hepatic duct: an uncommon site tumor

2019 ◽  
Vol 9 (2) ◽  
pp. 1599-1603
Author(s):  
Pallavi Srivastava ◽  
Saumya Shukla ◽  
Nuzhat Husain ◽  
Priyanka Sameer
Keyword(s):  
Neuroendocrine Tumor ◽  
Epigastric Pain ◽  
Hepatic Duct ◽  
Tumor Resection ◽  
Final Diagnosis ◽  
Proliferation Index ◽  
Common Hepatic Duct ◽  
Intravenous Chemotherapy ◽  
Ki 67 ◽  
Histopathology Examination

The neuroendocrine tumor of extrahepatic biliary tract is a rare neoplasm of the gastrointestinal tract. We present a case of 16 year old male presenting with epigastric pain and jaundice with a well-defined lesion in common hepatic duct on imaging. The patient underwent tumor resection. Histopathology examination revealed thickened common hepatic duct infiltrated by tumor cells with expression of Pan CK, Synaptophysin & Chromogranin with Ki- 67 proliferation index of 5%. The final diagnosis of Neuroendocrine tumor of Common Hepatic Duct, grade 2 was rendered. The patient showed no recurrence to date without intravenous chemotherapy.

HIGH-TECH DIAGNOSTIC METHODS AND AN ENTEROSCOPIC TREATMENT OF CHILDREN WITH PEUTZ-JEGHERS SYNDROME

2019 ◽  
Vol 22 (1) ◽  
pp. 17-22
Author(s):  
E. V. Kirakosyan ◽  
M. M. Lokhmatov ◽  
E. Yu. Dyakonova
Keyword(s):  
Small Intestine ◽  
Postoperative Period ◽  
Bowel Perforation ◽  
Diagnostic Methods ◽  
High Tech ◽  
Surgical Removal ◽  
Balloon Enteroscopy ◽  
Peutz Jeghers Syndrome ◽  
Single Balloon ◽  
Single Balloon Enteroscopy

Peutz-Jeghers syndrome (PJS) is an autosomal dominant hereditary hamartomatous polyposis with predominant localization in the jejunum and ileum. Because of PJS polyps differ from adenomatous ones, the performing polypectomy is associated with a high risk of bowel perforation. During 2015-2017 18 PJS children were comprehensively examined including esophagogastroduodenoscopy, colonoscopy, and video capsule endoscopy There was developed a step-by-step procedure for the removal of polyps common in all parts of the small intestine, including the creation of a “persistent pillow”; electroexcision of a polyp and application of a clip to the region of the womb of a removed polyp. Polyps more than 7 mm detected in the stomach and duodenum, were removed during endogastroduodenoscopy, and in the colon - under a colonoscopy. During video capsular endoscopy, polyps with a diameter of 2 mm to 2.5 cm were detected in the deep parts of the small intestine. For their surgical removal, during a therapeutic single-balloon enteroscopy, an electroscission of all polyps was performed. The postoperative period was uneventful. The combination of a single balloon enteroscopy with an electroexcision of polyps is suggested by the authors as the optimal method for the diagnosis and treatment of PJS in children, which allows avoiding delayed perforations of the small intestine in the postoperative period. Thanks to this technique, enteroscopy becomes the only possible alternative to bowel resection in PJS children.

scholarly journals Oral Intravascular Papillary Endothelial Hyperplasia Associated with an Organizing Thrombus: Case Report and Immunohistochemical Analysis

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Darcy Fernandes ◽  
Daphine Caxias Travassos ◽  
Túlio Morandin Ferrisse ◽  
Elaine Maria Sgavioli Massucato ◽  
Cláudia Maria Navarro ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Benign Lesion ◽  
Microscopic Analysis ◽  
Immunohistochemical Analysis ◽  
Final Diagnosis ◽  
Proliferation Index ◽  
Surgical Removal ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Ki 67 ◽  
Papillary Endothelial Hyperplasia

Intravascular papillary endothelial hyperplasia (IPEH) is a benign lesion of the skin and mucosa of vascular origin characterized by reactive proliferation of endothelial cells. A 76-year-old woman was referred presenting a painless nodule on the lip. Intraoral examination revealed bluish submucosal nodular proliferation, measuring 10 × 5 × 5 mm, affecting the lower labial mucosa. The lesion had a firm consistency and it was not fixed to the adjacent tissues. The main differential diagnoses were mucocele/mucus retention cyst, sialolith, or salivary gland neoplasia. An incisional biopsy was performed and during the intraoperative procedure an encapsulated red-bluish nodular mass was observed. Microscopic analysis revealed papillary endothelial proliferation in the center of the lesion and fibrin admixed with inflammatory cells in organization peripherally. There was no nuclear atypia, mitotic figures, or necrosis. The endothelial cells were CD34 positive, with low Ki-67 proliferation index (4%). α-SMA highlighted the vessel walls, whereas negativity for D2-40 excluded lymphatic origin. Final diagnosis was IPEH associated with an organizing thrombus. Dentists should be aware about this rare benign vascular lesion, whose final diagnosis is achieved only after histopathology analysis. Surgical removal is the treatment of choice and no recurrence is expected.

scholarly journals Malignant glomus tumor of the thyroid gland: a case report

2019 ◽  
Vol 47 (6) ◽  
pp. 2723-2727
Author(s):  
Yinhua Liu ◽  
Rongrong Wu ◽  
Tao Yu ◽  
Yingya Cao ◽  
Linming Lu
Keyword(s):  
Thyroid Gland ◽  
Smooth Muscle Actin ◽  
Final Diagnosis ◽  
Multiple Organ ◽  
Ki 67 ◽  
Glomus Tumors ◽  
Chemotherapy Drugs ◽  
Multiple Round ◽  
Initial Discovery ◽  
The Right

Objective Primary malignant glomus tumors of the thyroid gland are a rare occurrence. Methods A 68-year-old man found a mass on the right side of his neck in October 2017. An X-ray examination on 9 January 2018 showed multiple round reinforced masses in both sides of the lung. Computed tomography imaging of the neck showed a low-density mass on the right side of the thyroid gland. Results The immunohistochemistry results were positive for smooth muscle actin, calponin, collagen IV, and Ki-67 60%. The patient received chemotherapy starting on 17 January 2018, 8 February 2018, and 11 March 2018. The chemotherapy drugs included ifosfamide, epirubicin, and cisplatin. However, the patient subsequently developed multiple organ failure and died in April 2018, approximately 6 months after the initial discovery of the mass in his neck. Conclusions Primary malignant glomus tumors of the thyroid gland are rare, and examination of their pathology and immunohistochemistry is vital for making an accurate final diagnosis. This case also indicates that primary malignant glomus tumors of the thyroid gland may have a poor prognosis, despite chemotherapy.

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