scholarly journals Associations between metabolic syndrome and type of dementia: Analysis based on the National Health Insurance Service database of Gangwon province in South Korea

2020 ◽  
Author(s):  
YEO JIN KIM ◽  
Sang Mi Kim ◽  
Dae Hyun Jeong ◽  
Sang-Kyu Lee ◽  
Moo-Eob Ahn ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Insurance ◽  
National Health Insurance ◽  
National Health ◽  
High Glucose ◽  
Density Lipoprotein ◽  
High Serum ◽  
Serum Triglycerides ◽  
Previous Stroke ◽  
The Relationship

Abstract BackgroundMetabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationship between metabolic syndrome and dementia has remained controversial. Using nationwide population cohort data, we investigated the association between metabolic syndrome and dementia, according to the dementia type.MethodsWe analyzed data of 84,144 individuals, in the aged group of more than 60 years, between January 1, 2009, to December 31, 2009, at Gangwon province by using the information of the (Korean) National Health Insurance Service. After eight years of gap, in 2017, we investigated the relationship between metabolic syndrome and dementia. We classified Dementia either as dementia of the Alzheimer type (AD) or vascular dementia (VD). AD and VD were defined as per the criteria of International Classification of Disease, Tenth Revision, Clinical Modification codes. Multiple logistic regression analyses examined the associations between metabolic syndrome or five metabolic syndrome components and dementia. Analyses included factors like age, sex, smoking, alcohol, physical inactivity, previous stroke, and previous cardiac disease.ResultsMetabolic syndrome was associated with AD (OR= 11.48, 95% CI 9.03-14.59), not with VD. All five components of metabolic syndrome were associated with AD, independently. (high serum triglycerides: OR= 1.87, 95% CI 1.60-2.19; high blood pressure: OR =1.85, 95% CI 1.55-2.21; high glucose: OR= 1.77, 95% CI 1.52-2.06; abdominal obesity: OR= 1.88, 95% CI 1.57-2.25; low serum high-density lipoprotein cholesterol: OR= 1.91, 95% CI 1.63-2.24) However, among components of metabolic syndrome, only the high glucose level was associated with VD. (OR= 1.26, 95% CI= 1.01-1.56) Body Mass Index (BMI), fasting glucose, and smoking were also associated with AD. A history of the previous stroke was associated with both AD and VD.ConclusionsMetabolic syndrome was found associated with AD but not with VD. Patients with metabolic syndrome had an 11.48 times more likeliness to develop AD compared to those without metabolic syndrome. VD was associated only with several risk factors that could affect the vascular state rather than a metabolic syndrome. We suggested that the effect of metabolic syndrome on dementia would vary depending on the type of dementia.

scholarly journals Associations between metabolic syndrome and type of dementia: Analysis based on the National Health Insurance Service database of Gangwon province in South Korea

2021 ◽  
Author(s):  
YEO JIN KIM ◽  
Sang Mi Kim ◽  
Dae Hyun Jeong ◽  
Sang-Kyu Lee ◽  
Moo-Eob Ahn ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Insurance ◽  
National Health Insurance ◽  
National Health ◽  
High Glucose ◽  
Fasting Glucose ◽  
High Serum ◽  
Serum Triglycerides ◽  
Previous Stroke ◽  
The Relationship

Abstract Background Metabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationship between metabolic syndrome and dementia has remained controversial. Using nationwide population cohort data, we investigated the association between metabolic syndrome and dementia, according to the dementia type. Methods We analyzed data of 84,144 individuals, in the aged group of more than 60 years, between January 1, 2009, to December 31, 2009, at Gangwon province by using the information of the (Korean) National Health Insurance Service. After eight years of gap, in 2017, we investigated the relationship between metabolic syndrome and dementia. We classified Dementia either as dementia of the Alzheimer type (AD) or vascular dementia (VD). AD and VD were defined as per the criteria of International Classification of Disease, Tenth Revision, Clinical Modification codes. Multiple logistic regression analyses examined the associations between metabolic syndrome or five metabolic syndrome components and dementia. Analyses included factors like age, sex, smoking, alcohol, physical inactivity, previous stroke, and previous cardiac disease. Results Metabolic syndrome was associated with AD (OR= 11.48, 95% CI 9.03-14.59), not with VD. Each of five components of metabolic syndrome were also associated with AD. (high serum triglycerides: OR= 1.87, 95% CI 1.60-2.19; high blood pressure: OR =1.85, 95% CI 1.55-2.21; high glucose: OR= 1.77, 95% CI 1.52-2.06; abdominal obesity: OR= 1.88, 95% CI 1.57-2.25; low serum high-density lipoprotein cholesterol: OR= 1.91, 95% CI 1.63-2.24) However, among components of metabolic syndrome, only the high glucose level was associated with VD. (OR= 1.26, 95% CI= 1.01-1.56) Body Mass Index (BMI), fasting glucose, and smoking were also associated with AD. (BMI: OR=0.951, 95% CI= 0.927-0.975; fasting glucose: OR=1.003, 95% CI=1.001-1.005; smoking: OR=1.020, 95% CI 1.003-1.039) A history of the previous stroke was associated with both AD and VD. (AD: OR=1.827, 95% CI 1.263-2.644; VD: OR 2.775, 95% CI 1.747-4.406) Conclusions Metabolic syndrome was associated with AD but not with VD. Patients with metabolic syndrome had an 11.48 times more likeliness to develop AD compared to those without metabolic syndrome. VD was associated only with several risk factors that could affect the vascular state rather than a metabolic syndrome. We suggested that the associations between metabolic syndrome and dementia would vary depending on the type of dementia.

scholarly journals Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Yeo Jin Kim ◽  
Sang Mi Kim ◽  
Dae Hyun Jeong ◽  
Sang-Kyu Lee ◽  
Moo-Eob Ahn ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Insurance ◽  
National Health Insurance ◽  
National Health ◽  
High Glucose ◽  
Fasting Glucose ◽  
High Serum ◽  
Serum Triglycerides ◽  
Previous Stroke ◽  
The Relationship

Abstract Background Metabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationship between metabolic syndrome and dementia has remained controversial. Using nationwide population cohort data, we investigated the association between metabolic syndrome and dementia, according to the dementia type. Methods We analyzed data of 84,144 individuals, in the aged group of more than 60 years, between January 1, 2009, to December 31, 2009, at Gangwon province by using the information of the (Korean) National Health Insurance Service. After eight years of gap, in 2017, we investigated the relationship between metabolic syndrome and dementia. We classified Dementia either as dementia of the Alzheimer type (AD) or vascular dementia (VD). AD and VD were defined as per the criteria of International Classification of Disease, Tenth Revision, Clinical Modification codes. Multiple logistic regression analyses examined the associations between metabolic syndrome or five metabolic syndrome components and dementia. Analyses included factors like age, sex, smoking, alcohol, physical inactivity, previous stroke, and previous cardiac disease. Results Metabolic syndrome was associated with AD (OR = 11.48, 95% CI 9.03–14.59), not with VD. Each of five components of metabolic syndrome were also associated with AD. (high serum triglycerides: OR = 1.87, 95% CI 1.60–2.19; high blood pressure: OR = 1.85, 95% CI 1.55–2.21; high glucose: OR = 1.77, 95% CI 1.52–2.06; abdominal obesity: OR = 1.88, 95% CI 1.57–2.25; low serum high-density lipoprotein cholesterol: OR = 1.91, 95% CI 1.63–2.24) However, among components of metabolic syndrome, only the high glucose level was associated with VD. (OR = 1.26, 95% CI 1.01–1.56) body mass index (BMI), fasting glucose, and smoking were also associated with AD. (BMI: OR = 0.951, 95% CI 0.927–0.975; fasting glucose: OR = 1.003, 95% CI 1.001–1.005; smoking: OR = 1.020, 95% CI 1.003–1.039) A history of the previous stroke was associated with both AD and VD. (AD: OR = 1.827, 95% CI 1.263–2.644; VD: OR 2.775, 95% CI 1.747–4.406) Conclusions Metabolic syndrome was associated with AD but not with VD. Patients with metabolic syndrome had an 11.48 times more likeliness to develop AD compared to those without metabolic syndrome. VD was associated only with several risk factors that could affect the vascular state rather than a metabolic syndrome. We suggested that the associations between metabolic syndrome and dementia would vary depending on the type of dementia.

scholarly journals Different Effects of Metabolic Syndrome on Dementia According to Dementia Type: Analysis Based on the National Health Insurance Service Database of Gangwon Province in South Korea

2020 ◽  
Author(s):  
YEO JIN KIM ◽  
Sang Mi Kim ◽  
Dae Hyun Jeong ◽  
Sang-Kyu Lee ◽  
Moo-Eob Ahn ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Insurance ◽  
National Health Insurance ◽  
National Health ◽  
International Classification Of Disease ◽  
History Of ◽  
Korean National Health Insurance ◽  
High Glucose Level ◽  
The Relationship

Abstract BackgroundMetabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationshipbetween metabolic syndrome and dementia has remained controversial. Using nationwide population cohort data, we investigated the associationbetween metabolic syndrome and dementia,according to the dementia type.MethodsWe analyzed data of 84,144 individuals,in the aged group of more than 60 years,between January 1, 2009,to December 31, 2009, at Gangwon province by using the information of the(Korean) National Health Insurance Service. After eight years of gap, in 2017, we investigated the relationship between metabolic syndrome and dementia. We classified Dementia either as dementia of the Alzheimer type (AD) or vascular dementia (VD). AD and VD were defined according to criteria in the International Classification of Disease, Tenth Revision, Clinical Modification codes.ResultsMetabolic syndrome was associated with AD, while it was not associated with VD. All five components of metabolic syndrome were associated with AD, independently. However, among components of metabolic syndrome, only the high glucose level was associated with VD. Body Mass Index (BMI), fasting glucose and smoking were also associated with AD. A history of the previous stroke was associated with both AD and VD.ConclusionsMetabolic syndrome was associated with AD, while was not associated with VD. VD was associated only with several risk factors that could affect the vascular state rather than a metabolic syndrome. We suggested that the effect of metabolic syndrome on dementia would be different depending on the type of dementia.

scholarly journals Changes in metabolic syndrome and risk of psoriasis: a nationwide population-based study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyun Ji Lee ◽  
Kyung Do Han ◽  
Hae Eun Park ◽  
Ju Hee Han ◽  
Chul Hwan Bang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Insurance ◽  
Waist Circumference ◽  
Confidence Interval ◽  
Density Lipoprotein ◽  
Population Based ◽  
Control Group ◽  
Newly Diagnosed ◽  
Population Based Study ◽  
The Relationship

AbstractMetabolic syndrome (MetS) is associated with psoriasis, but it remains unclear whether risk of psoriasis remains in patients whose MetS diagnosis changes. To assess the relationship between risk of psoriasis and changes in MetS components. We obtained data from the National Health Insurance Service of Korea and divided the participants into four groups: individuals without MetS (control); individuals with MetS in 2009, but without MetS in 2012 (pre-MetS); individuals without MetS in 2009, but with newly diagnosed MetS in 2012 (post-MetS); and individuals with MetS during the 2009–2012, period (continuous-MetS). We calculated the risk of psoriasis for each group. Risk of psoriasis was similar in the control and pre-MetS groups but was significantly higher in the post-MetS group (hazard ratio [HR], 1.08; 95% confidence interval [CI], 1.04–1.12) and in the continuous-MetS group (HR, 1.11; 95% CI, 1.07–1.15) than in the control group. Among MetS components, waist circumference showed the strongest association with psoriasis, followed by high-density lipoprotein and triglyceride levels. Risk of psoriasis was higher in patients with continuous- or post-MetS than in those with pre-MetS (regardless of prior MetS status).

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