scholarly journals An online GPCR structure analysis platform

Author(s):  
David Gloriam ◽  
Albert Kooistra ◽  
Christian Munk ◽  
Alexander Hauser

Abstract We present an online, interactive platform for comparative analysis of all available G protein-coupled receptor structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied research studies.

Author(s):  
Adam Bryant Miller ◽  
Maya Massing-Schaffer ◽  
Sarah Owens ◽  
Mitchell J. Prinstein

Nonsuicidal self-injury (NSSI) is direct, intentional harm to one’s own body performed without the intent to die. NSSI has a marked developmental onset reaching peak prevalence in adolescence. NSSI is present in the context of multiple psychological disorders and stands alone as a separate phenomenon. Research has accumulated over the past several decades regarding the course of NSSI. While great advances have been made, there remains a distinct need for basic and applied research in the area of NSSI. This chapter reviews prevalence rates, correlates and risk factors, and leading theories of NSSI. Further, it reviews assessment techniques and provides recommendations. Then, it presents the latest evidence-based treatment recommendations and provides a case example. Finally, cutting edge research and the next frontier of research in this area are outlined.


2017 ◽  
Vol 93 (2) ◽  
pp. 387-388
Author(s):  
Eugene S. Vysotski

2005 ◽  
Vol 41 (2) ◽  
pp. 151-158
Author(s):  
V. V. Vainshtok ◽  
N. S. Smirnova ◽  
A. S. Skobel’tsin

2013 ◽  
Vol 804 ◽  
pp. 70-75 ◽  
Author(s):  
Jian-Hua Huang ◽  
Hua-Lin Xie ◽  
Jun Yan ◽  
Hong-Mei Lu ◽  
Qing-Song Xu ◽  
...  

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