scholarly journals Characteristics of hepatic solitary necrotic nodules on contrast-enhanced ultrasonography

2021 ◽  
Author(s):  
Chunyu Lu ◽  
Shaoshan Tang ◽  
Xiaoyue Zhang ◽  
Yang Wang ◽  
Kaiming Wang ◽  
...  
Keyword(s):  
The Other ◽  
Arterial Phase ◽  
Focal Lesions ◽  
Multiple Lesions ◽  
Portal Phase ◽  
Contrast Enhanced ◽  
The Us ◽  
Contrast Enhanced Ultrasonography ◽  
Dynamic Enhancement ◽  
Three Phases

Abstract Background:To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS).Methods:Conventional ultrasonography (US) and CEUS were performed in 24 patients who were confirmed to have SNN by pathological assessment. The US data and dynamic enhancement patterns of CEUS were recorded and retrospectively analyzed.Results:Ten of 24 patients underwent surgical resection, while the other 14 patients underwent a puncture biopsy to be confirmed as SNN. Among the 24 patients, 13 patients had a single lesion and 11 patients had multiple lesions. The largest lesion was selected for CEUS examination for patients with multiple lesions. Eleven patients presented no enhancement in all three phases, while the other 13 patients presented with a peripheral thin rim-like enhancement in the arterial phase, an iso-enhancement in the portal phase and delayed phase. However, no enhancement in the interior of the lesions was detected during three phases of CEUS.Conclusions:SNN has characteristic findings on the CEUS, which play an important role in the differential diagnoses of liver focal lesions.

scholarly journals Characteristics of hepatic solitary necrotic nodules on contrast-enhanced ultrasonography

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chunyu Lu ◽  
Shaoshan Tang ◽  
Xiaoyue Zhang ◽  
Yang Wang ◽  
Kaiming Wang ◽  
...  
Keyword(s):  
The Other ◽  
Arterial Phase ◽  
Focal Lesions ◽  
Multiple Lesions ◽  
Portal Phase ◽  
Contrast Enhanced ◽  
The Us ◽  
Contrast Enhanced Ultrasonography ◽  
Dynamic Enhancement ◽  
Three Phases

Abstract Background To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS). Methods Conventional ultrasonography (US) and CEUS were performed in 24 patients who were confirmed to have SNN by pathological assessment. The US data and dynamic enhancement patterns of CEUS were recorded and retrospectively analyzed. Results Ten of 24 patients underwent surgical resection, while the other 14 patients underwent a puncture biopsy to be confirmed as SNN. Among the 24 patients, 13 patients had a single lesion and 11 patients had multiple lesions. The largest lesion was selected for CEUS examination for patients with multiple lesions. Eleven patients presented no enhancement in all three phases, while the other 13 patients presented with a peripheral thin rim-like enhancement in the arterial phase, an iso-enhancement in the portal phase and delayed phase. However, no enhancement in the interior of the lesions was detected during three phases of CEUS. Conclusions SNN has characteristic findings on the CEUS, which play an important role in the differential diagnoses of liver focal lesions.

scholarly journals Characteristics of hepatic solitary necrotic nodules on contrast-enhanced ultrasonography

2020 ◽  
Author(s):  
Chunyu Lu ◽  
Shaoshan Tang ◽  
Xiaoyue Zhang ◽  
Yang Wang ◽  
Kaiming Wang ◽  
...  
Keyword(s):  
Differential Diagnoses ◽  
Arterial Phase ◽  
Focal Lesions ◽  
Portal Phase ◽  
Contrast Enhanced ◽  
The Us ◽  
Contrast Enhanced Ultrasonography ◽  
Dynamic Enhancement ◽  
Delayed Phase ◽  
Single Lesion

Abstract Background:To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS), and to improve the differential diagnoses value of CEUS on liver focal lesions.Methods:Conventional ultrasonography (US) and CEUS were performed in 24 patients who were confirmed to have SNN by pathological assessment. The US data and dynamic enhancement patterns of CEUS were recorded and retrospectively analyzed.Results:All patients underwent CEUS, and of these, 10 patients underwent surgical resection, while 14 patients underwent a puncture biopsy to confirm SNN. Among the 24 patients, 13 patients had a single lesion and 11 patients had multiple lesions. Eleven patients presented no enhancement in all three phases, while the other 13 patients presented with a peripheral thin rim-like enhancement in the arterial phase, an iso-enhancement in the portal phase and delayed phase, and no enhancement in the interior of the lesions. Conclusions:SNN has characteristic findings on the CEUS, which play an important role in the differential diagnoses of liver focal lesions.

scholarly journals Characteristics of hepatic solitary necrotic nodules on contrast-enhanced ultrasonography

2020 ◽  
Author(s):  
Chunyu Lu ◽  
Shaoshan Tang ◽  
Xiaoyue Zhang ◽  
Yang Wang ◽  
Kaiming Wang ◽  
...  
Keyword(s):  
Arterial Phase ◽  
Focal Lesions ◽  
Portal Phase ◽  
Contrast Enhanced ◽  
The Us ◽  
Puncture Biopsy ◽  
Contrast Enhanced Ultrasonography ◽  
Dynamic Enhancement ◽  
Delayed Phase ◽  
Single Lesion

Abstract Background:To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS).Methods:Conventional ultrasonography (US) and CEUS were performed in 24 patients who were confirmed to have SNN by pathological assessment. The US data and dynamic enhancement patterns of CEUS were recorded and retrospectively analyzed.Results:All patients underwent CEUS, and of these, 10 patients underwent surgical resection, while 14 patients underwent a puncture biopsy to confirm SNN. Among the 24 patients, 13 patients had a single lesion and 11 patients had multiple lesions，the largest lesion was selected for CEUS examination. Eleven patients presented no enhancement in all three phases, while the other 13 patients presented with a peripheral thin rim-like enhancement in the arterial phase, an iso-enhancement in the portal phase and delayed phase, and no enhancement in the interior of the lesions. Conclusions:SNN has characteristic findings on the CEUS, which play an important role in the differential diagnoses of liver focal lesions.

MO226A NEW DIAGNOSTIC TOOL FOR CKD PATIENTS: CONTRAST-ENHANCED ULTRASONOGRAPHY. A SINGLE CENTER EXPERIENCE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Mirela Liana Gliga ◽  
Cristian Chirila ◽  
Paula Chirila ◽  
Adriana Gomotarceanu ◽  
Imola Torok ◽  
...  
Keyword(s):  
Diagnostic Tool ◽  
Final Diagnosis ◽  
Medical System ◽  
Focal Lesions ◽  
Non Invasive ◽  
Single Center Experience ◽  
Contrast Enhanced ◽  
Contrast Enhanced Ultrasonography ◽  
Malignant Lesions ◽  
Guidelines And Recommendations

Abstract Background and Aims Contrast-enhanced ultrasonography (CEUS) is a minimally invasive diagnostic tool available for diagnosing microvascular disturbances in tumors and many vascular pathologies. Unlike other radiological contrast agents, it is completely harmless for CKD patients and therefore it is used for the safe diagnosis of many diffuse or focal pathologies. Method We used CEUS examination in 50 CKD patients for the following pathologies: 10 atypical cysts, 15 liver focal lesions, 2 splenic focal lesions, 3 renal infarcts, 12 kidney focal lesions and 8 other organ involvements. Examination was made using a VOLUSON E8 machine (GE Medical System Kreztechnik GmbH Tiefenbach 15, Austria) with a 3.5 MHz convex array abdominal transducer. 2.4 ml of microbubble contrast-agent was administered intravenously and recording of the results were made for 3-5 minutes after injection. Results Depending on the organ vascular characteristics, contrast enhancement and/or wash-out were suggestive for the final diagnosis. In liver lesions there are three phases and in kidneys, spleen, gallbladder, adenopathies there are two vascular phases. We obtained a very good positive predictive value and sensitivity in detecting malignant lesions. Conclusion According to The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound they are used both for hepatic and Non-Hepatic Applications. Being non-invasive and non-irradiating it could be the main diagnostic examination in CKD population in the future.

scholarly journals Use of Contrast-Enhanced Ultrasonography for the Characterization of Tumor Thrombi in Seven Dogs

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1613
Author(s):  
Alessia Cordella ◽  
Pascaline Pey ◽  
Nikolina Linta ◽  
Manuela Quinci ◽  
Marco Baron Toaldo ◽  
...  
Keyword(s):  
Color Doppler ◽  
Case Series ◽  
Arterial Phase ◽  
Retrospective Case ◽  
Primary Tumors ◽  
Contrast Enhanced ◽  
Venous Phase ◽  
Contrast Enhanced Ultrasonography ◽  
Tumor Thrombi

Tumors of adrenal and thyroid glands have been associated with vascular invasions—so-called tumor thrombi, both in humans and dogs. The detection and characterization of venous thrombi is an important diagnostic step in patients with primary tumors for both surgical planning and prognosis. The aim of this study was to describe the use of contrast-enhanced ultrasonography (CEUS) for the characterization of tumor thrombi. Dogs with tumor thrombus who underwent bi-dimensional ultrasound (B-mode US) and CEUS were included. Seven dogs were enrolled in this retrospective case series. On B-mode US, all thrombi were visualized, and vascular distension and thrombus-tumor continuity were seen in three and two cases, respectively. On color Doppler examination, all thrombi were identified, seemed non-occlusive and only two presented vascularity. On CEUS, arterial-phase enhancement and washout in the venous phase were observed in all cases. Non-enhancing areas were identified in the tumor thrombi most likely representing non-vascularized tissue that could potentially be embolized in the lungs after fragmentation of the tumor thrombi. On the basis of these preliminary study, CEUS appeared to be useful for the characterization of malignant intravascular invasion.

Differentiation of intrapancreatic accessory spleen from small hypervascular neuroendocrine tumor of the pancreas: textural analysis on contrast-enhanced computed tomography

2018 ◽  
Vol 60 (5) ◽  
pp. 553-560 ◽  
Author(s):  
Xubo Lin ◽  
Lei Xu ◽  
Aiqin Wu ◽  
Chuangen Guo ◽  
Xiao Chen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lymph Node ◽  
Roc Analysis ◽  
Texture Features ◽  
Arterial Phase ◽  
Portal Phase ◽  
Contrast Enhanced ◽  
Lymph Node Enlargement ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Background Intrapancreatic accessory spleens (IPASs) are usually misdiagnosed as pancreatic neuroendocrine tumors (PNETs). Texture analysis is valuable in tumor detection, diagnosis, and staging. Purpose To identify the potential of texture features in differentiating IPASs from small hypervascular PNETs. Material and Methods Twenty-one patients with PNETs and 13 individuals with IPASs who underwent pretreatment dynamic contrast-enhanced computed tomography (CT) were retrospectively analyzed. The routine imaging features—such as location, size, margin, cystic or solid appearance, enhancement degree and pattern, and lymph node enlargement—were recorded. Texture features, such as entropy, skewness, kurtosis, and uniformity, on contrast-enhanced images were analyzed. Receiver operating characteristic (ROC) analysis was performed to differentiate IPASs from PNETs. Results No significant differences were observed in margin, enhancement degree (arterial and portal phase), lymph node enlargement, or size between PNETs and IPASs (all P > 0.05). However, IPASs usually showed heterogeneous enhancement at the arterial phase and the same degree of enhancement as the spleen at the portal phase, both of which were greater than those of PNETs (69% vs. 35%, P = 0.06; 100% vs. 29%, P = 0.04). Entropy and uniformity were significantly different between IPASs and PNETs at moderate (1.5) and high sigma values (2.5) (both P < 0.01). ROC analysis showed that uniformity at moderate and high sigma had the highest area under the curve (0.82 and 0.89) with better sensitivity (85.0–95.0%) and acceptable specificity (75.0–83.3%) for differentiating IPASs from PNETs. Conclusions Texture parameters have potential in differentiating IPASs from PNETs.

Doppler ultrasonography and contrast-enhanced ultrasonography to evaluate liver allograft discard: A pilot prospective study

2020 ◽  
pp. 1-8
Author(s):  
Hong-jun Zhang ◽  
Bo-wen Zheng ◽  
Shi-jie Gu ◽  
Tao Wu ◽  
Li-li Wu ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Doppler Ultrasonography ◽  
Multivariable Analysis ◽  
Peak Time ◽  
Donor Liver ◽  
Hemodynamic Changes ◽  
Predictive Tool ◽  
Contrast Enhanced ◽  
The Us ◽  
Contrast Enhanced Ultrasonography

BACKGROUND: Broad hemodynamic changes, is believed to have a profoundly damaging effect on donor livers after brain death (DBD) or cardiac death (DCD). It remains unclear whether Doppler ultrasonography (DUS) and contrast-enhanced ultrasonography (CEUS), the imaging modalities to evaluate perfusion, could provide more information of liver discarded. OBJECTIVE: To evaluate the ability of DUS and CEUS to predict the risk of DBD or DCD liver discarded. METHODS: The consecutive DBD or DCD donors with DUS/CEUS examinations before surgical procurement from February 2016 to June 2018 at our institution were included. The US and CEUS images of each donor liver were analyzed and the parameters were recorded. RESULTS: Among the 67 eligible donor livers, 15 (22.4%) were discarded and 52 (77.6%) were used. The discarded livers showed prolonged SAT of hepatic artery (0.08s vs 0.06s, OR = 2.169, P = 0.008) on DUS, less cases with homogeneous enhancement (40.0% vs 73.1%, OR = 0.243, P = 0.028) on CEUS, more cases with decreased enhancement (46.7% vs 15.4%, OR = 4.813, P = 0.011), and less difference of the peak time between portal vein and liver parenchymal (0.5s vs 6.7s, OR = 4.260, P = 0.015). The multivariable analysis showed that donor liver with prolonged SAT of hepatic artery (OR = 7.304, 95% CI: 1.195–44.655, P = 0.031) and decreased enhancement (OR = 2.588, 95% CI: 1.234–5.426, P = 0.012) were independent factors of liver discarded. CONCLUSIONS: DUS/CEUS could be applied as a promising predictive tool to screen high-risk liver donors. The prolonged SAT of hepatic artery on DUS and the decrease of liver donor in enhancement on CEUS, indicating hemodynamic changes in DBD and DCD donor livers, were risk factors of liver discarded.

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