scholarly journals High-sensitivity biosensor for simultaneous detection of cancer and diabetes using photonic crystal microstructure

2021 ◽  
Author(s):  
Mojtaba Hosseinzadeh Sani ◽  
Ashkan Ghanbari ◽  
Hamed Saghaei
Keyword(s):  
Refractive Index ◽  
Integrated Circuits ◽  
Hexagonal Lattice ◽  
Simultaneous Detection ◽  
High Sensitivity ◽  
Laser Source ◽  
Refractive Index Sensor ◽  
Detection Range ◽  
Sensitivity Range ◽  
Silicon Rods

Abstract In this study, we propose a refractive index sensor for the simultaneous detection of cancer and diabetes based on photonic crystals (PhC). The proposed PhC composed of silicon rods in the air bed arranged in a hexagonal lattice forms the fundamental structure, and two tubes are used to place the cancerous or diabetic samples for measurement. The sensor's transmission characteristics are simulated and analyzed by solving Maxwell's electromagnetic equations using the finite-difference time-domain method for samples under study. The diagnosis of three types of cancer and diabetes is based on changing the samples' refractive index by applying the laser source centered at 1550 nm. Our results demonstrate that the proposed structure's quality factor and sensitivity can be adjusted by changing the sensor's geometry. They reveal that the transmission power is between 91% ~ 100%, depending on the sample. The sensitivity range is also between 1294 and 3080 nm/RIU. The maximum figure of merit is about 1550.11 RIU− 1 with a detection range of 31×10− 6 RIU. The small biosensor area of ​​ 61.56 µm2 makes it a suitable device for various applications in compact photonic integrated circuits.

scholarly journals Ultra-Sensitive Biosensor with Simultaneous Detection (of Cancer and Diabetes) and Analysis of Deformation Effects on Dielectric Rods in Optical Microstructure

Coatings ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1564
Author(s):  
Supat Chupradit ◽  
Shameen Ashfaq ◽  
Dmitry Bokov ◽  
Wanich Suksatan ◽  
Abduladheem Turki Jalil ◽  
...  
Keyword(s):  
Refractive Index ◽  
Integrated Circuits ◽  
Hexagonal Lattice ◽  
Simultaneous Detection ◽  
Laser Source ◽  
Refractive Index Sensor ◽  
Detection Range ◽  
Optical Microstructure ◽  
Silicon Rods ◽  
Difference Time

This study proposes a refractive index sensor for the simultaneous detection of cancer and diabetes based on photonic crystals (PhC). The proposed PhC composed of silicon rods in the air bed arranged in a hexagonal lattice forms the fundamental structure. Two tubes are used to place the cancerous or diabetic samples for measurement. The sensor’s transmission characteristics are simulated and analyzed by solving Maxwell’s electromagnetic equations using the finite-difference time-domain approach for samples being studied. Therefore, diabetes and cancer are detected according to the changes in the refractive index of the samples using the laser source centered at 1550 nm. Considering the findings, the sensor’s geometry changes to adjust the suggested sensitivity and quality factor of structure. According to the results, transmission power ranges between 91 and 100% based on the sample. Moreover, sensitivity ranges from 1294 to 3080 nm/RIU and the maximum Figure of Mertie is nearly FOM = 1550.11 ± 150.11 RIU−1 with the detection in range 31 × 10−6 RIU. In addition, the small area (61.56 μm2) of biosensor results in its appropriateness for different uses in compact photonic integrated circuits. Next, we changed the shape of the dielectric rods and investigated their effects on the sensitivity parameter. The sensitivity and figure of merit after changes in the shape of dielectric rods and nanocavities are at best S = 20,393 nm/RIU and FOM = 9104.017 ± 606.93 RIU−1, receptively. In addition, the resolution detection range is 203.93 × 10−6 RIU.

scholarly journals High Sensitivity Refractive Index Sensor Based on Dual-Core Photonic Crystal Fiber with Hexagonal Lattice

Sensors ◽  
2016 ◽  
Vol 16 (10) ◽  
pp. 1655 ◽  
Author(s):  
Haiyang Wang ◽  
Xin Yan ◽  
Shuguang Li ◽  
Guowen An ◽  
Xuenan Zhang
Keyword(s):  
Refractive Index ◽  
Photonic Crystal ◽  
Photonic Crystal Fiber ◽  
Hexagonal Lattice ◽  
High Sensitivity ◽  
Refractive Index Sensor ◽  
Crystal Fiber ◽  
Dual Core

High sensitivity refractive index sensor based on micro-fiber with micro-arched transition

2019 ◽  
Vol 50 ◽  
pp. 13-18 ◽  
Author(s):  
Zengshan Xing ◽  
Yanzhen Wang ◽  
Li Tang ◽  
Jianhui Yu ◽  
Heyuan Guan ◽  
...  
Keyword(s):  
Refractive Index ◽  
High Sensitivity ◽  
Refractive Index Sensor

scholarly journals Simultaneous Measurement of Temperature and Refractive Index Using High Temperature Resistant Pure Quartz Grating Based on Femtosecond Laser and HF Etching

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1028
Author(s):  
Na Zhao ◽  
Qijing Lin ◽  
Kun Yao ◽  
Fuzheng Zhang ◽  
Bian Tian ◽  
...  
Keyword(s):  
Refractive Index ◽  
High Temperature ◽  
Femtosecond Laser ◽  
Optical Fiber ◽  
Temperature Response ◽  
High Sensitivity ◽  
Xrd Analysis ◽  
Refractive Index Sensor ◽  
Compact Structure ◽  
Fluid Analysis

The optical fiber temperature and refractive index sensor combined with the hollow needle structure for medical treatment can promote the standardization of traditional acupuncture techniques and improve the accuracy of body fluid analysis. A double-parameter sensor based on fiber Bragg grating (FBG) is developed in this paper. The sensor materials are selected through X-ray diffraction (XRD) analysis, and the sensor sensing principle is theoretically analyzed and simulated. Through femtosecond laser writing pure silica fiber, a high temperature resistant wavelength type FBG temperature sensor is obtained, and the FBG is corroded by hydrofluoric acid (HF) to realize a high-sensitivity intensity-type refractive index sensor. Because the light has dual characteristics of energy and wavelength, the sensor can realize simultaneous dual-parameter sensing. The light from the lead-in optical fiber is transmitted to the sensor and affected by temperature and refractive-index; then, the reflection peak is reflected back to the lead-out fiber by the FBG. The high temperature response and the refractive index response of the sensor were measured in the laboratory, and the high temperature characteristics of the sensor were verified in the accredited institute. It is demonstrated that the proposed sensor can achieve temperature sensing up to 1150 °C with the sensitivity of 0.0134 nm/°C, and refractive sensing over a refractive range of 1.333 to 1.4027 with the sensitivity of −49.044 dBm/RIU. The sensor features the advantages of two-parameter measurement, compact structure, and wide temperature range, and it exhibits great potential in acupuncture treatment.

High sensitivity fiber refractive index sensor using tapered 4-core fiber

2021 ◽  
Author(s):  
Zhen Tian ◽  
Lina Suo ◽  
Nan-Kuang Chen ◽  
Yicun Yao ◽  
Liqiang Zhang ◽  
...  
Keyword(s):  
Refractive Index ◽  
High Sensitivity ◽  
Refractive Index Sensor ◽  
Core Fiber
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