scholarly journals Meta-analysis on the Impact of Positive Psychological Resources on Quality of Life in Cancer Patients

2021 ◽  
Author(s):  
Xinxin Zhao ◽  
Siqi Tong ◽  
Ye Yang
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Sensitivity Analyses ◽  
Future Research ◽  
Psychological Resources ◽  
The Impact

Abstract Purpose: The main purpose of this study was to assess the evidence of the association between positive psychological resources and quality of life among cancer patients. Methods: Electronic search was performed to retrieve articles from PubMed, Web of Science, CNKI and CBM (from inception to November 10, 2020). Summary correlation coefficient (r) values were extracted from each study, and 95% confidence intervals (95%CIs) were calculated by random-effect model. Subgroup and sensitivity analyses were performed to investigate potential heterogeneity.Results: Forty-three articles were included in the present study. The pooled r for resilience was 0.52 (95%CI: 0.43, 0.62), hope 0.50 (95%CI: 0.44, 0.56), self-efficacy 0.54 (95%CI: 0.41, 0.63), self-esteem 0.45 (95%CI: 0.26, 0.64) and optimism 0.32 (95%CI: 0.17, 0.46). For subgroup analysis, the effects of hope and resilience varied with patients’ age.Conclusion: Our study indicated that cancer patients with high level of positive psychological resources tend to live a better quality of life. Therefore, interventions programs based on difference in age for cancer patients could be developed by increasing positive psychological resources in the future research.

scholarly journals Cancer Caregiver Quality of Life: Meta-Analysis

2021 ◽  
Author(s):  
Kusum K Rohilla ◽  
C Vasantha Kalyani ◽  
Amit Gupta ◽  
Sweety Gupta ◽  
Manoj Gupta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Mean Difference ◽  
Final Report ◽  
Intervention Programme ◽  
Cancer Caregivers ◽  
The Impact

Abstract People living with cancer benefit greatly from informal caregivers. There has never been a previous meta-analysis on the quality of life of cancer caregivers or the efficacy of caregiver intervention programmes. The goal of this meta-analysis was to look at the quality of life of cancer caregivers and the impact of various initiatives aimed at improving it. From January 2006 to April 2021, a comprehensive literature search was conducted using PubMed, PubMed Central, Clinical Key, Google Scholar and Cochrane database. The effect of caregiver interventional programs on quality of life was evaluated using a mean difference between experimental and control groups. A random-effect model was used to measure the risk ratio (RR) for calculating the quality of life of cancer caregivers. The final report comprised eight trials with a total of 1142 participants. The caregiver intervention programme was found to improve the quality of life of cancer caregivers, but not statistically significantly (mean difference=0.10; p<0.00001). A caregiver interventional program had a positive effect on the quality of life of cancer caregivers, according to this meta-analysis. To prove that caregiver interventional programs are successful strategies for improving the quality of life of cancer caregivers, further randomised controlled trials are required.

scholarly journals Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hesam Ghiasvand ◽  
Katherine M. Waye ◽  
Mehdi Noroozi ◽  
Gholamreza Ghaedamini Harouni ◽  
Bahram Armoon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Confidence Interval ◽  
Effect Size ◽  
Meta Analysis ◽  
Random Effect Model ◽  
Cd4 Count ◽  
Co Morbidity ◽  
The Impact ◽  
Hiv Aids

Abstract Background During recent years, Quality of Life (QoL) is a significant assessment factor in clinical trials and epidemiological researches due to the advent of Antiretroviral Therapy (ART), Human Immunodeficiency Virus (HIV) has become a manageable,chronic disease. With regards, more attention must be paid to the QoL of infected patients. Limited evidence exists on the impact of ART on QoL among HIV infected patients. Due to lacking of a systematic approach to summarizing the available evidence on the clinical determinants of People Who Live with HIV/AIDS (PWLHs’) QoL, this study aimed to analyze the impact of clinical determinants (ART experience, CD4 count < 200, co-morbidities, time diagnosis and accessibility to cares) on QoL among PWLHs’. Methods This study was designed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). PubMed, Science Direct, Web of Science, and Cochrane electronic databases were searched in February 2017 to identify all past studies that discussed social and behavioral characteristics of QoL in PLWHA. To recognize effective factors on social and behavioral QoL, a meta-analysis was conducted. Polled Odds Ratios (ORs) were utilized at a 95% confidence level. Since sampling methods differed between articles in the systematic review, we evaluated pooled estimates using a random effect model. Metan, metareg, metacum, and metabias commands in STATA version 13.0 were applied to analyze the data. Results Our findings indicated that ART has a positive impact on QoL, with a pooled effect size at approximately 1.04 with a confidence interval between 0.42 to 1.66 which indicates this impact is not very considerable and may be relatively neutral. The pooled effect size for CD4 count on QoL was .29 (95%CI = .22–.35), indicating that there is a negative associate between CD4 count and QoL. The co-morbidity as a negative determinant for QoL among HIV/AIDS infected people. The pooled effect size implies on a relative neutral association, although the confidence interval is wide and ranges between 0.32 to 1.58. The pooled effect size is about 1.82 with confidence interval 1.27 to 2.37 which indicates a considerable positive association with lowest level of heterogeneity. Conclusions The results illustrated that time diagnosing and availability to hospital services had significant relationship with a higher QoL and CD4 < 200 was associated with a lower QoL. In conclusion, policy makers should set an agenda setting to provide a suitable diagnostic and therapeutic facilities to early detecting and continues monitoring the health status of People Who Live with HIV/AIDS (PWLHs’).

scholarly journals The impact of informing diagnosis on quality of life in patients with cancer: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Miao Wan ◽  
Xianggui Luo ◽  
Louis.B NDZANA MVOGO ◽  
Juan Wang ◽  
Chen Chang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Cognitive Activity ◽  
Biomedical Literature ◽  
Cochrane Central Register ◽  
Patients With Cancer ◽  
General Quality ◽  
The Impact

Abstract Objective To assess the impact of informing diagnosis and disease status on the quality of life in patients with cancer Method We searched the follow databases, Pubmed, CENTRAL(Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase, CBM (Chinese Biomedical Literature database), WANFANG database (Chinese Medicine Premier), and CNKI (China National Knowledge Infrastructure). And the terms used are as follows: neoplasm, cancer, tumour, tumor, carcinoma, disclosure, truth telling, breaking bad news, knowledge, knowing, awareness, quality of life, QOL. Pairs of reviewers independently screened documents and extracted the data. Meta-analysis was conducted by Revman 5.0 software. Results There were 11740 records retrieved from databases and 23 studies were included finally. Meta-analysis of informed and uniformed cancer patients revealed no differences in both the general quality of life and symptoms of fatigue, pain, dyspnea, insomnia, appetite loss and diarrhea (P>0.05). Additionally, no difference in physical function, role function, cognitive activity and emotional function between the above 2 groups(P>0.05) were found. On the vitality area, the patients who were totally informed about their diagnosis had higher vitality than the uniformed patients. However, patients aware about their illnesses seemed to get lower scores in social function. Between the partly informed of the diagnosis and uninformed cancer patients, there were no differences in general quality of life, function domains and disease-related symptoms (P>0.05). Conclusion Informing the cancer patients their diagnosis may not have a bad effect on their quality of life. PROSPERO registration number CRD42017060073.

The impact of SLE on health-related quality of life assessed with SF-36: a systemic review and meta-analysis

Lupus ◽  
2019 ◽  
Vol 28 (3) ◽  
pp. 371-382 ◽  
Author(s):  
M Gu ◽  
Q Cheng ◽  
X Wang ◽  
F Yuan ◽  
NB Sam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Meta Analysis ◽  
Random Effect ◽  
Systemic Review ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Objective To evaluate the impact of systemic lupus erythematosus (SLE) on health-related quality of life (HRQoL) assessed with SF-36 and explore factors associated with HRQoL in SLE patients. Methods A random-effect meta-analysis was performed to calculate extracted data. Sensitivity and subgroup analyses were performed to distinguish sources of heterogeneity. Results A total of 36 articles were finally included in this meta-analysis, including 6510 patients. The pooled mean scores of SF-36 physical component summary and mental component summary were 46.10 (95% confidence interval (CI): 43.09–49.10) and 50.37 (95% CI: 47.78–52.87), respectively. Spearman's correlation analysis found that mean age, proportion of female participants, and publication decades were negatively associated with some of the SF-36 domains. Sample size and SLEDAI were positively associated with some of the SF-36 domains. Patients with SLE have lower HRQoL in comparison to the general population. Conclusions SLE has a significant impact on HRQoL, which proves that the necessity of improving HRQoL in SLE patients cannot be ignored. Measuring HRQoL should be considered as an indispensable part of the overall evaluation of health conditions of SLE patients.

scholarly journals The Impact of Malocclusion/Orthodontic Treatment Need on the Quality of Life

2009 ◽  
Vol 79 (3) ◽  
pp. 585-591 ◽  
Author(s):  
Zhijian Liu ◽  
Colman McGrath ◽  
Urban Hägg
Keyword(s):  
Quality Of Life ◽  
Orthodontic Treatment ◽  
Meta Analysis ◽  
Current Evidence ◽  
Future Research ◽  
Evidence Based ◽  
Treatment Need ◽  
Methodologic Quality ◽  
The Impact

Abstract Objective: To assess the current evidence of the relationship between malocclusion/orthodontic treatment need and quality of life (QoL). Materials and Methods: Four electronic databases were searched for articles concerning the impact of malocclusion/orthodontic treatment need on QoL published between January 1960 and December 2007. Electronic searches were supplemented by manual searches and reference linkages. Eligible literature was reviewed and assessed by methodologic quality as well as by analytic results. Results: From 143 reviewed articles, 23 met the inclusion criteria and used standardized health-related QoL (HRQoL) and orthodontic assessment measures. The majority of studies (18/23) were conducted among child/adolescent populations. Seventeen of the papers were categorized as level 1 or 2 evidence based on the criteria of the Oxford Centre for Evidence-Based Medicine. An observed association between HRQoL and malocclusion/orthodontic treatment need was generally detected irrespective of how they were assessed. However, the strength of the association could be described as modest at best. Key findings and future research considerations are described in the review. Conclusions: Findings of this review suggest that there is an association (albeit modest) between malocclusion/orthodontic treatment need and QoL. There is a need for further studies of their relationship, particularly studies that employ standardized assessment methods so that outcomes are uniform and thus amenable to meta-analysis.

scholarly journals Effects of vitamin D supplementation on apolipoprotein A1 and B100 levels in adults: Systematic review and meta-analysis of controlled clinical trials

2021 ◽  
Vol 13 (3) ◽  
pp. 190-197
Author(s):  
Nima Radkhah ◽  
Sakineh Shabbidar ◽  
Meysam Zarezadeh ◽  
Abdolrasoul Safaeiyan ◽  
Ali Barzegar
Keyword(s):  
Vitamin D ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Vitamin D Supplementation ◽  
Mean Difference ◽  
Apolipoprotein A1 ◽  
Sensitivity Analyses ◽  
Standardized Mean Difference ◽  
The Impact

Cardiovascular disease (CVD) is a leading cause of death around the world. According to the studies, apolipoproteins A1 and B100 play crucial role in CVD development and progression. Also, findings have indicated the positive role of vitamin D on these factors. Thus, we conducted the present meta-analysis of randomized controlled trials (RCTs) to demonstrate the impact of vitamin D supplementation on apolipoproteins A1 and B100 levels in adults. PubMed and Scopus databases and Google Scholar were searched up to 21 December 2020. Relevant articles were screened, extracted, and assessed for quality based on the Cochrane collaboration’s risk of bias tool. Data analysis conducted by random-effect model and expressed by standardized mean difference (SMD). The heterogeneity between studies was assessed by I-squared (I2) test. Subgroups and sensitivity Analyses were also conducted. Seven RCTs were identified investigating the impact of vitamin D on Apo A1 levels and six on Apo B100 levels. The findings showed the insignificant effect of vitamin D supplementation on Apo A1 (SMD=0.26 mg/dL; 95% confidence interval (CI), −0.10, 0.61; P= 0.155) and Apo B100 (standardized mean difference (SMD)=-0.06 mg/dL; 95% CI, −0.24, 0.12; P=0.530) in adults. There was a significant between-study heterogeneity in Apo A1 (I2=89.3%, P<0.001) and Apo B100 (I2=57.1%, P=0.030). However, significant increase in Apo A1 in daily dosage of vitamin D (SMD=0.56 mg/dL; 95% CI, 0.02, 1.11; P=0.044) and ≤12 weeks of supplementation duration (SMD=0.71 mg/dL; 95% CI, 0.08, 1.34; P=0.028) was observed. No significant effects of vitamin D on Apo A1 and Apo B100 levels after subgroup analysis by mean age, gender, study population, dosage and duration of study. Overall, daily vitamin D supplementation and ≤12 weeks of supplementation might have beneficial effects in increasing Apo A1 levels, however, future high-quality trials considering these a primary outcome are required.

scholarly journals The impact of informing diagnosis on quality of life in patients with cancer: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Miao Wan ◽  
Xianggui Luo ◽  
Juan Wang ◽  
Louis.B NDZANA MVOGO ◽  
Chen Chang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Cognitive Activity ◽  
Biomedical Literature ◽  
Cochrane Central Register ◽  
Patients With Cancer ◽  
General Quality ◽  
The Impact

Abstract Objective To assess the impact of informing diagnosis and disease status on the quality of life in patients with cancer Method We searched the follow databases, Pubmed, CENTRAL(Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase, CBM (Chinese Biomedical Literature database), WANFANG database (Chinese Medicine Premier), and CNKI (China National Knowledge Infrastructure). And the terms used are as follows: neoplasm, cancer, tumour, tumor, carcinoma, disclosure, truth telling, breaking bad news, knowledge, knowing, awareness, quality of life, QOL. Pairs of reviewers independently screened documents and extracted the data. Meta-analysis was conducted by Revman 5.0 software. Results There were 11740 records retrieved from databases and 23 studies were included finally. Meta-analysis of informed and uniformed cancer patients revealed no differences in both the general quality of life and symptoms of fatigue, pain, dyspnea, insomnia, appetite loss and diarrhea (P>0.05). Additionally, no difference in physical function, role function, cognitive activity and emotional function between the above 2 groups(P>0.05) were found. On the vitality area, the patients who were totally informed about their diagnosis had higher vitality than the uniformed patients. However, patients aware about their illnesses seemed to get lower scores in social function. Between the partly informed of the diagnosis and uninformed cancer patients, there were no differences in general quality of life, function domains and disease-related symptoms (P>0.05). Conclusion Informing the cancer patients their diagnosis may not have a bad effect on their quality of life. PROSPERO registration number CRD42017060073.

scholarly journals Quality of life in cancer patients treated with mistletoe: a systematic review and meta-analysis

2019 ◽  
Author(s):  
Martin Loef ◽  
Harald Walach
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cancer Patients ◽  
Positive Impact ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Sensitivity Analyses ◽  
Data Sets ◽  
Mistletoe Extracts

AbstractBackgroundMistletoe extracts are used as an adjunct therapy for cancer patients, but there is dissent as to whether this therapy has a positive impact on quality of life (QoL).MethodsWe conducted a systematic review searching in several databases (Medline, Embase, CENTRAL, CINAHL, PsycInfo, Science Citation Index, clinicaltrials.gov, opengrey.org) by combining terms that cover the fields of “neoplasm”, “quality of life” and “mistletoe”. We included prospective controlled trials that compared mistletoe extracts with a control in cancer patients and reported QoL or related dimensions. The quality of the studies was assessed with the Cochrane Risk of Bias tool version 2.We conducted a quantitative meta-analysis.ResultsWe included 26 publications with 30 data sets. The studies were heterogeneous. The pooled standardized mean difference (random effects model) for global QoL after treatment with mistletoe extracts vs. control was d = 0.61 (95% CI 0.41-0.81; p<0,00001). The effect was stronger for younger patients, with longer treatment, in studies with lower risk of bias, in randomized and blinded studies. Sensitivity analyses support the validity of the finding. 50% of the QoL subdomains (e.g. pain, nausea) show a significant improvement after mistletoe treatment. Most studies have a high risk of bias or at least raise some concern.ConclusionMistletoe extracts produce a significant, medium-sized effect on QoL in cancer. Risk of bias in the analyzed studies is likely due to the specific type of treatment, which is difficult to blind; yet this risk is unlikely to affect the outcome.PROSPERO registration numberCRD42019137704

scholarly journals The impact of informing diagnosis on quality of life in patients with cancer: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Miao Wan ◽  
Xianggui Luo ◽  
Louis.B NDZANA MVOGO ◽  
Juan Wang ◽  
Chen Chang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Cognitive Activity ◽  
Biomedical Literature ◽  
Cochrane Central Register ◽  
Patients With Cancer ◽  
General Quality ◽  
The Impact

Abstract Objective To assess the impact of informing diagnosis and disease status on the quality of life in patients with cancer Method We searched the follow databases, Pubmed, CENTRAL(Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase, CBM (Chinese Biomedical Literature database), WANFANG database (Chinese Medicine Premier), and CNKI (China National Knowledge Infrastructure). And the terms used are as follows: neoplasm, cancer, tumour, tumor, carcinoma, disclosure, truth telling, breaking bad news, knowledge, knowing, awareness, quality of life, QOL. Pairs of reviewers independently screened documents and extracted the data. Meta-analysis was conducted by Revman 5.0 software. Results There were 11740 records retrieved from databases and 23 studies were included finally. Meta-analysis of informed and uniformed cancer patients revealed no differences in both the general quality of life and symptoms of fatigue, pain, dyspnea, insomnia, appetite loss and diarrhea (P>0.05). Additionally, no difference in physical function, role function, cognitive activity and emotional function between the above 2 groups(P>0.05) were found. On the vitality area, the patients who were totally informed about their diagnosis had higher vitality than the uniformed patients. However, patients aware about their illnesses seemed to get lower scores in social function. Between the partly informed of the diagnosis and uninformed cancer patients, there were no differences in general quality of life, function domains and disease-related symptoms (P>0.05). Conclusion Informing the cancer patients their diagnosis may not have a bad effect on their quality of life. PROSPERO registration number CRD42017060073.

scholarly journals The Experiences of Cancer-Related Fatigue among Adult Cancer Patients: A Systematic Review

Jurnal NERS ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. 35
Author(s):  
I Komang Leo Triandana Arizona ◽  
Tintin Sukartini ◽  
Ferry Efendi ◽  
Primalova Septiavy Estiadewi ◽  
Ni Putu Dian Ayu Anggraeni
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cancer Patients ◽  
Future Research ◽  
Subjective Feeling ◽  
Structured Interviews ◽  
Cancer Related Fatigue ◽  
Patient Reported ◽  
The Impact

Introduction: Cancer-related fatigue (CRF) is one of the symptoms commonly experienced and it is a subjective feeling felt by cancer patients. The aim of this systematic review was to summarize how fatigue has been described from the perspective of adult cancer patients, the impact of fatigue on their quality of life, what the patient reported as contributing factors and potential coping strategies to reduce fatigue.Methods: A systematic review is in line with PRISMA guidelines. Five databases were systematically searched (Scopus, PubMed, Springerlink, ProQuest and Science Direct) from January 2009 to February 2019 for qualitative studies describing the experience of adult cancer patients using a predefined search strategy and any relevant keywords.Results: In total, 13 out of 4692 studies were included. The ages of the included patient cancer ranged from 26 to 84 years. The majority of studies used in-depth interviews and semi-structured interviews to elicit the participant’s experiences of fatigue. Four themes were identified: the perception of cancer-related fatigue, the etiology of cancer fatigue, impact and coping strategies.Conclusion: Fatigue is impactful on quality of life from the perspective of cancer patients. Future research should focus on the prospective exploration of the impact of fatigue on woman's and men's health and identifying approaches to reduce fatigue. 

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