scholarly journals The Treatment Efficacy of Transparasacral Approach For Presacral Tumor: A Single Center Experience

2021 ◽  
Author(s):  
Jian Li ◽  
Xu Han ◽  
Hongyu He ◽  
Yao Sun ◽  
Jiannan Li
Keyword(s):  
Treatment Efficacy ◽  
Clinical Symptoms ◽  
Surgical Approaches ◽  
Intestinal Fistula ◽  
Presacral Space ◽  
Tailgut Cyst ◽  
Single Center Experience ◽  
Retrorectal Tumors ◽  
Short And Long Term

Abstract Background: Presacral tumors, also known as retrorectal tumors, locate in the presacral space and are clinically rare and the approaches for the diagnosis and treatment of presacral tumors are still deficient. The four accepted surgical approaches for presacral tumors include transabdominal approach, sacrococcygeal approach, perineal approach, and combined approach. This study aims to evaluate the treatment efficacy of transparasacral approach for presacral tumors.Methods: 23 patients (7 males and 16 females) who are diagnosed with presacral tumors and receive surgery in transsacral approach at our department were chosen. The gender, age, body mass index (BMI), and clinical symptoms were recorded. The clinical data, postoperative complications, and short and long-term rehabilitation data were recorded and analyzed. Results: The surgery was performed smoothly and the patients recovered well without signs of intestinal fistula, abdominal and pelvic infection, lung infection, organ dysfunction, or organ failure. The incision edema occurred in only one patient. In terms of the histopathological types, presacral tumors can be classified into tailgut cyst (n=10), epidermoid cyst (n=5), teratoma (n=3), and lipoma (n=10). One patient diagnosed with tailgut cyst was accompanied by adenocarcinoma transition. Tumor recurrence didn’t occur in any patients. In addition, no patients complained about dysuria, sacrococcygeal sensory disturbance, or sacrococcygeal and perineal discomfort.Conclusions: Surgical resection with transparasacral approach is effective for the treatment of presacral tumors with the advantages of high safety, good treatment efficacy, few complications, good oncological prognosis, and fast recovery.

scholarly journals The Treatment Efficacy of Transparasacral Approach For Presacral Tumor: A Single Center Experience

2021 ◽  
Author(s):  
Min Wang ◽  
Yongping Yang ◽  
Linxian Zhao ◽  
Hongyu He ◽  
Jiannan Li
Keyword(s):  
Treatment Efficacy ◽  
Clinical Symptoms ◽  
Surgical Approaches ◽  
Intestinal Fistula ◽  
Presacral Space ◽  
Tailgut Cyst ◽  
Single Center Experience ◽  
Retrorectal Tumors ◽  
Short And Long Term

Abstract Background: Presacral tumors, also known as retrorectal tumors, locate in the presacral space and are clinically rare and the approaches for the diagnosis and treatment of presacral tumors are still deficient. The four accepted surgical approaches for presacral tumors include transabdominal approach, sacrococcygeal approach, perineal approach, and combined approach. This study aims to evaluate the treatment efficacy of transparasacral approach for presacral tumors.Methods: 23 patients (7 males and 16 females) who are diagnosed with presacral tumors and receive surgery in transsacral approach at our department were chosen. The gender, age, body mass index (BMI), and clinical symptoms were recorded. The clinical data, postoperative complications, and short and long-term rehabilitation data were recorded and analyzed. Conclusions: The surgery was performed smoothly and the patients recovered well without signs of intestinal fistula, abdominal and pelvic infection, lung infection, organ dysfunction, or organ failure. The incision edema occurred in only one patient. In terms of the histopathological types, presacral tumors can be classified into tailgut cyst (n=10), epidermoid cyst (n=5), teratoma (n=3), and lipoma (n=10). One patient diagnosed with tailgut cyst was accompanied by adenocarcinoma transition. Tumor recurrence didn’t occur in any patients. In addition, no patients complained about dysuria, sacrococcygeal sensory disturbance, or sacrococcygeal and perineal discomfort. Surgical resection with transparasacral approach is effective for the treatment of presacral tumors with the advantages of high safety, good treatment efficacy, few complications, good oncological prognosis, and fast recovery.

scholarly journals The Treatment Efficacy of Transparasacral Approach for Presacral Tumor: A Single Center Experience

2021 ◽  
Author(s):  
Min Wang ◽  
Guoliang Liu ◽  
Linxian Zhao ◽  
Hongyu He ◽  
Jiannan Li
Keyword(s):  
Treatment Efficacy ◽  
Clinical Symptoms ◽  
Surgical Approaches ◽  
Intestinal Fistula ◽  
Presacral Space ◽  
Tailgut Cyst ◽  
Single Center Experience ◽  
Retrorectal Tumors ◽  
Short And Long Term

Abstract Background Presacral tumors, also known as retrorectal tumors, locate in the presacral space and are clinically rare and the approaches for the diagnosis and treatment of presacral tumors are still deficient. The four accepted surgical approaches for presacral tumors include transabdominal approach, sacrococcygeal approach, perineal approach, and combined approach. This study aims to evaluate the treatment efficacy of transparasacral approach for presacral tumors. Methods 23 patients (7 males and 16 females) who are diagnosed with presacral tumors and receive surgery in transsacral approach at our department were chosen. The gender, age, body mass index (BMI), and clinical symptoms were recorded. The clinical data, postoperative complications, and short and long-term rehabilitation data were recorded and analyzed. Conclusions The surgery was performed smoothly and the patients recovered well without signs of intestinal fistula, abdominal and pelvic infection, lung infection, organ dysfunction, or organ failure. The incision edema occurred in only one patient. In terms of the histopathological types, presacral tumors can be classified into tailgut cyst (n = 10), epidermoid cyst (n = 5), teratoma (n = 3), and lipoma (n = 10). One patient diagnosed with tailgut cyst was accompanied by adenocarcinoma transition. Tumor recurrence didn’t occur in any patients. In addition, no patients complained about dysuria, sacrococcygeal sensory disturbance, or sacrococcygeal and perineal discomfort. Surgical resection with transparasacral approach is effective for the treatment of presacral tumors with the advantages of high safety, good treatment efficacy, few complications, good oncological prognosis, and fast recovery.

Early Gallbladder Carcinoma: A Single-Center Experience

2006 ◽  
Vol 92 (6) ◽  
pp. 487-490 ◽  
Author(s):  
Vincenzo Cangemi ◽  
Enrico Fiori ◽  
Cristina Picchi ◽  
Alessandro De Cesare ◽  
Roberto Cangemi ◽  
...  
Keyword(s):  
Gallbladder Carcinoma ◽  
Tnm Classification ◽  
Muscularis Propria ◽  
Surgical Approaches ◽  
Term Survival ◽  
Simple Cholecystectomy ◽  
Single Center Experience ◽  
Appropriate Treatment ◽  
Extended Cholecystectomy

Aims and background Controversy continues regarding the best surgical treatment for early gallbladder carcinoma defined as a tumor confined to the mucosa (pT1a) or to the muscularis propria (pT1 b) according to the TNM classification. This study evaluates the effectiveness of different surgical approaches in patients with early gallbladder carcinoma in terms of long-term survival. Materials and methods From 1980 to 2001, 175 patients with gallbladder carcinoma were admitted to our department. Fifteen of them underwent resections for early gallbladder carcinoma: 4 patients for pT1a tumors and 11 patients for pT1b tumors. All patients with pT1a tumors and 8 patients with pT1b tumors underwent simple cholecystectomy. The remaining 3 patients with pT1 b tumors underwent extended cholecystectomy. Results The 5-10 year cumulative survival rate was 100% for patients with pT1a tumors, 37.5% for patients with pT1b tumors who underwent simple cholecystectomy, and 100% for patients with pT1b tumors who underwent extended cholecystectomy. Conclusions Simple cholecystectomy is the appropriate treatment for patients with pT1a tumors, whereas patients with pT1b tumors require an extended cholecystectomy.

scholarly journals P2.09-02 Exploring the Features of the Short and Long-Term Survivors for Lung Adenocarcinoma: A Single Center Experience

2019 ◽  
Vol 14 (10) ◽  
pp. S768-S769
Author(s):  
L. Ventura ◽  
L. Gnetti ◽  
C. Braggio ◽  
G. Bocchialini ◽  
M. Tiseo ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Single Center ◽  
Single Center Experience ◽  
Short And Long Term ◽  
Long Term Survivors

scholarly journals Short- and Long-term Outcomes Following Side-to-side Strictureplasty and its Modification Over the Ileocaecal Valve for Extensive Crohn’s Ileitis

2020 ◽  
Vol 14 (10) ◽  
pp. 1378-1384 ◽  
Author(s):  
G Bislenghi ◽  
M Ferrante ◽  
J Sabino ◽  
B Verstockt ◽  
B Martin-Perez ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Long Term Outcomes ◽  
Comprehensive Complication Index ◽  
Clinical Recurrence ◽  
Ileocaecal Valve ◽  
Surgical Recurrence ◽  
Endoscopic Remission ◽  
Short And Long Term

Abstract Background and Aims Postoperative recurrence remains a challenging problem in patients with Crohn’s disease [CD]. To avoid development of short bowel syndrome, strictureplasty techniques have therefore been proposed. We evaluated short- and long-term outcomes of atypical strictureplasties in CD patients with extensive bowel involvement. Methods Side-to-side isoperistaltic strictureplasty [SSIS] was performed according to the Michelassi technique or modification of this over the ileocaecal valve [mSSIS]. Ninety-day postoperative morbidity was assessed using the comprehensive complication index [CCI]. Clinical recurrence was defined as symptomatic, endoscopically or radiologically confirmed, stricture/inflammatory lesion requiring medical treatment or surgery. Surgical recurrence was defined as the need for any surgical intervention. Endoscopic remission was defined as ≤i1, according to the modified Rutgeerts score. Deep remission was defined as the combination of endoscopic remission and absence of clinical symptoms. Perioperative factors related to clinical recurrence were evaluated. Results A total of 52 CD patients [SSIS n = 12; mSSIS n = 40] were included. No mortality occurred. Mean CCI was 10.3 [range 0–33.7]. Median follow-up was 5.9 years [range 0.8–9.9]. Clinical recurrence [19 patients] was 29.7% and 39.6% after 3 and 5 years, respectively. Surgical recurrence [seven patients] was 2% and 14.1% after 3 and 5 years, respectively. At the end of the follow-up, 92% of patients kept the original strictureplasty and deep remission was observed in 25.7% of the mSSIS patients. None of the perioperative variables considered showed a significant association with clinical recurrence. Conclusions SSIS is safe, effective, and provides durable disease control in patients with extensive CD ileitis.

scholarly journals Percutaneous Closure of PFO in Patients with Reduced Oxygen Saturation at Rest and during Exercise: Short- and Long-Term Results

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Céline De Cuyper ◽  
Tristan Pauwels ◽  
Eric Derom ◽  
Michel De Pauw ◽  
Daniël De Wolf ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Clinical Symptoms ◽  
Systemic Circulation ◽  
Percutaneous Closure ◽  
Long Term Results ◽  
Sf 36 ◽  
Short And Long Term

Background. A patent foramen ovale (PFO) is a rare cause of hypoxemia and clinical symptoms of dyspnea. Due to a right-to-left shunt, desaturated blood enters the systemic circulation in a subset of patients resulting in dyspnea and a subsequent reduction in quality of life (QoL). Percutaneous closure of PFO is the treatment of choice. Objectives. This retrospective multicentre study evaluates short- and long-term results of percutaneous closure of PFO in patients with dyspnea and/or reduced oxygen saturation. Methods. Patients with respiratory symptoms were selected from databases containing all patients percutaneously closed between January 2000 and September 2018. Improvement in dyspnea, oxygenation, and QoL was investigated using pre- and postprocedural lung function parameters and two postprocedural questionnaires (SF-36 and PFSDQ-M). Results. The average follow-up period was 36 [12–43] months, ranging from 0 months to 14 years. Percutaneous closure was successful in 15 of the 16 patients. All patients reported subjective improvement in dyspnea immediately after device deployment, consistent with their improvement in oxygen saturation (from 90 ± 6% to 94 [92–97%] on room air and in upright position) (p<0.05). Both questionnaires also indicated an improvement of dyspnea and QoL after closure. The two early and two late deaths were unrelated to the procedure. Conclusion. PFO-related dyspnea and/or hypoxemia can be treated successfully with a percutaneous intervention with long-lasting benefits on oxygen saturation, dyspnea, and QoL.

Short- and long-term outcomes of laparoscopic organ-sparing resection in pancreatic neuroendocrine tumors: a single-center experience

2017 ◽  
Vol 31 (10) ◽  
pp. 3847-3857 ◽  
Author(s):  
Javier A. Cienfuegos ◽  
Joseba Salguero ◽  
Jorge M. Núñez-Córdoba ◽  
Miguel Ruiz-Canela ◽  
Alberto Benito ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Pancreatic Neuroendocrine Tumors ◽  
Single Center ◽  
Long Term Outcomes ◽  
Single Center Experience ◽  
Short And Long Term ◽  
Organ Sparing

scholarly journals Good control of diffuse brain metastasis with lapatinib plus capecitabine in a patient with HER2-positive breast cancer

ABOUTOPEN ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 39-45
Author(s):  
Giovanni Faggioni
Keyword(s):  
Breast Carcinoma ◽  
Clinical Symptoms ◽  
Whole Brain Radiotherapy ◽  
Good Control ◽  
Tumor Burden ◽  
Her2 Positive ◽  
Brain Radiotherapy ◽  
Short And Long Term ◽  
Indolent Disease

S We present the case of a patient affected by HER2-positive breast carcinoma, relapsed at supraclavicular and mediastinal lymph nodes level, after three and eight years from initial diagnosis. These relapses were successfully treated by local radiotherapy, hormone therapy and trastuzumab. After 10 years from onset, the patient developed cerebral progression with a number of seizable lesions, overt clinical symptoms. To avoid the short- and long-term side effects of whole brain radiotherapy, the patient is initially treated with lapatinib and capecitabine in light of the favorable data on the efficacy of this combination on brain metastases from HER2-positive breast carcinoma. This therapy results in a considerable lesions reduction, allowing to postpone the panencephalic radiotherapy to a later time with a lower tumor burden. The response to radiotherapy is significant and sustanined for a progression-free interval of about 10 months. This case suggests that lapatinib may represent the treatment of choice in cases of indolent disease, characterized by long progression free intervals with minor symptoms with the aim to postpone the use of more invasive treatments (Oncology).

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